LOCUS       NM_139262               1319 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus cathepsin Q (Ctsq), mRNA.
ACCESSION   NM_139262
VERSION     NM_139262.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1319)
  AUTHORS   Sol-Church,K., Picerno,G.N., Stabley,D.L., Frenck,J., Xing,S.,
            Bertenshaw,G.P. and Mason,R.W.
  TITLE     Evolution of placentally expressed cathepsins
  JOURNAL   Biochem Biophys Res Commun 293 (1), 23-29 (2002)
   PUBMED   12054558
  REMARK    GeneRIF: shows evolution in placental expression by gene
            duplication
REFERENCE   2  (bases 1 to 1319)
  AUTHORS   Sol-Church,K., Frenck,J. and Mason,R.W.
  TITLE     Cathepsin Q, a novel lysosomal cysteine protease highly expressed
            in placenta
  JOURNAL   Biochem Biophys Res Commun 267 (3), 791-795 (2000)
   PUBMED   10673370
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On Dec 2, 2020 this sequence version replaced NM_139262.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF187323.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-57                JAXUCZ010000017.1  3633621-3633677
            58-143              JAXUCZ010000017.1  3633907-3633992
            144-277             JAXUCZ010000017.1  3634699-3634832
            278-400             JAXUCZ010000017.1  3635110-3635232
            401-580             JAXUCZ010000017.1  3635326-3635505
            581-805             JAXUCZ010000017.1  3636510-3636734
            806-968             JAXUCZ010000017.1  3637193-3637355
            969-1083            JAXUCZ010000017.1  3638033-3638147
            1084-1319           JAXUCZ010000017.1  3638945-3639180
FEATURES             Location/Qualifiers
     source          1..1319
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..1319
                     /gene="Ctsq"
                     /gene_synonym="CatQ"
                     /note="cathepsin Q"
                     /db_xref="GeneID:246147"
                     /db_xref="RGD:631421"
     exon            1..57
                     /gene="Ctsq"
                     /gene_synonym="CatQ"
                     /inference="alignment:Splign:2.1.0"
     exon            58..143
                     /gene="Ctsq"
                     /gene_synonym="CatQ"
                     /inference="alignment:Splign:2.1.0"
     exon            144..277
                     /gene="Ctsq"
                     /gene_synonym="CatQ"
                     /inference="alignment:Splign:2.1.0"
     CDS             152..1183
                     /gene="Ctsq"
                     /gene_synonym="CatQ"
                     /codon_start=1
                     /product="cathepsin Q precursor"
                     /protein_id="NP_640355.1"
                     /db_xref="GeneID:246147"
                     /db_xref="RGD:631421"
                     /translation="MTPAVFLVILCLGVVPGASALDLSLDVQWQEWKIKYEKLYSPEE
                     EVLKRVVWEENVKKIELHNRENSLGKNTYTMEINDFADMTDEEFKDMIIGFQLPVHNT
                     EKRLWKRALGSFFPNSWNWRDALPKFVDWRNEGYVTRVRKQGGCSSCWAFPVTGAIEG
                     QMFKKTGKLIPLSVQNLIDCSKPQGNRGCLWGNTYNAFQYVLHNGGLEAEATYPYERK
                     EGVCRYNPKNSSAKITGFVVLPESEDVLMDAVATKGPIATGVHVISSSFRFYQKGVYH
                     EPKCSSYVNHAVLVVGYGFEGNETDGNNYWLIKNSWGKRWGLRGYMKIAKDRNNHCAI
                     ASLAQYPTV"
     exon            278..400
                     /gene="Ctsq"
                     /gene_synonym="CatQ"
                     /inference="alignment:Splign:2.1.0"
     exon            401..580
                     /gene="Ctsq"
                     /gene_synonym="CatQ"
                     /inference="alignment:Splign:2.1.0"
     exon            581..805
                     /gene="Ctsq"
                     /gene_synonym="CatQ"
                     /inference="alignment:Splign:2.1.0"
     exon            806..968
                     /gene="Ctsq"
                     /gene_synonym="CatQ"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1083
                     /gene="Ctsq"
                     /gene_synonym="CatQ"
                     /inference="alignment:Splign:2.1.0"
     exon            1084..1319
                     /gene="Ctsq"
                     /gene_synonym="CatQ"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctctgaaga gttgaatcta caaagtgatc tgaggcagta gtggtcatta cataaagagt
       61 ttcagcctgg atattgaaca catctctcgc attaacccat agacatatca gttttcaatt
      121 tacagtggca gatgcagtag caggttgaga catgactcct gctgtcttcc tagtcatcct
      181 ctgcttggga gttgtgccag gtgcttcagc attggatctt agtttggatg ttcaatggca
      241 agagtggaag ataaaatatg aaaaattata cagcccggag gaagaagtcc tgaagagagt
      301 agtatgggaa gaaaatgtga aaaaaattga actgcacaac agagagaatt ccctggggaa
      361 gaatacctac accatggaaa taaatgactt tgctgacatg actgatgaag aattcaaaga
      421 catgataatt ggttttcaac tgccagttca caacacagaa aaacgactct ggaaacgtgc
      481 acttggtagc tttttcccta attcttggaa ttggcgggac gctttgccaa aatttgttga
      541 ttggcgaaat gaaggctatg tgacccgtgt gaggaaacag ggaggatgta gttcttgttg
      601 ggcttttcct gtgactggtg ccatagaagg acaaatgttc aagaaaacag gcaaactgat
      661 ccccctgagt gtacagaacc taattgactg ctctaaacct caaggcaata gaggatgtct
      721 ttggggtaat acatacaatg cattccagta tgttttgcac aatggaggtc tggaagctga
      781 ggcaacctat ccatatgaac gaaaagaagg agtatgccgg tataatccta agaattcatc
      841 ggctaaaatc acaggatttg tggttctccc agaaagtgaa gatgtcctaa tggatgctgt
      901 agcaactaaa ggtcccattg ctactggagt tcatgtcatt tccagtagtt ttagattcta
      961 ccagaaaggt gtttatcatg agccaaaatg cagcagttat gttaatcatg cagtgctggt
     1021 ggtgggctat ggatttgagg gaaatgaaac agatggcaat aactactggc tgatcaagaa
     1081 cagctggggt aaacgatggg gattaagagg atatatgaaa attgccaaag acaggaacaa
     1141 ccactgtgca attgcttcat tagcccagta ccctactgtg taagcaacct gctgtcccaa
     1201 gaaagcacgt ggcacgggac tccatttcca gaggagggaa atctactcca atgaattgtc
     1261 tttgatgagt atgttaaact cttgagtccc acaaaatctg cattaaaacg tgaattctg
//
