LOCUS       NM_053332              11331 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus cubilin (Cubn), mRNA.
ACCESSION   NM_053332
VERSION     NM_053332.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 11331)
  AUTHORS   Romi,M.M., Anggorowati,N., Maulida,D.S., Suskalanggeng,M.W.A.H.,
            Setyaningsih,W.A.W., Sari,D.C.R. and Arfian,N.
  TITLE     Upregulation of Megalin, Cubilin, NGAL mRNA expression in kidney
            may represent tubular injury and apoptosis in chronic condition of
            rat diabetic model
  JOURNAL   Med J Malaysia 76 (1), 87-92 (2021)
   PUBMED   33510115
  REMARK    GeneRIF: Upregulation of Megalin, Cubilin, NGAL mRNA expression in
            kidney may represent tubular injury and apoptosis in chronic
            condition of rat diabetic model.
REFERENCE   2  (bases 1 to 11331)
  AUTHORS   Park,H.S., Kim,I.J., Kim,E.G., Ryu,C.S., Lee,J.Y., Ko,E.J.,
            Park,H.W., Sung,J.H. and Kim,N.K.
  TITLE     A study of associations between CUBN, HNF1A, and LIPC gene
            polymorphisms and coronary artery disease
  JOURNAL   Sci Rep 10 (1), 16294 (2020)
   PUBMED   33004870
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 11331)
  AUTHORS   Martin,C.B., Oshiro,B.T., Sands,L.D., Kabir,S., Thorpe,D.,
            Clark,T.C., Yao,R. and Mata-Greenwood,E.
  TITLE     Vitamin-D dysregulation in early- and late-onset preeclampsia: A
            gestational-age matched study
  JOURNAL   J Steroid Biochem Mol Biol 203, 105729 (2020)
   PUBMED   32682061
REFERENCE   4  (bases 1 to 11331)
  AUTHORS   Briffa,J.F., Grinfeld,E., Jenkin,K.A., Mathai,M.L., Poronnik,P.,
            McAinch,A.J. and Hryciw,D.H.
  TITLE     Diet induced obesity in rats reduces NHE3 and Na(+) /K(+) -ATPase
            expression in the kidney
  JOURNAL   Clin Exp Pharmacol Physiol 42 (10), 1118-1126 (2015)
   PUBMED   26173747
REFERENCE   5  (bases 1 to 11331)
  AUTHORS   Liu,D., Wen,Y., Tang,T.T., Lv,L.L., Tang,R.N., Liu,H., Ma,K.L.,
            Crowley,S.D. and Liu,B.C.
  TITLE     Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved
            in the Tubular Cell Activation of NLRP3 Inflammasome and
            Tubulointerstitial Inflammation
  JOURNAL   J Biol Chem 290 (29), 18018-18028 (2015)
   PUBMED   26025362
  REMARK    GeneRIF: The inhibition of megalin/cubilin or lysosomal cathepsin B
            reduced albuminuria-induced NLRP3 inflammasome activation.
REFERENCE   6  (bases 1 to 11331)
  AUTHORS   Aminoff,M., Carter,J.E., Chadwick,R.B., Johnson,C., Grasbeck,R.,
            Abdelaal,M.A., Broch,H., Jenner,L.B., Verroust,P.J., Moestrup,S.K.,
            de la Chapelle,A. and Krahe,R.
  TITLE     Mutations in CUBN, encoding the intrinsic factor-vitamin B12
            receptor, cubilin, cause hereditary megaloblastic anaemia 1
  JOURNAL   Nat Genet 21 (3), 309-313 (1999)
   PUBMED   10080186
REFERENCE   7  (bases 1 to 11331)
  AUTHORS   Batuman,V., Verroust,P.J., Navar,G.L., Kaysen,J.H., Goda,F.O.,
            Campbell,W.C., Simon,E., Pontillon,F., Lyles,M., Bruno,J. and
            Hammond,T.G.
  TITLE     Myeloma light chains are ligands for cubilin (gp280)
  JOURNAL   Am J Physiol 275 (2), F246-F254 (1998)
   PUBMED   9691015
REFERENCE   8  (bases 1 to 11331)
  AUTHORS   Moestrup,S.K., Kozyraki,R., Kristiansen,M., Kaysen,J.H.,
            Rasmussen,H.H., Brault,D., Pontillon,F., Goda,F.O.,
            Christensen,E.I., Hammond,T.G. and Verroust,P.J.
  TITLE     The intrinsic factor-vitamin B12 receptor and target of teratogenic
            antibodies is a megalin-binding peripheral membrane protein with
            homology to developmental proteins
  JOURNAL   J Biol Chem 273 (9), 5235-5242 (1998)
   PUBMED   9478979
REFERENCE   9  (bases 1 to 11331)
  AUTHORS   Seetharam,B., Christensen,E.I., Moestrup,S.K., Hammond,T.G. and
            Verroust,P.J.
  TITLE     Identification of rat yolk sac target protein of teratogenic
            antibodies, gp280, as intrinsic factor-cobalamin receptor
  JOURNAL   J Clin Invest 99 (10), 2317-2322 (1997)
   PUBMED   9153271
REFERENCE   10 (bases 1 to 11331)
  AUTHORS   Levine,J.S., Allen,R.H., Alpers,D.H. and Seetharam,B.
