LOCUS       NM_001106074            1668 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus cytokine receptor-like factor 1 (Crlf1), mRNA.
ACCESSION   NM_001106074 XM_001070792 XM_214312
VERSION     NM_001106074.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1668)
  AUTHORS   Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X,
            Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K,
            Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A and Mayr
            M.
  TITLE     Extracellular matrix secretion by cardiac fibroblasts: role of
            microRNA-29b and microRNA-30c
  JOURNAL   Circ Res 113 (10), 1138-1147 (2013)
   PUBMED   24006456
REFERENCE   2  (bases 1 to 1668)
  AUTHORS   Caruana G, Cullen-McEwen L, Nelson AL, Kostoulias X, Woods K,
            Gardiner B, Davis MJ, Taylor DF, Teasdale RD, Grimmond SM, Little
            MH and Bertram JF.
  TITLE     Spatial gene expression in the T-stage mouse metanephros
  JOURNAL   Gene Expr Patterns 6 (8), 807-825 (2006)
   PUBMED   16545622
REFERENCE   3  (bases 1 to 1668)
  AUTHORS   Heese K, Yamada T, Akatsu H, Yamamoto T, Kosaka K, Nagai Y and
            Sawada T.
  TITLE     Characterizing the new transcription regulator protein p60TRP
  JOURNAL   J Cell Biochem 91 (5), 1030-1042 (2004)
   PUBMED   15034937
REFERENCE   4  (bases 1 to 1668)
  AUTHORS   Forger NG, Prevette D, deLapeyriere O, de Bovis B, Wang S, Bartlett
            P and Oppenheim RW.
  TITLE     Cardiotrophin-like cytokine/cytokine-like factor 1 is an essential
            trophic factor for lumbar and facial motoneurons in vivo
  JOURNAL   J Neurosci 23 (26), 8854-8858 (2003)
   PUBMED   14523086
REFERENCE   5  (bases 1 to 1668)
  AUTHORS   Knappskog PM, Majewski J, Livneh A, Nilsen PT, Bringsli JS, Ott J
            and Boman H.
  TITLE     Cold-induced sweating syndrome is caused by mutations in the CRLF1
            gene
  JOURNAL   Am J Hum Genet 72 (2), 375-383 (2003)
   PUBMED   12509788
REFERENCE   6  (bases 1 to 1668)
  AUTHORS   Elson GC, Lelievre E, Guillet C, Chevalier S, Plun-Favreau H,
            Froger J, Suard I, de Coignac AB, Delneste Y, Bonnefoy JY, Gauchat
            JF and Gascan H.
  TITLE     CLF associates with CLC to form a functional heteromeric ligand for
            the CNTF receptor complex
  JOURNAL   Nat Neurosci 3 (9), 867-872 (2000)
   PUBMED   10966616
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474031.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_214312.3, XM_001070792.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132262, SAMD00132264
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1668
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..1668
                     /gene="Crlf1"
                     /note="cytokine receptor-like factor 1"
                     /db_xref="GeneID:290655"
                     /db_xref="RGD:1311371"
     exon            1..245
                     /gene="Crlf1"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..1399
                     /gene="Crlf1"
                     /codon_start=1
                     /product="cytokine receptor-like factor 1 precursor"
                     /protein_id="NP_001099544.1"
                     /db_xref="GeneID:290655"
                     /db_xref="RGD:1311371"
                     /translation="MPAGGPGPAAQSARRPPRRLSSLWSPLLLCVLGVPQGGSGAHTA
                     VISPQDPTLLIGSSLHATCSIHGDTPGATAEGLYWTLNGRRLPSELSRLLNTSTLALA
