LOCUS       NM_054006               4157 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus cold shock domain containing E1 (Csde1),
            transcript variant 1, mRNA.
ACCESSION   NM_054006 XM_039101589
VERSION     NM_054006.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Youn,J.Y., Dunham,W.H., Hong,S.J., Knight,J.D.R., Bashkurov,M.,
            Chen,G.I., Bagci,H., Rathod,B., MacLeod,G., Eng,S.W.M., Angers,S.,
            Morris,Q., Fabian,M., Cote,J.F. and Gingras,A.C.
  TITLE     High-Density Proximity Mapping Reveals the Subcellular Organization
            of mRNA-Associated Granules and Bodies
  JOURNAL   Mol Cell 69 (3), 517-532 (2018)
   PUBMED   29395067
REFERENCE   2  (bases 1 to 4157)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 4157)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 4157)
  AUTHORS   Dinur,M., Kilav,R., Sela-Brown,A., Jacquemin-Sablon,H. and
            Naveh-Many,T.
  TITLE     In vitro evidence that upstream of N-ras participates in the
            regulation of parathyroid hormone messenger ribonucleic acid
            stability
  JOURNAL   Mol Endocrinol 20 (7), 1652-1660 (2006)
   PUBMED   16469771
  REMARK    GeneRIF: Unr, together with the other proteins in the RNA binding
            complex, determines PTH mRNA stability.
REFERENCE   5  (bases 1 to 4157)
  AUTHORS   Chang,T.C., Yamashita,A., Chen,C.Y., Yamashita,Y., Zhu,W.,
            Durdan,S., Kahvejian,A., Sonenberg,N. and Shyu,A.B.
  TITLE     UNR, a new partner of poly(A)-binding protein, plays a key role in
            translationally coupled mRNA turnover mediated by the c-fos major
            coding-region determinant
  JOURNAL   Genes Dev 18 (16), 2010-2023 (2004)
   PUBMED   15314026
REFERENCE   6  (bases 1 to 4157)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   7  (bases 1 to 4157)
  AUTHORS   Jeffers,M., Paciucci,R. and Pellicer,A.
  TITLE     Characterization of unr; a gene closely linked to N-ras
  JOURNAL   Nucleic Acids Res 18 (16), 4891-4899 (1990)
   PUBMED   2204029
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On or before Dec 20, 2022 this sequence version replaced
            XM_039101589.1, NM_054006.2.
            
            ##Evidence-Data-START##
            CDS exon combination :: X52311.1, SRR26360176.1239378.1
                                    [ECO:0000331]
            RNAseq introns       :: partial sample support SAMEA5760383,
                                    SAMEA5760386 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               JAXUCZ010000002.1  193234546-193234661
            117-402             JAXUCZ010000002.1  193243173-193243458
            403-520             JAXUCZ010000002.1  193243486-193243603
            521-719             JAXUCZ010000002.1  193252415-193252613
            720-829             JAXUCZ010000002.1  193253644-193253753
            830-922             JAXUCZ010000002.1  193254152-193254244
            923-1020            JAXUCZ010000002.1  193254854-193254951
            1021-1102           JAXUCZ010000002.1  193257404-193257485
            1103-1231           JAXUCZ010000002.1  193257943-193258071
            1232-1357           JAXUCZ010000002.1  193258188-193258313
            1358-1570           JAXUCZ010000002.1  193258975-193259187
            1571-1711           JAXUCZ010000002.1  193261072-193261212
            1712-1876           JAXUCZ010000002.1  193261302-193261466
            1877-1984           JAXUCZ010000002.1  193263410-193263517
            1985-2160           JAXUCZ010000002.1  193264471-193264646
            2161-2273           JAXUCZ010000002.1  193265267-193265379
            2274-2393           JAXUCZ010000002.1  193265818-193265937
            2394-2572           JAXUCZ010000002.1  193267524-193267702
            2573-2736           JAXUCZ010000002.1  193268408-193268571
            2737-2869           JAXUCZ010000002.1  193269474-193269606
            2870-4157           JAXUCZ010000002.1  193270014-193271301
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..4157
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /note="cold shock domain containing E1"
                     /db_xref="GeneID:117180"
                     /db_xref="RGD:619726"
     exon            1..116