  TITLE     Immunocytochemical localization of the intrinsic factor-cobalamin
            receptor in dog-ileum: distribution of intracellular receptor
            during cell maturation
  JOURNAL   J Cell Biol 98 (3), 1111-1118 (1984)
   PUBMED   6321516
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On Feb 11, 2021 this sequence version replaced NM_053332.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF022247.1, SRR26643287.34272.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-179               JAXUCZ010000017.1  81501516-81501694   c
            180-309             JAXUCZ010000017.1  81501004-81501133   c
            310-405             JAXUCZ010000017.1  81499530-81499625   c
            406-444             JAXUCZ010000017.1  81498916-81498954   c
            445-546             JAXUCZ010000017.1  81496457-81496558   c
            547-650             JAXUCZ010000017.1  81495737-81495840   c
            651-777             JAXUCZ010000017.1  81489265-81489391   c
            778-940             JAXUCZ010000017.1  81488283-81488445   c
            941-1072            JAXUCZ010000017.1  81486879-81487010   c
            1073-1174           JAXUCZ010000017.1  81485764-81485865   c
            1175-1296           JAXUCZ010000017.1  81481139-81481260   c
            1297-1483           JAXUCZ010000017.1  81479905-81480091   c
            1484-1596           JAXUCZ010000017.1  81478777-81478889   c
            1597-1831           JAXUCZ010000017.1  81477069-81477303   c
            1832-2013           JAXUCZ010000017.1  81473727-81473908   c
            2014-2176           JAXUCZ010000017.1  81471323-81471485   c
            2177-2367           JAXUCZ010000017.1  81470050-81470240   c
            2368-2512           JAXUCZ010000017.1  81461220-81461364   c
            2513-2691           JAXUCZ010000017.1  81460220-81460398   c
            2692-2857           JAXUCZ010000017.1  81459352-81459517   c
            2858-3074           JAXUCZ010000017.1  81458696-81458912   c
            3075-3205           JAXUCZ010000017.1  81456163-81456293   c
            3206-3395           JAXUCZ010000017.1  81447879-81448068   c
            3396-3556           JAXUCZ010000017.1  81445391-81445551   c
            3557-3738           JAXUCZ010000017.1  81444660-81444841   c
            3739-3895           JAXUCZ010000017.1  81443785-81443941   c
            3896-4083           JAXUCZ010000017.1  81441625-81441812   c
            4084-4234           JAXUCZ010000017.1  81421592-81421742   c
            4235-4416           JAXUCZ010000017.1  81405631-81405812   c
            4417-4591           JAXUCZ010000017.1  81400374-81400548   c
            4592-4761           JAXUCZ010000017.1  81397683-81397852   c
            4762-4921           JAXUCZ010000017.1  81379294-81379453   c
            4922-5035           JAXUCZ010000017.1  81377443-81377556   c
            5036-5146           JAXUCZ010000017.1  81375262-81375372   c
            5147-5275           JAXUCZ010000017.1  81373970-81374098   c
            5276-5408           JAXUCZ010000017.1  81373025-81373157   c
            5409-5614           JAXUCZ010000017.1  81368323-81368528   c
            5615-5799           JAXUCZ010000017.1  81367333-81367517   c
            5800-5992           JAXUCZ010000017.1  81365513-81365705   c
            5993-6190           JAXUCZ010000017.1  81365036-81365233   c
            6191-6337           JAXUCZ010000017.1  81360236-81360382   c
            6338-6528           JAXUCZ010000017.1  81357883-81358073   c
            6529-6712           JAXUCZ010000017.1  81357564-81357747   c
            6713-6887           JAXUCZ010000017.1  81353619-81353793   c
            6888-7066           JAXUCZ010000017.1  81352011-81352189   c
            7067-7276           JAXUCZ010000017.1  81350837-81351046   c
            7277-7417           JAXUCZ010000017.1  81350075-81350215   c
            7418-7599           JAXUCZ010000017.1  81349228-81349409   c
            7600-7771           JAXUCZ010000017.1  81343700-81343871   c
            7772-7978           JAXUCZ010000017.1  81342488-81342694   c
            7979-8128           JAXUCZ010000017.1  81340294-81340443   c
            8129-8250           JAXUCZ010000017.1  81338586-81338707   c
            8251-8476           JAXUCZ010000017.1  81337436-81337661   c
