LOCUS       NM_001415935            6614 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus ciliary rootlet coiled-coil, rootletin (Crocc),
            mRNA.
ACCESSION   NM_001415935
VERSION     NM_001415935.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6614)
  AUTHORS   Mahuzier,A., Shihavuddin,A., Fournier,C., Lansade,P., Faucourt,M.,
            Menezes,N., Meunier,A., Garfa-Traore,M., Carlier,M.F.,
            Voituriez,R., Genovesio,A., Spassky,N. and Delgehyr,N.
  TITLE     Ependymal cilia beating induces an actin network to protect
            centrioles against shear stress
  JOURNAL   Nat Commun 9 (1), 2279 (2018)
   PUBMED   29891944
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6614)
  AUTHORS   Nechipurenko,I.V., Olivier-Mason,A., Kazatskaya,A., Kennedy,J.,
            McLachlan,I.G., Heiman,M.G., Blacque,O.E. and Sengupta,P.
  TITLE     A Conserved Role for Girdin in Basal Body Positioning and
            Ciliogenesis
  JOURNAL   Dev Cell 38 (5), 493-506 (2016)
   PUBMED   27623382
REFERENCE   3  (bases 1 to 6614)
  AUTHORS   Fang,G., Zhang,D., Yin,H., Zheng,L., Bi,X. and Yuan,L.
  TITLE     Centlein mediates an interaction between C-Nap1 and Cep68 to
            maintain centrosome cohesion
  JOURNAL   J Cell Sci 127 (Pt 8), 1631-1639 (2014)
   PUBMED   24554434
REFERENCE   4  (bases 1 to 6614)
  AUTHORS   Kobayashi,T., Kim,S., Lin,Y.C., Inoue,T. and Dynlacht,B.D.
  TITLE     The CP110-interacting proteins Talpid3 and Cep290 play overlapping
            and distinct roles in cilia assembly
  JOURNAL   J Cell Biol 204 (2), 215-229 (2014)
   PUBMED   24421332
REFERENCE   5  (bases 1 to 6614)
  AUTHORS   Gilliam,J.C., Chang,J.T., Sandoval,I.M., Zhang,Y., Li,T.,
            Pittler,S.J., Chiu,W. and Wensel,T.G.
  TITLE     Three-dimensional architecture of the rod sensory cilium and its
            disruption in retinal neurodegeneration
  JOURNAL   Cell 151 (5), 1029-1041 (2012)
   PUBMED   23178122
REFERENCE   6  (bases 1 to 6614)
  AUTHORS   Yang,J., Adamian,M. and Li,T.
  TITLE     Rootletin interacts with C-Nap1 and may function as a physical
            linker between the pair of centrioles/basal bodies in cells
  JOURNAL   Mol Biol Cell 17 (2), 1033-1040 (2006)
   PUBMED   16339073
REFERENCE   7  (bases 1 to 6614)
  AUTHORS   Bahe,S., Stierhof,Y.D., Wilkinson,C.J., Leiss,F. and Nigg,E.A.
  TITLE     Rootletin forms centriole-associated filaments and functions in
            centrosome cohesion
  JOURNAL   J Cell Biol 171 (1), 27-33 (2005)
   PUBMED   16203858
REFERENCE   8  (bases 1 to 6614)
  AUTHORS   Yang,J. and Li,T.
  TITLE     The ciliary rootlet interacts with kinesin light chains and may
            provide a scaffold for kinesin-1 vesicular cargos
  JOURNAL   Exp Cell Res 309 (2), 379-389 (2005)
   PUBMED   16018997
REFERENCE   9  (bases 1 to 6614)
  AUTHORS   Yang,J., Gao,J., Adamian,M., Wen,X.H., Pawlyk,B., Zhang,L.,
            Sanderson,M.J., Zuo,J., Makino,C.L. and Li,T.
  TITLE     The ciliary rootlet maintains long-term stability of sensory cilia
  JOURNAL   Mol Cell Biol 25 (10), 4129-4137 (2005)
   PUBMED   15870283
REFERENCE   10 (bases 1 to 6614)
  AUTHORS   Yang,J., Liu,X., Yue,G., Adamian,M., Bulgakov,O. and Li,T.
