LOCUS       NM_031023               1616 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus chitobiase (Ctbs), mRNA.
ACCESSION   NM_031023
VERSION     NM_031023.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1616)
  AUTHORS   Hussain,M. and Wilson,J.B.
  TITLE     New paralogues and revised time line in the expansion of the
            vertebrate GH18 family
  JOURNAL   J Mol Evol 76 (4), 240-260 (2013)
   PUBMED   23558346
REFERENCE   2  (bases 1 to 1616)
  AUTHORS   Palmer,D.J., Kelly,V.C., Smit,A.M., Kuy,S., Knight,C.G. and
            Cooper,G.J.
  TITLE     Human colostrum: identification of minor proteins in the aqueous
            phase by proteomics
  JOURNAL   Proteomics 6 (7), 2208-2216 (2006)
   PUBMED   16502470
REFERENCE   3  (bases 1 to 1616)
  AUTHORS   Fisher,K.J. and Aronson,N.N. Jr.
  TITLE     Cloning and expression of the cDNA sequence encoding the lysosomal
            glycosidase di-N-acetylchitobiase
  JOURNAL   J Biol Chem 267 (27), 19607-19616 (1992)
   PUBMED   1527079
REFERENCE   4  (bases 1 to 1616)
  AUTHORS   Aronson,N.N. Jr., Backes,M. and Kuranda,M.J.
  TITLE     Rat liver chitobiase: purification, properties, and role in the
            lysosomal degradation of Asn-linked glycoproteins
  JOURNAL   Arch Biochem Biophys 272 (2), 290-300 (1989)
   PUBMED   2751306
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from M95768.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M95768.1, BC088129.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132291, SAMD00132292
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1616
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q44"
     gene            1..1616
                     /gene="Ctbs"
                     /note="chitobiase"
                     /db_xref="GeneID:81652"
                     /db_xref="RGD:621338"
     CDS             1..1104
                     /gene="Ctbs"
                     /note="di-N-acetylchitobiase; chitobiase, di-N-acetyl-"
                     /codon_start=1
                     /product="di-N-acetylchitobiase precursor"
                     /protein_id="NP_112285.1"
                     /db_xref="GeneID:81652"
                     /db_xref="RGD:621338"
                     /translation="MALSDLLELTLLLLLPLLERLSAEDCPCSEASLCRPIRHHRDFE
                     VFVFDVGQKTWKSYDWSQITTVAVFGKYDSELMCYAHSKGARVVLKGDVALKDIINPT
                     FRASWIAQKVALAKAQHMDGINIDIEQEVDCSSPEYEALTALVRETTEGFHREIEGSQ
                     VTFDVAWSPKGIDKRCYNYTGIADACDFLFVMSYDEQSQIWSECIAAANAPYNQTLTG
                     YGDYLRMGISPRKLVMGIPWYGYDYICLNLSKDDVCAIAKVPFRGAPCSDAAGHQVPY
                     RVIMKQVNSSVSGSQWNQDQQAPYYNYKDPTGRLHQVWYDNPRSISLKAAFVKHYGLR
                     GIGMWNANCLDYSDDALAREQTEEMWGALRPRL"
     exon            1..132
                     /gene="Ctbs"
                     /inference="alignment:Splign:2.1.0"
     exon            133..271
                     /gene="Ctbs"
                     /inference="alignment:Splign:2.1.0"
     exon            272..480
                     /gene="Ctbs"
                     /inference="alignment:Splign:2.1.0"
     exon            481..652
                     /gene="Ctbs"
                     /inference="alignment:Splign:2.1.0"
     exon            653..750
                     /gene="Ctbs"
                     /inference="alignment:Splign:2.1.0"
     exon            751..912
                     /gene="Ctbs"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1616
                     /gene="Ctbs"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcgctga gtgacctcct ggaactcact ctgctgctgc tgctgcccct gctggagcgg
       61 ctctcggccg aggactgccc gtgctccgag gcttctctct gccgaccgat ccgccaccac
      121 cgcgacttcg aggtctttgt gtttgatgtt ggacagaaaa cctggaaatc ttatgactgg
      181 tcgcagatta cgactgtggc agtttttgga aaatatgact cagaacttat gtgctatgct
      241 cattcgaaag gagccagggt agtgctaaaa ggtgatgtgg ccctgaagga catcattaat
      301 cctaccttca gagcgtcatg gatagcgcaa aaagttgcct tagccaaagc acaacacatg
      361 gatggaatta atatagacat agaacaggaa gttgattgct cgtcacctga atatgaagca
      421 ttgacagctt tggtcagaga aaccacagag ggtttccatc gtgagattga gggatcacag
      481 gtaacttttg atgtagcttg gtcaccaaag ggcatagaca aaaggtgcta taattatact
      541 gggattgcgg atgcctgcga ctttcttttt gtgatgtctt acgatgagca aagtcagatc
      601 tggtcagaat gtattgcagc cgccaatgct ccctacaatc agacattaac tggatatggt
      661 gactacctca ggatgggcat cagccccagg aaacttgtaa tgggtattcc ctggtatggc
      721 tatgattaca tttgcctaaa cctctcaaag gatgatgtct gcgccattgc aaaggtccct
      781 ttcagagggg ctccttgcag tgatgctgca gggcatcagg tgccctacag ggtcatcatg
      841 aagcaagtaa acagttctgt ttctggaagc cagtggaacc aagaccagca agctccgtac
      901 tataattaca aggatcccac tggccgtttg catcaggtgt ggtacgataa cccccggagc
      961 atctcactaa aggcagcatt cgtcaaacac tacggcttgc ggggcattgg catgtggaac
     1021 gcgaactgtc tggactactc agatgacgct ctagccagag agcaaacgga ggaaatgtgg
     1081 ggagccctga gaccacggct gtgatacata cagaggaatg tcttttgtca gacggttaga
     1141 tttgcaggac tggcctgtgt aagcagatct acctcttcaa gagataaaaa tatatatttt
     1201 gtcatgttac cctaacttac ttattggtct actcaataca caggaaagaa ataaagaaac
     1261 tattcatttg tacttggaaa atacatacat atcttaaata tccaggaatg taaaagcaaa
     1321 aacaagtcaa cttactctat taaatattcc tctgtttcag tattataatt atattatatt
     1381 ataattagaa aagttgcttt tagaattcca tgctgaattt ttcctcctgt tattaaaata
     1441 tactgttaaa aaccaatagg gatttttaaa aatgtataac tagtagacaa gtgaagatac
     1501 tggagaaggg agtgcacatg accatagtgt gttacacaca tgtatagact atcatagtaa
     1561 agcccattat ttttataatt aatatatgct aataaaagat gtgtaacttg aaatgg
//
