LOCUS       NM_001409574            6308 bp    mRNA    linear   ROD 24-SEP-2023
DEFINITION  Rattus norvegicus CTD small phosphatase like 2 (Ctdspl2),
            transcript variant 2, mRNA.
ACCESSION   NM_001409574 XM_039104969
VERSION     NM_001409574.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6308)
  AUTHORS   Wani S, Sugita A, Ohkuma Y and Hirose Y.
  TITLE     Human SCP4 is a chromatin-associated CTD phosphatase and exhibits
            the dynamic translocation during erythroid differentiation
  JOURNAL   J Biochem 160 (2), 111-120 (2016)
   PUBMED   26920047
REFERENCE   2  (bases 1 to 6308)
  AUTHORS   Zhao Y, Xiao M, Sun B, Zhang Z, Shen T, Duan X, Yu PB, Feng XH and
            Lin X.
  TITLE     C-terminal domain (CTD) small phosphatase-like 2 modulates the
            canonical bone morphogenetic protein (BMP) signaling and
            mesenchymal differentiation via Smad dephosphorylation
  JOURNAL   J Biol Chem 289 (38), 26441-26450 (2014)
   PUBMED   25100727
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000118.1.
            
            [WARNING] On Mar 19, 2024 this sequence was replaced by
            NM_001409574.3.
            
            On Nov 25, 2022 this sequence version replaced NM_001409574.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR8487231.163533.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132265
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-145               JACYVU010000118.1  32782328-32782472
            146-355             JACYVU010000118.1  32794391-32794600
            356-494             JACYVU010000118.1  32802316-32802454
            495-644             JACYVU010000118.1  32803409-32803558
            645-857             JACYVU010000118.1  32805271-32805483
            858-936             JACYVU010000118.1  32809731-32809809
            937-1048            JACYVU010000118.1  32812477-32812588
            1049-1135           JACYVU010000118.1  32816342-32816428
            1136-1198           JACYVU010000118.1  32826165-32826227
            1199-1278           JACYVU010000118.1  32826331-32826410
            1279-1405           JACYVU010000118.1  32829265-32829391
            1406-1501           JACYVU010000118.1  32830824-32830919
            1502-6308           JACYVU010000118.1  32832879-32837685
FEATURES             Location/Qualifiers
     source          1..6308
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q35"
     gene            1..6308
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /note="CTD small phosphatase like 2"
                     /db_xref="GeneID:311368"
                     /db_xref="RGD:1309219"
     exon            1..145
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /inference="alignment:Splign:2.1.0"
     exon            146..355
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /inference="alignment:Splign:2.1.0"
     CDS             170..1567
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /EC_number="3.1.3.-"
                     /note="CTDSP-like 2; CTD (carboxy-terminal domain, RNA
                     polymerase II, polypeptide A) small phosphatase like 2"
                     /codon_start=1
                     /product="CTD small phosphatase-like protein 2"
                     /protein_id="NP_001396503.1"