            8477-8664           JAXUCZ010000017.1  81335834-81336021   c
            8665-8821           JAXUCZ010000017.1  81330734-81330890   c
            8822-8971           JAXUCZ010000017.1  81328681-81328830   c
            8972-9172           JAXUCZ010000017.1  81325051-81325251   c
            9173-9302           JAXUCZ010000017.1  81322897-81323026   c
            9303-9520           JAXUCZ010000017.1  81320745-81320962   c
            9521-9729           JAXUCZ010000017.1  81308383-81308591   c
            9730-9892           JAXUCZ010000017.1  81302759-81302921   c
            9893-10098          JAXUCZ010000017.1  81302209-81302414   c
            10099-10246         JAXUCZ010000017.1  81299815-81299962   c
            10247-10428         JAXUCZ010000017.1  81299144-81299325   c
            10429-10594         JAXUCZ010000017.1  81297585-81297750   c
            10595-10830         JAXUCZ010000017.1  81295739-81295974   c
            10831-11331         JAXUCZ010000017.1  81293619-81294119   c
FEATURES             Location/Qualifiers
     source          1..11331
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.3"
     gene            1..11331
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /note="cubilin"
                     /db_xref="GeneID:80848"
                     /db_xref="RGD:68355"
     exon            1..179
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..10938
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /note="460 kDa receptor; glycoprotein 280; intrinsic
                     factor-cobalamin receptor; intrinsic factor-vitamin B12
                     receptor"
                     /codon_start=1
                     /product="cubilin precursor"
                     /protein_id="NP_445784.3"
                     /db_xref="GeneID:80848"
                     /db_xref="RGD:68355"
                     /translation="MSSQFLWGFVTLLMIAELDGKTGKPEQRGQKRIADLHQPRMTTE
                     EGNLVFLTSSTQNIEFRTGSLGKIKLNDEDLGECLHQIQRNKDDIIDLRKNTTGLPQN
                     ILSQVHQLNSKLVDLERDFQNLQQNVERKVCSSNPCLNGGTCVNLHDSFVCICPSQWK
                     GLFCSEDVNECVVYSGTPFGCQSGSTCVNTVGSFRCDCTPDTYGPQCASKYNDCEQGS
                     KQLCKHGICEDLQRVHHGQPNFHCICDAGWTTPPNGISCTEDKDECSLQPSPCSEHAQ
                     CFNTQGSFYCGACPKGWQGNGYECQDINECEINNGGCSQAPLVPCLNTPGSFSCGNCP
                     AGFSGDGRVCTPVDICSIHNGGCHPEATCSSSPVLGSFLPVCTCPPGYTGNGYGSNGC
                     VRLSNICSRHPCVNGQCIETVSSYFCKCDSGWSGQNCTENINDCSSNPCLNGGTCIDG
                     INGFTCDCTSSWTGYYCQTPQAACGGILSGTQGTFAYHSPNDTYIHNVNCFWIVRTDE
                     EKVLHVTFTFFDLESASNCPREYLQIHDGDSSADFPLGRYCGSRPPQGIHSSANALYF
                     HLYSEYIRSGRGFTARWEAKLPECGGILTDNYGSITSPGYPGNYPPGRDCVWQVLVNP
                     NSLITFTFGTLSLESHNDCSKDYLEIRDGPFHQDPVLGKFCTSLSTPPLKTTGPAARI
                     HFHSDSETSDKGFHITYLTTQSDLDCGGNYTDTDGELLLPPLSGPFSHSRQCVYLITQ
                     AQGEQIVINFTHVELESQMGCSHTYIEVGDHDSLLRKICGNETLFPIRSVSNKVWIRL
                     RIDALVQKASFRADYQVACGGMLRGEGFFRSPFYPNAYPGRRTCRWTISQPQRQVVLL
                     NFTDFQIGSSASCDTDYIEIGPSSVLGSPGNEKFCSSNIPSFITSVYNILYVTFVKSS
                     SMENRGFTAKFSSDKLECGEVLTASTGIIESPGHPNVYPRGVNCTWHVVVQRGQLIRL
                     EFSSFYLEFHYNCTNDYLEIYDTAAQTFLGRYCGKSIPPSLTSNSNSIKLIFVSDSAL
                     AHEGFSINYEAIDASSVCLYDYTDNFGMLSSPNFPNNYPSNWECIYRITVGLNQQIAL
                     HFTDFILEDYFGSQCVDFVEIRDGGYETSPLVGIYCGSVLPPTIISHSNKLWLKFKSD
                     AALTAKGFSAYWDGSSTGCGGNLTTPTGVLTSPNYPMPYYHSSECYWRLEASHGSPFE
                     LEFQDFHLEHHPSCSLDYLAVFDGPTTNSRLIDKLCGDTTPAPIRSNKDVVLLKLRTD
                     AGQQGRGFEINFRQRCDNVVIVNKTSGILESINYPNPYDKNQRCNWTIQATTGNTVNY
                     TFLGFDVESYMNCSTDYVELYDGPQWMGRYCGNNMPPPGATTGSQLHVLFHTDGINSG
                     EKGFKMQWFTHGCGGEMSGTAGSFSSPGYPNSYPHNKECIWNIRVAPGSSIQLTIHDF
                     DVEYHTSCNYDSLEIYAGLDFNSPRIAQLCSQSPSANPMQVSSTGNELAIRFKTDSTL
                     NGRGFNASWRAVPGGCGGIIQLSRGEIHSPNYPNNYRANTECSWIIQVERHHRVLLNI
                     TDFDLEAPDSCLTTYDGSSSTNARVASVCGRQQPPNSIIASGNSLFVRFRSGSSSQNR
                     GFRAEFREECGGRIMTDSSDTIFSPLYPHNYLHNQNCSWIIEAQPPFNHITLSFTHFQ
                     LQNSTDCTRDFVEILDGNDYDAPVQGRYCGFSLPHPIISFGNALTVRFVTDSTRSFEG
                     FRAIYSASTSSCGGSFYTLDGIFNSPDYPADYHPNAECVWNIASSPGNRLQLSFLSFN
                     LENSLNCNKDFVEIREGNATGHLIGRYCGNSLPGNYSSAEGHSLWVRFVSDGSGTGMG
