LOCUS       NM_001169103            4076 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus cysteine rich transmembrane BMP regulator 1
            (Crim1), mRNA.
ACCESSION   NM_001169103 XM_001064272 XM_233798
VERSION     NM_001169103.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4076)
  AUTHORS   Ahmed,S.M., Theriault,B.L., Uppalapati,M., Chiu,C.W., Gallie,B.L.,
            Sidhu,S.S. and Angers,S.
  TITLE     KIF14 negatively regulates Rap1a-Radil signaling during breast
            cancer progression
  JOURNAL   J Cell Biol 199 (6), 951-967 (2012)
   PUBMED   23209302
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On or before Dec 16, 2009 this sequence version replaced
            XM_001064272.1, XM_233798.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.24439.1,
                                           SRR26643293.33829.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840106,
                                           SAMN12840107 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-852               JAXUCZ010000006.1  22621565-22622416   c
            853-1026            JAXUCZ010000006.1  22582200-22582373   c
            1027-1269           JAXUCZ010000006.1  22539329-22539571   c
            1270-1390           JAXUCZ010000006.1  22538169-22538289   c
            1391-1512           JAXUCZ010000006.1  22516389-22516510   c
            1513-1695           JAXUCZ010000006.1  22506429-22506611   c
            1696-1893           JAXUCZ010000006.1  22504019-22504216   c
            1894-2022           JAXUCZ010000006.1  22484602-22484730   c
            2023-2179           JAXUCZ010000006.1  22478688-22478844   c
            2180-2301           JAXUCZ010000006.1  22477206-22477327   c
            2302-2511           JAXUCZ010000006.1  22475277-22475486   c
            2512-2727           JAXUCZ010000006.1  22471705-22471920   c
            2728-2949           JAXUCZ010000006.1  22470432-22470653   c
            2950-3144           JAXUCZ010000006.1  22456257-22456451   c
            3145-3267           JAXUCZ010000006.1  22454162-22454284   c
            3268-3458           JAXUCZ010000006.1  22451504-22451694   c
            3459-4076           JAXUCZ010000006.1  22449948-22450565   c
FEATURES             Location/Qualifiers
     source          1..4076
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q12"
     gene            1..4076
                     /gene="Crim1"
                     /note="cysteine rich transmembrane BMP regulator 1"
                     /db_xref="GeneID:298744"
                     /db_xref="RGD:1308710"
     exon            1..852
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     CDS             522..3635
                     /gene="Crim1"
                     /note="cysteine-rich motor neuron 1; cysteine rich
                     transmembrane BMP regulator 1 (chordin like)"
                     /codon_start=1
                     /product="cysteine-rich motor neuron 1 protein precursor"
                     /protein_id="NP_001162574.1"
                     /db_xref="GeneID:298744"
                     /db_xref="RGD:1308710"
                     /translation="MYLVAGGRGLAGCGHLSVSLLGLLLLLARSGTRALVCLPCDESK
                     CEEPRSCPGSIVQGVCGCCYMCARQRNESCGGAYGLHGACDRGLRCVIRPPLNGDSIT
                     EYEVGVCEDEDWDDDQLLGFEPCNENLISGCNIINGRCECSTIRTCNNPFEFPRKDMC
                     LSALKRIEEEKPDCTKARCEVQFSPRCPEDSILIEGYAPPGECCPLPSRCVCDPAGCL
                     RKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPPVQQAVCPLDSYETQ
                     VRLTADGCCTLPARCECLSGLCAFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNETKP
                     ACVFNSVEYYDGDMFRMDNCRFCRCQGGVSICFTAQCGELNCERYYVPEGECCPVCED
                     PIYPFNNPAGCYANGQIRAHGDRWREDDCTFCQCINGEPHCVATACGQSCMHPVKVPG
                     ECCPVCEEPTYITIDPPACGELSNCTLKEKDCVYGFKLDHNGCRTCQCKNREERCLAL