  TITLE     Rootletin, a novel coiled-coil protein, is a structural component
            of the ciliary rootlet
  JOURNAL   J Cell Biol 159 (3), 431-440 (2002)
   PUBMED   12427867
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-189               JAXUCZ010000005.1  158640050-158640238 c
            190-331             JAXUCZ010000005.1  158639497-158639638 c
            332-486             JAXUCZ010000005.1  158637791-158637945 c
            487-672             JAXUCZ010000005.1  158633439-158633624 c
            673-756             JAXUCZ010000005.1  158633268-158633351 c
            757-818             JAXUCZ010000005.1  158633134-158633195 c
            819-984             JAXUCZ010000005.1  158632883-158633048 c
            985-1091            JAXUCZ010000005.1  158632429-158632535 c
            1092-1328           JAXUCZ010000005.1  158630078-158630314 c
            1329-1425           JAXUCZ010000005.1  158629614-158629710 c
            1426-1509           JAXUCZ010000005.1  158629041-158629124 c
            1510-1743           JAXUCZ010000005.1  158628485-158628718 c
            1744-1943           JAXUCZ010000005.1  158627850-158628049 c
            1944-2126           JAXUCZ010000005.1  158625904-158626086 c
            2127-2271           JAXUCZ010000005.1  158624759-158624903 c
            2272-2418           JAXUCZ010000005.1  158623854-158624000 c
            2419-2649           JAXUCZ010000005.1  158623319-158623549 c
            2650-2843           JAXUCZ010000005.1  158622467-158622660 c
            2844-2971           JAXUCZ010000005.1  158622079-158622206 c
            2972-3141           JAXUCZ010000005.1  158620930-158621099 c
            3142-3321           JAXUCZ010000005.1  158619036-158619215 c
            3322-3456           JAXUCZ010000005.1  158618333-158618467 c
            3457-3600           JAXUCZ010000005.1  158617882-158618025 c
            3601-3839           JAXUCZ010000005.1  158617046-158617284 c
            3840-3999           JAXUCZ010000005.1  158616253-158616412 c
            4000-4167           JAXUCZ010000005.1  158614038-158614205 c
            4168-4516           JAXUCZ010000005.1  158612917-158613265 c
            4517-4686           JAXUCZ010000005.1  158609501-158609670 c
            4687-4807           JAXUCZ010000005.1  158609277-158609397 c
            4808-4971           JAXUCZ010000005.1  158608842-158609005 c
            4972-5187           JAXUCZ010000005.1  158607500-158607715 c
            5188-5412           JAXUCZ010000005.1  158607103-158607327 c
            5413-5562           JAXUCZ010000005.1  158606568-158606717 c
            5563-5763           JAXUCZ010000005.1  158606090-158606290 c
            5764-5895           JAXUCZ010000005.1  158605859-158605990 c
            5896-6075           JAXUCZ010000005.1  158605230-158605409 c
            6076-6614           JAXUCZ010000005.1  158603979-158604517 c
FEATURES             Location/Qualifiers
     source          1..6614
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..6614
                     /gene="Crocc"
                     /note="ciliary rootlet coiled-coil, rootletin"
                     /db_xref="GeneID:313663"
                     /db_xref="RGD:1305364"
     exon            1..189
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..6162
                     /gene="Crocc"
                     /codon_start=1
                     /product="rootletin"
                     /protein_id="NP_001402864.1"