                     /db_xref="GeneID:311368"
                     /db_xref="RGD:1309219"
                     /translation="MKLRTRKASQQSSPIQTQRTARAKRKYSEVDDSLPSGGEKPSKN
                     ETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTPRTGEKPDKQLSRVRR
                     KSPVNGEAGSYEMTNQHIKQNGKLEDNPCSGSPPRTTLLGTIFSPVFNFFSPANKNGT
                     SGSDSPGQAVEAEEIVKQLDMEQVDEITTSTTSANGAAYSNQAVQVRPSLNNGLEEAE
                     ETVTRDIPPLTAPVAPESGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPA
                     LPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREF
                     LERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNIL
                     GRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRP
                     HIRDRFRLHDLLPPD"
     exon            356..494
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /inference="alignment:Splign:2.1.0"
     exon            495..644
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /inference="alignment:Splign:2.1.0"
     exon            645..857
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /inference="alignment:Splign:2.1.0"
     exon            858..936
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1048
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1135
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1198
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1278
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /inference="alignment:Splign:2.1.0"
     exon            1279..1405
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..1501
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /inference="alignment:Splign:2.1.0"
     exon            1502..6308
                     /gene="Ctdspl2"
                     /gene_synonym="RGD1309219"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagcaggtc ggtaggcggg aaatggcgac tggctgaagg agctggttct gttgctgctg
       61 agggataagc gggaaagaca ccacctattg cgcagttggg accatcgccg gagcccgagg
      121 acacttttct gtcgtcacag tgaaggttta catgtggcaa cccataaaga tgaagctgag
      181 aacacggaag gcttctcagc agtccagtcc aatccaaaca cagcgcactg ccagagcaaa
      241 aaggaaatac tcagaggttg atgatagctt gccttcagga ggagaaaaac catccaagaa
      301 tgaaaccggc ttattgtctt caattaaaaa gttcattaaa ggaagcacgc ccaaggaaga
      361 gagagaaaat ccttcaaaac ggagtagaat tgaacgagat atagataata atttaatcac
      421 atcaacacca agaactggag aaaagcctga caaacagttg tctcgagtaa gacggaaaag
      481 tccagtcaat ggagaagctg gtagttatga aatgacaaat caacatataa aacaaaatgg
      541 aaaattagaa gataatcctt gttcaggtag tcctccaagg actacattgt tggggaccat
      601 attttcgcca gtcttcaact ttttttcacc agcaaataaa aatggaacgt caggttcaga
      661 ttccccagga caggctgtgg aagctgagga gatagtgaaa caacttgaca tggaacaggt
      721 ggatgaaatc actaccagta ctacgtcagc taatggagcg gcctactcaa atcaagcagt
      781 tcaagtgagg ccatcactca ataatggttt ggaagaagca gaagaaacag ttactcggga
      841 tatcccaccc cttacagcac cagtagctcc cgagagtggt tactcatcag ctcatgcaga
      901 ggccacctat gaggaagact gggaagtatt tgacccctat tatttcatca aacatgttcc
      961 gcctctgaca gaagaacaac taaataggaa acctgctctt cctctgaaaa cgagaagcac
     1021 accggagttc tccctggtct tagatctgga tgaaacgcta gtgcactgca gtctgaatga
     1081 gctggaagat gcagcactaa cttttccagt ccttttccaa gatgtcattt atcaggttta
