LOCUS       NM_001037094            1660 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Rattus norvegicus cytosolic thiouridylase subunit 2 (Ctu2), mRNA.
ACCESSION   NM_001037094 XM_214702
VERSION     NM_001037094.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1660)
  AUTHORS   Schlieker,C.D., Van der Veen,A.G., Damon,J.R., Spooner,E. and
            Ploegh,H.L.
  TITLE     A functional proteomics approach links the ubiquitin-related
            modifier Urm1 to a tRNA modification pathway
  JOURNAL   Proc Natl Acad Sci U S A 105 (47), 18255-18260 (2008)
   PUBMED   19017811
  REMARK    GeneRIF: Identifies a similar human protein that is involved in
            tRNA modification.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC107464.1.
            
            On Nov 7, 2005 this sequence version replaced XM_214702.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC107464.1, BC079393.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132263, SAMD00132265
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1660
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..1660
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /note="cytosolic thiouridylase subunit 2"
                     /db_xref="GeneID:292069"
                     /db_xref="RGD:1562594"
     exon            1..80
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     CDS             13..1599
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /note="cytosolic thiouridylase subunit 2 homolog"
                     /codon_start=1
                     /product="cytoplasmic tRNA 2-thiolation protein 2"
                     /protein_id="NP_001032171.1"
                     /db_xref="GeneID:292069"
                     /db_xref="RGD:1562594"
                     /translation="MCQAGEDYAGPAQREPPPVPRPSREQKCVKCAEGLPVVVIRAGD
                     AFCRDCFKAFYVHKFRAMLGKNRVIFPGEKVLLSWSGGPSSSSMVWQVLEGLSQDSAK
                     RLRFVPGVIYVDEGAACGQSLEDRVKTLAEVKRILGNTGFPFHVVALEEVFSLPPSVL
                     RRASQEPAGTEEAYKAAVDSFLQQQHVLGTEACASPAQGQGQLRPSHSQEPSGTVGHP
                     KDAQTEALSRLFKSIKTLTAKEELLQTLRTHLTVHVARSHGYRKVMTGESCTRLAIKL
                     MTNLALGRGAFLAWDTGFSDERHGDVVLVRPMRDHTLKEVAFYNRLFGVPSVFTPAID
                     TKAPEKASIHRLMEAFILKLQTLFPSTVSTVYRTSEKLVKAPREGCATGPSGPNCLLC
                     MCALDVDNADSATAFGAQSSSHLSQMLTAEAGTPTRPCCGAGEGQTQSCHRAVGRRED
                     AWACIIEQLCYSCRVNMKDLPSLDPLPPYVLTEAQLRSQRGSVSEEIQEYLIEEEEEE
                     DRAEPCEAMKQEAEDKGIGL"
     exon            81..155
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     exon            156..234
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     exon            235..294
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     exon            295..355
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     exon            356..465
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     exon            466..752
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     exon            753..888
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     exon            889..1020
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1112
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     exon            1113..1216
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..1355
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     exon            1356..1422
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     exon            1423..1481
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..1638
                     /gene="Ctu2"
                     /gene_synonym="Ncs2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccagcccct ccatgtgtca ggccggtgag gattacgcgg gaccggcgca gcgggagcct
       61 ccgcccgtgc cgcggccgag ccgggagcag aaatgtgtga agtgcgcaga aggcctaccg
      121 gtggtggtga tacgagcggg agatgccttc tgcagggatt gtttcaaggc attctatgtc
      181 cacaagttca gagccatgct tgggaagaac cgagtcatct ttcccggcga gaaggtgctc
      241 ttgtcgtggt ctgggggtcc ttcgtctagc tccatggtct ggcaagtcct tgagggcctg
      301 agtcaggatt ctgcaaaacg gcttcgcttt gtgccaggag ttatctatgt tgatgagggg
      361 gcagcctgtg gccagagctt agaggacaga gtgaagacat tggctgaggt gaagcggatc
      421 ttagggaaca ctggtttccc atttcatgtg gttgccttgg aagaggtgtt cagcctgccg
      481 ccatcagtgc tgcgccgtgc ttcccaggag ccagcaggga cagaggaggc ctacaaggca
      541 gctgtggaca gcttcctgca gcagcaacat gtgctaggga cggaggcctg cgccagcccg
      601 gctcagggac agggtcagct gcgtccatcc cacagccagg aaccctcagg cacggttggg
      661 caccccaaag atgctcagac tgaggccttg tctaggttgt tcaagtccat aaagacactc
      721 acagccaaag aggagcttct gcagacccta aggacccatc tgactgtgca cgtggcccga
      781 agccatggct accgcaaggt gatgacaggg gagagctgca cccgtttggc catcaagctt
      841 atgaccaacc tggccctggg gagaggcgcc ttcctcgctt gggacacggg cttctcagat
      901 gagcggcatg gggatgtggt attggtgagg cccatgcggg accacacgct gaaggaagtg
      961 gccttctaca accgcctgtt tggtgtcccc tctgtcttca caccagccat tgataccaag
     1021 gctccagaaa aggctagtat ccaccggctg atggaggcct ttatcttgaa gctgcagact
     1081 ctctttccct ctacggtcag caccgtgtac aggacaagtg agaagttggt caaagctccc
     1141 cgggagggct gtgccactgg cccctcaggc cccaactgcc tcctctgcat gtgtgcctta
     1201 gacgttgaca atgctgacag tgccacggcc tttggggctc agtcctcctc acatctctcc
     1261 cagatgctga ctgctgaggc tgggacgcct acccggccct gctgtggtgc aggggagggt
     1321 cagacccaga gctgccacag ggcagtcggc aggagggagg atgcatgggc ctgcatcata
     1381 gagcagttat gttacagctg ccgggtgaac atgaaggacc tgccctccct ggacccattg
     1441 ccaccctacg tcctgactga ggctcaactc cgcagccaga ggggctccgt ctctgaggaa
     1501 atccaggaat atctgattga ggaggaggaa gaggaagaca gagctgagcc atgtgaagcc
     1561 atgaagcaag aagctgagga caaagggatt gggctatgac cgtccatttg tataaataaa
     1621 aatgttttac ttagaaaaaa aaaaaaaaaa aaaaaaaaaa
//
