LOCUS       NM_001393750            4187 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus casein kinase 1, gamma 3 (Csnk1g3), transcript
            variant 2, mRNA.
ACCESSION   NM_001393750
VERSION     NM_001393750.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4187)
  AUTHORS   Chia,R., Haddock,S., Beilina,A., Rudenko,I.N., Mamais,A.,
            Kaganovich,A., Li,Y., Kumaran,R., Nalls,M.A. and Cookson,M.R.
  TITLE     Phosphorylation of LRRK2 by casein kinase 1alpha regulates
            trans-Golgi clustering via differential interaction with ARHGEF7
  JOURNAL   Nat Commun 5, 5827 (2014)
   PUBMED   25500533
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4187)
  AUTHORS   Zhai,L., Graves,P.R., Robinson,L.C., Italiano,M., Culbertson,M.R.,
            Rowles,J., Cobb,M.H., DePaoli-Roach,A.A. and Roach,P.J.
  TITLE     Casein kinase I gamma subfamily. Molecular cloning, expression, and
            characterization of three mammalian isoforms and complementation of
            defects in the Saccharomyces cerevisiae YCK genes
  JOURNAL   J Biol Chem 270 (21), 12717-12724 (1995)
   PUBMED   7759525
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.62823.1,
                                           SRR26643429.54204.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-448               JAXUCZ010000018.1  49497839-49498286
            449-871             JAXUCZ010000018.1  49523602-49524024
            872-912             JAXUCZ010000018.1  49532158-49532198
            913-982             JAXUCZ010000018.1  49536089-49536158
            983-1131            JAXUCZ010000018.1  49544413-49544561
            1132-1366           JAXUCZ010000018.1  49546202-49546436
            1367-1452           JAXUCZ010000018.1  49556819-49556904
            1453-1537           JAXUCZ010000018.1  49557028-49557112
            1538-1686           JAXUCZ010000018.1  49558822-49558970
            1687-1782           JAXUCZ010000018.1  49560069-49560164
            1783-1889           JAXUCZ010000018.1  49576210-49576316
            1890-1913           JAXUCZ010000018.1  49576834-49576857
            1914-4187           JAXUCZ010000018.1  49582555-49584828
FEATURES             Location/Qualifiers
     source          1..4187
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q11"
     gene            1..4187
                     /gene="Csnk1g3"
                     /note="casein kinase 1, gamma 3"
                     /db_xref="GeneID:64823"
                     /db_xref="RGD:621408"
     exon            1..448
                     /gene="Csnk1g3"
                     /inference="alignment:Splign:2.1.0"
     exon            449..871
                     /gene="Csnk1g3"
                     /inference="alignment:Splign:2.1.0"
     CDS             694..1968
                     /gene="Csnk1g3"
                     /EC_number="2.7.11.1"
                     /note="isoform 2 is encoded by transcript variant 2;
                     CKI-gamma 3; casein kinase I"
                     /codon_start=1
                     /product="casein kinase I isoform gamma-3 isoform 2"
                     /protein_id="NP_001380679.1"
                     /db_xref="GeneID:64823"
                     /db_xref="RGD:621408"
                     /translation="MDNKKKDKDKSDDRMARPSGRSGHSTRGTGSSSSGVLMVGPNFR
                     VGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQV
                     YYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIY
                     RDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSI
                     NTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL
                     CENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTP
                     VGAVQQDPALSSNREAHQHRDKIQQSKNQVVSSTNGELNTDDPTAGRSNAPITAPTEV
                     EVMDETNCQKVLNMWCCCFFKRRKRKTIQRHK"
     exon            872..912
                     /gene="Csnk1g3"
                     /inference="alignment:Splign:2.1.0"
     exon            913..982
                     /gene="Csnk1g3"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1131
                     /gene="Csnk1g3"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1366
                     /gene="Csnk1g3"
                     /inference="alignment:Splign:2.1.0"
     exon            1367..1452
                     /gene="Csnk1g3"
                     /inference="alignment:Splign:2.1.0"
     exon            1453..1537
                     /gene="Csnk1g3"
                     /inference="alignment:Splign:2.1.0"
     exon            1538..1686
                     /gene="Csnk1g3"
                     /inference="alignment:Splign:2.1.0"
     exon            1687..1782
                     /gene="Csnk1g3"
                     /inference="alignment:Splign:2.1.0"
     exon            1783..1889
                     /gene="Csnk1g3"
                     /inference="alignment:Splign:2.1.0"
     exon            1890..1913
                     /gene="Csnk1g3"
                     /inference="alignment:Splign:2.1.0"
     exon            1914..4187
                     /gene="Csnk1g3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttttcgctg atgcaggctg cttgggggcc tccgccgccg gagagactag acgctttcct
       61 ttttttttca ccccctcttt tctttcgttc tttttttttt tttccccctc ctctcatgta
      121 ttcacttccg ggtccggtgc cgctccggat gctcgaggcc gaaggatgtt tgacctccgg
      181 ataagcgagg cgccgccgtg cattcattcc cggttgcatc ggtggccaca gccgcggccc
      241 ggacggcgac tccgctctca gcggcggcag taaggaggag ccggcggcgg cgcgctgagc
      301 cagtagacgc gggcccgtcc ttccctcgct cgcgccttcc ttcctcggcc tcgttcatct
      361 tcagcggccg ccggcggcgg ggatgtgccg gcgctgacgg gcggacgcgc gccgggccga
      421 gcccgctgcc cgcggccgcg cctctgagct ctctatcggc accagcttat atcaccgaga
      481 agataattgt aaaggcatac cttgttgaga acataactga gaggttgtac ggatgggatg
      541 aacacgcgtc agttgcctgc ctgtctgctg gagtttggat gctagcgttg ctcataggga
      601 actgctgcct agggatgcac ctgctctaca gtaccccatt tcatcgtgct tgtctcgatt
      661 aaagaattca aagtggagta ccgcaaactt gatatggata ataaaaagaa agacaaggac
      721 aaatcagatg acagaatggc acggcccagt ggtcggtcag ggcacagcac tcgaggaact
      781 gggtcttctt catctggagt tttaatggtt ggacctaact ttagagttgg gaaaaaaatt
      841 ggatgtggca attttggaga attacgatta gggaaaaatt tatatacaaa tgaatatgtg
      901 gcgattaaac tggagcccat gaaatccaga gcaccacagc tgcatttgga atacagattc
      961 tataagcagt taggatctgg agatggtata cctcaagttt actattttgg cccttgtggt
     1021 aaatacaacg ctatggtgct ggaactgctg ggacctagtt tggaagattt gtttgacctc
     1081 tgtgatagaa cattttctct taaaaccgtt ctcatgatag ctatacagct gatttctcgc
     1141 atggagtatg tccactcaaa gaacttgata tacagagatg tgaagcctga gaatttctta
     1201 ataggacggc caggaaacaa agcccagcaa gtcattcaca tcatagattt tggtttggca
     1261 aaggaatata ttgatccaga gacaaagaaa catataccat acagagaaca caaaagcctt
     1321 actggaacag ccagatacat gagcataaac acacatctag gaaaagaaca gagcagaaga
     1381 gacgatttag aagctttagg acatatgttc atgtatttcc tgagaggcag tcttccttgg