                     /db_xref="GeneID:313663"
                     /db_xref="RGD:1305364"
                     /translation="MSLGLAESLQAQLALEIVIQTLESCVLEPDQEKSLSVQNPAQDF
                     QGASLPVCVREIITSNLSQPETPAPLQVPEMASLLSLQEENQLLQQELSRVEDLLAQS
                     RAERDELAIKYNAINERLEQAVRLETGELEAQEPRGLVRQSVELRRQLQEEQASYRRK
                     LQAYQEGQQRQAQLVQRLQAKILQYKKQCSEMEKQLLERSTELEQQRLRDTEHSQDLD
                     RALLRLEEEQQRSASLAQVNDMLREQLDQANLANQTLSEDICKVTSDWTRSCKELEQR
                     EATWRREEESFNAYFSSEHSRLLLLWRQVMGLRRMASEVKMGTERDLLQLGGELVRTS
                     RAVQEVGLGLSASLQRAESRAEAALEKQKLLQAQLEEQLRAKLLREKDLAQLQVQSDL
                     DKADLSARVTELALSVEHLQNQNTEKDQVNRTLSDKLEALESLRLQEQTTLDTEDGEG
                     LQQTLRDLAQAALSDTESGVQLSNSERTADTSDGSFRGLFGQRTPTPPRHSSPGRGRS
                     PRRGLSPACSDSSTLTLIHSALHKRQLQVQDMRGRYEASQDLLGSVRKQLSDSEGERR
                     GLEEQLQRLRDQTATSVQAQEDAQREAQRLRSANEILSREKGNLSHSLQVAQQQAEDL
                     RQELEKLQAAQEELRRQHTQLEDQQEDTVQEGARARRELERSHRQLEQLEVKRSGLTK
                     ELVEVREALSCAVLQRDVLQTEKAEVAEALTKAEAGRAQLELSVTKLRAEEASLRDSL
                     SKMSALNESLAQDKLELNRLIAQLEEEKAALLGRQQQAEHATSLAVEKQERLEQLRLE
                     QEVERQGLEGSLCVAEQAREALGQQILVLRSERSHLQEQVAQLSRQLNGRDQELDQAL
                     RESQRQVEALERAAREKEAMAKERAGLAVQLAAAEREGRTLSEETIRLRLEKEALESS
                     LFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTATEEKAALDKELMT
                     QKLVQAERETQASLREQRAAHEEDLQRLQREKEAAWRELQAERAQLQGQLQQEREELL
                     ARMEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLA
                     AISLEMERQKRDAQSRQEQDRNTVNALTSELRDLRAQLEEATAAHAQQVKELQEQTGN
                     LGRQREACMREAEELRTQLRLLEDTRDGLRRELLEAQRKVRDSQDSSEAHRQEASELR
                     RSLSEGTKEREALRRSNEELRTAVKKAESERISLKLANEDKEQKLALLEEARMSVAKE
                     AGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQSRLALGERTEK
                     ESRREVLGLRQKVLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGA
                     EKKLLDSARSLELRLEGVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLG
                     GLRSALRRGLGLGRVSSSPAREAPAGGSGDGLSSPSPLEYSPRSQPPSPGPVASPAPP
                     DLDPEAVRDALRDFLQELRSAQRERDELRVQTSTLSQQLAEMEAERDHAASRAKQLQK
                     AVAESEEAWRSADRRLSGAQAELALQEESVRRSRRECRATLDQMAVLERSLQATESEL
                     RASQEKVNKMKATEVKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGD
                     REAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGTLRSKVQSLT
                     DALAQSSASLTSSQDKNLYLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQ
                     VQTLRGELANLELQRGDAEGQLQQLQQVLRQRQEGEAVALRSVQKLQEERRLLQERLG
                     SLQRALAQLEAEKRELERSALQLDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRL
                     DRTLTGAELDLAEAQQQIQHLEAQVVEVLERNHSPVQVEADEQHLELQQEVERLRSAQ
                     VRTERTLEARERAHRQRVSGLEEQVSTLKAQLHQERHRSSASMSPPSGTPEK"
     exon            190..331
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            332..486
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            487..672
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            673..756
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            757..818
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            819..984
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1091
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1328
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1425
