LOCUS       NM_054009                798 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus chymotrypsin-like (Ctrl), mRNA.
ACCESSION   NM_054009
VERSION     NM_054009.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 798)
  AUTHORS   Sogame,Y., Kataoka,K., Kato,M., Sakagami,J., Osawa,S., Takatera,A.,
            Mitsuyoshi,M., Usui,N., Mitsui,S. and Yamaguchi,N.
  TITLE     Molecular cloning and characterization of chymopasin, a novel
            serine protease from rat pancreas
  JOURNAL   Pancreas 25 (4), 378-386 (2002)
   PUBMED   12409833
  REMARK    GeneRIF: molecular cloning and characterization of chymopasin from
            the pancreas [chymopasin]
REFERENCE   2  (bases 1 to 798)
  AUTHORS   Reseland,J.E., Larsen,F., Solheim,J., Eriksen,J.A., Hanssen,L.E.
            and Prydz,H.
  TITLE     A novel human chymotrypsin-like digestive enzyme
  JOURNAL   J Biol Chem 272 (12), 8099-8104 (1997)
   PUBMED   9065485
REFERENCE   3  (bases 1 to 798)
  AUTHORS   von Deimling,O.H., Groning,J. and Gaa,A.
  TITLE     Genetic and biochemical characterization of a new chymotrypsin
            isozyme of the house mouse, CTRA-1
  JOURNAL   Biochem Genet 29 (11-12), 545-557 (1991)
   PUBMED   1820020
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB020757.1.
            
            [WARNING] On Oct 16, 2024 this sequence was replaced by
            NM_054009.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB020757.1, CF249047.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMN06621351
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..798
                     /gene="Ctrl"
                     /note="chymotrypsin-like"
                     /db_xref="GeneID:117184"
                     /db_xref="RGD:621501"
     exon            1..55
                     /gene="Ctrl"
                     /inference="alignment:Splign:2.1.0"
     CDS             4..798
                     /gene="Ctrl"
                     /EC_number="3.4.21.-"
                     /note="chymotrypsin-like protease CTRL-1; chymopasin"
                     /codon_start=1
                     /product="chymotrypsin-like protease CTRL-1 precursor"
                     /protein_id="NP_446461.1"
                     /db_xref="GeneID:117184"
                     /db_xref="RGD:621501"
                     /translation="MLLLSLTLSLVLLGSSWGCGVPAITPALSYNQRIVNGENAVPGS
                     WPWQVSLQDNTGFHFCGGSLIAPNWVVTAAHCKVTPGRHFVILGEYDRSSNAEPIQVL
                     SISKAITHPSWNPNTMNNDLTLLKLASPARYTAQVSPVCLASSNEALPAGLTCVTTGW
                     GRISGVGNVTPARLQQVVLPLVTVNQCRQYWGSRITDSMICAGGAGASSCQGDSGGPL
                     VCQKGNTWVLIGIVSWGTENCNVQAPAMYTRVSKFNTWINQVIAYN"
     exon            56..159
                     /gene="Ctrl"
                     /inference="alignment:Splign:2.1.0"
     exon            160..239
                     /gene="Ctrl"
                     /inference="alignment:Splign:2.1.0"
     exon            240..321
                     /gene="Ctrl"
                     /inference="alignment:Splign:2.1.0"
     exon            322..502
                     /gene="Ctrl"
                     /inference="alignment:Splign:2.1.0"
     exon            503..636
                     /gene="Ctrl"
                     /inference="alignment:Splign:2.1.0"
     exon            637..798
                     /gene="Ctrl"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acgatgttac tgctcagcct aacccttagc ctggtccttc ttggctcctc ctggggctgt
       61 ggtgttcccg ccatcacacc tgcactgagc tacaaccaga ggattgtcaa cggggagaat
      121 gcagtgccag gctcctggcc ctggcaagtg tctctgcagg ataacaccgg cttccacttc
      181 tgtggtggtt ctctcattgc cccaaactgg gtggtcacgg ctgcccactg caaagtcacg
      241 cctggacgcc actttgtcat tttaggagaa tatgaccgat cttccaatgc tgagcctata
      301 caggtgctct ccatctcgaa ggcgatcaca caccctagct ggaaccccaa cactatgaac
      361 aatgacctga ctcttctgaa gcttgcctca ccagcccggt acacagcaca agtctcacca
      421 gtctgcctgg cttcctcaaa tgaggcactt cctgcaggcc tcacatgcgt caccactggc
      481 tggggccgca tcagtggtgt gggcaacgtg acaccagcac gtctgcagca agtagttcta
      541 cccctggtca ctgtgaatca gtgtcggcag tattggggtt cacgcattac tgactccatg
      601 atatgtgcag gtggcgcagg tgcctcctca tgtcagggtg actcaggagg ccctcttgtc
      661 tgccagaagg gaaacacctg ggtgcttatt ggtattgtct cctggggcac tgagaactgc
      721 aatgtacaag caccggccat gtacactcgg gtcagcaagt tcaacacctg gatcaaccaa
      781 gtcatagcct acaactaa
//
