LOCUS       NM_001107409            1518 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus casein kinase 2 alpha 2 (Csnk2a2), mRNA.
ACCESSION   NM_001107409 XM_001061000 XM_226237
VERSION     NM_001107409.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1518)
  AUTHORS   Ottaviani D, Marin O, Arrigoni G, Franchin C, Vilardell J, Sandre
            M, Li W, Parfitt DA, Pinna LA, Cheetham ME and Ruzzene M.
  TITLE     Protein kinase CK2 modulates HSJ1 function through phosphorylation
            of the UIM2 domain
  JOURNAL   Hum Mol Genet 26 (3), 611-623 (2017)
   PUBMED   28031292
REFERENCE   2  (bases 1 to 1518)
  AUTHORS   Nishi A, Matamales M, Musante V, Valjent E, Kuroiwa M, Kitahara Y,
            Rebholz H, Greengard P, Girault JA and Nairn AC.
  TITLE     Glutamate Counteracts Dopamine/PKA Signaling via Dephosphorylation
            of DARPP-32 Ser-97 and Alteration of Its Cytonuclear Distribution
  JOURNAL   J Biol Chem 292 (4), 1462-1476 (2017)
   PUBMED   27998980
REFERENCE   3  (bases 1 to 1518)
  AUTHORS   Wei H, Liu L and Chen Q.
  TITLE     Selective removal of mitochondria via mitophagy: distinct pathways
            for different mitochondrial stresses
  JOURNAL   Biochim Biophys Acta 1853 (10 Pt B), 2784-2790 (2015)
   PUBMED   25840011
  REMARK    Review article
REFERENCE   4  (bases 1 to 1518)
  AUTHORS   Ivatt RM, Sanchez-Martinez A, Godena VK, Brown S, Ziviani E and
            Whitworth AJ.
  TITLE     Genome-wide RNAi screen identifies the Parkinson disease GWAS risk
            locus SREBF1 as a regulator of mitophagy
  JOURNAL   Proc Natl Acad Sci U S A 111 (23), 8494-8499 (2014)
   PUBMED   24912190
REFERENCE   5  (bases 1 to 1518)
  AUTHORS   de Mateo S, Castillo J, Estanyol JM, Ballesca JL and Oliva R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   6  (bases 1 to 1518)
  AUTHORS   Kulikova OG and Reikhardt BA.
  TITLE     Role of autophosphorylation in regulation of protein kinase CK2
            from rat neuronal chromatin
  JOURNAL   Biochemistry (Mosc) 63 (12), 1400-1406 (1998)
   PUBMED   9916157
REFERENCE   7  (bases 1 to 1518)
  AUTHORS   Orlandini M, Semplici F, Ferruzzi R, Meggio F, Pinna LA and
            Oliviero S.
  TITLE     Protein kinase CK2alpha' is induced by serum as a delayed early
            gene and cooperates with Ha-ras in fibroblast transformation
  JOURNAL   J Biol Chem 273 (33), 21291-21297 (1998)
   PUBMED   9694889
REFERENCE   8  (bases 1 to 1518)
  AUTHORS   Sarrouilhe D, Filhol O, Leroy D, Bonello G, Baudry M, Chambaz EM
            and Cochet C.
  TITLE     The tight association of protein kinase CK2 with plasma membranes
            is mediated by a specific domain of its regulatory beta-subunit
  JOURNAL   Biochim Biophys Acta 1403 (2), 199-210 (1998)
   PUBMED   9630630
REFERENCE   9  (bases 1 to 1518)
  AUTHORS   Pancetti F, Bosser R, Itarte E and Bachs O.
  TITLE     Changes in the activity of nuclear protein kinase CK2 during rat
            liver regeneration
  JOURNAL   Biochem Biophys Res Commun 218 (1), 35-39 (1996)
   PUBMED   8573159
REFERENCE   10 (bases 1 to 1518)
  AUTHORS   Diaz-Nido J, Mizuno K, Nawa H and Marshak DR.
