LOCUS       NM_001401203            1710 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus cartilage associated protein (Crtap), transcript
            variant 1, mRNA.
ACCESSION   NM_001401203 XM_006243992
VERSION     NM_001401203.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1710)
  AUTHORS   Barnes,A.M., Carter,E.M., Cabral,W.A., Weis,M., Chang,W.,
            Makareeva,E., Leikin,S., Rotimi,C.N., Eyre,D.R., Raggio,C.L. and
            Marini,J.C.
  TITLE     Lack of cyclophilin B in osteogenesis imperfecta with normal
            collagen folding
  JOURNAL   N Engl J Med 362 (6), 521-528 (2010)
   PUBMED   20089953
REFERENCE   2  (bases 1 to 1710)
  AUTHORS   Chang,W., Barnes,A.M., Cabral,W.A., Bodurtha,J.N. and Marini,J.C.
  TITLE     Prolyl 3-hydroxylase 1 and CRTAP are mutually stabilizing in the
            endoplasmic reticulum collagen prolyl 3-hydroxylation complex
  JOURNAL   Hum Mol Genet 19 (2), 223-234 (2010)
   PUBMED   19846465
REFERENCE   3  (bases 1 to 1710)
  AUTHORS   Morello,R., Bertin,T.K., Chen,Y., Hicks,J., Tonachini,L.,
            Monticone,M., Castagnola,P., Rauch,F., Glorieux,F.H., Vranka,J.,
            Bachinger,H.P., Pace,J.M., Schwarze,U., Byers,P.H., Weis,M.,
            Fernandes,R.J., Eyre,D.R., Yao,Z., Boyce,B.F. and Lee,B.
  TITLE     CRTAP is required for prolyl 3- hydroxylation and mutations cause
            recessive osteogenesis imperfecta
  JOURNAL   Cell 127 (2), 291-304 (2006)
   PUBMED   17055431
REFERENCE   4  (bases 1 to 1710)
  AUTHORS   Pang,A.L., Taylor,H.C., Johnson,W., Alexander,S., Chen,Y., Su,Y.A.,
            Li,X., Ravindranath,N., Dym,M., Rennert,O.M. and Chan,W.Y.
  TITLE     Identification of differentially expressed genes in mouse
            spermatogenesis
  JOURNAL   J Androl 24 (6), 899-911 (2003)
   PUBMED   14581517
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Feb 4, 2022 this sequence version replaced XM_006243992.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22399484.654287.1,
                                           SRR26643291.24471.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840105,
                                           SAMN12840111 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-553               JAXUCZ010000008.1  122945291-122945843 c
            554-703             JAXUCZ010000008.1  122941914-122942063 c
            704-875             JAXUCZ010000008.1  122934371-122934542 c
            876-1004            JAXUCZ010000008.1  122931886-122932014 c
            1005-1150           JAXUCZ010000008.1  122930767-122930912 c
            1151-1234           JAXUCZ010000008.1  122928975-122929058 c
            1235-1710           JAXUCZ010000008.1  122926117-122926592 c
FEATURES             Location/Qualifiers
     source          1..1710
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..1710
                     /gene="Crtap"
                     /gene_synonym="Crtapl1; RGD1565180"
                     /note="cartilage associated protein"
                     /db_xref="GeneID:363158"
                     /db_xref="RGD:1565180"
     exon            1..553
                     /gene="Crtap"
                     /gene_synonym="Crtapl1; RGD1565180"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..1288
                     /gene="Crtap"
                     /gene_synonym="Crtapl1; RGD1565180"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; cartilage-associated protein-like; cartilage
                     associated protein-like 1"
                     /codon_start=1
                     /product="cartilage-associated protein isoform 1
                     precursor"
                     /protein_id="NP_001388132.1"
                     /db_xref="GeneID:363158"
                     /db_xref="RGD:1565180"
