LOCUS       XM_017592494            5997 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus cortactin binding protein 2 (Cttnbp2),
            transcript variant X1, mRNA.
ACCESSION   XM_017592494
VERSION     XM_017592494.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017592494.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017592494.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5997
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5997
                     /gene="Cttnbp2"
                     /gene_synonym="Cbp90; Cortbp2"
                     /note="cortactin binding protein 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 15
                     ESTs, 1 Protein, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 32 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:282587"
                     /db_xref="RGD:628691"
     CDS             141..5096
                     /gene="Cttnbp2"
                     /gene_synonym="Cbp90; Cortbp2"
                     /codon_start=1
                     /product="cortactin-binding protein 2 isoform X1"
                     /protein_id="XP_017447983.1"
                     /db_xref="GeneID:282587"
                     /db_xref="RGD:628691"
                     /translation="MATDSASCEPDLSRAPGDAEGATAEAAKKEFDVDTLSKSELRML
                     LSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGAGDKEKPV
                     CTNPLSILEAVMAHCRKMQERMSAQLAAAESRQKKLEMEKLQLQALEQEHKKLAAHLE
                     EERGKNKHVVLMLVKECKQLSGKVVEEAQKLEEVMVKLEEEKKKTSELEDQLSAEKQR
                     SAGMEAQLEKQLFEFDTEREQLRAKLTREEAHTTDLKEEIDKMKKMMEQMKKGNDGKP
                     GLSLPRKTKDKRLASISVATEGPVTRSVACQTDVVTESTDPVKKLPLSVPIKPSTGSP
                     LVSTNTKGNVGPSALLIRPGIDRQASHSDLGPSPPTALPSSASRIEENGPSAGNAPDL
                     SNSTPSTPSGTAPAAAQTLGAAPQNHSQAPPVHSLHSPCANTHPGLNPRIQAARFRFQ
                     GNANDPDQNGNNTQSPPSRDVSPTSRDNLVAKQLARNTVTQALSRFTSPQAGASSRLG
                     ASPGGDAGTCPPVGRTGLKTPGAARVDRGNPPPIPPKKPGLSQTPSPPHPQLRASNAG
                     AKVDNKIVASPPSTLPQGTKVVNEENVPKSSSPQLPPKPSIDLTVASAGCPVSALATS
                     QVGAWPAETPGLNQPACTDSSLVIPTTVAFRSSINPVSASSRSPGASDSLLVTASGWS
                     PSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYCCEDSHSALYS
                     AAKNGHTDCVRLLLNAEARVDAADKNGFTPLCVAAAQGHFECIELLTAYNANINHSAA
                     GGQTPLYLACKTGNKECIKLLLEAGTDRSIKTRDGWTPIHAAVDTGNVDSLKLLMYHR
                     VPAPGNSLSAEEPKSGLFSLNGGESPPGSSKPVVPADLINHADKEGWTAAHIAASKGF
                     KNCLEILCRHGGLEPERRDKCNRTVHDVATDDCKHLLENLNALKIPLRISVGEIQPSN
                     DGSDDFECEHTICTLNIRKQTSWEDFSKAVSQALTNHFQAISSDGCWGLEDGTLNNTT
                     DSCIGLGTSSIQSIMLGSIPWSTGQSFSQSPWDFMKKKKVEQVTVLLSGPQEGCLSSV