     1141 tgtgagatta agaccattct tcagggaatt cctggagcga atgtctcaga tgtatgagat
     1201 cattcttttt actgcttcta agaaggtgta tgcagacaag ttactgaaca tactagaccc
     1261 taaaaagcaa ctggtcaggc accggctttt ccgtgaacat tgtgtttgtg tacaaggaaa
     1321 ttatataaag gacttaaata tccttggaag agacctttct aaaactataa taattgacaa
     1381 ctcaccacaa gcctttgcct atcagctttc taatggaatc cctatagaaa gctggtttat
     1441 ggataaaaat gacaatgaac tcctaaaatt gattccattt ctggagaagc ttgtagaact
     1501 gaatgaagat gtccggcctc acatcagaga cagatttcga ttgcatgatt tgctgccccc
     1561 agattaagtt cagagacttg tcagatcact gaagggggga gagaatgcag gacccttttg
     1621 gactaagaca aaaacattgc cattactgtt gaaattttgc atttttgtac cccgtcttgc
     1681 ttttcttatc tttggtgccc aatattaatc aagggttaga gaaagagact atcttggatt
     1741 gaacacatac agtgggcagg ctaaaacaga agcgtctgta gagtagaaca actccagtga
     1801 aacttatgac aggacatctg cagcttataa agaattctgt ttctgccacc agcagtttga
     1861 cctgtagcta cacaggattt tatgataatc acagaggtga gagtggactt tcattttctc
     1921 tctgtttggt gctctcagtg ggtttgtagc cacttttctg ttactttact attctcattt
     1981 caacaggaat ggccagtaaa agttgtttta tttttcctgt taaggtttat aaccttttta
     2041 catttctgac ctatattaga ttagaatctc atgatgcatt ccttttagtt aaggcgcttc
     2101 atagttttct ggaaatagtc aatttttagg tttttttttt ttaatttaca tttgaatggc
     2161 cgttttcctg ctttgtctgc ctgcatattg tatatttgtt taaaatattc tctactttta
     2221 gtccatgtaa gtttcatttt ttaaaaaatg catttatatt ttgttctgta atattctact
     2281 gtaggtgaaa tcttcaaaaa tcaagagact gggtagttaa gaatatatga atgactaata
     2341 ttcaaatgat ttgaaccatt gtgatgacat gtattccaga tggtaatatc ttgcaatggc
     2401 acacatttaa tggataaagg tatacctcag acttcactgt gctcactaac ctttgaggag
     2461 aacgagttca gtcacctgtt gggcttgatt cagttactgc tgcctctgga ttttctccag
     2521 gaatgaagta ttcagcacag tgactcagta tttttactct gcatgggctg gtagtacctc
     2581 tgttatgctc cggttacaat cggcttaaaa ctccgtgtaa cagtcttggt acctaacagt
     2641 agctatgcat aatcctgtgg cacagtacac tcccgggccc cagtgcagtt aatgtgctca
     2701 gagtggtttt ctatgctata tgaaaatagt cgtcacgcct tggttctcta atgcagctac
     2761 cacaagaggt tgatattttt atagtggcgt gtaatctcct tttcaggagg ctttttatgg
     2821 aaggtagaat ttgtaaaagt tagtatgctt tgcctctcaa ctgcattaac atgccgcagg
     2881 ctcagactgt ttttgtgtaa aggatgtcaa agaacggcac tttttctaaa gagaagtttg
     2941 atattttgta tgcttgttaa gaaagtacag tattggaaat taaaggtgga caactgataa
     3001 ttgaggagta tgtcagttaa ttttttatgt atattacctg tttacttgta caacttattg
     3061 tacaaattac atgcagcttc attttcaaat gaatccttaa aataaggaaa tctttttagg
     3121 aaaacattta atttttgtat ttttgatttt aaaggcatga gttgtcagtt ttcagtgtat
     3181 taatgaagat tttaactttt catcaggttg agtgttttct tactatatta tctgttgtgt
     3241 atgtagttag catattgtgt cactgaactg tttaaaaatc tagcatgtag agcaagcctg
     3301 ttttgtggaa aatccttatt cattaaaaaa ataatcatgg cagattttct gcaaaaaaaa
     3361 aaaaagcaaa agcatttgca attcagattt ttttatttta aagaaaaggt attttgcttg
     3421 caggaacaat actacagatt cattttaatg agaacctttg aaatgtattt atctttaggg
     3481 cacctgggca tctttatgct gtttgtctta tgtctttctt gaaataaaat gtacatatgt
     3541 tacctttaca tatgctcttt ctcaaaattg tggacctagt taacatcttg ccccatcatt
     3601 ttatgcttat acagcaaacc ccaaaatctg tacaagattg aatttttgac atacataatt
     3661 gttgaaagct taatcaggaa ttaaataaat atagtctcaa agcccttccc acaacttaaa
