LOCUS       NM_001012183            1924 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus crystallin zeta (Cryz), mRNA.
ACCESSION   NM_001012183 XM_342363
VERSION     NM_001012183.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1924)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1924)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   3  (bases 1 to 1924)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (bases 1 to 1924)
  AUTHORS   Fernandez,M.R., Porte,S., Crosas,E., Barbera,N., Farres,J.,
            Biosca,J.A. and Pares,X.
  TITLE     Human and yeast zeta-crystallins bind AU-rich elements in RNA
  JOURNAL   Cell Mol Life Sci 64 (11), 1419-1427 (2007)
   PUBMED   17497241
REFERENCE   5  (bases 1 to 1924)
  AUTHORS   Schroeder,J.M., Liu,W. and Curthoys,N.P.
  TITLE     pH-responsive stabilization of glutamate dehydrogenase mRNA in
            LLC-PK1-F+ cells
  JOURNAL   Am J Physiol Renal Physiol 285 (2), F258-F265 (2003)
   PUBMED   12684230
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC078927.1.
            
            On Aug 31, 2012 this sequence version replaced NM_001012183.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC078927.1, SRR8487227.40641.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132291, SAMD00132292
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1924              BC078927.1         3-1926
FEATURES             Location/Qualifiers
     source          1..1924
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q45"
     gene            1..1924
                     /gene="Cryz"
                     /note="crystallin zeta"
                     /db_xref="GeneID:362061"
                     /db_xref="RGD:1311639"
     exon            1..65
                     /gene="Cryz"
                     /inference="alignment:Splign:2.1.0"
     exon            66..182
                     /gene="Cryz"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..1061
                     /gene="Cryz"
                     /EC_number="1.6.5.5"
                     /note="zeta-crystallin; NADPH:quinone reductase;
                     crystallin, zeta (quinone reductase)"
                     /codon_start=1
                     /product="quinone oxidoreductase"
                     /protein_id="NP_001012183.1"
                     /db_xref="GeneID:362061"
                     /db_xref="RGD:1311639"
                     /translation="MATGQKLMRAIRVFEFGGPEVLKLQSDVVVPAPQSHQVLIKVHA
                     CGVNPVETYIRSGTYSRKPALPYTPGSDVAGIIESVGDGVSAFKKGDRVFCFSTVSGG
                     YAEFALSADNTTYPLPETLDFRQGAALGIPYFTACRALFHSARARAGESVLVHGASGG
                     VGLATCQIARAHGLKVLGTAGSEEGKKLVLQNGAHEVFNHKEANYIDKIKTSAGDKGV
                     DVIIEMLANKNLSNDLKLLSCGGRVIVVGCRGSIEINPRDTMAKETSIIGVSLFSSTK
                     EEFQQFAGILQAGIEKGWVKPVIGSEYPLEKAAQAHEDIIHSSGKMGKMILLL"
     exon            183..335
                     /gene="Cryz"
                     /inference="alignment:Splign:2.1.0"
     exon            336..499
                     /gene="Cryz"
                     /inference="alignment:Splign:2.1.0"
     exon            500..551
                     /gene="Cryz"
                     /inference="alignment:Splign:2.1.0"
     exon            552..701
                     /gene="Cryz"
                     /inference="alignment:Splign:2.1.0"
     exon            702..803
                     /gene="Cryz"
                     /inference="alignment:Splign:2.1.0"
     exon            804..899
                     /gene="Cryz"
                     /inference="alignment:Splign:2.1.0"
     exon            900..1900
                     /gene="Cryz"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgcccatct cttttcctaa ggaacttctg gagtttagga ggtttgattc ctactgtaga
       61 ggaggatcac catggcaact ggacagaagt tgatgagggc tattcgagtg tttgaatttg
      121 gtggaccgga agtgctgaag ctccagtctg atgtggtagt tcctgctcca cagagccatc
      181 aggtcctaat caaagtccat gcctgcggcg tcaaccccgt agagacatac attcgctccg
      241 ggacctacag tcggaagcct gccttaccct acactccagg cagcgatgtg gctgggatca
      301 tagaatctgt tggagatggt gtgtctgctt tcaagaaggg cgaccgggtc ttctgcttta
      361 gcacagtctc tggtggctac gcagaattcg ctctttcggc agataacacc acctaccccc
      421 tgcccgagac actggacttc aggcaggggg ctgccctggg gattccgtac ttcacggcct
      481 gccgagctct gttccacagt gcccgtgctc gagctgggga aagcgttctt gttcacgggg
      541 ccagcggagg agttggatta gctacatgcc agattgccag agctcatggc ttaaaggttt
      601 tgggcacagc tggttctgag gaaggaaaaa agcttgttct gcaaaacgga gcccacgaag
      661 tgtttaatca caaagaagcc aactatattg ataaaatcaa gacgtctgct ggtgacaagg
      721 gcgttgatgt gattattgag atgctggcga acaagaacct cagcaatgac ctgaagctcc
      781 tgtcctgcgg agggcgggtc attgtcgttg gctgtagagg ttccattgag ataaacccaa
      841 gggacaccat ggccaaagag acgagtataa tcggagtctc tctcttttca tccaccaagg
      901 aggaattcca gcaattcgca ggcatcctcc aagcaggaat agaaaaaggt tgggtgaaac
      961 ctgtgatagg ttctgagtat ccactggaga aggcggccca ggcccatgaa gacatcattc
     1021 acagcagtgg gaagatgggg aaaatgattc tcctcttatg agaccagctg ttcctgggga
     1081 tgcctgtgtc agtgggactc ctccttctcc aagtcgctgc tgcaccatct ttaatcagtg
     1141 ttcatttgat tgaggttcat gtattaaaaa cacagcttta gggaggagac ccagtggagt
     1201 gatgtgtcca gtgtggtact ggcatgcatc acaaaactct tgttcctttt tcttcgtttt
     1261 cattctttgg ttggatattt ttgttttatt tttgagacag aatcattctc catagttcat
     1321 gctggccttg agctcatggt ggtctttctg cctcagcttg gaagtgctgg gattttagtc
     1381 atgcactatc acacacagat tcatctcaca ccttcttgtc tgattagctt cattcatacc
     1441 tttgaataaa atgtacaagt tcaaaatagt cctctactga tcgcccctgg cttccaagcc
     1501 tgctcccctt taggtagtca cctgacccct cagccatggc tgccgtgggc cctgaaggat
     1561 ttctggactg aaaaacatgc ttttaaaact aatgtcatct cagtctgtaa gccctgggga
     1621 agggcaaaaa tgagcaacac ctacgggaaa acctaccagt cagttttcct cacatttccg
     1681 agaatatcag aatactcact gcatgctggt caccaaccac ccctgctttg ggaggtcagc
     1741 aacctgatcc tgagtcagcg gcattcagta ccatcaccca ttaaatgctt catggtcgtt
     1801 tacagttatt ggtatatatg acacgtctca tagttttact taaaattgta agttcacaaa
     1861 tttagcactt taaaaactgt ctgctttggt ttgcatagta aaaaaaaaaa aaaaaaaaaa
     1921 aaaa
//
