LOCUS       NM_153734                553 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cystatin 12 (Cst12), mRNA.
ACCESSION   NM_153734
VERSION     NM_153734.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 553)
  AUTHORS   Li,Y., Friel,P.J., Robinson,M.O., McLean,D.J. and Griswold,M.D.
  TITLE     Identification and characterization of testis- and
            epididymis-specific genes: cystatin SC and cystatin TE-1
  JOURNAL   Biol Reprod 67 (6), 1872-1880 (2002)
   PUBMED   12444065
  REMARK    GeneRIF: unusual amino acid sequence and highly restricted
            expression suggests that cystatins SC and TE-1 play a very
            specialized role in the testis and epididymis
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Dec 8, 2020 this sequence version replaced NM_153734.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF440736.1, BF406349.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-234               JAXUCZ010000003.1  156688192-156688425
            235-345             JAXUCZ010000003.1  156690981-156691091
            346-553             JAXUCZ010000003.1  156691845-156692052
FEATURES             Location/Qualifiers
     source          1..553
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..553
                     /gene="Cst12"
                     /note="cystatin 12"
                     /db_xref="GeneID:266776"
                     /db_xref="RGD:708514"
     exon            1..234
                     /gene="Cst12"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..426
                     /gene="Cst12"
                     /note="cystatin TE-1"
                     /codon_start=1
                     /product="cystatin-12"
                     /protein_id="NP_714956.2"
                     /db_xref="GeneID:266776"
                     /db_xref="RGD:708514"
                     /translation="MLWKSVLPVALIVLGIHDCNFKFIEIDKNDNDFVMSMEHVLFHF
                     NENQNDDFAYKFLRVRRSLRKKYTQKYLVDLEMGRTLCGKYDEDIDNCPLQEGPGEKK
                     VRCTYIVETRVWVTEFTILNSTCVQT"
     exon            235..345
                     /gene="Cst12"
                     /inference="alignment:Splign:2.1.0"
     exon            346..553
                     /gene="Cst12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcatcctc agctctcggt gcggattcta aggacagcta tgttgtggaa gtcggtcctg
       61 cccgtggcac tcattgtgct ggggattcat gattgcaact tcaagtttat agagatcgac
      121 aagaatgata atgattttgt catgtctatg gagcatgtcc tgttccactt caatgaaaac
      181 cagaatgatg attttgccta caagttcctg agagtccgga gaagtcttcg taagaaatat
      241 acgcagaagt atttagtaga cctggagatg ggccgtacac tttgtgggaa atatgatgaa
      301 gacattgaca attgtccatt gcaggaaggc ccaggagaga aaaaggtacg ctgcacttac
      361 attgtggaga ctagagtatg ggtcactgag ttcaccatct tgaacagcac ctgtgtgcag
      421 acttaagtgg ggcaagggtc tttctgtgcc tgtagctgaa ggctcctttc ctctagaggg
      481 tcactgtctg tgtccttggg tctttttagt accagcacaa ttaaagtctt acaaaccatt
      541 ttgagtcctt aaa
//
