LOCUS       NM_001080936             618 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus crystallin, gamma A (Cryga), mRNA.
ACCESSION   NM_001080936 XM_001066957 XM_001067011
VERSION     NM_001080936.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 618)
  AUTHORS   Graw,J., Neuhauser-Klaus,A., Klopp,N., Selby,P.B., Loster,J. and
            Favor,J.
  TITLE     Genetic and allelic heterogeneity of Cryg mutations in eight
            distinct forms of dominant cataract in the mouse
  JOURNAL   Invest Ophthalmol Vis Sci 45 (4), 1202-1213 (2004)
   PUBMED   15037589
REFERENCE   2  (bases 1 to 618)
  AUTHORS   Everett,C.A., Glenister,P.H., Taylor,D.M., Lyon,M.F.,
            Kratochvilova-Loester,J. and Favor,J.
  TITLE     Mapping of six dominant cataract genes in the mouse
  JOURNAL   Genomics 20 (3), 429-434 (1994)
   PUBMED   8034315
REFERENCE   3  (bases 1 to 618)
  AUTHORS   Voorter,C.E., De Haard-Hoekman,W.A., Hermans,M.M., Bloemendal,H.
            and De Jong,W.W.
  TITLE     Differential synthesis of crystallins in the developing rat eye
            lens
  JOURNAL   Exp Eye Res 50 (4), 429-437 (1990)
   PUBMED   2338125
REFERENCE   4  (bases 1 to 618)
  AUTHORS   den Dunnen,J.T., van Neck,J.W., Cremers,F.P., Lubsen,N.H. and
            Schoenmakers,J.G.
  TITLE     Nucleotide sequence of the rat gamma-crystallin gene region and
            comparison with an orthologous human region
  JOURNAL   Gene 78 (2), 201-213 (1989)
   PUBMED   2777080
REFERENCE   5  (bases 1 to 618)
  AUTHORS   den Dunnen,J.T., Moormann,R.J., Lubsen,N.H. and Schoenmakers,J.G.
  TITLE     Concerted and divergent evolution within the rat gamma-crystallin
            gene family
  JOURNAL   J Mol Biol 189 (1), 37-46 (1986)
   PUBMED   3783678
REFERENCE   6  (bases 1 to 618)
  AUTHORS   Favor,J.
  TITLE     Characterization of dominant cataract mutations in mice:
            penetrance, fertility and homozygous viability of mutations
            recovered after 250 mg/kg ethylnitrosourea paternal treatment
  JOURNAL   Genet Res 44 (2), 183-197 (1984)
   PUBMED   6510713
REFERENCE   7  (bases 1 to 618)
  AUTHORS   Favor,J.
  TITLE     A comparison of the dominant cataract and recessive specific-locus
            mutation rates induced by treatment of male mice with
            ethylnitrosourea
  JOURNAL   Mutat Res 110 (2), 367-382 (1983)
   PUBMED   6877261
REFERENCE   8  (bases 1 to 618)
  AUTHORS   Ehling,U.H., Favor,J., Kratochvilova,J. and Neuhauser-Klaus,A.
  TITLE     Dominant cataract mutations and specific-locus mutations in mice
            induced by radiation or ethylnitrosourea
  JOURNAL   Mutat Res 92 (1-2), 181-192 (1982)
   PUBMED   7088001
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Nov 10, 2022 this sequence version replaced NM_001080936.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN06680452,
                              SAMN16676807 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on computational evidence
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                JAXUCZ010000009.1  73978341-73978382   c
            43-285              JAXUCZ010000009.1  73977998-73978240   c
            286-618             JAXUCZ010000009.1  73975914-73976246   c
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q32"
     gene            1..618
                     /gene="Cryga"
                     /note="crystallin, gamma A"
                     /db_xref="GeneID:684028"
                     /db_xref="RGD:1595217"
     exon            1..42
                     /gene="Cryga"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..558
                     /gene="Cryga"
                     /note="CRY-gamma-A; gamma-A-crystallin; gamma-crystallin
                     1-1"
                     /codon_start=1
                     /product="gamma-crystallin A"
                     /protein_id="NP_001074405.1"
                     /db_xref="GeneID:684028"
                     /db_xref="RGD:1595217"
                     /translation="MGKITFYEDRGFQGRCYECSSDCPNLQTYFSRCNSIRVDSGCWM
                     LYERPNYQGYQYFLRRGDYPDYQQWMGFSDSIRSCRSIPYTSSHRIRLYERDDYRGLV
                     SELTEDCSCIHDRFRLNEIYSMHVLEGSWVLYEMPNYRGRQYLLRPGDYRRYHDWGAM
                     DAKVGSLRRVMDLY"
     exon            43..285
                     /gene="Cryga"
                     /inference="alignment:Splign:2.1.0"
     exon            286..618
                     /gene="Cryga"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acactcaaca ctgaccattt gctgtcaaca acgatgggaa agatcacctt ctacgaggac
       61 cgaggcttcc agggccgctg ctatgagtgc agcagcgact gccccaacct gcagacctac
      121 ttcagccgct gcaactccat ccgcgtggac agtggctgct ggatgctcta tgagcgaccc
      181 aactaccagg gctaccagta cttcctgcga cgcggggact accctgacta ccagcagtgg
      241 atgggtttca gcgactccat tcgctcctgc cgttccattc cctataccag ctctcacagg
      301 ataaggctgt acgagagaga tgactaccgg ggccttgtgt ctgagctcac ggaagactgt
      361 tcctgcatcc acgaccgctt ccgcctcaac gagatctact ccatgcatgt gctagaaggc
      421 agctgggtcc tctatgagat gcccaactac cgaggccgcc agtacctgct caggcctgga
      481 gactacaggc gctaccacga ctggggcgcc atggatgcca aagtcggctc tctgagacgg
      541 gtcatggatt tgtactaagc cccattttgc ttgttacaac acacacatgc aataaatata
      601 caacttgtgt tcctggca
//