  TITLE     Regulation of protein kinase CK2 isoform expression during rat
            brain development
  JOURNAL   Cell Mol Biol Res 40 (5-6), 581-585 (1994)
   PUBMED   7735332
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474006.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001061000.1, XM_226237.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168200.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1518
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p13"
     gene            1..1518
                     /gene="Csnk2a2"
                     /note="casein kinase 2 alpha 2"
                     /db_xref="GeneID:307641"
                     /db_xref="RGD:1306882"
     CDS             1..1053
                     /gene="Csnk2a2"
                     /EC_number="2.7.11.1"
                     /note="casein kinase II, alpha 2, polypeptide; casein
                     kinase 2, alpha prime polypeptide"
                     /codon_start=1
                     /product="casein kinase II subunit alpha'"
                     /protein_id="NP_001100879.1"
                     /db_xref="GeneID:307641"
                     /db_xref="RGD:1306882"
                     /translation="MPGPAAGSRARVYSEVNSLRSREYWDYEAHVPSWGNQDDYQLVR
                     KLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTV
                     KDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKP
                     HNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWS
                     LGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDDLYGYLKKYHIDLDPHFNDILGQ
                     HSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQ
                     PCAENTVLSSGLTAAR"
     exon            1..104
                     /gene="Csnk2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            105..216
                     /gene="Csnk2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            217..318
                     /gene="Csnk2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            319..369
                     /gene="Csnk2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            370..429
                     /gene="Csnk2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            430..513
                     /gene="Csnk2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            514..624
                     /gene="Csnk2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            625..726
                     /gene="Csnk2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            727..827
                     /gene="Csnk2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            828..976
                     /gene="Csnk2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1070
                     /gene="Csnk2a2"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1518
                     /gene="Csnk2a2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgcccggcc cggccgcggg cagtcgggcc cgggtctact ccgaggtgaa cagcctgagg
       61 agccgcgagt actgggacta cgaagcccac gtcccgagct ggggtaatca agatgattac
      121 caactggttc gaaaacttgg tcggggcaag tatagtgaag tatttgaggc cattaacatc
      181 accaacaatg agagggtggt tgtaaaaatt ctcaagccag tgaagaaaaa gaagataaaa
      241 cgagaggtta agattctgga gaaccttcgt ggtggaacaa atatcattaa gctgattgac
      301 actgtaaagg accctgtgtc aaagacacca gctttggtat ttgaatatat caataataca
      361 gattttaagc aactctacca gatcctgact gactttgata tccggtttta tatgtatgaa
      421 ctacttaaag ctctggatta ctgccacagc aagggaatca tgcacaggga tgtgaaacct
      481 cacaatgtca tgatagatca ccaacaaaaa aagctccggc tgattgactg gggtttggca
      541 gaattctacc atcctgctca ggagtacaat gtccgagtgg cctcgaggta cttcaaggga
      601 ccagagctcc ttgtggacta tcagatgtat gattacagct tggatatgtg gagcttgggc
      661 tgtatgttag caagcatgat attccgaaag gagccattct tccatgggca ggacaactat
      721 gaccagcttg ttcgaattgc caaggttctg gggacagatg acctgtatgg gtatctgaag
      781 aagtaccaca tagacctaga cccacacttc aatgatatcc tgggacagca ttcacggaag
      841 cgctgggaaa actttatcca tagtgagaac agacaccttg tcagccccga ggcccttgat
      901 cttcttgaca agctcctgcg gtacgaccat caacagagat tgaccgccaa agaggccatg
      961 gagcacccgt acttctaccc ggtggtgaag gagcagtccc agccttgtgc tgagaacacc
     1021 gtgctttcca gtggtctcac cgcagcacga tgaagcctgg ggaatcgacg gtctgttgcg
     1081 gttcctccca cttttccata agcagaacaa gaaccaaatc aaaacgtctt aacgcgtgta
     1141 gcgagatcac gtcccgagag cagacacaaa atggtggcag gcttggcgaa caggaactag
     1201 accacccgaa gggcagccca ccaccgtaaa tcagacctca cttccgaatg taaaaggttc
     1261 acatgccttt ggcttcctgt tgacttcctc ctgacccaga aagcatggga aatgtgaagg
     1321 gtatgcaaaa atggttgttg gttactgttg ctctccgtgc cctcgaccca tcccgtggct
     1381 gcctgttgct ccagcaaacc ccaaggacta gctgaccaca gaccacaaat gggatggggg
     1441 cagtgtatgg catggtgggc agttacatat tattttaaaa gtatatatat tattgaataa
     1501 aacgttttaa aagaagtg
//