                     FQARFKNIFGNNNIVGTHGKIASPFWPGKYPYNSNYKWVVNVDAYHIIHGRILEMDIE
                     PTTNCFYDSLKIYDGFDTHSRLIGTYCGTQTESFSSSRNSLTFQFSSDSSVSGRGFLL
                     EWFAVDVSDSTPPTIAPGACGGFMVTGDTPVHIFSPGWPREYANGADCIWIIYAPDST
                     VELNILSLDIEPQQSCNYDKLIVKDGDSDLSPELAVLCGVSPPGPIRSTGEYMYIRFT
                     SDTSVAGTGFNASFHKSCGGYLHADRGVITSPKYPDTYLPNLNCSWHVLVQTGLTIAV
                     HFEQPFQIQNRDSFCSQGDYLVLRNGPDNHSPPLGPSGRNGRFCGMYAPSTLFTSGNE
                     MFVQFISDSSNGGQGFKIRYEAKSLACGGTVYIHDADSDGYLTSPNYPANYPQHAECI
                     WILEAPPGRSIQLQFEDQFNIEDTPNCSVSYLELRDGANSNARLVSKLCGHTLPHSWV
                     SSRERIYLKFHTDGGSSYMGFKAKYSIASCGGTVSGDSGVIESIGYPTLPYANNVFCQ
                     WFIRGLPGHYLTLSFEDFNLQSSPGCTKDFVEIWENHTSGRVLGRYCGNSTPSSVDTS
                     SNVASVKFVTDGSVTASGFRLQFKSSRQVCGGDLHGPTGTFTSPNYPNPNPHARICEW
                     TITVQEGRRIVLTFTNLRLSTQPSCNSEHLIVFNGIRSNSPLLQKLCSRVNVTNEFKS
                     SGNTMKVVFFTDGSRPYGGFTASYTSTEDAVCGGFLPSVSGGNFSSPGYNGIRDYARN
                     LDCEWTLSNPNRENSSISIYFLELSIESHQDCTFDVLEFRVGDADGPLIEKFCSLSAP
                     TAPLVIPYPQVWIHFVSNERVEYTGFYIEYSFTDCGGIRTGDNGVISSPNYPNLYSAW
                     THCSWLLKAPEGHTITLTFSDFLLEAHPTCTSDSVTVRNGDSPGSPVIGRYCGQSVPR
                     PIQSGSNQLIVTFNTNNQGQTRGFYATWNTNALGCGGTFHSANGTIKSPHWPQTFPEN
                     SRCSWTVITHESKHWEISFDSNFRIPSSDSQCQNSFVKVWEGRLMINKTLLATSCGDV
                     APSPIVTSGNIFTAVFQSEEMAAQGFSASFISRCGRTFNTSTGDIISPNFPKQYDNNM
                     NCTYLIDADPQSLVILTFVSFHLEDRSAITGTCDHDGLHIIKGRNLSSTPLVTICGSE
                     TLRPLTVDGPVLLNFYSDAYTTDFGFKISYRAITCGGIYNESSGILRSPSYSYSNYPN
                     NLYCVYSLHVRSSRVIIIRFNDFDVAPSNLCAHDFLEVFDGPSIGNRSLGKFCGSTRP
                     QTVKSTNSSLTLLFKTDSSQTARGWKIFFRETIGPQQGCGGYLTEDNQSFVSPDSDSN
                     GRYDKGLSCIWYIVAPENKLVKLTFNVFTLEGPSSAGSCVYDYVQIADGASINSYLGG
                     KFCGSRMPAPFISSGNFLTFQFVSDVTVEMRGFNATYTFVDMPCGGTYNATSTPQNAS
                     SPHLSNIGRPYSTCTWVIAAPPQQQVQITVWDLQLPSQDCSQSYLELQDSVQTGGNRV
                     TQFCGANYTTLPVFYSSMSTAVVVFKSGVLNRNSQVQFSYQIADCNREYNQTFGNLKS
                     PGWPQNYDNNLDCTIILRAPQNHSISLFFYWFQLEDSRQCMNDFLEVRNGGSSTSPLL
                     DKYCSNLLPNPVFSQSNELYLHFHSDHSVTNNGYEIIWTSSAAGCGGTLLGDEGIFTN
                     PGFPDSYPNNTHCEWTIVAPSGRPVSVGFPFLSIDSSGGCDQNYLIVFNGPDANSPPF
                     GPLCGINTGIAPFYASSNRVFIRFHAEYTTRLSGFEIMWSS"
     exon            180..309
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            310..405
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            406..444
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            445..546
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            547..650
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            651..777
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            778..940
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1072
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1073..1174
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1175..1296
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..1483
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1484..1596
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1831
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            1832..2013
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            2014..2176
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            2177..2367
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            2368..2512
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            2513..2691
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            2692..2857
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            2858..3074
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            3075..3205
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            3206..3395
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            3396..3556
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            3557..3738
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            3739..3895
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            3896..4083
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            4084..4234