                     TYTSMIPLQMLQNYLRLVEQYHNVIFHGPEGSLQDYIANQLALCMKHRQMAAGFPCEI
                     VRAEVDSGFSKEQLVDVFISNACLIPVKQFPVKKKIIVILENLEKSSLSELLGDFLAP
                     LENRSTESPCTFQKGKGNGTSECYYFHENCFLLGTLAKACLQGSDLLVQQHFRWVQLR
                     WDCEPSQGLLQRFLRRKAVSKFRGQLPAPCDPVCKIVDWVISVWRQLNSCLARLGTPE
                     ALLGPKYFLSCPVVPGHAQATVKWMSKLWNAIIAPRVQEAILSRAAMNKQPGARQTAS
                     KKHPSQGQQAVVRAALSILLNKAILHGCPLPRTELDQQIADFKGGSFPLSIVSSYSKK
                     KGESAAWRKVNTSPRKKPGHFSSPMWNKPDLKHEGMRNKSVPHLNINRSSSLSKQQSL
                     ENDLSMTLTLDHRLSLGSDDEADLVKELQSMCSSKSESDISKIADSREDLRTFDSSRT
                     NPVTSAPVNLRMPVPQKEASPLSSHQTTECSNSKSKTELGVSRVKSFLPVPRSKVAQC
                     SQNTKRSSSSSSNTRQLEINNNSKEENWNVDKHEHVEKRNK"
ORIGIN      
        1 aaaggcggga ggggaccgcc gagctccggg gctgagagcg ccgcggccac agccagcagc
       61 gggttaagcg ccgcccgcgc cgagagagct gagccctgcc gccgctccga gctcgcattc
      121 ggatccgcta gagcaggaag atggcgacgg acagcgcgag ctgcgagccc gacttgtccc
      181 gcgccccggg cgacgcggag ggggccacgg cggaggcggc gaaaaaggag tttgatgtgg
      241 acaccctcag caaatcagag ctgcggatgc tcctcagtgt gatggaaggt gaactagaag
      301 ccagagacct cgtgattgag gccctgcggg ctcgcaggaa ggaggtgttc atccaggaac
      361 gttatgggag atttaatcta aacgaccctt tcctggcact ccagagagac tatgaagcgg
      421 gtgctggtga caaagagaag ccagtctgca ccaacccact ctccattctt gaagccgtca
      481 tggcccactg cagaaaaatg caagaaagaa tgtccgcaca gctggctgcc gctgagagta
      541 ggcagaaaaa gttggagatg gaaaagctcc agcttcaggc ccttgaacag gagcacaaga
      601 agctggctgc ccacctggag gaagagaggg gcaagaacaa gcacgtggtc ctgatgctgg
      661 tgaaggagtg caagcagctc tcaggcaaag tcgtagagga agctcagaag ctggaggaag
      721 tcatggtgaa attggaggag gaaaagaaaa agacaagtga gttagaagac cagctctccg
      781 ctgagaaaca gagaagcgct ggaatggaag ctcagctgga gaaacagctc tttgagtttg
      841 atacggaacg ggagcagctg cgggccaagc tgacccgaga agaagcacac accaccgacc
      901 tcaaagagga gatagacaag atgaagaaaa tgatggagca aatgaagaaa ggcaacgatg
      961 ggaagcccgg actctccctc ccccggaaga caaaagataa gcgactggct tccatatctg
     1021 tggcaacaga agggcctgtg acaaggtctg ttgcttgcca gacagatgta gtgacagaaa
     1081 gcactgaccc tgtgaagaaa ttgcctttgt ctgtacccat aaaaccttcc acagggagcc
     1141 ccctagtttc cacaaacaca aaagggaatg tgggccccag tgccctgctg attagaccag
     1201 gtattgatag acaagcttcc cacagtgact tgggtccctc tccacctact gccctaccgt
     1261 caagtgcaag tagaattgag gaaaacggac caagtgcagg caatgcccct gacctatcaa
     1321 acagcacacc ctcaactcct agtggaactg cccctgctgc tgctcagaca ctaggtgcag
     1381 caccccagaa ccattcacaa gctcctcctg tgcacagttt acattcaccg tgtgccaaca
     1441 ctcatccagg tctcaaccca cgcatccaag cagctagatt tagatttcag ggcaatgcaa
     1501 atgacccaga ccagaatgga aataacactc aaagtcctcc ctccagagat gtttctccta
     1561 cgagtcgtga caacctagta gccaagcagc tagctcggaa tactgtgacc caagcgctgt
