LOCUS       NM_022501               1154 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cysteine-rich protein 2 (Crip2), mRNA.
ACCESSION   NM_022501
VERSION     NM_022501.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1154)
  AUTHORS   Didangelos,A., Yin,X., Mandal,K., Baumert,M., Jahangiri,M. and
            Mayr,M.
  TITLE     Proteomics characterization of extracellular space components in
            the human aorta
  JOURNAL   Mol Cell Proteomics 9 (9), 2048-2062 (2010)
   PUBMED   20551380
REFERENCE   2  (bases 1 to 1154)
  AUTHORS   Gao,X., Sun,J.Y., Cao,Z.Y., Lin,Y., Zha,D.J., Wang,F., Xue,T.,
            Qiao,L., Lu,L.J. and Qiu,J.H.
  TITLE     Polyclonal antibodies to LIM proteins CRP2 and CRIP2 reveal their
            subcellular localizations in olfactory precursor cells
  JOURNAL   Biochemistry (Mosc) 74 (3), 336-341 (2009)
   PUBMED   19364329
  REMARK    GeneRIF: Results demonstrated that in undifferentiated olfactory
            precursor cells Csrp2 was distributed both in the nucleus and the
            cytoplasm, whereas CRIP2 was predominantly localized in the
            cytoplasm.
REFERENCE   3  (bases 1 to 1154)
  AUTHORS   van Ham,M., Croes,H., Schepens,J., Fransen,J., Wieringa,B. and
            Hendriks,W.
  TITLE     Cloning and characterization of mCRIP2, a mouse LIM-only protein
            that interacts with PDZ domain IV of PTP-BL
  JOURNAL   Genes Cells 8 (7), 631-644 (2003)
   PUBMED   12839623
REFERENCE   4  (bases 1 to 1154)
  AUTHORS   Tulin,E.E., Onoda,N., Hasegawa,M., Nosaka,T., Nomura,H. and
            Kitamura,T.
  TITLE     Genetic approach and phenotype-based complementation screening for
            identification of stroma cell-derived proteins involved in cell
            proliferation
  JOURNAL   Exp Cell Res 272 (1), 23-31 (2002)
   PUBMED   11740862
REFERENCE   5  (bases 1 to 1154)
  AUTHORS   Okano,I., Yamamoto,T., Kaji,A., Kimura,T., Mizuno,K. and
            Nakamura,T.
  TITLE     Cloning of CRP2, a novel member of the cysteine-rich protein family
            with two repeats of an unusual LIM/double zinc-finger motif
  JOURNAL   FEBS Lett 333 (1-2), 51-55 (1993)
   PUBMED   8224170
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from D17512.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D17512.1, FQ233584.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1154
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..1154
                     /gene="Crip2"
                     /gene_synonym="CRP2"
                     /note="cysteine-rich protein 2"
                     /db_xref="GeneID:338401"
                     /db_xref="RGD:1302959"
     exon            1..99
                     /gene="Crip2"
                     /gene_synonym="CRP2"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..683
                     /gene="Crip2"
                     /gene_synonym="CRP2"
                     /note="LIM/double zinc-finger protein; CRP-2"
                     /codon_start=1
                     /product="cysteine-rich protein 2"
                     /protein_id="NP_071946.1"
                     /db_xref="GeneID:338401"
                     /db_xref="RGD:1302959"
                     /translation="MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCNKTLTPGGH
                     AEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPPTEAPQVTGPIEVPVVRTEERK
                     TSGPPKGPSKASSVTTFTGEPNMCPRCNKRVYFAEKVTSLGKDWHRPCLRCERCSKTL
                     TPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDKDPEGTVQP"
     exon            100..252
                     /gene="Crip2"
                     /gene_synonym="CRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            253..393
                     /gene="Crip2"
                     /gene_synonym="CRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            394..462
                     /gene="Crip2"
                     /gene_synonym="CRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            463..557
                     /gene="Crip2"
                     /gene_synonym="CRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            558..615
                     /gene="Crip2"
                     /gene_synonym="CRP2"
                     /inference="alignment:Splign:2.1.0"
     exon            616..1154
                     /gene="Crip2"
                     /gene_synonym="CRP2"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1154
                     /gene="Crip2"
                     /gene_synonym="CRP2"
ORIGIN      
        1 cggcggcgca gagaggagcg cgggtggagg gcgcggaccg accgagcgca ccgaccatgg
       61 cctccaagtg tcccaagtgt gacaagaccg tgtacttcgc cgagaaggtg agctccctgg
      121 gcaaggactg gcacaagttc tgcctcaagt gtgagcgctg caacaagaca ctgacgcctg
      181 gcggccatgc tgagcatgat gggaaaccct tctgccacaa gccctgttat gccacactgt
      241 ttggacccaa aggcgtgaat atcgggggcg ctggttccta catctacgag aagcctccga
      301 cggaggcccc tcaggtcact ggccccatcg aggtccctgt ggtacgaact gaagagcgga
      361 agaccagcgg gccgcccaag ggtcccagca aagcctctag tgtcaccacg ttcactgggg
      421 agcccaacat gtgccctcga tgcaacaaga gagtgtactt cgctgagaag gtgacctccc
      481 tgggcaagga ctggcaccga ccctgcctgc gctgtgagcg ctgctccaag acactgaccc
      541 caggcgggca tgctgagcat gatggccaac cctactgcca caagccctgc tatggaatac
      601 tctttggacc caaaggagtg aatactggtg ctgtgggcag ctacatctac gacaaggacc
      661 cggaaggcac agttcagcct tagatctgca gatgctgccc ctcgcggtcc cctatttgac
      721 cctgagggag agtgatctgc tgcctagtcc tgcctcagtg tgtctcgcct gcaattccag
      781 cacctaagtg atggaggaga aagcccagct agtcctagaa tttcagctcc cttggtcacc
      841 ttggcatgtc ctatgttgcc cgtggtttac tttctgtctg tgtgtctcca tagcaccatg
      901 ggtcctgtgt ccccatgtcc ctgataactc tccaaggtgg ctgtcctatg atatcccttt
      961 gcccacactc gcccgccagt attatttatg ctctgcttgc cggtgatggg catgagctag
     1021 ctcacagcat tcccggggtg acggcacccc agcaaggagc cctttgctgg ttcccacact
     1081 actccctact taccctcaca tggttcacag ctatggagat ttgctgtcaa taaatagttt
     1141 ggtttaaaga ttgc
//