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            4235..4416
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            4417..4591
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            4592..4761
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            4762..4921
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            4922..5035
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            5036..5146
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            5147..5275
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            5276..5408
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            5409..5614
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            5615..5799
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            5800..5992
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            5993..6190
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            6191..6337
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            6338..6528
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            6529..6712
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            6713..6887
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            6888..7066
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            7067..7276
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            7277..7417
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            7418..7599
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            7600..7771
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            7772..7978
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            7979..8128
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            8129..8250
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            8251..8476
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            8477..8664
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            8665..8821
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            8822..8971
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            8972..9172
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            9173..9302
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            9303..9520
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            9521..9729
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            9730..9892
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            9893..10098
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            10099..10246
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            10247..10428
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            10429..10594
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            10595..10830
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
     exon            10831..11331
                     /gene="Cubn"
                     /gene_synonym="GP280; IFCR; MGA1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tggactcggt tggccggagt ggtctccctc ttgcctggcg agctgggagg ctggctgctg
       61 aggaacatgt cctcgcagtt tctctggggt tttgttactt tgttgatgat agctgaatta
      121 gatggcaaaa ctggaaagcc ggagcagagg ggacagaaaa ggatcgctga cctgcaccag
      181 cctcggatga ctacggagga gggaaactta gtatttctta caagctctac ccaaaacatt
      241 gaatttagaa ctggatccct ggggaaaatc aaattaaatg atgaagacct tggcgaatgt
      301 ttacaccaga tccagagaaa caaagatgat attatagatt taagaaagaa tacaactggc
      361 ctccctcaaa atatacttag tcaagtccac caacttaact cgaagctcgt ggatctggag
      421 agagattttc aaaacttaca gcagaatgtg gagagaaaag tttgcagtag caatccctgc
      481 cttaatggtg gcacctgcgt caacctgcac gactcctttg tgtgtatctg cccttctcag
      541 tggaagggtc tcttctgctc agaggatgtc aacgagtgtg tagtttactc aggaacaccc
      601 tttggctgcc agagtggatc cacctgtgtg aacacagtgg ggagtttcag atgtgactgc
      661 acgccggata cgtacggacc tcagtgtgca tccaaatata atgactgtga acagggctct
      721 aaacagctct gcaagcacgg catctgtgag gatttacagc gagttcacca tggacagccg
      781 aattttcact gcatctgtga tgctgggtgg acaacaccgc caaatggaat ctcctgcaca
      841 gaggacaaag acgaatgcag cctccagcct tcaccttgtt cggagcatgc gcagtgtttc
      901 aatacacaag gctccttcta ctgtggggcc tgccccaaag gttggcaggg aaatggttat
