LOCUS       NM_017121               1283 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cathepsin J (Ctsj), mRNA.
ACCESSION   NM_017121
VERSION     NM_017121.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1283)
  AUTHORS   Hassanein,M., Bojja,A.S., Glazewski,L., Lu,G. and Mason,R.W.
  TITLE     Protein processing by the placental protease, cathepsin P
  JOURNAL   Mol Hum Reprod 15 (7), 433-442 (2009)
   PUBMED   19346238
  REMARK    GeneRIF: Results indicate a potential role of cathepsin P in
            processing and secretion of calreticulin during differentiation of
            trophoblast giant cells.
REFERENCE   2  (bases 1 to 1283)
  AUTHORS   Hassanein,M., Korant,B.D., Lu,G. and Mason,R.W.
  TITLE     Expression of cathepsin P mRNA, protein and activity in the rat
            choriocarcinoma cell line, Rcho-1, during giant cell transformation
  JOURNAL   Placenta 28 (8-9), 912-919 (2007)
   PUBMED   17218008
REFERENCE   3  (bases 1 to 1283)
  AUTHORS   Conliffe,P.R., Ogilvie,S., Simmen,R.C., Michel,F.J., Saunders,P.
            and Shiverick,K.T.
  TITLE     Cloning and expression of a rat placental cDNA encoding a novel
            cathepsin L-related protein
  JOURNAL   Mol Reprod Dev 40 (2), 146-156 (1995)
   PUBMED   7766407
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On Nov 27, 2020 this sequence version replaced NM_017121.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF310623.2, BC097263.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-71                JAXUCZ010000017.1  3744340-3744410
            72-208              JAXUCZ010000017.1  3744658-3744794
            209-331             JAXUCZ010000017.1  3745121-3745243
            332-478             JAXUCZ010000017.1  3745392-3745538
            479-703             JAXUCZ010000017.1  3745995-3746219
            704-866             JAXUCZ010000017.1  3746670-3746832
            867-984             JAXUCZ010000017.1  3747802-3747919
            985-1283            JAXUCZ010000017.1  3748690-3748988
FEATURES             Location/Qualifiers
     source          1..1283
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..1283
                     /gene="Ctsj"
                     /gene_synonym="Ctsp"
                     /note="cathepsin J"
                     /db_xref="GeneID:29174"
                     /db_xref="RGD:69241"
     exon            1..71
                     /gene="Ctsj"
                     /gene_synonym="Ctsp"
                     /inference="alignment:Splign:2.1.0"
     exon            72..208
                     /gene="Ctsj"
                     /gene_synonym="Ctsp"
                     /inference="alignment:Splign:2.1.0"
     CDS             83..1087
                     /gene="Ctsj"
                     /gene_synonym="Ctsp"
                     /note="catlrp-p; cathepsin L-related protein; cathepsin P"
                     /codon_start=1
                     /product="cathepsin J precursor"
                     /protein_id="NP_058817.1"
                     /db_xref="GeneID:29174"
                     /db_xref="RGD:69241"
                     /translation="MTPAVFLVILCFGVASGAPARDPNLDAEWQDWKTKYAKSYSPVE
                     EELKRAVWEENLKMIQLHNKENGLGKNGFTMEMNAFADTTGEEFRKSLSDILIPAAVT
                     NPSAQKQVSIGLPNFKDWRKEGYVTPVRNQGKCGSCWAFAAVGAIEGQMFSKTGNLTP
                     LSVQNLLDCSKSEGNNGCRWGTAHQAFNYVLKNKGLEAEATYPYEGKDGPCRYHSENA
                     SANITGFVNLPPNELYLWVAVASIGPVSAAIDASHDSFRFYSGGVYHEPNCSSYVVNH
                     AVLVVGYGFEGNETDGNNYWLIKNSWGEEWGINGFMKIAKDRNNHCGIASQASFPDIF
                     "
     exon            209..331
                     /gene="Ctsj"
                     /gene_synonym="Ctsp"
                     /inference="alignment:Splign:2.1.0"
     exon            332..478
                     /gene="Ctsj"
                     /gene_synonym="Ctsp"
                     /inference="alignment:Splign:2.1.0"
     exon            479..703
                     /gene="Ctsj"
                     /gene_synonym="Ctsp"
                     /inference="alignment:Splign:2.1.0"
     exon            704..866
                     /gene="Ctsj"
                     /gene_synonym="Ctsp"
                     /inference="alignment:Splign:2.1.0"
     exon            867..984
                     /gene="Ctsj"
                     /gene_synonym="Ctsp"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1283
                     /gene="Ctsj"
                     /gene_synonym="Ctsp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agatctcagg accacagcaa cctctgaaga gttgagtctg tggaggacca agacagcatc
       61 agtcaccaca ggttcttaag acatgacgcc tgctgtcttt ctggtgatcc tgtgctttgg
      121 agtggcctca ggtgccccag cacgtgatcc caatttggat gctgaatggc aagactggaa
      181 gactaaatat gcaaaatcat atagcccggt ggaagaagaa ctgaagaggg cagtatggga
      241 agaaaacttg aaaatgatcc aactgcacaa caaggagaat ggcctgggga agaatggctt
      301 cactatggaa atgaatgcct ttgctgatac aactggtgaa gaattcagaa aatcattgag
      361 tgatattcta attccggctg ctgtgacaaa cccaagtgcc cagaaacaag tctctattgg
      421 tttacccaac tttaaggatt ggagaaagga aggctatgtg actcctgtac ggaatcaggg
      481 taaatgcggc tcttgttggg cttttgctgc agttggtgcg atagaaggtc agatgttctc
      541 aaaaactggc aacctcaccc ctctaagtgt gcagaatcta ttggactgtt ctaaaagtga
      601 aggaaataat ggctgccgtt ggggtactgc acaccaagca ttcaattatg ttttgaaaaa
      661 taaaggtctt gaggctgagg caacctatcc atatgaagga aaagacggac cctgcaggta
      721 ccacagtgag aacgctagtg ctaacatcac aggttttgtg aacctcccac cgaatgagct
      781 ttacctatgg gttgctgtag catctattgg gcccgtctct gcggcaattg atgcttctca
      841 tgactctttc agattctaca gtggaggtgt ttatcatgag ccaaattgca gcagttatgt
      901 tgtgaatcat gcagtgctgg tggttggcta tggatttgag ggaaatgaaa cagatggcaa
      961 taactactgg ctgatcaaga acagttgggg tgaagaatgg ggcattaatg gcttcatgaa
     1021 gatagccaaa gatcgcaaca accactgtgg aattgcttca caagccagct tccccgatat
     1081 attctgagct gcctgttggt caccacagga ggacatggtg gagacagcat ttagtgcctt
     1141 ccacttcaca gtaaccagtc tctcctgagt gctttcaaca gttgagtagc taaaaagcta
     1201 ccttgtggtg tggaatctgg aacccacttg ttctacaaca gcatggcaac tactgtaata
     1261 aaattctgta ctgatgtgtc ttc
//
