LOCUS       XM_006243164            2295 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus C-terminal Src kinase (Csk),
            transcript variant X2, mRNA.
ACCESSION   XM_006243164
VERSION     XM_006243164.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051343.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006243164.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006243164.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2295
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2295
                     /gene="Csk"
                     /note="C-terminal Src kinase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 47 ESTs, 1 long SRA read, 13 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 110 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:315707"
                     /db_xref="RGD:1308800"
     CDS             263..1615
                     /gene="Csk"
                     /codon_start=1
                     /product="tyrosine-protein kinase CSK isoform X1"
                     /protein_id="XP_006243226.1"
                     /db_xref="GeneID:315707"
                     /db_xref="RGD:1308800"
                     /translation="MSAIQASWPSGTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKD
                     PNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETG
                     LFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTTDA
                     DGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNK
                     VAVKCIKNDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVD
                     YLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFG
                     LTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPL
                     KDVVPRVEKGYKMDAPDGCPPAVYDVMKNCWHLDAATRPTFLQLREQLEHIRTHELHL
                     "
ORIGIN      
        1 acactactgg gaaggagcca cgagggagat actatcctgc accacaagag actcggctta
       61 gatcagctga gtcctacctt cccacccccc aactcccgtg tggagagcag agtgggaagt
      121 ggctggaccc cggaggaaga gaagcagtat gggccggact cctgggagtt tgccctttcc
      181 tgttcagggc ttccctgaag ctctaatggt accaagtaac agaccggcct tcctgtagca
      241 cggggacgcc agatctcaga agatgtcggc tatacaggcc tcctggccat ccggtacaga
      301 atgtattgcc aagtacaact tccatggcac tgccgagcaa gaccttccct tctgcaaagg
      361 agatgtgctc accattgtgg ctgtcaccaa ggaccccaac tggtacaaag ccaaaaacaa
      421 agtgggccgt gagggcatca tcccagccaa ctatgtccag aagcgtgagg gtgtgaaggc
      481 aggcaccaag ctcagcctta tgccctggtt ccacggcaag atcacacggg agcaggcgga
      541 gcggcttctc tacccaccag agacaggcct gttcctggtg cgggaaagca ccaactaccc
      601 tggggactac acactgtgtg tgagctgtga aggcaaggtg gagcactacc gcatcatgta
      661 tcacgcgagc aagctgagca ttgatgagga ggtgtacttc gagaacctca tgcagctggt
      721 ggagcactac accacagatg ccgacggact ctgcactcgc ctcatcaaac caaaggtcat
      781 ggagggcaca gtggcggccc aagatgaatt ctaccgcagt ggctgggccc tgaacatgaa
      841 ggaactgaag ctgctacaga cgataggaaa gggggagttt ggagatgtga tgctggggga
      901 ttaccgaggc aacaaagttg cagtcaagtg cattaagaat gatgctacag cccaggcctt
      961 cctggctgaa gcctctgtca tgacgcagct tcggcacagc aacctagtcc agctactggg
     1021 tgtgattgtg gaggagaagg gtgggctcta catcgtcaca gagtacatgg ccaaggggag
     1081 tttggtggac tatcttcgat cacgtggtcg ttcggtgcta ggcggagact gtctcctcaa
     1141 attctcacta gacgtctgtg aagccatgga gtacctggag ggtaacaatt ttgtgcaccg
     1201 ggacttggct gcccggaatg tgctggtgtc tgaggacaac gtggccaaag tcagtgactt
     1261 tggcctcact aaggaagctt ccagcactca ggacacaggc aaactgccag tcaagtggac
     1321 agctcctgaa gccttgagag agaagaaatt ttccaccaag tctgatgtgt ggagtttcgg
     1381 aatccttctc tgggaaatct attccttcgg gcgagtgcct tacccaagaa ttcccctgaa
     1441 ggacgtcgtc cctcgggtgg aaaagggcta taagatggac gctccggatg gctgcccacc
     1501 cgcagtctat gatgttatga agaactgctg gcacctggat gctgccacgc ggcccacctt
     1561 tctgcagctt cgagagcagc tcgagcacat cagaacccat gagctgcacc tgtgacctct
     1621 gcctccacct aggccatggc cttgcaggga tggggcctag aagatacaga tttggtgccc
     1681 tgctgcttgc tgggcctgaa cttgaactga gccccagcgg gctggtaggc ttcttgcctc
     1741 tgacctgcct gtcccttctg gccccccaga gaccccacct aggcctggca tcttctctca
     1801 tggacccacc tatagggctt agggcgccca ctgaaggggc tgagaagaga ggaggccgag
     1861 gagcgggagg cagtgctcct gtggtcggcc ttctctcggc cccatcattc gccttcttag
     1921 agttttattc ctttcctttt ttgagatttt tttccgtgtg tttatttttt attatttttc
     1981 aacataagga gaaagaaagt acccagcaaa tgggcatttt acaagaagta cgaatcttat
     2041 ttttcctgtc ctgcccctgg gggtggggag gaatcagcct ctctctaggg acccatcacc
     2101 ccagcctgtc ccccatcctg tgttccatgt ccagtgttgc ctcggtcgcc tatgtttgcg
     2161 cttgaccatg tgcgctgttt gcatgtgccc aaggcaggca tctgtcaggg gcttggattt
     2221 catgtgctgt ggccgctcac ccacactgcc ttgtgagatg gaatcgtaat aaaccactcc
     2281 atgaggacac cgcca
//