      961 gaatgccagg atatcaatga atgcgagatc aacaatggag gctgttccca ggcgccactg
     1021 gtcccatgcc tgaacacacc tggatcattc tcctgtggga actgtccagc aggtttcagt
     1081 ggtgacggga gagtgtgcac tcccgtggac atctgttcga tccacaatgg aggctgccat
     1141 ccagaggcaa cctgctcctc atctcctgtt ctagggtcct tcttgcctgt ctgcacctgt
     1201 cctccgggat atacaggaaa tggttacggg tctaatggat gtgtacgcct cagtaatatt
     1261 tgctcaaggc acccgtgtgt aaatggacag tgcatagaaa cagtatcaag ttatttctgt
     1321 aagtgtgact caggctggtc tggacagaac tgtacagaaa acattaatga ctgttcgagc
     1381 aacccctgtt tgaatggggg cacctgtatt gatggcatca atggcttcac ctgcgactgc
     1441 acaagctctt ggactggcta ttactgtcag actccccagg cagcttgcgg agggatcctc
     1501 tcagggacac aaggaacctt tgcctaccac agcccaaatg atacctatat tcacaatgtg
     1561 aactgtttct ggattgtcag aactgatgag gaaaaggttc tgcatgtcac cttcacgttt
     1621 tttgatttag aatcagcaag caattgtccc cgggagtacc ttcagattca tgatggagac
     1681 tcctcagcgg atttcccact tggtagatac tgtggctcca ggccccccca ggggatccac
     1741 agcagtgcca atgctctcta tttccatctc tactccgagt acataaggag tgggagaggc
     1801 tttacagcaa ggtgggaggc gaagctgcca gagtgtggcg gcatcctgac tgataattac
     1861 ggttctatta cgtctccggg gtaccctgga aactaccccc caggaagaga ttgtgtctgg
     1921 caggttttag tcaatcctaa ctccttgata acatttacct ttggaacctt gagcctggag
     1981 agccacaatg actgcagcaa agactatttg gagattcgag acggtccttt ccaccaagac
     2041 cctgttcttg ggaaattctg cacttccttg tctaccccac ccctcaagac taccggtcct
     2101 gcagcaagaa ttcatttcca ttctgactct gagaccagtg acaaaggctt ccacatcacc
     2161 tatctaacca cacagtcgga tctggactgt ggtgggaact acacagacac ggatggcgag
     2221 ctcctccttc ctcctttgtc tggtcctttc agtcacagca gacagtgtgt ctatctcatc
     2281 acccaagccc agggagaaca aatagttatc aacttcaccc atgtggagct ggagagccag
     2341 atgggctgtt ctcacactta catcgaggtt ggagaccatg acagcttact tcgaaagatc
     2401 tgtggcaatg aaaccttgtt ccccattaga tcagtttcta ataaagtctg gatcagattg
     2461 agaatagacg ctttagtcca gaaggctagt ttcagagctg actaccaagt tgcttgtggg
     2521 ggtatgttaa gaggagaagg attctttcgc tcacctttct atcctaacgc atatcctgga
     2581 cgaagaacct gtaggtggac catctcccaa ccccaaagac aagttgtcct tcttaacttc
     2641 actgactttc agatcggaag ttctgcctcc tgtgatacag attatattga gattggtccc
     2701 agctctgtct tgggatctcc tggaaatgag aagttttgta gctcaaacat accgtcattt
     2761 ataacatctg tatacaatat tctttatgtt acatttgtga aaagttcttc catggaaaat
     2821 cgtggcttca cggctaagtt cagcagtgac aaactagagt gtggagaagt tctcacggca
     2881 tctacaggaa ttatcgaaag tccaggtcat ccaaacgtct acccaagagg tgtaaattgt
     2941 acttggcatg tagtagtcca acgcggccaa ctgatccgtt tggagttcag ttccttttac
     3001 ctggagtttc attacaactg cacaaacgac tacctggaaa tttatgacac tgccgctcag
     3061 acttttcttg ggagatactg tggaaaatcc atcccgcctt ctcttaccag caactctaat
     3121 tcaataaagc tgatatttgt gtctgactcc gcccttgccc acgaaggctt ttccataaat
     3181 tatgaggcaa tcgatgcatc atcagtatgt ttatatgact atacagataa ttttgggatg
     3241 ctctcctccc cgaacttccc caataattac cccagtaact gggagtgcat ctacagaatc
     3301 actgtgggac tcaaccaaca gattgcattg catttcacag acttcatctt ggaggactat
     3361 tttgggtcac agtgtgtaga ttttgtagaa atcagagacg gaggctacga aacgtcgccg
     3421 cttgttggga tttactgtgg ctcagttttg cctcctacaa tcatctccca cagtaacaag
     3481 ctctggctaa agtttaagag tgacgccgca ctcacggcaa aggggttctc agcgtactgg
     3541 gacggatcat caacaggctg tggaggtaat ctcaccaccc ccacaggggt gctcacatcg
     3601 cccaactacc cgatgcccta ctaccacagc tccgaatgct actggcggct ggaagccagt
     3661 catggcagcc ctttcgagct ggaattccaa gacttccacc tggaacacca ccccagctgc
     3721 tctctggatt acttggccgt gtttgatggc ccgactacca actcccgact gatagataaa
     3781 ctgtgtgggg atacgacacc tgctcccatc cgttccaata aagacgtcgt attgttaaaa
     3841 ctgaggactg atgcaggtca gcaaggccgt ggctttgaga tcaacttccg gcagagatgt
     3901 gacaatgtgg tgatagtgaa caaaacctct ggcatcctgg agagcataaa ttatccaaat
     3961 ccctatgata agaaccaacg ttgtaactgg accatccaag caaccaccgg caacaccgtg
     4021 aactacacgt ttctgggatt tgatgtggaa agttacatga actgctccac agattatgta
     4081 gagctctatg atggaccaca atggatggga cgctactgtg gaaataacat gcccccacca
     4141 ggggctacaa caggctccca actccacgta ctgttccata cagatgggat caattctggg
     4201 gaaaaaggat ttaagatgca gtggttcact catggctgtg gtggagagat gtctggaacc
     4261 gcaggctcct tcagcagccc tgggtacccc aacagctatc ctcacaacaa agagtgtatc
     4321 tggaacattc gcgtggcccc agggagtagc attcagctca ccatccatga ctttgatgtg
     4381 gaatatcata caagctgcaa ctatgactcc ctggagatct atgcaggtct tgattttaac