                     LANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTP
                     GAHGETFLHTNYSLKYKLRWYGQDNTCEEYHTVGPHSCHIPKDLALFTPYEIWVEATN
                     RLGSARSDVLTLDVLDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQ
                     IRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWS
                     HPTAASTPRSERPGPGGGVCEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYD
                     QWRAWMQKSHKTRNQDEGILPSGRRGAARGPAG"
     exon            246..527
                     /gene="Crlf1"
                     /inference="alignment:Splign:2.1.0"
     exon            528..657
                     /gene="Crlf1"
                     /inference="alignment:Splign:2.1.0"
     exon            658..827
                     /gene="Crlf1"
                     /inference="alignment:Splign:2.1.0"
     exon            828..985
                     /gene="Crlf1"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1154
                     /gene="Crlf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1155..1342
                     /gene="Crlf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1343..1385
                     /gene="Crlf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1668
                     /gene="Crlf1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccggccttc gctgtccgcg cccagtgacg tgcgtgcgga cccaaacccc aatctgcacc
       61 ccgcagagtc gcccccgccc cataccggcg ttgcagtcac cgcccgttgc gcgccacccc
      121 catgcccgcc ggtggcccgg gccccgccgc ccaatccgcg cggcggccgc cgcggcggct
      181 ctcctcgctg tggtcgcctc tgttgctctg tgttctcggg gtgcctcagg gcggatcggg
      241 agcccacaca gctgtgatca gtccccagga ccccactctt ctcatcggat cctcccttca
      301 tgctacgtgc tctatacatg gagacacacc gggggccact gctgagggcc tctactggac
      361 cctcaacggc cgccgcctgc cctcagagct gtcccgtctc ctcaacacct ccaccctggc
      421 cttggccctg gctaacctta atgggtccag gcagcagtca ggggacaatc tggtgtgtca
      481 cgcccgagat ggcagcattc tggctggttc ctgcctctat gttggtctgc ccccggagaa
      541 gccctttaac atcagctgct ggtcccggaa catgaaggac ctgacatgcc gttggacacc
      601 gggtgcacat ggggagacat tcctacacac caactactcc ctcaagtaca agctgaggtg
      661 gtatggtcag gacaacacat gtgaggaata tcacactgtg ggccctcact cgtgccatat
      721 ccccaaagac ctggccctct tcacgcccta tgagatctgg gtggaagcca ccaatcgcct
      781 gggttcagcg agatctgacg tgctcacact ggatgtcctg gacgtggtga ccacggaccc
      841 tccacccgac gtgcacgtga gccgcgttgg gggcctggag gaccagctga gtgtgcgctg
      901 ggtctcacca ccagctctca aggatttcct cttccaagcc aaataccaga ttcgctaccg
      961 cgtggaggac agcgtggact ggaaggtggt ggatgacgtc agcaaccaga cctcctgccg
     1021 tctcgcgggc ttgaagcccg gcaccgttta cttcgtccaa gttcgttgta acccattcgg
     1081 gatctatggg tcgaaaaagg cgggaatctg gagcgagtgg agccacccca ccgctgcctc
     1141 cacccctcga agtgagcgcc cgggcccggg cggcggggtg tgcgagccgc ggggcggcga
     1201 gcctagctcg ggcccggtgc ggcgcgagct caagcagttc ctcggctggc tcaagaagca
     1261 cgcgtactgc tcgaacctta gcttccgcct gtacgaccag tggcgtgctt ggatgcagaa
     1321 gtcacacaag acccgaaacc aggacgaggg gatcctgccc tcgggcagac ggggtgcggc
     1381 gagaggtcct gccggctaaa ctctgaggat aggccatcct cctgctggat gcagacctgg
     1441 aggctcacct gaactggaga ccatctgtac tgtcactttg gggcaatgaa gaaacaaacc
     1501 aggggctggg gcacaatgag ctcccacaac cacagctttg gccacatgat ggtcaacttt
     1561 ggatgtaccc caatatgggt agggttggag taatgacaag ggttatgcag gaccctccaa
     1621 gagtctcttt gaataaataa gaaaagagtt gttcaggtcc cgtggtgg
//