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            1426..1509
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            1510..1743
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            1744..1943
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            1944..2126
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            2127..2271
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            2272..2418
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            2419..2649
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            2650..2843
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            2844..2971
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            2972..3141
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            3142..3321
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            3322..3456
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            3457..3600
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            3601..3839
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            3840..3999
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            4000..4167
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            4168..4516
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            4517..4686
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            4687..4807
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            4808..4971
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            4972..5187
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            5188..5412
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            5413..5562
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            5563..5763
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            5764..5895
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            5896..6075
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
     exon            6076..6614
                     /gene="Crocc"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aatctgctgg gctgctcagc ctagcatcct ggcgttggtg tgttagtgcc ttggtgcgtg
       61 tcgctgaggt gaccttcgac cttcgtactg tgaggagggg ggctgtggag tacccacaga
      121 cccccctcca tgagcctggg gctggcagaa tccctgcagg cccagctggc actggagatt
      181 gtgatccaga cactggagag ttgtgtcctg gaaccagacc aagagaagag cctgagtgta
      241 cagaacccag cccaggattt ccagggagcc agcctacctg tctgtgttag ggagatcatc
      301 accagcaacc tctcccagcc tgagacccca gccccactcc aggtcccaga gatggcctca
      361 ctgctgtccc tgcaggagga aaaccagctg ctgcagcagg agctgtcccg ggtggaggac
      421 ctgctggccc agagccgtgc agagcgtgat gaacttgcca tcaagtacaa tgccatcaat
      481 gagaggctgg agcaggctgt gcggctggag actggggagc tggaggcaca ggagccccgg
      541 ggtctggtgc ggcagagcgt ggagctgagg aggcagctgc aggaggagca ggcctcctac
      601 cggcgcaagc tacaggccta ccaggagggc cagcagcggc aggcccagct agtgcagcgg
      661 ctgcaggcca agatcctgca gtacaagaag cagtgctcag agatggagaa gcagctgctg
      721 gaaaggtcca ccgagctgga gcagcagcga ctgagggaca cagagcacag ccaggacctg
      781 gacagagctc ttctgcgcct agaggaagag cagcagagaa gtgccagctt ggcccaggtg
      841 aacgacatgc tgagagagca gctagaccag gcaaacctgg ccaaccagac tctgagcgag
      901 gacatttgca aggtgaccag tgactggacc cgaagctgta aggagctgga acagagggag
      961 gcaacatgga ggcgtgagga ggagtccttc aacgcctact tcagcagcga gcacagccgc
     1021 ctgctgctcc tctggaggca ggtcatgggg ctccgaagga tggccagcga ggtgaagatg