     4441 tctccaagaa tagcccaact gtgttcccaa tcaccgtcag cgaaccccat gcaggtctcc
     4501 agcactggca atgaactagc aatccgattt aagacggata gcactttaaa tggaagaggt
     4561 ttcaatgcct cgtggcgagc agtccctgga ggttgtggtg ggattatcca gctttccaga
     4621 ggagagattc attctccaaa ttaccccaac aactacagag ctaacacaga gtgctcctgg
     4681 atcattcaag ttgagcgaca tcaccgtgtt ctcttgaata tcactgactt tgaccttgaa
     4741 gctccagatt cttgtcttac gacttatgat ggctcaagtt ccacaaacgc ccgtgtcgcc
     4801 agtgtgtgtg gaagacagca gccccctaac tctatcatcg cttcaggaaa cagcctcttt
     4861 gtgagattcc ggtctggatc ttccagccag aacaggggct tccgggctga attcagggaa
     4921 gagtgcggag gccgcatcat gaccgactct tccgatacta tcttctctcc actgtaccct
     4981 cacaactatc tacacaacca gaactgttcc tggataattg aagctcagcc tccattcaat
     5041 cacattactc tctcctttac tcactttcaa cttcaaaaca gcacagactg tacacgggac
     5101 tttgtagaaa ttttggatgg caacgactat gacgcacctg tccaaggccg ttactgtggt
     5161 ttctccctgc cccaccccat catatcattt ggcaatgccc taaccgtgag gtttgtcact
     5221 gattccacac gcagttttga gggtttccgt gccatctatt ctgcatcgac atcatcttgt
     5281 ggtggaagct tctacacact tgatggcatc ttcaatagcc ccgactaccc agcagactac
     5341 catccaaatg cagaatgtgt ctggaacatt gccagctccc ctggcaaccg cctgcaactg
     5401 tccttcctat ccttcaattt ggagaattct ctaaactgta acaaggattt tgtggaaatc
     5461 cgagaaggaa atgccacggg ccacttgatt ggacgatact gtggaaactc cctccctggg
     5521 aattattcgt cagctgaggg acatagtcta tgggtccgat ttgtctctga tggctcaggc
     5581 actggcatgg gcttccaggc caggttcaaa aatatatttg gcaataataa tattgtggga
     5641 actcatggga aaatcgcatc tcccttctgg cctggaaaat acccctacaa ctccaattac
     5701 aaatgggtgg taaatgtgga cgcatatcat attatccacg gtagaatctt agagatggac
     5761 atagaaccca caacgaactg cttttatgac agtttaaaga tttatgatgg atttgacact
     5821 cattcccgtc tcattggcac ttactgtggt acccagacag aatcctttag ctccagtaga
     5881 aactctctga cattccagtt ttcttccgac tcttctgtgt caggaagggg attccttctg
     5941 gagtggtttg cagtagatgt ttctgatagc acccctccca ccatcgctcc aggagcttgt
     6001 ggagggttta tggtgacggg agacactcct gtccatattt tctccccggg ttggcctaga
     6061 gagtatgcta atggtgctga ctgtatctgg atcatctatg ctcctgactc tactgtggaa
     6121 ctcaacattc tctccttgga catcgaaccg cagcagtcat gcaattatga caagctgatc
     6181 gtaaaagacg gagacagtga cttatcccca gagctggctg ttctgtgtgg cgtaagccct
     6241 cctgggccca tccggtcaac tggagaatac atgtacatcc gcttcacttc agacaccagc
     6301 gtcgcgggga caggcttcaa cgcctccttt cacaagagct gtggtggata tttgcatgca
     6361 gatcgaggag ttatcacatc ccccaagtat ccagacacct accttcccaa cctcaactgc
     6421 tcctggcatg ttctggtcca gactggtctg accatcgccg tccattttga gcagcctttc
     6481 cagattcaaa acagagactc tttttgcagt cagggggatt acttggtgct aagaaacgga
     6541 ccagataacc attctccacc actgggacct tctggaagaa atggtcgttt ctgcggaatg
     6601 tacgcaccgt ccactctgtt cacctcaggc aatgaaatgt ttgttcagtt catctcggac
     6661 agtagtaatg gtggacaagg gtttaagatc agatatgagg caaagagttt agcctgcggg
     6721 ggcactgtct acatccatga tgctgactct gacggatacc tgacctcccc caactaccct
     6781 gctaattatc cccaacatgc cgaatgcatt tggatcttag aggcgcctcc agggagaagc
     6841 atacagctcc aatttgaaga tcaattcaat attgaagaca cacccaactg ttctgtgagc
     6901 tatcttgaat tgcgtgacgg agccaactcg aatgcacgtc tggtttccaa gttgtgtggc
     6961 cacactctgc ctcatagctg ggtatcctcg agagaacgaa tatacttgaa gtttcacact
     7021 gacggtggtt ccagctacat gggattcaag gccaagtact ctatagcttc ctgtggagga
     7081 acagtctcag gggacagtgg agtcatcgag agcattggct acccgaccct tccgtatgca
     7141 aacaatgtgt tttgtcagtg gtttatccga ggcctcccag gacactacct cactctcagt
     7201 tttgaagatt ttaaccttca gagctctcct ggttgtacaa aagactttgt ggagatctgg
     7261 gaaaaccata cctctggaag agttctgggg agatattgtg gaaactccac tcctagcagt
     7321 gttgacactt ccagcaatgt tgcttccgtc aagtttgtca cagatggctc tgtcactgcc
     7381 tcaggattta ggctgcagtt taagtccagc agacaagtgt gtggtgggga tttacatggc
     7441 cctactggca catttacttc tcccaactac ccaaacccaa atcctcatgc ccggatctgt
     7501 gagtggacga tcactgtaca agaaggaagg cggatcgtcc tgacgtttac caacttgagg
     7561 ctgagtaccc agccatcttg taacagtgag cacctcatcg tattcaatgg cattagaagc
     7621 aactcgcccc tactacagaa actgtgcagc cgtgtgaatg tgaccaatga attcaaatct
     7681 tcaggaaaca ccatgaaagt ggtatttttc actgatggct cccggccgta tggaggcttc
     7741 actgcttcct acacctctac tgaagatgca gtgtgtggtg gatttcttcc aagtgtctcc
     7801 ggtggaaact tttcttctcc tggctataat ggaattcgtg attatgccag aaacctagac
