LOCUS       NP_775163                197 aa            linear   ROD 24-JUL-2024
DEFINITION  beta-crystallin A2 [Rattus norvegicus].
ACCESSION   NP_775163
VERSION     NP_775163.1
DBSOURCE    REFSEQ: accession NM_173140.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 197)
  AUTHORS   Puk,O., Ahmad,N., Wagner,S., Hrabe de Angelis,M. and Graw,J.
  TITLE     First mutation in the betaA2-crystallin encoding gene is associated
            with small lenses and age-related cataracts
  JOURNAL   Invest Ophthalmol Vis Sci 52 (5), 2571-2576 (2011)
   PUBMED   21212184
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 197)
  AUTHORS   Sergeev,Y.V., Hejtmancik,J.F. and Wingfield,P.T.
  TITLE     Energetics of domain-domain interactions and entropy driven
            association of beta-crystallins
  JOURNAL   Biochemistry 43 (2), 415-424 (2004)
   PUBMED   14717595
  REMARK    Erratum:[Biochemistry. 2007 Feb 6;46(5):1456]
REFERENCE   3  (residues 1 to 197)
  AUTHORS   Hulsebos,T.J., Cerosaletti,K.M., Fournier,R.E., Sinke,R.J.,
            Rocchi,M., Marzella,R., Jenkins,N.A., Gilbert,D.J. and
            Copeland,N.G.
  TITLE     Identification of the human beta A2 crystallin gene (CRYBA2):
            localization of the gene on human chromosome 2 and of the
            homologous gene on mouse chromosome 1
  JOURNAL   Genomics 28 (3), 543-548 (1995)
   PUBMED   7490092
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY158891.1, SRR26360194.1629368.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN17050745, SAMN17050746
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..197
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q33"
     Protein         1..197
                     /product="beta-crystallin A2"
                     /note="betaA2-crystallin"
                     /calculated_mol_wt=22115
     Region          14..98
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     Region          107..195
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     CDS             1..197
                     /gene="Cryba2"
                     /coded_by="NM_173140.2:45..638"
                     /db_xref="GeneID:286925"
                     /db_xref="RGD:628768"
ORIGIN      
        1 mssapapgpa pacltlwdee dfqgrrcrll sdcanvcerg alrrvrsvkv engawvafey
       61 pdfqgqqfil ekgdypcwsa wsgssghhsn qllsfrpvlc anhsdsrvtl fegenfqgck
      121 felsddypsl psmgwtskdv gslkvssgaw vayqypgyrg yqyvlerdrh sgefrtyndf
      181 gtqahtgqlq sirrvqh
//
