LOCUS       NM_175581               1222 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cathepsin R (Ctsr), mRNA.
ACCESSION   NM_175581 XM_225130
VERSION     NM_175581.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1222)
  AUTHORS   Sol-Church,K., Frenck,J., Bertenshaw,G. and Mason,R.W.
  TITLE     Characterization of mouse cathepsin R, a new member of a family of
            placentally expressed cysteine proteases
  JOURNAL   Biochim Biophys Acta 1492 (2-3), 488-492 (2000)
   PUBMED   11004518
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097484.1.
            
            On Jul 17, 2005 this sequence version replaced NM_175581.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097484.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1222
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..1222
                     /gene="Ctsr"
                     /gene_synonym="Cts6"
                     /note="cathepsin R"
                     /db_xref="GeneID:290975"
                     /db_xref="RGD:631422"
     exon            1..66
                     /gene="Ctsr"
                     /gene_synonym="Cts6"
                     /inference="alignment:Splign:2.1.0"
     exon            67..202
                     /gene="Ctsr"
                     /gene_synonym="Cts6"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..1081
                     /gene="Ctsr"
                     /gene_synonym="Cts6"
                     /note="cathepsin 6"
                     /codon_start=1
                     /product="cathepsin R precursor"
                     /protein_id="NP_783171.2"
                     /db_xref="GeneID:290975"
                     /db_xref="RGD:631422"
                     /translation="MSSTFFLAILCLGVGSGALAFDPSLDAEWHDWKTEYEKSYTMEE
                     EGHRRAVWEENMKMIKLHNRENSLGKNGFIMEMNEFGDLTAEEFRKMMVNIPIRSHRK
                     GKIIRKRDVGNVLPKFVDWRKKGYVTRVQNQKFCNSCWAFAVTGAIEGQMFNKTGQLT
                     PLSVQNLVDCTKSQGNEGCQWGDPHIAYEYVLNNGGLEAEATYPYKGKEGVCRYNPKH
                     SKAEITGFVSLPESEDILMEAVATIGPISVAVDASFNSFGFYKKGLYDEPNCSNNTVN
                     HSVLVVGYGFEGNETDGNSYWLIKNSWGRKWGLRGYMKIPKDQNNFCAIASYAHYPTV
                     "
     exon            203..325
                     /gene="Ctsr"
                     /gene_synonym="Cts6"
                     /inference="alignment:Splign:2.1.0"
     exon            326..475
                     /gene="Ctsr"
                     /gene_synonym="Cts6"
                     /inference="alignment:Splign:2.1.0"
     exon            476..700
                     /gene="Ctsr"
                     /gene_synonym="Cts6"
                     /inference="alignment:Splign:2.1.0"
     exon            701..863
                     /gene="Ctsr"
                     /gene_synonym="Cts6"
                     /inference="alignment:Splign:2.1.0"
     exon            864..981
                     /gene="Ctsr"
                     /gene_synonym="Cts6"
                     /inference="alignment:Splign:2.1.0"
     exon            982..1196
                     /gene="Ctsr"
                     /gene_synonym="Cts6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaacctcag caatttctga agagttgact ctttgcaaca cactgaggca acagccatca
       61 ccaaaggtct tgaagaatga gttctacttt ctttttggcc atcctgtgtt taggagtagg
      121 ctcaggtgcc ctagcatttg atcccagttt ggatgctgaa tggcatgatt ggaagacaga
      181 atatgaaaaa tcatacacta tggaggaaga aggacatagg agagcagtat gggaagaaaa
      241 catgaaaatg atcaaactgc acaacaggga gaatagcctg gggaagaatg gcttcatcat
      301 ggaaatgaat gaatttggtg acctgactgc tgaagaattc cgaaaaatga tggtcaatat
      361 tccaatccgg agtcacagga agggaaaaat catcaggaag cgtgatgttg gtaatgttct
      421 accgaaattt gtggactgga gaaagaaagg ctacgtgact cgagtacaga atcagaaatt
      481 ctgtaattct tgttgggctt ttgctgtgac tggtgccata gaaggacaga tgttcaacaa
      541 aactggccaa ctcacccctc tgagtgtgca gaacctcgtg gactgtacta aatctcaagg
      601 aaatgaaggc tgtcaatggg gtgatccaca cattgcctat gagtatgttt tgaacaatgg
      661 cggtctggag gctgaggcaa cctatccata taaaggaaaa gaaggagtgt gcaggtacaa
      721 tccaaagcat tctaaggcgg aaatcacagg atttgtatct ctcccagaaa gtgaggatat
      781 tctaatggaa gctgtagcaa ccattgggcc catctctgtt gcagttgatg cttcatttaa
      841 cagcttcggt ttctacaaaa aaggtcttta tgatgagccg aattgcagca acaatactgt
      901 gaatcattca gtcctggtgg ttggctatgg atttgaggga aatgaaacag atggcaatag
      961 ctactggctg atcaagaaca gctggggtag aaaatggggc cttcgaggct acatgaagat
     1021 tcccaaagac cagaacaact tttgtgcaat tgcttcatat gcccattatc ccaccgtatg
     1081 aggagtctga tgtgcacggg gaagaatttg gcagaagaca gcattttcac agtaatgtta
     1141 ttcacttcaa tgtccagcct tctcttgctg tattaaagag ttgaatccta gaagaaaaaa
     1201 aaaaaaaaaa aaaaaaaaaa aa
//