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            117..402
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            403..520
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     CDS             521..2917
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /note="isoform 1 is encoded by transcript variant 1; cold
                     shock domain-containing protein E1; upstream of NRAS; cold
                     shock domain containing E1, RNA binding-like"
                     /codon_start=1
                     /product="cold shock domain-containing protein E1 isoform
                     1"
                     /protein_id="NP_446458.1"
                     /db_xref="GeneID:117180"
                     /db_xref="RGD:619726"
                     /translation="MSFDPNLLHNNGHNGYPNGTSAALRETGVIEKLLTSYGFIQCSE
                     RQARLFFHCSQYNGNLQDLKVGDDVEFEVSSDRRTGKPIAIKLVKIKPEIHPEERMNG
                     QVVCAVPHNLESKSPAAPGQSPTGSVCYERNGEVFYLTYTSEDVEGNVQLETGDKINF
                     VIDNNKHTGAVSARNIMLLKKKQARYQGVVCAMKEAFGFIERGDVVKEIFFHYSEFKG
                     DLETLQPGDDVEFTIKDRNGKEVATDVRLLPQGTVIFEDISIEHFEGTVTKVIPKVPS
                     KNQNDPLPGRIKVDFVIPKELPFGDKDTKSKVTLLEGDHVRFNISTDRRDKLERATNI
                     EVLSNTFQFTNEAREMGVIAAMRDGFGFIKCVDRDARMFFHFSEILDGNQLHIADEVE
                     FTVVPDMLSAQRNHAIRIKKLPKGTVSFHSHSDHRFLGTVEKEATFSNPKTTSPNKGK
                     DKEAEDGIIAYDDCGVKLTIAFQAKDVEGSTSPQIGDKVEFSISDKQRPGQQIATCVR
                     LLGRNSNSKRLLGYVATLKDNFGFIETANHDKEIFFHYSEFSGDVDSLELGDMVEYSL
                     SKGKGNKVSAEKVNKTHSVNGITEEANPTIYSGKVIRPLRGVDPTQIEYQGMIEIVEE
                     GDMKGEVYPFGIVGMANKGDCLQKGESVKFQLCVLGQNAQTMAYNITPLRRATVECVK
                     DQFGFINYEVGDSKKLFFHVKEVQDGIELQAGDEVEFSVILNQRTGKCSACNVWRVCE
                     GPKAVAAPRPDRLVNRLKNITLDDASAPRLMVLRQPRGPDNSMGFGAERKIRQAGVID
                     "
     exon            521..719
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            720..829
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            830..922
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            923..1020
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1102
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            1103..1231
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            1232..1357
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            1358..1570
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..1711
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            1712..1876
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..1984
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..2160
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            2161..2273
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            2274..2393
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            2394..2572
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            2573..2736
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            2737..2869
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
     exon            2870..4157
                     /gene="Csde1"
                     /gene_synonym="Unr"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctacccgtg cacgcgctcg gagtctgcaa ctctcgcgag agaagcgaga tttattccta
       61 cgtaccgggc cgtgctgctt atggcggcgc tggagagggg gcgctgagct gttgggtatg
      121 aagtgtaacg gaacagactt taccacctga aactgctgct tcaagttcag atcaggcaag
      181 gaacagaccc gcaaccacca acaacaccaa agaagagtac acaagttgaa gacacaacac
      241 ttgatctgaa acaagaagtt tgtgcctact caacagcttt gaaagagcac ttcccaacgc
      301 tgctagtagt ctttgttttc ttcagtgctg tactgtgagg ttgcccggtg cagcagcagt
      361 tgtattcttt attagcttgg tagatcattt cctctcgctc tctttttttt tttttttttt
      421 ttttttaata ctagcaactt tcattctttg gaacttgtgc tgaaaaaaag aagagtcagc
      481 aaatactact gaaagtgcaa tattcgatta tcactgcgag atgagctttg atccaaacct
      541 tctccacaac aatggacaca acgggtaccc caatggtact tctgcagcac tccgtgaaac
      601 tggggttatt gaaaaactgc tgacctctta tggatttatt cagtgttcag aacggcaagc
      661 taggcttttc ttccactgtt cacagtataa tggcaacctc caggacttaa aagtaggaga
      721 tgatgtggaa tttgaagtat catctgaccg gaggactggg aaacctattg ctattaaatt