     1621 ccagatttac cagccctcaa gcaggtgctt cttcaaggct gggagcatct ccaggaggcg
     1681 atgctggcac ctgccctcca gttggtcgaa ccggtttaaa gactccaggg gcagcacgag
     1741 ttgacagagg aaatcctcct cctatccctc ccaaaaagcc agggctctcc caaactcctt
     1801 ctccaccaca ccctcaactg agggcctcca atgcaggggc caaagttgat aacaaaattg
     1861 tggcttcacc tccctctaca ttgccacaag ggaccaaggt agtaaatgag gagaacgtcc
     1921 ctaagtcatc ctcccctcag ctgccaccaa aaccatccat agatttaact gtggcatctg
     1981 caggctgtcc cgtttcggcc ctggccacgt ctcaggtggg tgcctggcct gctgaaaccc
     2041 ctggactgaa ccaacccgca tgtacagaca gctcccttgt cattcccacc accgttgcct
     2101 ttcgctcttc cataaaccct gttagtgcct catcccgtag ccccggtgcc tcagacagcc
     2161 tcttggtaac agcatcaggc tggtcaccct ccctaacccc tttgctaatg agtggtggtc
     2221 ctgcccccct ggctggcagg cccacccttc ttcagcaagc tgctgcccag ggaaatgtca
     2281 ctctattatc aatgctgctt aatgaagaag gactggacat aaattactgc tgtgaagata
     2341 gccattctgc cttgtattct gctgctaaga atggacatac agactgtgtg cgattgctgc
     2401 tgaatgcaga agcccgcgtc gacgctgctg ataaaaatgg cttcacaccc ttgtgcgttg
     2461 cagccgctca gggacatttt gaatgtatag aattactaac tgcatacaat gccaacatta
     2521 atcactctgc tgctggagga cagacacctc tgtacctggc ctgtaaaact ggaaataagg
     2581 aatgtatcaa actcctgctg gaagctggca ctgaccggag tataaaaacc agagatggct
     2641 ggacaccaat tcatgcagcc gtggacactg gtaatgtgga cagcctcaag ctattgatgt
     2701 accatagagt gccagcccct ggaaactctt tgagtgcaga agagcccaag tcaggcttgt
     2761 tcagcttgaa tggaggtgag agccctccag gttcatctaa gcctgtggtt cctgcggacc
     2821 tcattaacca cgctgacaaa gaaggctgga ctgctgccca tattgctgct tccaaaggtt
     2881 tcaagaactg cctagaaatc ttgtgtaggc atggagggct agagccggaa aggagagaca
     2941 agtgcaatcg gactgtgcat gatgttgcca ctgatgactg caagcatttg ctggagaatc
     3001 tgaatgctct taaaataccc ttaaggattt ccgtgggtga aattcaacca agcaacgacg
     3061 gttctgacga ctttgaatgt gaacacacaa tatgcacttt aaatatccgc aaacagacat
     3121 catgggaaga tttttcaaaa gcagtgagtc aggctctgac aaatcacttc caagccatct
     3181 cttctgatgg atgttggggt ctggaagatg ggacacttaa taacacgact gactcctgca
     3241 tcggtcttgg caccagcagc atacaatcca tcatgctagg aagtattccg tggtcaactg
     3301 gtcagagctt ttcccagtcc ccgtgggact tcatgaagaa gaagaaggtg gagcaggtca
     3361 cagtgctctt gtcaggtccc caagaaggct gcctcagtag tgtgacttat acatccatga
     3421 tcccacttca gatgctgcag aactacctca ggctggttga gcaatatcat aatgtcattt
     3481 tccatggccc agaaggaagc ttgcaagact acatagcaaa tcagcttgcc ctctgcatga
     3541 agcacagaca gatggctgca ggattcccct gtgaaatagt gagagctgag gtggattcag
     3601 gtttctccaa ggaacagcta gtagacgtgt tcatcagtaa tgcctgtctg atcccagtaa
     3661 agcagttccc tgttaagaag aaaataatcg tcatcttgga aaatttggaa aaatcatcat
     3721 tgtctgagtt actgggggac tttttggcac ctttggagaa tcgcagcact gaaagcccat
