LOCUS       NM_001106616            3636 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus chondroitin sulfate
            N-acetylgalactosaminyltransferase 2 (Csgalnact2), mRNA.
ACCESSION   NM_001106616 XM_001056935 XM_232316
VERSION     NM_001106616.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3636)
  AUTHORS   Izumikawa T, Okuura Y, Koike T, Sakoda N and Kitagawa H.
  TITLE     Chondroitin 4-O-sulfotransferase-1 regulates the chain length of
            chondroitin sulfate in co-operation with chondroitin
            N-acetylgalactosaminyltransferase-2
  JOURNAL   Biochem J 434 (2), 321-331 (2011)
   PUBMED   21138417
REFERENCE   2  (bases 1 to 3636)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 3636)
  AUTHORS   Uyama T, Kitagawa H, Tamura Ji J and Sugahara K.
  TITLE     Molecular cloning and expression of human chondroitin
            N-acetylgalactosaminyltransferase: the key enzyme for chain
            initiation and elongation of chondroitin/dermatan sulfate on the
            protein linkage region tetrasaccharide shared by heparin/heparan
            sulfate
  JOURNAL   J Biol Chem 277 (11), 8841-8846 (2002)
   PUBMED   11788602
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473964.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_232316.4, XM_001056935.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ221326.1, SRR8487227.298507.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3636
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..3636
                     /gene="Csgalnact2"
                     /gene_synonym="Galnact2; RGD1563660"
                     /note="chondroitin sulfate
                     N-acetylgalactosaminyltransferase 2"
                     /db_xref="GeneID:297554"
                     /db_xref="RGD:1563660"
     exon            1..119
                     /gene="Csgalnact2"
                     /gene_synonym="Galnact2; RGD1563660"
                     /inference="alignment:Splign:2.1.0"
     exon            120..1040
                     /gene="Csgalnact2"
                     /gene_synonym="Galnact2; RGD1563660"
                     /inference="alignment:Splign:2.1.0"
     CDS             380..2008
                     /gene="Csgalnact2"
                     /gene_synonym="Galnact2; RGD1563660"
                     /EC_number="2.4.1.174"
                     /note="chondroitin sulfate GalNAcT-2"
                     /codon_start=1
                     /product="chondroitin sulfate
                     N-acetylgalactosaminyltransferase 2"
                     /protein_id="NP_001100086.1"
                     /db_xref="GeneID:297554"
                     /db_xref="RGD:1563660"
                     /translation="MSRRGPILHSRTQWLLVGLALLFSLVLFMYLLECAPQTDGNASL
                     PGVVRENYGKEYYQALLQEQEEHYQTRATSLKRQIAQLKQELQDMSEKMRALQERKKL
                     GANGIGYQGNREQTPSDLLEFLHSQIDRAEVSIGAKLPSEYGVVPFESFTLMKVFQLE
                     MGLTRHPEEKPVRKDKRDELVEVIEAGLEVINNPDEDDEQEDEEGPLGEKLIFNENDF
                     IEGYYRTERDKGTHYELFFKKADLMEYRHVTLFRPFGPLMKVKSELIDITRSVINIIV
                     PLAERTEAFSQFMQNFRDVCIHQDKRIHLTVVYFGKEGLSTVKSILESVSSESNFHNY
                     TLVSLNEEFNRGRGLNVGARTWDKGEVLMFFCDVDIYFSAEFLNSCRLNAEPGKKVFY
                     PVVFSLYNPAIVYANQEVPPPVEQQLVHKKDSGFWRDFGFGMTCQYQSDFLSVGGFDM
                     EVKGWGGEDVHLYRKYLHGDLIVIRTPVPGLFHLWHEKHCADELTPEQYRMCIQSKAM
                     NEASHSHLGMMVFREEIEMHLRKQAYRTNSEAAG"
     exon            1041..1257
                     /gene="Csgalnact2"
                     /gene_synonym="Galnact2; RGD1563660"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1359
                     /gene="Csgalnact2"
                     /gene_synonym="Galnact2; RGD1563660"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1538
                     /gene="Csgalnact2"
                     /gene_synonym="Galnact2; RGD1563660"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1633
                     /gene="Csgalnact2"
                     /gene_synonym="Galnact2; RGD1563660"
                     /inference="alignment:Splign:2.1.0"
     exon            1634..1715
                     /gene="Csgalnact2"
                     /gene_synonym="Galnact2; RGD1563660"
                     /inference="alignment:Splign:2.1.0"
     exon            1716..3636
                     /gene="Csgalnact2"
                     /gene_synonym="Galnact2; RGD1563660"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 catttcctcg cgcgcgccgg aagtggcggt gctccgcggc ggcgcgcggg gccagccagc