     1441 caaggcctaa aggcagatac attaaaagag agatatcaga aaattggaga cacaaaacga
     1501 gccacaccga tagaagtgct gtgtgaaaac ttcccagaag aaatggcaac atatcttcgt
     1561 tacgtacgaa ggctagattt ttttgaaaag ccagactatg attacttaag aaagcttttt
     1621 actgacttgt ttgatcgcaa agggtatatg tttgattatg aatatgactg gattggtaaa
     1681 cagttgccta ctcctgtagg tgcagttcag caagacccgg ctctgtcatc gaacagagaa
     1741 gcacaccaac acagagacaa gatacagcag tctaaaaacc aggttgtaag ttctacaaat
     1801 ggagagctaa acacggatga ccccacggcg ggacggtcaa atgcacccat tacagcccct
     1861 acggaagtag aagtgatgga tgaaaccaac tgccagaaag tactgaacat gtggtgctgc
     1921 tgctttttca aacgaaggaa aaggaaaacc atacaacgtc acaagtgact ggacacagac
     1981 agagcctggg gagttactta catgtttata tgctgtctcg tgattaaaat catctctaga
     2041 gtgaccacat atattttcaa ggactcactc ttgaaacaaa aaagtcatac tttcatattt
     2101 cattttgtgg ttgtcttata ttcattcccc cacccctaat ttaactttat ggaagcttta
     2161 aaatcttgtc agaacatgag tgctttgccc atccttgaat ggaatggacc aatgaagtgt
     2221 attgatgaac acagttccat aggaaaacaa tacaggtgtc caaatgtcaa ttaattgtac
     2281 ctaatttgat ttctttatgt cttctataaa agcataatca aacaggaatt ttcctcccac
     2341 tggatactga agcagagaaa acagttgccc aaatattaaa aacaactttt ttgaacagtt
     2401 cctgttttgt gacatctgca ttgatttcag tatgaccgat ggtactgtta ttcatgaatc
     2461 atattggcct tctctttgtg aaatcatggt acagtcactg cccagaggta ctgaggaaaa
     2521 agtactatgg gattggcaaa ctgtggcggt caataagtcg gcagtgttgg aaatatgagc
     2581 tcggcttctg tggcgccact gtgtgaggtg cagctgcaga cgaagaagcg ccaggagcat
     2641 ttgcttaatg tcactctgct tccagatgat aatacatgat agatggcgag aactgagtac
     2701 tggagaagta atgtgtgtta gagtttaaaa acacactgag gaaaggatga caatgtgaac
     2761 ttcttttcag tgtgtaaggc tggagcccct taagagccta cttactgctc atggccacat
     2821 ttctctcaga agcagaaacc cgaggacgtg ccatacagtg gtggctgcct gttatgttgt
     2881 tcttcaatta aagaaaagaa tcatactccc agcaataaac actgggccac tctgctgccc
     2941 tctgtgcaca cgagtctctt gtattcagct tggctaggtc tctggaattc cctgtcttga
     3001 gcacaatgtc catgattgga gaatattctg gagagagggt gggcagggtg ctttgcctcc
     3061 atagctttca cagtgcctgc atatgaacag cgtaacagtt ctgttgttag ccaagtccat
     3121 tccacttcgc aagcctgctt tgtaaggacg taaggacaca ggcatacttc ttgtctcatg
     3181 ctgtcagccg ggttgtcggg agctacagac tggctagaaa gatgctgtga ccatgtcaca
     3241 cactcatctt tacttaggaa gttgtcgctc ctgccacgct ctctcctctg tcctacttgt
     3301 gagccttcag gtgtgcttat ttattttttt gtttgtctca aggtaacatt taaaatatgt
     3361 attaaaggaa aggaatccac atttttttac ttcattattg aatttacagg tatttaattg
     3421 tattttgtaa tttatttttc ttattagcca aaagttcaat gtgttgcttt gataaattgg
     3481 gcacccacat gaacacccca gatcaggacg ttgttcatct ttcttcttga tttcgaagac
     3541 ctacactcaa ctgagaaaac cttcgctgta taatctgatc aacagtttcc attcatttgt
     3601 acactgtcat gatatctgaa ctgcaggagt taaatactga gttttatttt gtttgctttg
     3661 agcaaggtag atggatattc tggccattta taatgtgaaa ccacttcttt acagtatttg
     3721 accaaatttg tgtgtctatg atatttgtaa atacatgcga tatctgtatt tcttatcata
     3781 aacctattta gttttattct cagtagggtt ttttggactg tacagtgttt atatgatctg
     3841 aactccttat acataagaag gtgtgtatat taatccaatt atggacttaa atattttaaa
     3901 gtatgaatac ccttatttgc tgcaaaggcc agtgtgtaga catttgcttt ttagcaatat
     3961 ttttaagtgc tccattttag tgccagagaa taagtctttg gcacagactg gtcagtaata
     4021 ggtaatgcag gtatgttcag gttaagccaa cgatgttttg catttttatg cttcttttct
     4081 gtcaacacta atgaaatcaa cattgcctga atgtctgaat actgaaacac agccctgttt
     4141 aaaagtatgt aactgaaaaa gaaataaata aaggtagttt ttttaaa
//
