LOCUS       XM_039103732            3108 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus cathepsin O (Ctso), mRNA.
ACCESSION   XM_039103732
VERSION     XM_039103732.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051337.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 11, 2024 this sequence was replaced by
            NM_001427175.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3108
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3108
                     /gene="Ctso"
                     /note="cathepsin O; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 8 ESTs, 4 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 185 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:684529"
                     /db_xref="RGD:1589156"
     CDS             51..986
                     /gene="Ctso"
                     /codon_start=1
                     /product="cathepsin O"
                     /protein_id="XP_038959660.1"
                     /db_xref="GeneID:684529"
                     /db_xref="RGD:1589156"
                     /translation="MKPHAASLLLLCCCCLGRGVARTWPWSPQREAAALRESLNRHRY
                     LNSFPHDNSTAFYGVNQFSYLFPEEFKALYLGSKPAWAPRYPAKGQTPIPNVSLPLRF
                     DWRDKHVVNHVRNQKTCGGCWAFSVVSAVESAGAIQGKPLDYLSVQQVIDCSFNNYGC
                     RGGSPLGALSWLNETQLKLVADSQYPFKAENGLCRYFPPSQSGVSVKGFSAYDFSNQE
                     DEMARALLSFGPLVVIVDAVSWQDYLGGIIQHHCSSGEANHAVLITGFDKTGNTPYWM
                     VRNSWGNSWGVEGYAYVKMGGNVCGIADSVAAVFV"
ORIGIN      
        1 agaaaccgaa agagaaagcg ggctgggcgc agaggacctc gggcgccggg atgaagcctc
       61 acgcggccag ccttttgctg ctgtgttgct gctgtctcgg ccgcggggtc gcccggacct
      121 ggccttggag cccccagcgg gaggcggctg ccttgcggga aagccttaac agacaccgat
      181 acttgaactc tttccctcat gacaactcca ctgccttcta tggagtaaat cagttttctt
      241 acttgtttcc tgaagagttt aaagctttgt atttgggaag caaacctgcc tgggctccca
      301 gatacccagc aaaaggacag acacctatcc ccaatgtgtc tttgccattg agatttgact
      361 ggagggacaa gcatgttgta aatcacgtaa gaaaccaaaa gacgtgtgga ggatgctggg
      421 ccttcagcgt ggtcagtgca gtagagtcag ctggtgcgat ccaagggaaa cccctggatt
      481 acctgagcgt gcagcaagtc attgactgct cctttaataa ttatggctgc cgcggtggct
      541 ctcctctcgg tgccttgagc tggctaaatg agacacagtt gaagttggtg gcggattcac
      601 agtacccatt caaggcagaa aatggcctgt gtcgctactt ccctccatca caatctggag
      661 tttcagtcaa gggtttttct gcatatgact tcagtaacca agaagatgaa atggccagag
      721 ccctactgtc cttcggccct ttggttgtga tagttgatgc agtgagctgg caggattatc
      781 tggggggcat aatccagcat cactgctcca gtggggaggc aaaccacgcg gttctcatca
      841 caggctttga taaaacagga aatactccat attggatggt gcgaaactcc tggggaaact
      901 cctggggagt agaaggctat gcctacgtga aaatgggagg taatgtttgt ggcattgcag
      961 actctgttgc tgctgtcttc gtgtgatcat ggagtgtttt ggaatcctta tgagacaact
     1021 actaaaatga tgtgcttcag gtttcaacaa ctcatctaca gacagattct aagagaaaac
     1081 tggcattttg taaagcaaca taggacattc tatttttgcc aagagatgga cagccgaagt
     1141 tcctaggaaa tcccccagca cactgactga tcaacggaat ctgtgggaca gtccatacct
     1201 ctgagagttt ggtgggatca gaagtcacat agtatctggg agcagatggg atttttgctt
     1261 gcttattgtc tttctggcta tcctaatgaa gtactttggt caggttgagt caaagaagtg
     1321 atgagaatgt gttttccttt gtgacttaca atcaccagtt ttagattagc tcttctataa
     1381 gaactcccaa cctgatgtcg tgtgtacctc gcaattacag tggccttctg aaatggagtg
     1441 ccatgcgtcc agatttgaaa tatcagtggc ttcatctcgg caagtgaagc ttactctaga
     1501 cagtagaaca actatacaca aagaagaaat gggagaatcc catcttcaga gggccagccc
     1561 aactgaagtt aattgaagca catgacagct atgtgatagg gagtacccta cactacttcc
     1621 tggaagacat aatttctata aagcctcact atcaagcatc caaaactctt agcttcttgc
     1681 gttcttccct ctgtagtaga caacaaagca tgtcccacct ttattccctc ttggccttta
     1741 ccatacggtt tctatggttt cctggtggtt caccttccaa tctaactcag acccattgtt
     1801 gatattccat ttctgtggcc caatccctta tttttaaaaa ataagttctc tgacacccgc
     1861 tcacattgct ccttgtttat gtccttcatt agaatagcag cattgagaac aaaactcctt
     1921 actcttttgt ctgtaccagt gagaagcaat ctcaaacagt tgtgcagagc ctggagtgta
     1981 gagaaatggc agaagaaaca tttcttctta acattttgaa taaagtggtc taattaccgg
     2041 aggaatccag agcaaaattt agttcagcta tagtttttgt taatgacctt tagtatgcta
     2101 tcagcaactt ttttaatacc cagtttcaaa agcagaagaa gtttcaaatt ttcaaaatgg
     2161 ctgttatcct ctaactgttc tgaattgata gcatttatta aaaaaaacct acatttgatt
     2221 ttgaattaaa aagaaattgt tcttaaatat gtggtctata attgatcatt atttgtgagc
     2281 actaatagat atttattagt attgattagt tttatattca cattttcttg tatttgaacc
     2341 catatatcca gtgtggtttt ctccataatg cttctaaccc caccatgtcc aagattccca
     2401 tcaccatcct cccatatcta ttatcaatgc ccagtggtcc tttcctcctt accatttctt
     2461 tctgtcagca gcatgggcta ttgtgtaagc aggctataga gtcaaaagga agtctaggca
     2521 ctcaatctag ttgactcctc cttggaaccc actcctacat ctatctatat tctctctttt
     2581 ttgggatgta cacttttttt tcagagctgg ggaccaaacc cagggccttg cgcttgctag
     2641 gcaagcgctc taccactgag ctaaatcccc aacccccagg atgtacactt tttattagca
     2701 cctatctaca ctcttccgtt gactccagcc catctaaaat atcaaactaa ggcagattat
     2761 gtagagataa tgagtttatt attccacagt ttatgctgct ggagatctat atgagtgtgt
     2821 ctcagaggta aagggagatg agggatttta ctggtaaaac tgagatcatt aaactgttct
     2881 gttatgaaat gactacctag aactcagaga tctacatcaa gcttgactag gtagtcacca
     2941 ggcagatatt tttataaagt ttgctttggt tttttgtttt tgtttttgtt tttgttttga
     3001 tttgtatgaa gttatgatga cctttgatgc aatgtacttc aaacactttt tgtgatagtt
     3061 cttgttatgt atcatctata tataataccc acttttggtg acttgcca
//
