LOCUS       NM_001034110            1922 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus cathepsin F (Ctsf), mRNA.
ACCESSION   NM_001034110
VERSION     NM_001034110.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1922)
  AUTHORS   Chiasserini D, van Weering JR, Piersma SR, Pham TV, Malekzadeh A,
            Teunissen CE, de Wit H and Jimenez CR.
  TITLE     Proteomic analysis of cerebrospinal fluid extracellular vesicles: a
            comprehensive dataset
  JOURNAL   J Proteomics 106, 191-204 (2014)
   PUBMED   24769233
REFERENCE   2  (bases 1 to 1922)
  AUTHORS   Maubach G, Lim MC and Zhuo L.
  TITLE     Nuclear cathepsin F regulates activation markers in rat hepatic
            stellate cells
  JOURNAL   Mol Biol Cell 19 (10), 4238-4248 (2008)
   PUBMED   18667530
  REMARK    GeneRIF: nuclear cathepsin F regulates activation markers in rat
            hepatic stellate cells
REFERENCE   3  (bases 1 to 1922)
  AUTHORS   Kang D, Oh S, Ahn SM, Lee BH and Moon MH.
  TITLE     Proteomic analysis of exosomes from human neural stem cells by flow
            field-flow fractionation and nanoflow liquid chromatography-tandem
            mass spectrometry
  JOURNAL   J Proteome Res 7 (8), 3475-3480 (2008)
   PUBMED   18570454
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC099780.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099780.1, EU253481.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1922
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1922
                     /gene="Ctsf"
                     /note="cathepsin F"
                     /db_xref="GeneID:361704"
                     /db_xref="RGD:1308181"
     exon            1..250
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..1420
                     /gene="Ctsf"
                     /EC_number="3.4.22.41"
                     /codon_start=1
                     /product="cathepsin F precursor"
                     /protein_id="NP_001029282.1"
                     /db_xref="GeneID:361704"
                     /db_xref="RGD:1308181"
                     /translation="MALLLQLLWLLTLIATVVLSPVPAKPWADDEQAWSLSSQELLAP
                     ARFALDMYNYGRTAVTRAVLGAVHGRVRRAGRGSLFSLEATLEEPPCNDPLVCLHPET
                     KKTMLCSFEVLEELKEHLLLRKDCSPVNAKVTESGNETFRAFLPMLDKDPLPQDFSVK
                     MATLFKDFMTTYNRTYESREEAQWRLTVFARNMIRAQKIQALDRGTAQYGITKFSDLT
                     EEEFHTIYLNPLLQKESGGKMSLAKSINDLAPPEWDWRKKGAVTEVKDQGMCGSCWAF
                     SVTGNVEGQWFLNRGTLLSLSEQELLDCDKMDKACMGGLPSNAYTAIKNLGGLETEDD
                     YGYQGHVQACNFSTQMAKVYINDSVELSRDENKIAAWLAQKGPISVAINAFGMQFYRH
                     GIAHPFRPLCSPWFIDHAVLLVGYGNRSNIPYWAIKNSWGRDWGEEGYYYLYRGSGAC
                     GVNTMASSAVVN"
     exon            251..349
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
     exon            350..434
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
     exon            435..496
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
     exon            497..572
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
     exon            573..686
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
     exon            687..832
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
     exon            833..929
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1010
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1130
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1195
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
     exon            1196..1286
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1345
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
     exon            1346..1863
                     /gene="Ctsf"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgaatcggg gcgagcagct tcgacctcgc tatggcgctc ctgctgcagc ttttgtggct
       61 gttgacgctg atcgcgaccg tggtcctgag cccagtccct gccaagccct gggcggatga
      121 cgagcaagcc tggagcctgt cctcccagga gctgctggcg cccgcccgct tcgcgctgga
      181 catgtacaat tacggccgta ctgcggtgac aagggccgtg ctaggggcgg tacacgggcg
      241 cgtccggcgg gccggccggg gctctctgtt ctccctggaa gccacattag aggagccacc
      301 ttgcaatgat cccctggtgt gcctgcaccc tgagacgaag aaaacaatgc tctgcagttt
      361 tgaagtcctg gaagagctaa aagaacactt gctgctgagg aaggactgta gcccagtgaa
      421 tgccaaggtt acagagtctg ggaacgagac cttccgagca ttccttccaa tgttggacaa
      481 ggatcccctg ccccaggact tttctgtgaa gatggctaca ctcttcaagg acttcatgac
      541 tacctataac cggacttacg aatcaaggga agaagcccag tggcgcttga ctgtctttgc
      601 cagaaatatg atacgagcgc agaagattca ggccctggac cgtggcacag ctcagtatgg
      661 gatcaccaag ttcagtgacc tcacagagga agagttccac accatctacc tgaatcccct
      721 cttacaaaag gagtctggcg ggaagatgag tctagccaag tccataaatg atctcgcccc
      781 acctgaatgg gactggagga agaaaggggc tgtcactgaa gtgaaggacc agggcatgtg
      841 tggctcctgc tgggccttct ctgtcacagg caacgtggag ggccagtggt tcctgaaccg
      901 ggggactctg ctctccctgt cagagcagga gcttttggat tgtgacaaga tggacaaggc
      961 ctgcatgggt ggactgccct ccaacgccta cacagccata aagaatttgg gagggctgga
     1021 gacagaggat gactatggct accagggcca cgttcaagcc tgtaacttct caacacagat
     1081 ggcaaaagtc tacatcaacg attcagtgga gctgagccgg gatgagaaca agatagcagc
     1141 ctggctggcc cagaaaggac cgatctcagt tgccattaat gccttcggca tgcagttcta
     1201 tcgccatggg attgctcacc cattccggcc cctctgcagc ccttggttca tcgaccacgc
     1261 tgtgttgctg gtgggctatg gaaaccgctc caacattcct tactgggcca tcaagaacag
     1321 ctggggcagg gactggggtg aggagggtta ctactactta tatcgtgggt ccggggcctg
     1381 tggtgtgaat accatggcca gttcggcagt ggtgaactga gagacttgct ggcctaggac
     1441 ctgacattga ccacagtggc cccttcctta gcctgactca tgctcgggcc cctcctcaga
     1501 agacagacgg ctgaggaaca ggcactttgt acctcagggt gagcagcggg ccctgcgccc
     1561 tttcttccct ccttctcatg cttacctgaa gttctccagc tgcatctttg ttggactatg
     1621 gtagctagga ggatcctgag gtgaaggagg ctttcccgga agccaacact agggcaagaa
     1681 ccttgggcta caatatgata caggatgaaa gtctgctcgt cacgaaacta gatttgtcct
     1741 cagcaggctc tgtctttctg ctttggtgtt cgtcagcctg atgctgtaca tcttctggtc
     1801 cctttccaca tccaggaaag ttgtaaccag ccttccctaa gagcaataaa aaggtagcct
     1861 gctaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1921 aa
//
