LOCUS       NM_001415876            3301 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus cleavage stimulation factor subunit 1 (Cstf1),
            transcript variant 1, mRNA.
ACCESSION   NM_001415876 XM_006235684
VERSION     NM_001415876.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3301)
  AUTHORS   Gruber,A.R., Martin,G., Keller,W. and Zavolan,M.
  TITLE     Means to an end: mechanisms of alternative polyadenylation of
            messenger RNA precursors
  JOURNAL   Wiley Interdiscip Rev RNA 5 (2), 183-196 (2014)
   PUBMED   24243805
  REMARK    Review article
REFERENCE   2  (bases 1 to 3301)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 3301)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 3301)
  AUTHORS   Chan,S., Choi,E.A. and Shi,Y.
  TITLE     Pre-mRNA 3'-end processing complex assembly and function
  JOURNAL   Wiley Interdiscip Rev RNA 2 (3), 321-335 (2011)
   PUBMED   21957020
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Jan 4, 2023 this sequence version replaced XM_006235684.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.251375.1,
                                           SRR26643292.15879.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-187               JAXUCZ010000003.1  181562955-181563141
            188-385             JAXUCZ010000003.1  181565061-181565258
            386-663             JAXUCZ010000003.1  181567930-181568207
            664-861             JAXUCZ010000003.1  181568342-181568539
            862-1252            JAXUCZ010000003.1  181569983-181570373
            1253-3301           JAXUCZ010000003.1  181572679-181574727
FEATURES             Location/Qualifiers
     source          1..3301
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..3301
                     /gene="Cstf1"
                     /note="cleavage stimulation factor subunit 1"
                     /db_xref="GeneID:311670"
                     /db_xref="RGD:1309267"
     exon            1..187
                     /gene="Cstf1"
                     /inference="alignment:Splign:2.1.0"
     exon            188..385
                     /gene="Cstf1"
                     /inference="alignment:Splign:2.1.0"
     CDS             217..1512
                     /gene="Cstf1"
                     /note="cleavage stimulation factor 50 kDa subunit;
                     cstF-50; CF-1 50 kDa subunit; CSTF 50 kDa subunit;
                     cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa"
                     /codon_start=1
                     /product="cleavage stimulation factor subunit 1"
                     /protein_id="NP_001402805.1"
                     /db_xref="GeneID:311670"
                     /db_xref="RGD:1309267"
                     /translation="MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVC
                     APSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETC
                     YVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNM
                     ENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAE
                     MLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNPSANM
                     YVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWE
                     ISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYILLPDERTISLCCWDSRTAERRNLL
                     SLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD"
     exon            386..663
                     /gene="Cstf1"
                     /inference="alignment:Splign:2.1.0"
     exon            664..861
                     /gene="Cstf1"
                     /inference="alignment:Splign:2.1.0"
     exon            862..1252
                     /gene="Cstf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..3301
                     /gene="Cstf1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcaggcgcac tgagctgtcg gagcccggaa gtggtgcacc aacggcctgt ccgatctacg
       61 gccgttctat cgcccgccgt gctctccaag gatcgggcgt ttgccggtca ctcacagtcc