                     /translation="MGPRSPAAALLVLLCAGCVLSPGRAQYERYSFRSFPRDELMPLE
                     SAYRHALDQYSGEHWAESVGYLEVSLRLHRLLRDSEAFCHRNCSAATPAPAPSGPASP
                     ASHRELRLFGGVLRRAQCLKRCKQGLPAFRQSQPSRAVLADFQQREPYKFLQFAYFKA
                     NDLPKAIAAAHTYLLKHPEDEMMKRNMEYYKSLPGAEDHIKDLETKSYESLFVRAVRA
                     YNGENWRTSISDMELALPDFFKAFYECLAACEGSREIKDFKDFYLSIADHYVEVLECK
                     IHCEETLTPVIGGYPVEKFVATIYHYLQFAYYKLNDLKNAAPCAVSYLLFDPNDKVMQ
                     QNLVYYQYHRDKWGLSDEHFQPRLEAVQFFNVTTLQKELYDFAQEHLMDDDEGEVVEY
                     VDDLLEMEESA"
     exon            554..703
                     /gene="Crtap"
                     /gene_synonym="Crtapl1; RGD1565180"
                     /inference="alignment:Splign:2.1.0"
     exon            704..875
                     /gene="Crtap"
                     /gene_synonym="Crtapl1; RGD1565180"
                     /inference="alignment:Splign:2.1.0"
     exon            876..1004
                     /gene="Crtap"
                     /gene_synonym="Crtapl1; RGD1565180"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1150
                     /gene="Crtap"
                     /gene_synonym="Crtapl1; RGD1565180"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1234
                     /gene="Crtap"
                     /gene_synonym="Crtapl1; RGD1565180"
                     /inference="alignment:Splign:2.1.0"
     exon            1235..1710
                     /gene="Crtap"
                     /gene_synonym="Crtapl1; RGD1565180"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgtccccgc ctcccctcct aggcctgccg cgtagcgcat cctgggctct gggctcgggt
       61 tagcgggcca cgcgcgatgg ggccccgcag ccctgcggcc gcgttgctgg tgctgctgtg
      121 tgctgggtgc gtgctgtccc ccgggcgcgc gcagtatgag cgctacagct tccgcagctt
      181 cccccgggac gagctgatgc cgctcgagtc ggcctaccgc cacgcgctcg accagtacag
      241 cggcgagcac tgggccgaga gcgtgggcta cctagaggtg agcctgcggc tgcaccgtct
      301 gctgcgcgac agcgaggcct tctgccaccg caactgcagc gcggccacgc ctgcgcccgc
      361 gccctctggt cccgccagcc ccgccagcca cagggagctg cgcctctttg gcggcgtgct
      421 gcgccgcgcg cagtgcctca agcgctgcaa gcagggcctg cccgccttcc gccagtcgca
      481 gcccagccgc gcggtgctgg ctgactttca gcagcgcgag ccctacaaat tcctgcagtt
      541 cgcctacttc aaggccaatg acctcccgaa ggccatcgct gccgctcaca cctaccttct
      601 gaaacatcct gaggacgaga tgatgaagag aaacatggag tattacaaga gcttgcctgg
      661 agctgaggac cacattaaag acttggaaac caagtcctac gagagcctgt ttgtccgtgc
      721 ggtgcgggcc tacaacgggg agaattggag gacatccatt tccgacatgg agctggcact
      781 tcctgacttc ttcaaggctt tttatgagtg cctggctgcc tgtgaggggt cgagggagat
      841 taaggacttc aaggacttct acctgtccat agcagatcac tatgtggaag ttctggagtg
      901 taagattcat tgtgaggaga ccctcacccc agtcatagga ggttaccccg tggagaaatt
      961 tgtggctacc atctaccact atttgcagtt tgcttactac aagttgaacg atctgaagaa
     1021 cgcagccccg tgtgccgtca gctacctgct ctttgacccg aatgacaagg tcatgcaaca
     1081 gaatctcgtc tattatcagt accaccggga caagtggggc ctctcagatg agcacttcca
     1141 gcccagactg gaggcagttc agttctttaa tgtgactaca ctccagaaag aactgtatga
     1201 cttcgctcag gaacacctca tggacgacga tgagggagag gttgtggagt atgtggatga
     1261 cctgttggag atggaagagt ctgcttagtc cacagcagct aagggacttc tcttccgagt
     1321 tcctccttct tcaagtgcct gggttgttga tacctcacag ctttcccttc ttaaagtaag
     1381 ggggaagcca ccgtctctcc cgaccaaggt caaacctgcc ttccccacgg tcacacccgt
     1441 ccactcccct ttccacctgc cttctctgta ttcacactcg tcttcatggt tacacgtcat
     1501 cacgcctgtc tttcccctca catgtgcctt cccgttgtcc agtccagccc tccccatggt
     1561 cacacttgtc tcccctctgg tcccatgtgt ctcccccgtg ttcagagaga cagtcttctg
     1621 tggtctgctt ttttaatccc tgaagaaaat cagtattatt ttttaagtaa gaaaaacact
     1681 aaaagatgat aaatatattt gaagaattcc
//