       61 gcagggcgct ggccaggtgt acagctcccc agaggcggca gcgctgagcg gcgagcgcga
      121 acagtcacca cccagataat ggattatata gaccagattg cgtagtgtgg atatcatggt
      181 aacaatacag gaagtataaa tttctcactt ctgcaagtag tcatgactac tgaagaagga
      241 atcttttaaa atgacagcag agctcatttg ggtacctctc atggaaatcc taattttgtt
      301 tttaactttt ggtaactttt cgctgaagtc atgaacaagc aaagagcttg ccttgttagg
      361 caaacacaca ctagtgagaa tgtctagaag aggaccgatt cttcacagcc ggacccagtg
      421 gctgctggtg ggccttgctt tgcttttcag tctagtatta tttatgtacc tcctggaatg
      481 tgccccccag actgatggaa atgcttctct ccctggtgtg gttagagaaa attatggtaa
      541 agaatattac caagccctcc tgcaggagca agaagaacat taccaaacca gggcaaccag
      601 tttgaaacgc cagattgccc agctaaagca agaactacaa gatatgagtg agaagatgag
      661 agccttgcaa gagaggaaga agctaggggc taacggcata ggctatcagg gcaacagaga
      721 gcagacaccc agcgacctct tagagtttct tcattcccag atcgacagag ctgaagtcag
      781 cataggggcc aaactaccca gtgagtatgg agtcgttccc tttgaaagtt ttactttaat
      841 gaaagtattt cagttggaaa tgggtctcac gcgccatcct gaagaaaagc cagttagaaa
      901 agacaaacga gatgaattgg tagaagttat tgaagctggc ttggaggtca ttaataatcc
      961 tgatgaagat gatgaacagg aagatgagga gggccccctt ggagagaaac tgatatttaa
     1021 tgaaaatgac ttcatagaag gctattaccg cactgagaga gataaaggca cgcactatga
     1081 gctgtttttt aagaaggcag accttatgga atacaggcat gtgaccctct tccgcccttt
     1141 cggacctctc atgaaagtga agagcgagct gattgacatt acaagatcgg ttattaatat
     1201 cattgtgccg cttgctgaga ggacagaagc cttttcacag tttatgcaga acttcagaga
     1261 tgtttgtatt catcaagaca agagaattca tctcaccgtt gtgtattttg ggaaagaagg
     1321 actatctaca gtcaagtcta ttctagaatc tgtctcaagt gagtctaatt ttcacaatta
     1381 caccttggtc tcattgaacg aagaatttaa tcgtggacga ggactaaatg tgggtgcccg
     1441 aacttgggac aagggagagg tcttgatgtt tttctgtgat gttgatatat atttctcagc
     1501 tgaattcctt aacagctgcc ggttaaatgc tgagccaggt aaaaaagtgt tttaccccgt
     1561 ggtgttcagt ctttacaacc ctgccatcgt ctatgccaac caggaagtgc cacctcccgt
     1621 ggagcagcag ctggttcata aaaaggactc tggtttttgg agagattttg gctttgggat
     1681 gacgtgtcaa tatcaatcag attttctgag tgtcggtgga ttcgacatgg aagtaaaagg
     1741 ctggggtgga gaagatgttc atctttaccg aaagtactta catggtgatc ttattgtgat
     1801 tcggactcca gttcctggcc ttttccacct ctggcatgag aaacactgtg cggacgagct
     1861 gacccctgag caataccgaa tgtgcatcca atccaaagcc atgaacgagg cctctcactc
     1921 ccacctggga atgatggtct tcagggagga aatagagatg cacctccgca aacaggcgta
     1981 cagaaccaac agcgaggccg ctgggtgaca ggcagcgcat gggagtctga gccacaagcc
     2041 agcactgttt attcagcctt aactccaact ctagattctg tgcctcttcc agagaaggct
     2101 ttgcccatgt tctttctgaa ataatctgta gctcaacttg atgtaagaag aaaatgcagg
     2161 cgtcttgatg gaaagcctgc gctgtgaagg tactgtggta tgcaccagtt gacaaagtga
     2221 aattgatatt tgtccccaaa tcgtttgaat tagactctgc ctggtacctg tattctgatt
     2281 ggtcgtggat gtgcgcaagg ctgatgttgg gttggctagc accctcctcc agggtacaga
     2341 gtattggctg gtcatggtgt tcaggtggct atcacctgct gaccactaag ccagtcactc
     2401 gacttgagtc tttaaatgaa gcttttattg atcatatgta gaaaattttt cacagagaat
     2461 aattaacata tctgaaacct gcagtccttc atgaaggcat aaatctaaac cccttagttt
     2521 tatgttgctt tacctctaaa tatattttta agcaaatgga tatagtacat ttaatttaga
     2581 atttatggtt tgattataaa taaaatatat tgttatgtta ccaatgttca gaatgcatag
     2641 tcaaactgtc atagattgtt ttgagcattt tattatattg gaatgcagga aagtagctgt
     2701 gtttggaaca tcattttata taagccagat gtatcagaac cttcctgaag agacacagaa
     2761 gatatgaaca ttatagcatg gttttgtatg cttttgtttg cactgtcttg tttagcatag
     2821 ctacatatat atttattttc tagtatgtta atttttgcca caaatttgct agcatttgta
     2881 ttatacttcc agttgaaaga gttttattga aaaaaaaacc aatttaatgt gttatataat
     2941 aagatcaccc ttgatttaag aaaagtaatc tgataaaaat atgaattatg gagtacttta
     3001 aaaaacatgt acagattaat gctattttaa ttgaaatgta aattatttta atgagacaag
     3061 atgaataaga aattatgttc cggtagaact gtactataat atttatcaca catggatatt
     3121 ttatcatccg gccatcactt gatcaggaac tggcactatg gcgagggcgg gcttgctttc
     3181 atagcccttg actcttacag ggctatttgt atatagccca tgcgaactcg gaaagtcact
     3241 gtttggttca gtaaatcagc cacctcagac gtgacaaatg ccaaatctct aggtgctaag
     3301 gtgagtccac tccaatggta gctaactgct gagggctccg ggagtgcgag gtgttttaag
     3361 atgtataaag tgctctctgc agaataagca gagccaatgt ctcctttgta cacacttatt
     3421 tattgtaaag agcagtgacc atggtattta aagttagggt acttagtgat ttataaaggt
     3481 ggtttcagct tggttttgag ataatcaaat gatttttact ttaactccta tttttttaaa
     3541 actagctttt atttgaagat gggagctaag atttgaaagc attactatat tttttacatt
     3601 aagtggtacc aataaagtat tttgttacca aaagcc
//
