LOCUS       NM_001079886            1539 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus CUE domain containing 2 (Cuedc2), mRNA.
ACCESSION   NM_001079886 XM_001067247 XM_215274
VERSION     NM_001079886.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Huang,Y., Xiao,X., Xiao,H., Hu,Z. and Tan,F.
  TITLE     CUEDC2 ablation enhances the efficacy of mesenchymal stem cells in
            ameliorating cerebral ischemia/reperfusion insult
  JOURNAL   Aging (Albany NY) 13 (3), 4335-4356 (2021)
   PUBMED   33494071
  REMARK    GeneRIF: CUEDC2 ablation enhances the efficacy of mesenchymal stem
            cells in ameliorating cerebral ischemia/reperfusion insult.
REFERENCE   2  (bases 1 to 1539)
  AUTHORS   Chen,Y., Wang,S.X., Mu,R., Luo,X., Liu,Z.S., Liang,B., Zhuo,H.L.,
            Hao,X.P., Wang,Q., Fang,D.F., Bai,Z.F., Wang,Q.Y., Wang,H.M.,
            Jin,B.F., Gong,W.L., Zhou,T., Zhang,X.M., Xia,Q. and Li,T.
  TITLE     Dysregulation of the miR-324-5p-CUEDC2 axis leads to macrophage
            dysfunction and is associated with colon cancer
  JOURNAL   Cell Rep 7 (6), 1982-1993 (2014)
   PUBMED   24882011
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC127518.1.
            
            On or before Jan 5, 2007 this sequence version replaced
            XM_215274.4, XM_001067247.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC127518.1, SRR8487230.80015.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..1539
                     /gene="Cuedc2"
                     /note="CUE domain containing 2"
                     /db_xref="GeneID:294009"
                     /db_xref="RGD:1308096"
     exon            1..545
                     /gene="Cuedc2"
                     /inference="alignment:Splign:2.1.0"
     exon            546..629
                     /gene="Cuedc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             556..1359
                     /gene="Cuedc2"
                     /codon_start=1
                     /product="CUE domain-containing protein 2"
                     /protein_id="NP_001073355.1"
                     /db_xref="GeneID:294009"
                     /db_xref="RGD:1308096"
                     /translation="MELERIVSSALFAFVQTHLPEADLSGLDEVIFSYVLGVLEDLGP
                     SGPSEENFDMEAFIEMMEAYVPGFAHIHRGIIEDMVQTLSVQLSSARNKETLRRPEKL
                     KEESRPPAATGNTQDEAAAAEEEQPGVDVLLEVFPTCSMEQAQWVLAKARGNLEEAVQ
                     MLIEGKEEGPPGWGGPNQDLPRRLRGPRKEELKSFILQKYMMVDRAEDQKTHRPMAPK
                     EAPKKLIRYIDNQVVSTKGERFKDVRNPETEEMKATYINLKPARKYRFH"
     exon            630..773
                     /gene="Cuedc2"
                     /inference="alignment:Splign:2.1.0"
     exon            774..835
                     /gene="Cuedc2"
                     /inference="alignment:Splign:2.1.0"
     exon            836..909
                     /gene="Cuedc2"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1089
                     /gene="Cuedc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1090..1151
                     /gene="Cuedc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1212
                     /gene="Cuedc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1513
                     /gene="Cuedc2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacacagggt acctacactt catggtgttc ccttacaaca cccccccccg gggggggtgt
       61 cggccggacc cctttctcta attgtctccg tggcctgtat ggaggaacat ctagtttgtt
      121 caggcctatc tcgtcacgtg actcaccccc ttccactggc ggctgctgca tcgctgtcct
      181 ccggcagcta ttgtgaaagt ttttgagtgc cctgctaacg gttataaaaa gctcttgctt
      241 caagggtcgg ccgtcaaggg gatcctactt tctgtgcttc acctcccgtg gtttgtgcac
      301 ttgcctaact ttgagtggcc ggatcccttg ttcctcacaa tggctttggt actaagacct
      361 ggcgtgggaa tcaaggtgaa atagtatttg ctaagtcctt cattacgctt catcgagtct
      421 ttactaaagg gcacggaaga agtagtgaag acctctgggc taaggacccc tttactccct
      481 tagcttctca gggctccttc ccacattgct tcccaggaat tctccatcca cgtggcctgc
      541 tctcaaagac agagcatgga gttggagagg atcgtcagtt cagccctctt tgccttcgtt
      601 cagacacacc tcccagaggc agacctcagt ggcttggatg aggtcatctt ctcctatgtg
      661 cttggggtcc tggaggacct gggcccctca gggccatcag aggagaactt tgatatggag
      721 gctttcattg agatgatgga ggcttatgtg cctggctttg cccacatcca caggggtata
      781 atagaagaca tggtgcagac gctctcggtg cagctgagca gtgctaggaa caaagagacc
      841 ctgaggcgac ctgaaaagct caaggaagag agcaggcctc ctgctgctac tgggaacacc
      901 caagatgagg cagctgctgc tgaggaagaa cagccaggag tagacgtact cttggaggtg
      961 ttccctacct gttctatgga gcaggcccag tgggtgctgg ccaaagctcg ggggaacctg
     1021 gaagaagctg tgcagatgct gatagagggc aaggaagagg ggcctccagg ctggggtggc
     1081 ccaaatcagg atttacccag acgcctcaga ggcccccgga aggaggagtt gaagtctttc
     1141 atccttcaga agtacatgat ggtggacagg gcagaggacc agaagactca cagacctatg
     1201 gctcccaagg aggcccccaa gaagctgatc cgatacattg acaaccaagt agtgagcacc
     1261 aaaggagagc gattcaaaga tgtacggaac cccgaaactg aggagatgaa ggccacatac
     1321 atcaacctca agccggccag aaagtaccgc ttccactgag gcactggctg gactctgcca
     1381 ggcatcacag atcccagaag gatgcagaaa ccttcccgtc caccctaccc cttctctatg
     1441 cctttgctct agtgttaatt tattcttgga gcttccttca acagcacagt aaaggttgtc
     1501 caaggaaggt gtaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