      121 tttggattca aggctgtcgc ggaggtgatc agctcggaga aggtgaatga gcgtctcgaa
      181 cgtgccatca ggggaactgt catcctcttg tgcagaatgt acagaaccaa agtgggcctg
      241 aaggaccgcc agcagctcta caagctgatc atcagccagc tgctctatga cggatacatt
      301 agcatcgcca atggcctcat caacgagatc aagccacagt cggtgtgtgc gccctcggag
      361 cagctcctgc acctcatcaa gctagggatg gagaacgatg acactgcagt tcagtatgcc
      421 attggtcgct ctgacacggt tgcccctggc acagggattg acctggagtt tgatgcagac
      481 gtccaaacaa tgtcacccga ggcttcggag tatgaaacct gttatgtcac ctcccacaaa
      541 ggcccatgcc gagtggccac ctacagcaga gatgggcagt tgatagccac agggtctgcg
      601 gatgcttcca tcaagatact ggacacagag aggatgctgg ccaagagcgc catgcccatc
      661 gaggtcatga tgaatgagac tgcacaacag aacatggaga accacccagt gatccgaact
      721 ctttacgacc atgtggatga agtcacgtgt ctcgcttttc acccaacaga acagatcctg
      781 gcctccggct caagggatta tactctaaaa ttgtttgatt attccaaacc ctctgcaaaa
      841 agagccttta aatacattca ggaagctgag atgctgcgct ccatctcgtt ccacccttct
      901 ggagacttca tcctggtcgg gacccagcat cccacgcttc gcctctatga catcaacacc
      961 ttccagtgtt tcgtctcctg caatccccaa gaccagcaca ccgacgccat ctgctctgtc
     1021 aactataacc ctagtgccaa catgtacgtc actggcagca aggacggctg catcaagctg
     1081 tgggacggcg tctccaatcg ctgcatcaca acctttgaga aagctcacga cggggcagaa
     1141 gtctgttctg ccattttctc caagaattcc aagtacatcc tctcaagtgg aaaagactct
     1201 gtagctaaac tctgggaaat atccacggga cggacactgg tgaggtacac aggcgcaggg
     1261 ctgagtggac ggcaagtgca ccggacacag gctgtgttca accacactga ggactatatt
     1321 ttgctgccgg acgaaaggac catcagcctg tgctgctggg actctaggac agctgagcgc
     1381 aggaacctgc tgtccctggg ccacaacaac attgtgcgct gcatagtgca ctccccgacc
     1441 aaccctggct tcatgacgtg cagcgacgac ttccgagctc ggttctggta ccggaggtcc
     1501 accactgact gaactggccc cgctctgggg ttcttgtctc aggactctgc cctcctccct
     1561 gtcctgccac cggctgcgga agtgagcaac ttgcaccatc tgtggcgggt gtgtggccgc
     1621 ccagctcctg ccttggattt gtggtggaag ctctttttta ccttggtgta gaatcgtggt
     1681 gggaaaagtc ggaaacagat ctgtgcagct gtcctgtcac agtgattttg gtgtggtctt
     1741 caccagctta gcgagtgcag ggcttggcac ggccttcaac tctcgtgcct ggagaaggac
     1801 agaatatgga agtacttcct gggcctcggg tcacacttgt ctcctcctat gctgtccctc
     1861 cccttctgta ttttctttcc agatgcattt tggcacacaa ggagggccac atctctgagg
     1921 acctgggtcc catgtggaac caccttgcag ggatcccagt cccttcctga ggtgacatca
     1981 tcgtcctggt aataaagctc agatgcacaa cctcactgtt cctcctcctt cccgtcaaat
     2041 caaacgaagg ctcctggcct cccgtcttcc atcctgcagc gtcctctggg taccagctgt
     2101 acttgctggt aggatccaga actggcctgc aagccctgtg gagcaggagc cagcctgggc
     2161 tacattagcc cccttttcac accttaatcc cagctcttga gaggcagagg caggtggttc
     2221 tctgtgagat cctagcctgg tctaaatagt gagctccagg gcagccaggg ctacacagtg
     2281 aagccttgtc tcagaaagag gagggaatga tccgatctac tcagttcaag ccaccagagc
     2341 ccactgtccc cagccgaggg tgcaggaggg tgcaggggcc tcactcttgg aaggttgctg
     2401 cagcacccac gtctggtaca tttttctctc ttgaagtgtt tgggaagctg gcagtattct
     2461 ctctgtgtta agtcccatgt aggcggccca gccctgcatg acccacttac taacaaagtc
     2521 tgcttcctgt ttctcctgaa gaggaatcag gagctgggca gaagtacctg gaaatggtgt
     2581 gaggtcacca attaagcagt gaccaggccc cagtaagtca gtcccgagtt gtgagaactt
     2641 cggcataaaa ggtctgtccc agcctcacca ctgggtttat ggttgtaggc gtaaagagct
     2701 gtatttctgt ccgcaataag tgttaactga cacttttatt ttacattctg actttcaggt
     2761 atttgatcct ggctacccat aggttataag aaagctgatg gacagggaca gggacaaccc
     2821 gttctgtcta ggcaagcttt gctcttcttc ctctagagtc cctgttgctc tctggctatg
     2881 acactacaga gcagacttgt cacctctgtt cccacccaca ctcccagcac aagatgccag
     2941 ggtgctgcag tcacttgtga attaaaatga tgccacttcg tgcagcctct gctgggctgg
     3001 tctcaagggc cgggagtttc agggctgaca ggtgcaggac ggagatgctc ttctgtttcc
     3061 aaaacagttt cctcctctct cgctgccttc ctctctcctt ccttttaaaa gccgcattaa
     3121 cgtttgagct ggtgtacatg tcgagagtat cacacagact cattctcctc acagaacatc
     3181 ccgctaattg taccacataa caccctggca ttgaatgaag aatttatatc tggtcaggat
     3241 aaccttctat gttgtttttt aaagatgtga tttctaaaat aaatttttta tatcacagca
     3301 a
//