     7861 tgtgaatgga ctctcagtaa tccaaatcgg gaaaattcat ccataagtat ctattttcta
     7921 gaactttcta ttgaaagtca tcaagactgt acatttgatg tcctagagtt tcgagtaggg
     7981 gatgctgatg ggcccctgat agagaagttc tgtagcctgt cagcaccaac agcgcccttg
     8041 gtcatcccct accctcaggt gtggatacac ttcgtcagca atgagcgtgt agaatatact
     8101 ggattctata tagagtactc ctttacagat tgtggtggaa tacggacagg tgacaatgga
     8161 gtgatctcaa gtcctaacta tccaaacttg tacagtgcat ggacccactg ttcatggctg
     8221 ctgaaagccc cagaaggtca caccatcact ctcacattca gtgactttct tcttgaggct
     8281 catccaactt gcacttcaga ctccgtcact gtcaggaatg gtgactcccc aggatcgccc
     8341 gtcataggac gatactgtgg acagtcagtc cctaggccga tacagtctgg ttccaaccaa
     8401 cttatagtga cttttaacac aaacaatcaa gggcaaactc gtggatttta tgcaacatgg
     8461 aacacaaacg ctttaggttg tgggggaaca ttccactcag ctaatggtac aatcaaatct
     8521 cctcactggc ctcagacatt cccagaaaac agcagatgct cctggacagt gatcactcac
     8581 gaaagtaaac actgggagat tagctttgac agcaatttcc gaatccccag cagtgacagc
     8641 cagtgtcaga acagcttcgt gaaggtttgg gaaggaaggt tgatgatcaa taagaccctg
     8701 ttagccacga gctgtggaga tgtggctcca agtcccattg tcacatcagg gaacattttc
     8761 actgctgtct tccaatctga ggagatggca gcccagggct tctctgcatc cttcattagc
     8821 cggtgcggac gcacattcaa tacctccact ggtgacatca tctctccaaa cttcccgaag
     8881 caatacgaca acaacatgaa ctgcacctac ctcatagacg ctgaccctca gtctctggtc
     8941 atcctgactt ttgtgtcctt tcatttggaa gatcgctcag ctatcaccgg aacctgtgat
     9001 catgatggct tgcacatcat caaaggtcgt aacctctctt ccactcctct cgtgaccata
     9061 tgtggttctg aaactttgcg tcccctcact gtggacggcc cagtgttgct caacttctat
     9121 tctgatgcat acaccacaga ctttggcttc aagatttcct acagagccat cacctgtggt
     9181 gggatctaca atgaatcctc tggaatcctt aggagccctt cctactcata cagcaactac
     9241 cccaacaacc tctactgtgt ctacagcctc catgttagaa gcagcagagt gataataatc
     9301 aggttcaatg atttcgatgt ggctccttcc aacctttgtg cacatgactt cctggaggtg
     9361 tttgatggtc ccagcattgg aaatcgatct cttggaaagt tctgtggttc cacgcgtcca
     9421 caaactgtta agagcaccaa tagcagcctg accctgctgt tcaagacaga ttcttctcaa
     9481 acagcaagag gttggaaaat atttttccgg gagacaatag ggccacagca gggatgtggt
     9541 ggatacctga ccgaggacaa ccagagcttt gtgtctcctg attctgattc gaatggacgc
     9601 tatgacaagg gtctcagctg catatggtac atagttgcac ctgaaaacaa actggttaag
     9661 ctcaccttca atgtgttcac tctggaggga ccatcgtcag ctgggagctg cgtctatgat
     9721 tatgtgcaga tagcagatgg cgcaagcata aactcatatt taggtggaaa attctgtggc
     9781 tcccgtatgc ctgccccatt tatctcttcc ggcaacttcc ttacgtttca gtttgtctct
     9841 gacgtaactg ttgaaatgag gggatttaat gcaacatata cctttgtgga catgccttgc
     9901 gggggaacat ataacgcaac ctcgacacct caaaatgcgt catcacctca tttatccaac
     9961 atcggacggc catactccac ctgtacttgg gtcatcgcag ctcccccaca gcagcaggtt
    10021 cagataactg tgtgggactt acagctgccc tcacaagact gctcacaaag ctacttagaa
    10081 cttcaggatt cagtacagac tggtggaaac cgggtgactc agttctgcgg tgcgaactat
    10141 acaaccttgc cagtgttcta ctcctcaatg agcactgcgg ttgtcgtttt caagtctgga
    10201 gttttaaaca gaaactcgca agtgcaattc tcctatcaga ttgcagattg caacagagaa
    10261 tacaaccaaa cgtttggcaa tctgaagagt cctgggtggc ctcagaacta tgacaataac
    10321 ctggactgca ccatcattct cagagccccg cagaaccaca gcatttccct ctttttctat
    10381 tggtttcagc tggaagattc aagacaatgc atgaatgatt tcttggaggt aagaaacggc
    10441 ggcagcagca cctcaccact gcttgacaag tactgtagca acctgctgcc caacccggtc
    10501 ttctctcaga gcaacgaact gtatctgcac tttcacagcg accactcagt caccaacaat
    10561 ggctatgaaa ttatttggac ctcctctgct gctggctgtg gagggactct tttgggcgac
    10621 gaagggatat tcaccaaccc tggctttcct gacagttacc cgaacaacac tcattgtgaa
    10681 tggaccattg ttgctccttc tggaaggcct gtctctgtcg ggtttccctt tctcagtatc
    10741 gactcttctg gtggctgtga ccagaactac ctcatagtct ttaatggtcc agacgccaac
    10801 tccccaccct ttggaccgtt gtgtggcatc aacactggga tagcgccctt ctatgcttca
    10861 tcaaatcggg tctttataag gtttcatgct gagtatacga cacgtctttc agggtttgaa
    10921 ataatgtgga gcagctgaat caggagagct gtgtataacc ccaggactct ggttctgccc
    10981 agtgctgtca gatgcaaccc tgcccagtac tcattctgct gttctcatcc ccgtctctgc
    11041 ctgcgtcatc aaacatggac tgagcttcta cagccttgac cagagaaagt gcacgactga
    11101 cttcatacat taggcgttct gaaggctttg atctactcag ctgtgcacac catctttact
    11161 ggatgccctg tttagccgac atcttctaaa atgttcttta aagggtggaa gttatcctgg
    11221 cacattgatg tacggtttta aaacttggtg atacaaatgg atgtattgtt tccactacaa
    11281 aagtcaaagt gcaggtaata aacatttctt cacatgtcta ctgtgagaaa a
//
