LOCUS       NM_057144                930 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus cysteine and glycine rich protein 3 (Csrp3),
            mRNA.
ACCESSION   NM_057144 XM_006229237
VERSION     NM_057144.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Bloise,A.C., Dos Santos,J.A., de Brito,I.V., Bassaneze,V.,
            Gomes,L.F. and Alencar,A.M.
  TITLE     Discriminating aspects of global metabolism of neonatal
            cardiomyocytes from wild type and KO-CSRP3 rats using proton
            magnetic resonance spectroscopy of culture media samples
  JOURNAL   In Vitro Cell Dev Biol Anim 56 (8), 604-613 (2020)
   PUBMED   32914385
  REMARK    GeneRIF: Discriminating aspects of global metabolism of neonatal
            cardiomyocytes from wild type and KO-CSRP3 rats using proton
            magnetic resonance spectroscopy of culture media samples.
REFERENCE   2  (bases 1 to 930)
  AUTHORS   Levin,E., Leibinger,M., Gobrecht,P., Hilla,A., Andreadaki,A. and
            Fischer,D.
  TITLE     Muscle LIM Protein Is Expressed in the Injured Adult CNS and
            Promotes Axon Regeneration
  JOURNAL   Cell Rep 26 (4), 1021-1032 (2019)
   PUBMED   30673598
  REMARK    GeneRIF: Muscle LIM Protein Is Expressed in the Injured Adult CNS
            and Promotes Axon Regeneration.
REFERENCE   3  (bases 1 to 930)
  AUTHORS   Hernandez-Carretero,A., Weber,N., LaBarge,S.A., Peterka,V.,
            Doan,N.Y.T., Schenk,S. and Osborn,O.
  TITLE     Cysteine- and glycine-rich protein 3 regulates glucose homeostasis
            in skeletal muscle
  JOURNAL   Am J Physiol Endocrinol Metab 315 (2), E267-E278 (2018)
   PUBMED   29634311
REFERENCE   4  (bases 1 to 930)
  AUTHORS   Correll,R.N., Lynch,J.M., Schips,T.G., Prasad,V., York,A.J.,
            Sargent,M.A., Brochet,D.X.P., Ma,J. and Molkentin,J.D.
  TITLE     Mitsugumin 29 regulates t-tubule architecture in the failing heart
  JOURNAL   Sci Rep 7 (1), 5328 (2017)
   PUBMED   28706255
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 930)
  AUTHORS   Lange,S., Gehmlich,K., Lun,A.S., Blondelle,J., Hooper,C.,
            Dalton,N.D., Alvarez,E.A., Zhang,X., Bang,M.L., Abassi,Y.A., Dos
            Remedios,C.G., Peterson,K.L., Chen,J. and Ehler,E.
  TITLE     MLP and CARP are linked to chronic PKCalpha signalling in dilated
            cardiomyopathy
  JOURNAL   Nat Commun 7, 12120 (2016)
   PUBMED   27353086
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 930)
  AUTHORS   Flick,M.J. and Konieczny,S.F.
  TITLE     The muscle regulatory and structural protein MLP is a cytoskeletal
            binding partner of betaI-spectrin
  JOURNAL   J Cell Sci 113 (Pt 9), 1553-1564 (2000)
   PUBMED   10751147
REFERENCE   7  (bases 1 to 930)
  AUTHORS   Minamisawa,S., Hoshijima,M., Chu,G., Ward,C.A., Frank,K., Gu,Y.,
            Martone,M.E., Wang,Y., Ross,J. Jr., Kranias,E.G., Giles,W.R. and
            Chien,K.R.
  TITLE     Chronic phospholamban-sarcoplasmic reticulum calcium ATPase
            interaction is the critical calcium cycling defect in dilated
            cardiomyopathy
  JOURNAL   Cell 99 (3), 313-322 (1999)
   PUBMED   10555147
REFERENCE   8  (bases 1 to 930)
  AUTHORS   Rajavashisth,T., Qiao,J.H., Tripathi,S., Tripathi,J., Mishra,N.,
            Hua,M., Wang,X.P., Loussararian,A., Clinton,S., Libby,P. and
            Lusis,A.
  TITLE     Heterozygous osteopetrotic (op) mutation reduces atherosclerosis in
            LDL receptor- deficient mice
  JOURNAL   J Clin Invest 101 (12), 2702-2710 (1998)
   PUBMED   9637704
REFERENCE   9  (bases 1 to 930)
  AUTHORS   Kong,Y., Flick,M.J., Kudla,A.J. and Konieczny,S.F.
  TITLE     Muscle LIM protein promotes myogenesis by enhancing the activity of
            MyoD
  JOURNAL   Mol Cell Biol 17 (8), 4750-4760 (1997)
   PUBMED   9234731
REFERENCE   10 (bases 1 to 930)
  AUTHORS   Arber,S., Halder,G. and Caroni,P.
