LOCUS       NM_031690                747 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus crystallin, beta B3 (Crybb3), mRNA.
ACCESSION   NM_031690
VERSION     NM_031690.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 747)
  AUTHORS   Lampi,K.J., Shih,M., Ueda,Y., Shearer,T.R. and David,L.L.
  TITLE     Lens proteomics: analysis of rat crystallin sequences and
            two-dimensional electrophoresis map
  JOURNAL   Invest Ophthalmol Vis Sci 43 (1), 216-224 (2002)
   PUBMED   11773034
REFERENCE   2  (bases 1 to 747)
  AUTHORS   David,L.L. and Shearer,T.R.
  TITLE     Beta-crystallins insolubilized by calpain II in vitro contain
            cleavage sites similar to beta-crystallins insolubilized during
            cataract
  JOURNAL   FEBS Lett 324 (3), 265-270 (1993)
   PUBMED   8405363
REFERENCE   3  (bases 1 to 747)
  AUTHORS   den Dunnen,J.T., Moormann,R.J. and Schoenmakers,J.G.
  TITLE     Rat lens beta-crystallins are internally duplicated and homologous
            to gamma-crystallins
  JOURNAL   Biochim Biophys Acta 824 (4), 295-303 (1985)
   PUBMED   3879970
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X05899.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X05899.1, AF287304.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680452 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..747
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..747
                     /gene="Crybb3"
                     /note="crystallin, beta B3"
                     /db_xref="GeneID:64349"
                     /db_xref="RGD:61980"
     exon            1..116
                     /gene="Crybb3"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..677
                     /gene="Crybb3"
                     /note="beta-B3 crystallin"
                     /codon_start=1
                     /product="beta-crystallin B3"
                     /protein_id="NP_113878.1"
                     /db_xref="GeneID:64349"
                     /db_xref="RGD:61980"
                     /translation="MAEQHGAPEQAAANKSHGGLGGSYKVTVYELENFQGKRCELSAE
                     CPNLTESLLQKVGSIQVESGPWLAFERRAFRGEQFVLEKGDYPAWDAWSSSRRSDILL
                     SLRPLHIDGPDHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASIRVINGTWVG
                     YEFPGYRGRQYVFERGEFRHWNEWDANQPQLQSVRRIRDQKWHKRGCFLSS"
     exon            117..235
                     /gene="Crybb3"
                     /inference="alignment:Splign:2.1.0"
     exon            236..368
                     /gene="Crybb3"
                     /inference="alignment:Splign:2.1.0"
     exon            369..511
                     /gene="Crybb3"
                     /inference="alignment:Splign:2.1.0"
     exon            512..747
                     /gene="Crybb3"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      747
                     /gene="Crybb3"
                     /note="polyA site"
ORIGIN      
        1 ctggttctcc tccagtttga ggcggaagtg tccccggaga catggcagag cagcacggag
       61 cacctgagca ggctgcagct aacaagagcc acggaggcct tgggggcagc tacaaggtga
      121 cggtgtacga gttagagaac ttccagggca agcgatgcga gctctcggct gagtgtccca
      181 acctcactga aagcctgctg cagaaggtgg gctctatcca agtggaatct ggaccgtggc
      241 tggcgttcga gcgcagggct tttcgtgggg agcagtttgt cctggagaag ggggactacc
      301 ccgcgtggga tgcctggtcc agcagccggc gtagtgacat tctcctgtcc ctccggcctt
      361 tgcacattga tggcccagac cacaagctgc acctctttga gaacccagcc ttcagtgggc
      421 gcaagatgga gatcgtagat gatgatgtgc ccagcctgtg ggcccatggc ttccaggacc
      481 gtgtggccag catccgagtc atcaacggga cgtgggtggg ctacgagttc cccggctacc
      541 gcgggcgcca gtacgtgttc gagcggggcg agttccgcca ttggaacgag tgggacgcca
      601 accagccgca gctgcagtcg gtgcgccgca tccgcgacca gaagtggcac aagcgcggct
      661 gcttcctgag cagctgagga cccaggtccc aggagccaac gtctgtgtcc cctcctgtac
      721 ctgctcaata aagcccatca gccacgc
//