     1081 ggcaccgaga gggacctact acagctagga ggagaactag tccggacatc ccgggctgtc
     1141 caggaggtgg gcctaggact gagtgccagc ctgcagcggg ctgagagcag ggctgaggcg
     1201 gctctggaga agcaaaagct gctgcaggcc caactggagg agcagctacg ggccaagctg
     1261 ctccgggaga aggacctggc ccagcttcag gtgcagagtg acctggacaa ggctgatctc
     1321 agtgccagag tgacagagct ggccttgtct gtggaacacc ttcagaacca gaacacagag
     1381 aaggaccagg tcaacaggac cctctctgac aagttggagg ccctggagtc tctgcggctc
     1441 caggagcaga caaccctgga cactgaggat ggagaggggc tgcagcagac cttgagagac
     1501 ctggcacagg ctgccctctc tgatactgag agtggtgtcc agctcagcaa ctcagagcgc
     1561 actgcggata cctcagacgg cagcttccgc ggcctctttg gccagcggac tccaactcca
     1621 ccgcggcact cctccccggg tcgaggtcgt tctccacgcc gaggtctgtc cccagcctgc
     1681 tctgactcct ccacactcac gctgatccac tctgccctgc acaagcgcca gctacaggtc
     1741 caggacatgc gtgggcgcta tgaagccagc caagatctgt tgggttccgt gcgcaagcaa
     1801 cttagtgaca gtgagggtga gcggcgtggc ctggaggagc agctacagcg cctccgggac
     1861 cagacagcaa cctcagtcca ggcccaagag gatgcgcagc gtgaggccca gcgcctacgc
     1921 agtgccaacg agatcctgag cagggagaag ggcaacctga gccacagcct gcaggtggcc
     1981 cagcagcaag ctgaggatct gcgccaggag ctggaaaagc tgcaggccgc ccaggaggag
     2041 ctgaggcggc agcacaccca gctggaggac cagcaggagg acacggtgca ggagggcgcc
     2101 cgggcccgcc gcgagctaga gcgcagccat cggcagctgg agcagctgga agtgaagcgc
     2161 tcggggctga ccaaggagct ggtggaggtg cgggaggcac tgagctgcgc tgtactgcag
     2221 agggatgtgc tgcagacaga gaaggcagag gtggctgagg cgctgaccaa ggctgaggca
     2281 ggccgtgcgc agctggagct ctctgtgacc aagctgaggg cagaggaggc ttccctgcga
     2341 gattccttgt ccaagatgag tgccctcaac gagagtctcg cccaggacaa gctggaatta
     2401 aaccgcctca tcgcccagct agaggaagaa aaggcggcgc tcctgggccg ccagcagcag
     2461 gcggagcacg ccacttcgct ggctgtggag aagcaggaac ggttggagca gctgagactg
     2521 gagcaggagg tggagaggca gggcctggag ggctccctgt gtgtggctga gcaggcccgg
     2581 gaggcgctgg ggcagcagat ccttgtattg cgcagcgaac gcagccatct gcaggagcag
     2641 gtggcccagc tctcccggca gctgaatgga cgggaccagg agttggatca ggccctgcgg
     2701 gagtcccagc ggcaggtgga ggccctggag cgcgctgccc gggagaagga ggcgatggcc
     2761 aaggaacggg ctggcctggc tgtgcagctg gcagcagccg agcgtgaggg ccggaccctg
     2821 tcagaggaga ccattcgcct gcgcttggag aaggaggccc tggagagcag cctgtttgac
     2881 gtgcagaggc agctggctca gctcgaggcc cgccgggagc agctagaagc ggacagtcaa
     2941 gccctgctgc tggccaagga aactctgact ggggagctgg caggcctgcg gcagcaggta
     3001 acagccactg aagagaaagc ggccttggac aaggagctga tgacccagaa gctagtgcaa
     3061 gcagagcggg agactcaggc ctctctgcgg gaacagcggg cagcccatga ggaggatctg
     3121 cagagactcc agcgggagaa ggaggctgca tggcgggagc ttcaggcaga gcgggcccag
     3181 ctgcagggcc agttacagca ggagcgagag gagctgctgg cccggatgga ggctgagaag
     3241 gaggagctga gtgaggagat cgccgcgctg cagcaggagc gggacgaggg cctgctcctg
     3301 gcggagagtg agaagcagca ggccttgtcc ttgaaggagt ctgagaagac ggcactgtca
     3361 gagaagttga tgggaacccg gcacagtctg gctgccatct ctctggagat ggaacggcag
     3421 aagcgagatg cccagagccg gcaggaacag gaccggaaca cagtgaacgc cctaacatct
     3481 gaacttcgag acctccgggc tcagctggaa gaagccacag cagcccatgc acagcaggtg
     3541 aaagaactcc aggagcagac ggggaacctg ggtcggcagc gggaggcctg catgagggag
     3601 gcagaagagc tgaggactca gctgcgcttg ttggaggata cccgtgatgg gctgcggcgg
     3661 gagctgctgg aggctcagcg caaggtccgg gacagccagg acagctccga ggcccatcgc
     3721 caggaggcta gtgagctgcg gcgcagtctg agtgagggca ccaaggagcg tgaggccctg
     3781 cggcgttcca acgaggagct gaggaccgct gtgaagaagg cagagagcga gcggatcagc
