LOCUS       NM_001109557             684 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus crystallin, gamma F (Crygf), mRNA.
ACCESSION   NM_001109557 NM_001085380 XM_001072649
VERSION     NM_001109557.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 684)
  AUTHORS   Kim,I., Saito,T., Fujii,N., Kanamoto,T., Chatake,T. and Fujii,N.
  TITLE     Site specific oxidation of amino acid residues in rat lens
            gamma-crystallin induced by low-dose gamma-irradiation
  JOURNAL   Biochem Biophys Res Commun 466 (4), 622-628 (2015)
   PUBMED   26385181
  REMARK    GeneRIF: Specific oxidation sites of methionine, cysteine and
            tryptophan in water-soluble and -insoluble gammaE and
            gammaF-crystallin were determined by one-shot analysis after
            low-dose gamma-irradiation.
REFERENCE   2  (bases 1 to 684)
  AUTHORS   Lengler,J., Krausz,E., Tomarev,S., Prescott,A., Quinlan,R.A. and
            Graw,J.
  TITLE     Antagonistic action of Six3 and Prox1 at the gamma-crystallin
            promoter
  JOURNAL   Nucleic Acids Res 29 (2), 515-526 (2001)
   PUBMED   11139622
REFERENCE   3  (bases 1 to 684)
  AUTHORS   Voorter,C.E., De Haard-Hoekman,W.A., Hermans,M.M., Bloemendal,H.
            and De Jong,W.W.
  TITLE     Differential synthesis of crystallins in the developing rat eye
            lens
  JOURNAL   Exp Eye Res 50 (4), 429-437 (1990)
   PUBMED   2338125
REFERENCE   4  (bases 1 to 684)
  AUTHORS   den Dunnen,J.T., van Neck,J.W., Cremers,F.P., Lubsen,N.H. and
            Schoenmakers,J.G.
  TITLE     Nucleotide sequence of the rat gamma-crystallin gene region and
            comparison with an orthologous human region
  JOURNAL   Gene 78 (2), 201-213 (1989)
   PUBMED   2777080
REFERENCE   5  (bases 1 to 684)
  AUTHORS   den Dunnen,J.T., Moormann,R.J., Lubsen,N.H. and Schoenmakers,J.G.
  TITLE     Concerted and divergent evolution within the rat gamma-crystallin
            gene family
  JOURNAL   J Mol Biol 189 (1), 37-46 (1986)
   PUBMED   3783678
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474044.2.
            
            On or before May 29, 2008 this sequence version replaced
            NM_001085380.1, XM_001072649.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BF553419.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..684
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q32"
     gene            1..684
                     /gene="Crygf"
                     /gene_synonym="Cryg6; Len"
                     /note="crystallin, gamma F"
                     /db_xref="GeneID:689947"
                     /db_xref="RGD:1586353"
     exon            1..104
                     /gene="Crygf"
                     /gene_synonym="Cryg6; Len"
                     /inference="alignment:Splign:2.1.0"
     CDS             96..620
                     /gene="Crygf"
                     /gene_synonym="Cryg6; Len"
                     /note="crystallin, gamma polypeptide 6;
                     gamma-F-crystallin; gamma-crystallin 4-1"
                     /codon_start=1
                     /product="gamma-crystallin F"
                     /protein_id="NP_001103027.1"
                     /db_xref="GeneID:689947"
                     /db_xref="RGD:1586353"
                     /translation="MGKITFYEDRGFQGRHYECSTDHSNLQPYFSRCNSVRVDSGCWM
                     LYEQPNFTGCQYFLRRGEYPDYQQWMGFSDSVRSCHLIPHSSSHRIRIYEREDYRGQM
                     VEITDDCPHLQDRFHFSDFHSFHVIEGYWVLYEMPNYRGRQYLLRPREYRRYHDWGAM
                     NARVGSLRRIMDYY"
     exon            105..347
                     /gene="Crygf"
                     /gene_synonym="Cryg6; Len"
                     /inference="alignment:Splign:2.1.0"
     exon            348..684
                     /gene="Crygf"
                     /gene_synonym="Cryg6; Len"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttcctgcca acgcagcaga cctcctgcta tatatataga ccctgctccc agccctacac
       61 aaccaacagc accatcccat ccgcaaacac cagccatggg aaagatcacc ttctatgagg
      121 accgaggctt ccagggccgc cactatgagt gcagcacaga ccactccaac ctgcagccct
      181 acttcagccg ctgcaactct gtgcgcgtgg acagtggctg ctggatgctc tatgagcagc
      241 ccaacttcac aggctgccag tatttccttc gtcgcgggga gtaccctgac taccagcagt
      301 ggatgggttt cagcgactct gtccgctcct gccacctcat cccccactcc agctctcaca
      361 gaatcaggat ctacgagcga gaggactaca gaggccagat ggtggagatc acagacgact
      421 gcccccacct gcaggaccgc ttccacttca gtgacttcca ctccttccac gtgatagagg
      481 gctactgggt cctctacgag atgcccaact accgggggcg gcagtacctg ctgaggccca
      541 gggaatacag gcgctaccac gactggggcg ccatgaatgc cagggtgggc tctctgagga
      601 gaatcatgga ttactattga attgtcttac tctgcccttt catcatttgg aagttaataa
      661 aatatttcct gtgtgttcca tgca
//
