LOCUS       NM_031562                789 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus casein kappa (Csn3), mRNA.
ACCESSION   NM_031562
VERSION     NM_031562.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Shekar,P.C., Goel,S., Rani,S.D., Sarathi,D.P., Alex,J.L., Singh,S.
            and Kumar,S.
  TITLE     kappa-casein-deficient mice fail to lactate
  JOURNAL   Proc Natl Acad Sci U S A 103 (21), 8000-8005 (2006)
   PUBMED   16698927
REFERENCE   2  (bases 1 to 789)
  AUTHORS   Palmer,D.J., Kelly,V.C., Smit,A.M., Kuy,S., Knight,C.G. and
            Cooper,G.J.
  TITLE     Human colostrum: identification of minor proteins in the aqueous
            phase by proteomics
  JOURNAL   Proteomics 6 (7), 2208-2216 (2006)
   PUBMED   16502470
REFERENCE   3  (bases 1 to 789)
  AUTHORS   Shan,L., Yu,M. and Snyderwine,E.G.
  TITLE     Global gene expression profiling of chemically induced rat mammary
            gland carcinomas and adenomas
  JOURNAL   Toxicol Pathol 33 (7), 768-775 (2005)
   PUBMED   16316942
REFERENCE   4  (bases 1 to 789)
  AUTHORS   Dev,B.C., Sood,S.M., DeWind,S. and Slattery,C.W.
  TITLE     Kappa-casein and beta-caseins in human milk micelles: structural
            studies
  JOURNAL   Arch Biochem Biophys 314 (2), 329-336 (1994)
   PUBMED   7979373
REFERENCE   5  (bases 1 to 789)
  AUTHORS   Nakhasi,H.L., Grantham,F.H. and Gullino,P.M.
  TITLE     Expression of kappa-casein in normal and neoplastic rat mammary
            gland is under the control of prolactin
  JOURNAL   J Biol Chem 259 (23), 14894-14898 (1984)
   PUBMED   6094580
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            On Nov 27, 2020 this sequence version replaced NM_031562.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: K02598.1, SRR26643295.48526.1
                                           [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                JAXUCZ010000014.1  20439793-20439830   c
            39-100              JAXUCZ010000014.1  20437834-20437895   c
            101-130             JAXUCZ010000014.1  20437181-20437210   c
            131-614             JAXUCZ010000014.1  20435488-20435971   c
            615-789             JAXUCZ010000014.1  20433277-20433451   c
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p21"
     gene            1..789
                     /gene="Csn3"
                     /gene_synonym="Csn10; Csnk"
                     /note="casein kappa"
                     /db_xref="GeneID:29188"
                     /db_xref="RGD:61990"
     exon            1..38
                     /gene="Csn3"
                     /gene_synonym="Csn10; Csnk"
                     /inference="alignment:Splign:2.1.0"
     exon            39..100
                     /gene="Csn3"
                     /gene_synonym="Csn10; Csnk"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..580
                     /gene="Csn3"
                     /gene_synonym="Csn10; Csnk"
                     /note="kappa-casein; Csn 10"
                     /codon_start=1
                     /product="kappa-casein precursor"
                     /protein_id="NP_113750.1"
                     /db_xref="GeneID:29188"
                     /db_xref="RGD:61990"
                     /translation="MMRNFIVVMNILALTLPFLAAEVQNPDSNCREKNEVVYDVQRVL
                     YTPVSSVLNRNHYEPIYYHYRTSVPVSPYAYFPVGLKLLLLRSPAQILKWQPMPNFPQ
                     PVGVPHPIPNPSFLAIPTNEKHDNTAIPASNTIAPIVSTPVSTTESVVNTVANTEAST
                     VPISTPETATVPVTSPAA"
     exon            101..130
                     /gene="Csn3"
                     /gene_synonym="Csn10; Csnk"
                     /inference="alignment:Splign:2.1.0"
     exon            131..614
                     /gene="Csn3"
                     /gene_synonym="Csn10; Csnk"
                     /inference="alignment:Splign:2.1.0"
     exon            615..789
                     /gene="Csn3"
                     /gene_synonym="Csn10; Csnk"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagcaaaccc tactgccaag aactgactcc gtgtgaaggt gcaatgatga ggaattttat
       61 cgtagttatg aatatcctgg cactaactct gccctttttg gctgcagagg tgcaaaaccc
      121 agactcaaac tgccgtgaga agaacgaagt agtgtacgat gtgcaaagag tcctgtacac
      181 acctgtcagc tctgtcctga accgcaatca ttatgaacct atttactacc actacaggac
      241 ctctgtgcct gttagcccat acgcgtattt cccagttggt ctaaaactac ttctacttcg
      301 gtctccagcc caaatcctca aatggcaacc aatgccaaat ttcccccagc ctgttggagt
      361 acctcatccc attccaaacc catcctttct tgccattccc acaaatgaaa agcatgataa
      421 caccgccatt ccagccagca ataccattgc tcccattgtg tccacaccag tttctaccac
      481 agagtcagtg gtaaatactg tggccaatac cgaagcttcc acagtgccta tcagtacccc
      541 ggagactgcc acagtcccag tgacctcacc tgcagcataa aagcgcaaag gaaacattga
      601 agaagacagt caaggtctga aaccaaattc caacttcaaa ctcttcttca gggatttgtc
      661 taccaccatt caagagaaaa tgcaattttc acagattcag atctttttct tcttcctata
      721 cattttacat tgaagccaca gttaattttg tttttttttg attcttgaag aataaagtta
      781 atgaaatgc
//