     3841 ctgaagcttg ccaatgagga caaggagcag aagctggccc tcctggaaga ggctcgaatg
     3901 tctgtcgcca aggaggctgg agagcttcgg gcctcactgc aggaagtgga gcgatcccgg
     3961 ctggaggctc gacgtgagct gcaggagctt aggcgacaga tgaagactct ggacagtgac
     4021 aatggccgac tgggccgtga gctggcagac ctgcagagcc gcttggccct gggcgagcgg
     4081 acagagaagg agagccggcg agaggtcctg ggcctgcggc agaaggtgct gaaaggcgag
     4141 agcagcctgg aggccttgaa gcaggagctc cagggttccc agaggaagct gcaggagcaa
     4201 gaggctgagt tccgtgcacg cgaacgaggc ctgttgggct ccctggagga ggcgcgtggt
     4261 gccgagaaga agcttctgga ctctgctcgc agcctggagc taagactgga gggtgtgcgg
     4321 gcagagacct cagagctggg gctgcggctg agtgcagctg agggccgggc ccagggcctg
     4381 gaggtcgagc ttgcccgcgt ggaggcgcag cgccgggtag ccgaggccca gctgggtggc
     4441 ctgcgctccg ccctgcgccg gggcctgggc ctgggccgag tgtccagctc cccggctcga
     4501 gaggcccctg caggaggaag tggggacgga ctcagcagcc ccagtccttt ggaatatagc
     4561 cctcggtccc agcccccgtc tccagggcct gttgcctccc cggcacctcc agacttggac
     4621 ccagaagctg tgcgtgacgc cctccgagat tttctgcaag agctgcggag tgcccagcgg
     4681 gagcgggatg aacttagagt ccagactagc accctgagtc aacagctggc tgagatggag
     4741 gccgagagag accatgcagc ctcaagggcc aagcagctgc agaaggcagt agctgagagc
     4801 gaggaagcct ggcgcagtgc agacaggcgg ctgagcgggg cccaggccga gctggcactg
     4861 caggaagaga gtgtgcgacg tagcaggcgg gagtgcaggg ccacgctgga ccagatggca
     4921 gtgctggaga ggagcctgca ggccaccgag agcgagctcc gggccagcca ggagaaggtc
     4981 aacaagatga aggccactga ggtgaagctg gagagcgaca agcggcgact gaaggaggtg
     5041 ctggatgcgt ctgagagccg ctccatcaaa ctggagctgc agcggcgcgc tctcgagggc
     5101 gagctgcagc gcagccgcct aggcctgggg gaccgtgagg cccacgctca ggccctccag
     5161 gatcgggtgg actccctgca gagacaggtg gcagacagtg aggtgaaggc agggacctta
     5221 cagctaacag tggagcggct cagtggggca ctggccaagg tggaggagag cgaggggacc
     5281 ctgcggagca aggtgcagag cctgacagat gccctggccc agagcagtgc cagtctcacc
     5341 agcagtcagg acaagaatct gtacctacag aaggccttga gtacctgcga acatgaccgc
     5401 caagtgctgc aggaacggct ggacgctgcc agacaggcac tgtctgaagc tcgaaggcaa
     5461 agcagctccc tgggtgagca ggtgcagact ctgcggggtg agctggccaa cctggagctg
     5521 cagcggggcg atgctgaagg ccagctgcag cagctgcagc aggtgctgcg gcagcggcag
     5581 gaaggggagg ccgtggcttt gcgctccgtc cagaagctac aggaggagcg gcgcctgttg
     5641 caggagcgcc tgggcagtct gcagcgagcc ctggcccagc tggaagctga gaaacgtgag
     5701 ctggagcggt cggcactgca gctggacaag gaccgtgtgg cactcaggaa gacactggac
     5761 aaggtggagc gggagaagct tcgaagccac gaggacacac tgcgcttgaa tgcagagagg
     5821 ggccgcctgg accgcacact cacaggagct gagctggacc tggctgaagc ccaacagcag
     5881 atccaacatt tagaggcaca ggtggtggaa gtcctggagc ggaaccacag tcctgtccag
     5941 gtggaggcag atgagcagca cctggagctg caacaggagg ttgagcgcct gcgcagtgcc
     6001 caggtacgga cagagcgcac actggaggca cgggagcggg cccaccgcca gcgcgtgtcg
     6061 gggctggagg agcaggtatc cacactgaag gcacagctgc atcaggagcg tcaccggagc
     6121 tcagcatcca tgtccccacc ctctggcacc ccagagaaat gagtcccttc cagcccatat
     6181 cctgagcagt ccctgggcag gagagaggcc ctctgtagca tagtctgccc agggcctggt
     6241 catcagagtg ctgggtgagg gagctggggt ggcagagatg atggctgtgg tgacacccac
     6301 agtggcttct cagagcgact gcagcacctg tactaccctg gcctctcaag aagagtctct
     6361 tgatggtcca aggctctcct gcttggcgga gccagccagg catcagggag ggagagcact
     6421 tgtttccgcc cgccagcagc agagcaaagg ttccccagac agggtacctg agccagagca
     6481 cccggcttct ccttagcatc ctcgtcagag tcggaagctc cctcgtgagc ttagagccct
     6541 tgtatttttg tatcttttta taatgttcac tgtggagaac atgtgctttt tgtaacatga
     6601 cctgttttct agaa
//