     3781 gcactttcca gaaaggtaaa ggaaatggaa catctgaatg ctattatttc catgagaact
     3841 gctttctgct gggaaccctc gccaaggctt gtctccaggg ctctgacctg ctggtgcagc
     3901 aacacttccg ctgggttcag ctgcgctggg attgcgagcc cagtcaagga ctgcttcaga
     3961 ggttcctccg aagaaaagca gtcagcaagt tcagaggtca gctgcccgca ccctgtgatc
     4021 ctgtgtgtaa aattgtggac tgggttatct ctgtctggag gcagctcaac tcctgcctgg
     4081 cccgcttggg tacaccggaa gcacttcttg gacccaagta tttcctgtct tgtccagtag
     4141 tcccgggaca tgcccaagca acagtgaagt ggatgtctaa gctgtggaac gccatcattg
     4201 ctccccgagt tcaagaagca atactgtcaa gagccgccat gaacaaacaa cctggtgcta
     4261 ggcagacagc ttcgaagaag caccctagcc aagggcagca ggctgtggtg agggctgctc
     4321 tcagcattct gcttaataaa gccattctgc atggctgtcc ccttcccagg acagagctgg
     4381 accagcagat agcagacttc aaagggggaa gtttccctct gtcaatagtt tcaagttata
     4441 gcaagaagaa aggagagagt gcagcctgga gaaaggtgaa caccagtcct cgcaagaaac
     4501 ctgggcactt ctcctcaccc atgtggaaca agccagacct gaagcatgaa ggtatgagaa
     4561 acaagagtgt accacatctg aatattaaca ggagctcctc tctgtcaaag caacagtcct
     4621 tagagaatga tctatccatg acattgactt tggaccacag actctctttg ggttcagatg
     4681 atgaggcaga tctggtcaaa gaactccaga gtatgtgttc cagcaaatct gagtctgata
     4741 taagcaagat tgctgattcc agggaagact taaggacatt tgatagttca agaaccaacc
     4801 ctgtgacttc agcacctgtt aacctgagga tgccagtgcc acagaaggaa gccagtcctc
     4861 tcagcagcca tcaaactacc gaatgcagca acagtaaatc caagactgag ttgggtgtct
     4921 caagagttaa atcttttctt cctgttccta gaagtaaagt cgcccagtgt tcccagaaca
     4981 ccaaaagaag cagcagcagc agcagtaata caaggcaact agaaatcaat aacaactcca
     5041 aagaagagaa ttggaacgta gacaaacacg aacacgtaga aaaacgtaac aaataggcct
     5101 gcctacaaca cctccaacaa cgtgatcacc ttaacgtctt ttgtatattt catgcagaaa
     5161 caccaagaca aagaagatgt aaatacctta aaatgaataa aaccattttc ctgtaatata
     5221 aaggacaggt gcgggaccac tattcagcct tttgtaaaga atgtatttat aacctcacat
     5281 ttttttttct gttaatccta taggactaaa ctttgatccc atgaacttac agcaaccttt
     5341 caagtagttt ttttataata gaaacattgt aatcgtttta atggagatgt tcaggggtat
     5401 taaagcagaa gtgtctgtgt actgtatatt tctatctgta catatgtaca tatatgtata
     5461 ttgacagaag ttgcatacat gtgtacaaga ttggcttaga tgaaatgtgc cagtttgaat
     5521 ggagatgata attttatgct catctgatgg ggaatgactc gaatggggca ataacaaaac
     5581 atttctaaac agttattttc cattaaaagc catatgaagt attttgcctg ttaaaattct
     5641 agttttacat tttgaatctt ttagtggtta cattgccatc tggttgcatc atgtatatat
     5701 atttacgctt cttaatttgc attatgactt gtaaaaaata tgaaattata atgcaataaa
     5761 agtgttatct ttcttacaaa acttttgtac ctaagtggat ataaaagtta tctgcatcaa
     5821 gaaagacatc aattaaatga atttggagtt aacgccttca atatatttct aataacacac
     5881 cgataataaa attaatattt tctagaagtg tgtcttataa aggaatggtg aagttattta
     5941 tccaatttac ggttaaggta ctttgatgcc aaataaaatt ttgaactagt gaaatta
//