     3721 atgggaaaca taaacactta caccatagtg cctgtgggca ctttaataat aaaagagcag
     3781 gcccatgctc ggagagctcc tgtaagtcag ccaataggtg agtcaacaac acactgtgta
     3841 gagaaatata ttgtgggaaa gtttacatgg cctgagagtt gagaccaaat caatacattt
     3901 tttttccatt actttgagta attctaaagt ttgatattat aaagaagtta gccggcttct
     3961 tttcatttta atatgttatc tttcaatcat atcttttttt attggtagct gtagaacact
     4021 tccttttagt taattggagg tgtgtacttt ttaattgaga tgtgcccagc ctgtcagtgc
     4081 acacagcaca catgactgta gtaaatgcag gggccatggg tccgtgaggc acacagcaag
     4141 ctacctgtgt atacattaca actcttaagg acctattaaa attgtgctat ttccagttat
     4201 gaatgtttga cttttaagac attcttttaa atatttgtat cattgttaga ggatatttaa
     4261 ttggttgtat tttttaatcc catgtaatat atgtagtcct gaccagattt actaccattt
     4321 ttctctgggt cctaaaagag aattgatgac aattcgtaat caaaaattgt tttatatttg
     4381 ctagtatgta tatttattta tccaatggct ttatttgttt cccaaaattg ttttgggact
     4441 tgttgaaagc attgtgtaac ttctataaat ggctattttc ttgtaactgt cagtgatatg
     4501 gatgtgtaca ttgtttttat atatatatac atatatatat atacatacat acatatatat
     4561 atttctgggg taattttttt ttttagggct gactcttgtt tttaaagtta ccttttgcca
     4621 attactttct gttagctttt cctttcattc agccttctaa cggagctcat ttttattgtg
     4681 ttgtcaactt gcctgtgaga gacttcatct catcagtgaa gaaggcattt cattattcct
     4741 acaagtcata cagcaagcac agactcttca aggatcacat ctcttccacg tgtgtcagtc
     4801 acttaaagga cactgaagcc ttcactcctg tactgacaca atgtgtcata cactacatca
     4861 ctagctagtt aaggttttct gacctgactt ctcttcgtct tcctaggtat ttatttgtta
     4921 cctctttaaa tcttgtatgt ctaaattaac ttagaatagt tacccaccga ataactatgc
     4981 caagaactag gaaagaatgt ttattttatt tccccttata ggggaagagt ggactgggaa
     5041 caaaaatgta aggccaaaag gccttaggtt atcatcattc actttcttat tcctcttgtg
     5101 agctgtattt gactaaaggt ttggggtttt ttgtttgttt tccagtgata atgtatttga
     5161 ttatgccatt gcttttcatg tcttcccttg agttgaaaac ctgctaggag attgcataga
     5221 ataccttaaa gttctcagag taagaaccac aaaatcagta ccttatattc aaatgctact
     5281 taaattattg aaatccaagt cacattatta ggatacattt tcatattcat atttctgtta
     5341 tcttgaattg aaattccatt gtaaatcaat ttagtctttt aaaaaaggat ttaagagagc
     5401 aagtttattc tagcatatgg ttttaatatt agtattttaa gatatatagt gactaccaaa
     5461 cctacctgct aatcagaatt tcactgtgga gcttttaaac tatacagcat cctgaagcct
     5521 gggaagccac tttgtatcta gagcaggctt tgaaaattct gtatttttaa agctctccca
     5581 gtgatttaaa tagacaactt tggtatggta tatcctcttt taaacaatgt ggtttgagaa
     5641 taggttacaa agtttgacta gccatatcta tctctctctc tctctctctc tctctctctc
     5701 tctctctctc tctctctctc tctctctctc cctccctccc tccctccctc cccctccctc
     5761 cctcccttcc cctctctccc tggtaggttt tttaagtgct gggaccatat ttcacagacc
     5821 gtattcaaaa tggtggagga ataatgaaga ttgaggctac tgctccttgc cattcttgtc
     5881 attcatactt ttaaattaag agtgtgcatt tataaaactc tgaatagctg atcatttaca
     5941 tagcagaagg acatgtccct gaatgagacc attatatata ttaactgaaa tatttcacta
     6001 tttttttatt ttataaatct ttgtagaaat aagcaatgaa atgctacttt catcttttga
     6061 aatgggattt ttcaaggtag tgtccttttg gcattgaggt aggggggagt taatattctc
     6121 tctacttatt tccacatgaa tcaatatgaa gtcgtggaca tttaaaaatc tcaatttaat
     6181 ttctacttat ttactatgca gtatagccgt gaacaagtaa tgtagattta gttctctcat
     6241 cttcaaatgc cctgatcacc ctacctcaca gggttgttgt ggggataaat aaaactttta
     6301 tggaagta
//