  TITLE     Muscle LIM protein, a novel essential regulator of myogenesis,
            promotes myogenic differentiation
  JOURNAL   Cell 79 (2), 221-231 (1994)
   PUBMED   7954791
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Dec 1, 2020 this sequence version replaced
            XM_006229237.2, NM_057144.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM055368.1, FM051120.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760475 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-94                JAXUCZ010000001.1  107682823-107682916 c
            95-233              JAXUCZ010000001.1  107674264-107674402 c
            234-402             JAXUCZ010000001.1  107669474-107669642 c
            403-535             JAXUCZ010000001.1  107667796-107667928 c
            536-629             JAXUCZ010000001.1  107666512-107666605 c
            630-930             JAXUCZ010000001.1  107664338-107664638 c
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..930
                     /gene="Csrp3"
                     /gene_synonym="CRP3; MLP"
                     /note="cysteine and glycine rich protein 3"
                     /db_xref="GeneID:117505"
                     /db_xref="RGD:71092"
     exon            1..94
                     /gene="Csrp3"
                     /gene_synonym="CRP3; MLP"
                     /inference="alignment:Splign:2.1.0"
     exon            95..233
                     /gene="Csrp3"
                     /gene_synonym="CRP3; MLP"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..706
                     /gene="Csrp3"
                     /gene_synonym="CRP3; MLP"
                     /note="cysteine-rich protein 3; LIM domain protein,
                     cardiac; muscle LIM protein; cysteine and glycine-rich
                     protein 3 (cardiac LIM protein); cysteine and glycine rich
                     protein 3 lacking the LIM1-domain; cysteine and glycine
                     rich protein 3 N-terminal nuclear localization sequence;
                     cysteine and glycine rich protein 3 c-terminal HA-tagged"
                     /codon_start=1
                     /product="cysteine and glycine-rich protein 3"
                     /protein_id="NP_476485.2"
                     /db_xref="GeneID:117505"
                     /db_xref="RGD:71092"
                     /translation="MPNWGGGAKCGACDKTVYHAEEIQCNGRSFHKTCFHCMACRKAL
                     DSTTVAAHESEIYCKVCYGRKYGPKGIGFGQGAGCLSTDTGEHLGLQFQQSPKPARAA
                     TTSNPSKFSAKFGESEKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVT
                     DKDGELYCKVCYAKNFGPTGIGFGGLTHQVEKKE"
     exon            234..402
                     /gene="Csrp3"
                     /gene_synonym="CRP3; MLP"
                     /inference="alignment:Splign:2.1.0"
     exon            403..535
                     /gene="Csrp3"
                     /gene_synonym="CRP3; MLP"
                     /inference="alignment:Splign:2.1.0"
     exon            536..629
                     /gene="Csrp3"
                     /gene_synonym="CRP3; MLP"
                     /inference="alignment:Splign:2.1.0"
     exon            630..930
                     /gene="Csrp3"
                     /gene_synonym="CRP3; MLP"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccctcaccga gccaaggctg gtgacagcct ttatatattt aaagaggata agagtcccct
       61 tactcagttg agctgacaga gaccacacag gcagattgac tttggcccct gagtcttcac
      121 catgccgaac tggggtggag gtgcaaaatg tggagcctgc gacaagacgg tttaccatgc
      181 agaagaaatc cagtgcaatg ggaggagctt ccataagacc tgtttccact gcatggcctg
      241 caggaaggct ctggacagca ccacagtggc agctcatgag tcagagatct actgtaaggt
      301 ctgctatggg cgcaagtatg gccccaaggg gatcgggttt ggacaaggcg ctggctgcct
      361 cagcacagac accggcgagc accttggcct gcagttccaa caatccccaa agccagcacg
      421 tgcagccacc acgagcaacc cttccaagtt ctctgcgaag tttggagaat cagagaagtg
      481 cccacgatgc ggaaagtcgg tatatgctgc tgagaaggtc atgggaggtg gcaagccctg
      541 gcataagacc tgctttcgct gcgccatctg tgggaagagc ctggagtcca caaatgtcac
      601 tgacaaggat ggggagcttt attgcaaagt ttgctatgcc aaaaattttg gccccacagg
      661 cattgggttt ggagggctta cacaccaagt ggaaaagaag gagtgaaacg gcgtgctttc
      721 tcacagccct gctagtcaac agcagggctg agtgacccca tagatgtaac ttggccccgc
      781 agcctccttt gtagctggac agcatttctc ttcagaagca gtcataggct gcactgacgt
      841 aacaagagac caccggaaat ggaatctgca aaagatgctt cattatttac tatttttggg
      901 gtgggagaga caataaacgt tttaatggta
//
