LOCUS       NM_181378               1351 bp    mRNA    linear   ROD 08-APR-2024
DEFINITION  Rattus norvegicus cathepsin M (Ctsm), mRNA.
ACCESSION   NM_181378
VERSION     NM_181378.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1351)
  AUTHORS   Sol-Church,K., Frenck,J. and Mason,R.W.
  TITLE     Mouse cathepsin M, a placenta-specific lysosomal cysteine protease
            related to cathepsins L and P
  JOURNAL   Biochim Biophys Acta 1491 (1-3), 289-294 (2000)
   PUBMED   10760593
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On Nov 27, 2020 this sequence version replaced NM_181378.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF456462.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                JAXUCZ010000017.1  3242488-3242551
            65-192              JAXUCZ010000017.1  3243825-3243952
            193-315             JAXUCZ010000017.1  3244255-3244377
            316-462             JAXUCZ010000017.1  3244470-3244616
            463-687             JAXUCZ010000017.1  3245034-3245258
            688-850             JAXUCZ010000017.1  3245620-3245782
            851-968             JAXUCZ010000017.1  3246372-3246489
            969-1351            JAXUCZ010000017.1  3247514-3247896
FEATURES             Location/Qualifiers
     source          1..1351
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..1351
                     /gene="Ctsm"
                     /note="cathepsin M"
                     /db_xref="GeneID:306720"
                     /db_xref="RGD:631420"
     exon            1..64
                     /gene="Ctsm"
                     /inference="alignment:Splign:2.1.0"
     exon            65..192
                     /gene="Ctsm"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..1068
                     /gene="Ctsm"
                     /codon_start=1
                     /product="cathepsin M precursor"
                     /protein_id="NP_852043.2"
                     /db_xref="GeneID:306720"
                     /db_xref="RGD:631420"
                     /translation="MTPAVFLAILCLRLISSSPAPDPVLDAEWQKWKIKYEKTYSLEE
                     EGQKRAVWEENMKKIKLHNGENGLGKHGFTMEMNAFGDMTIEEFRKLMIEIPIPTVKK
                     ENSVQKRQAVNVPNFINWRKRGYVTPVRRQGRCNVCWAFSVAGAIEGQMFQKTGQLIP
                     LSVQNLVDCSRPQGNLGCYLGNTYLALQYVKENGGLESEATYPYEEKEGSCRYHPDNS
                     TASITDFEFVPKNEDALMNAVATLGPISVAIDARHESFLFYRNGIYHEPNCSSSVVTH
                     AMLLVGYGFVGEESDGRKYWILKNSMGNKWGNRGYMKIAKDQGNHCGIATYALYPRV"
     exon            193..315
                     /gene="Ctsm"
                     /inference="alignment:Splign:2.1.0"
     exon            316..462
                     /gene="Ctsm"
                     /inference="alignment:Splign:2.1.0"
     exon            463..687
                     /gene="Ctsm"
                     /inference="alignment:Splign:2.1.0"
     exon            688..850
                     /gene="Ctsm"
                     /inference="alignment:Splign:2.1.0"
     exon            851..968
                     /gene="Ctsm"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1351
                     /gene="Ctsm"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtacaccag ggcagctgca gtcaccacag gtgaggtcct acatccacaa gggcagaaaa
       61 gtaaatatga ctcctgctgt ctttctggcc atcctgtgct tgagactgat ctcatcttca
      121 ccagcacctg atcccgtttt ggatgctgaa tggcagaaat ggaaaataaa atatgaaaaa
      181 acatacagcc tggaggaaga aggacagaag agagcagtat gggaagaaaa tatgaaaaag
      241 atcaaactgc acaatgggga gaatggccta gggaagcatg gtttcactat ggaaatgaat
      301 gcttttggtg acatgacaat tgaagaattc aggaaattaa tgattgaaat cccaatccca
      361 actgtcaaga aagagaacag tgtacagaaa cgtcaggctg ttaacgtgcc caactttata
      421 aactggagga agagaggcta tgttacccct gtgcggagac agggaagatg taatgtttgt
      481 tgggcttttt ctgtggctgg tgccatagaa ggacagatgt tccagaaaac aggtcaactg
      541 atccctctga gtgtacagaa cctggtggac tgctctagac ctcaaggcaa cctgggctgt
      601 tatttaggca atacatacct tgcattgcag tatgtgaagg aaaatggagg tctggaatct
      661 gaggcaacct atccatatga agaaaaggaa ggatcctgca ggtaccatcc agataattct
      721 actgctagta tcacagactt tgagtttgtc ccaaagaatg aggatgcatt aatgaatgct
      781 gtggcgacgc tagggcccat ttctgttgcg attgatgcaa ggcatgaatc tttcctgttc
      841 tatagaaatg gtatatatca tgagccaaac tgcagtagtt ctgttgtcac acatgctatg
      901 ttactggttg gctatggatt tgtaggagaa gaatcagatg gcaggaagta ctggattctt
      961 aagaacagca tgggaaataa atggggcaac agaggctata tgaagattgc caaagaccag
     1021 ggtaaccact gtggaattgc tacatatgcc ctttatccaa gggtgtgaat tgcctggtgg
     1081 tgacaaggaa ggaaagaaca gaagacaaca tgtagagaag aggcacttcc atttccaatc
     1141 agctggccat tcctgtgtat gtaagacact gcagtcattg gaaggccagt tgtgaggtga
     1201 atgttgtgat atgtttacta ttgtaagaca tgaccactgc tgtacctgat gccatacatt
     1261 ggtttgtatt tgttttctat aacagtgtta tttttatttt tcgtgtaaga aattaaatct
     1321 ttaaaaataa agctttcttt aaatgttgct c
//
