LOCUS       NM_019258                707 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus cystatin 8 (Cst8), mRNA.
ACCESSION   NM_019258
VERSION     NM_019258.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 707)
  AUTHORS   Cornwall,G.A., Hsia,N. and Sutton,H.G.
  TITLE     Structure, alternative splicing and chromosomal localization of the
            cystatin-related epididymal spermatogenic gene
  JOURNAL   Biochem J 340 (Pt 1) (Pt 1), 85-93 (1999)
   PUBMED   10229662
REFERENCE   2  (bases 1 to 707)
  AUTHORS   Cornwall,G.A. and Hann,S.R.
  TITLE     Transient appearance of CRES protein during spermatogenesis and
            caput epididymal sperm maturation
  JOURNAL   Mol Reprod Dev 41 (1), 37-46 (1995)
   PUBMED   7619504
REFERENCE   3  (bases 1 to 707)
  AUTHORS   Cornwall,G.A., Orgebin-Crist,M.C. and Hann,S.R.
  TITLE     The CRES gene: a unique testis-regulated gene related to the
            cystatin family is highly restricted in its expression to the
            proximal region of the mouse epididymis
  JOURNAL   Mol Endocrinol 6 (10), 1653-1664 (1992)
   PUBMED   1280328
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF090692.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF090692.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..707
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..707
                     /gene="Cst8"
                     /note="cystatin 8"
                     /db_xref="GeneID:29679"
                     /db_xref="RGD:2434"
     exon            1..106
                     /gene="Cst8"
                     /inference="alignment:Splign:2.1.0"
     exon            107..425
                     /gene="Cst8"
                     /inference="alignment:Splign:2.1.0"
     CDS             195..623
                     /gene="Cst8"
                     /note="cystatin-related epididymal spermatogenic protein;
                     cystatin 8 (cystatin-related epididymal spermatogenic);
                     cystatin 8 (cystatin-related epididymal specific)"
                     /codon_start=1
                     /product="cystatin-8 precursor"
                     /protein_id="NP_062131.1"
                     /db_xref="GeneID:29679"
                     /db_xref="RGD:2434"
                     /translation="MTKPLLLSLIFFIIPAALAVDVDQSKNEVKAQRYFGSISISNAN
                     VKQCVWFAMKEYNKGSEDKYLFLLDKTLHATLQITDRMEYHIDVQISRSNCRKPLNNT
                     ENCIPQKNPKLEKKLSCSFLVGALPWNGEFDLLSKECKDV"
     exon            426..539
                     /gene="Cst8"
                     /inference="alignment:Splign:2.1.0"
     exon            540..707
                     /gene="Cst8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ataaatgtga actgagagtg ctggagaccc agaagaacca caagctgggg tggccagagt
       61 gaggaacgag cccagcagga agagcaagtt ggacagtcac agaaagtttg acagacctac
      121 agtggctgct tcattgcagc tcaagcccca aggagacgtg gaggacatca cttgtacctt
      181 ttgactgagg gaccatgaca aaacccttgt tgctctcctt gatcttcttc atcattccag
      241 cggccctggc agttgatgtg gatcagtcta agaatgaagt gaaggcacag aggtactttg
      301 gatccattag tatctccaat gccaatgtga agcaatgtgt ttggtttgcc atgaaagaat
      361 acaacaaagg aagtgaggac aaatacctct tccttctgga caagacactc catgccacac
      421 ttcagatcac agaccgcatg gaataccaca ttgatgttca gatctcccgc agcaattgca
      481 gaaaaccttt aaacaatact gaaaactgca tccctcaaaa aaatcccaaa ctggaaaaga
      541 aattaagttg cagctttctg gtaggagcac ttccctggaa tggtgagttc gacctgttga
      601 gcaaagaatg caaagatgtc taagggtgtc ttggtgtgcg cctccccctt ctgggtctgc
      661 ttttctctgt aataaagagc aacatctggt tcaagtctgt caccaac
//