      781 ggtgaagata aaaccagaaa tacatcctga agaacgaatg aatggacaag ttgtgtgcgc
      841 tgttcctcac aacttagaga gtaaatctcc agctgccccg ggtcagagtc caacagggag
      901 tgtatgctac gaacgtaatg gggaagtatt ttatctgact tacacctctg aagatgtgga
      961 agggaacgtt cagctggaaa ctggagacaa aattaacttt gtaattgata acaataaaca
     1021 cactggtgct gtaagtgctc gtaacattat gctgttgaaa aagaaacaag ctcgctatca
     1081 aggagtagtt tgtgccatga aggaggcgtt tggctttatt gaaagaggtg atgttgtaaa
     1141 agagatattc tttcactata gtgaatttaa aggtgatcta gaaaccctgc agcctggaga
     1201 tgacgtggaa ttcacaatca aggacagaaa tggtaaagaa gttgcaacag atgtcagact
     1261 attgcctcaa ggaacagtca tttttgaaga tatcagcatt gaacattttg aaggaactgt
     1321 aaccaaagtt atcccaaaag tacccagtaa aaaccagaat gacccattgc caggacgaat
     1381 caaagttgac tttgtgattc ctaaagaact tccctttgga gacaaagaca caaaatccaa
     1441 agtgaccctg ctggaaggtg accatgttag gtttaatatt tcaacagacc gacgtgacaa
     1501 attagaacga gcaaccaaca tagaggttct atcaaataca tttcagttca ctaatgaagc
     1561 cagagagatg ggtgtgattg ctgccatgag agatggtttt ggcttcatca agtgtgtgga
     1621 ccgtgatgct cgtatgttct tccacttcag tgagattctc gatgggaacc agctccacat
     1681 tgcagatgaa gtggagttta ctgtggtccc tgatatgctc tctgcccaaa gaaatcatgc
     1741 tattaggatt aaaaaacttc ccaagggcac ggtttcattc cattcccatt cagatcatcg
     1801 ttttctgggc accgtagaaa aagaagccac tttttctaat cctaaaacta caagcccaaa
     1861 taaaggcaaa gacaaggagg cagaagatgg cattattgct tatgatgact gtggggtgaa
     1921 actgactatt gcttttcaag ccaaggatgt ggaaggatct acttctcctc aaataggaga
     1981 taaggttgaa tttagtatta gtgacaaaca gaggcctgga cagcagattg caacttgtgt
     2041 gagactttta ggtcgtaatt ctaattccaa aaggctcttg ggttatgtgg caactctgaa
     2101 agataatttt ggatttattg aaacagctaa tcatgataag gagatatttt tccattatag
     2161 tgagttctct ggtgatgttg atagcctgga actgggagac atggttgaat acagcttgtc
     2221 caaaggcaaa ggcaataaag tcagtgctga gaaagtaaac aaaactcact cagtgaatgg
     2281 catcactgag gaagcaaatc ccaccatcta ctctggtaaa gtcattcgtc ctctgagagg
     2341 cgttgatcca acacagattg aataccaagg aatgattgag attgtggagg agggggatat
     2401 gaaaggtgaa gtgtatcctt ttggcatagt tgggatggcc aacaaagggg attgcctaca
     2461 gaaaggggag agtgttaagt tccagttgtg tgtacttggc caaaatgcac aaactatggc
     2521 ctacaacatc acaccccttc gtagggctac tgtggagtgt gtgaaagatc agtttggctt
     2581 tattaactat gaagtaggag atagcaagaa gctctttttc catgtgaagg aagttcagga
     2641 tggcattgag ctacaggcag gagatgaggt ggaattctca gtgatcctta atcagcgcac
     2701 tgggaaatgt agcgcctgta atgtttggcg agtctgtgaa ggccccaaag ctgttgcagc
     2761 tcctcgacct gatcggttgg ttaatcgctt aaagaacatc accctggatg atgccagtgc
     2821 tccacgtcta atggttcttc gtcagccaag gggaccagat aactcaatgg gatttggtgc
     2881 agaaagaaag atccgtcaag ctggtgtcat tgactaacca cgtccacaaa gcacatcatt
     2941 aatccactat ggtcaagttg gggggattct ggtgaagggt tctgaatatc ttcctcttca
     3001 tccctcccaa aatctggaat acttattcta ttgagctatt acaccagttt taacaccttc
     3061 ctcgtgttat gtttaaagaa aaaataaata aatttaagaa accattttaa aattatgcac
     3121 agttgcagcc tggaaaactt aaggtggcgc cttatagtgt caatttagga gctttatttg
     3181 gtgcatttaa cgcaactggt aattgcaaat tccacttggc ctgtgtaagt gaacaaaaca
     3241 gactgttact ttgttggccc tatgaaattc tgcactctag tcagtatata tactctacct
     3301 tcatgactta atactcagct gcattctttt ccttttttcc ctctgttcat tatgctttaa
     3361 ttctgaggac catatgaagg tagaatatat tacctttaaa aattgcaaaa atttatatag
     3421 caaacgattt tcttaagttg atggccaaat gttaaaatgt tattttcata tcatttataa
     3481 tcttgtcaca atccacttaa cgaagtttga ttacatttca gtgaaaatta tcttccataa
     3541 taggtttttt ttttccttcc tgggatgggg ggcaaataac tttactacaa ttagtatgta
     3601 tggtgcagaa tttcatgcaa atgaagtgtg ccagcagtgt gataatttaa acatatttaa
     3661 acaaaagacg aatgcacaaa attgctgctg cttagatcac tgcagcttct aggacccagt
     3721 ttcttttact gatttaaaaa caaaatgaaa aaaaaataat aaaaaagttg tgcctgaaat
     3781 gaatcctgtt ttttttataa gtagccccct ggttccagtg ccctgttgaa tacaggcact
     3841 tgatccttgg tgcagcttct gttcaacttt gtatcacggg aacggattgg cctgatttct
     3901 tggccttcct cttgaattgg ccccaaacag ggtccctggc aagtggagtg aaggcttttt
     3961 gtctaaagat gacaagggtc agctcagggg ttgtggggga gggcgttttc atcttccccg
     4021 ttgtcacttg aggttttgaa ctctgggtaa agaggccgtt tatctttgta aacacaaaac
     4081 atttttgctt tctccggttt catgttaatg gcgaaagaat ggaagcgaat aaagttttac
     4141 tgatttttga gacacta
//