                     KRACTLDCPFGFLTDVHNCELCQCRPRPKKCRPTICDKFCPLGFLRNKHGCDICRCKK
                     CPELPCSKVCPLGFQEDSHGCLICKCREVPTSAGPPVLSGTCLSMDGHHHKNEESWHD
                     GCRECYCHNGKEMCALITCPVPACGNPTIRPGQCCPSCADDFVVQKPELSTPSICHAP
                     GGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTEDPLQ
                     PSTSHNESVPSYCRNDEGDIFLAAESWKPDVCTSCVCMDSSISCYSESCPSVACERPV
                     LRKGQCCPYCLEDTIPKKVVCHFSGKTYADEERWDIDSCTHCYCLQGQTLCSTVSCPP
                     LPCAEPIKVEGSCCPMCPEMYVPEPTNVPIEKKNHRGEIDLEVPMWPTPSENDIIHLP
                     RDMGHLQVDYRDNNRLHPSEDSSLDSIVPVVVPIIICLSIIIAFLLINQKKQWIPLLC
                     WYRTPTKPSSLNNQLVSVDCKKGTRVQVDGSQRMLRIAEPDARFSGFYSMQKQNHLQA
                     DNFYQTV"
     exon            853..1026
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1269
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1390
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1391..1512
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1695
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1696..1893
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            1894..2022
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            2023..2179
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            2180..2301
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            2302..2511
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            2512..2727
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            2728..2949
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            2950..3144
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            3145..3267
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            3268..3458
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
     exon            3459..4076
                     /gene="Crim1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggagagagc cgagccgggc gcaaggaacg gacgccacgg accttctgct gagccaccgc
       61 gcccactcgg cggctcggga ggcggggacc ggcccggagg ctgcgctgcc gtcgtctttc
      121 cccggcgatc aggagcagcg cggaggacca gaaggagcca ccagccctgc ttcggagcgg
      181 tgcgcagcca ccgccgccgc cagaagtttg ggttgaaccg gagctgccgc gaggaaactt
      241 tttttcctct ttttcccctc ccgcccggga ggaaaaggag gaggagggga agccacccgc
      301 cactgctgcc gctggcgcca acgctcgtgg gctccgggtc ggcgcggccc gcaggggcgg
      361 cgggggcctc gccccgagag gggaggagcg ccccgggggc ccctagtggg gcacgaggac
      421 cgcgggctgc gggtgcggcg gcggcgcgtg tgccccgcgc aggggagggc gcccgccccg
      481 ctcccggccc ggctgcgagg aggaggcggc ggcacaggag gatgtacttg gtggcggggg
      541 gcagggggct ggccggctgc gggcacctct cggtctcgct gctggggctg ctgctgctgc
      601 tggcgcgctc aggcacccgg gcgctggtct gcctgccctg tgacgagtcc aagtgcgagg
      661 agcctcggag ctgcccggga agcatcgtgc agggcgtctg cggctgctgc tacatgtgcg
      721 cccgccagag gaacgagagc tgcggtggag cctatgggct ccatggagcc tgcgaccggg
      781 ggctgcgctg tgtcatccgc cccccgctca atggcgactc catcaccgag tatgaagtgg
      841 gcgtctgcga agacgaggac tgggacgacg accagctgct cggttttgag ccctgcaatg
      901 agaacctcat ctcgggctgc aatatcatca acgggagatg cgaatgcagt accatccgaa
      961 cctgcaacaa cccctttgag ttcccaagga aggacatgtg cctttcggcc ttaaagagga
     1021 tcgaagaaga gaagccagat tgcaccaagg cccgctgtga agtgcagttc tctccacgtt
     1081 gccctgaaga ttccattctg attgagggct atgctccccc cggggagtgt tgtcctttac
     1141 ccagccgctg cgtgtgtgac cctgcgggct gtctgcgcaa agtctgccag ccgggatacc
     1201 tgaacattct agtgtccaaa gcctcaggga agccgggaga gtgctgtgac ctctatgagt
     1261 gtaaaccagt tttcagcgtg gactgcagca ccgtggagtg cccccctgtc cagcaggccg
     1321 tgtgccccct ggacagctac gaaacgcaag tgcggctcac agcggatggc tgctgtaccc
     1381 tgccagcaag atgcgagtgt ctctctggct tatgtgcttt tcccgtttgt gaggtgggat
     1441 ctactccccg aatagtctct cgtggagatg ggacacctgg aaagtgctgt gatgtctttg
     1501 aatgtgttaa tgaaacaaag ccagcctgcg tgttcaacag tgtggagtat tacgatggag
     1561 acatgtttcg aatggacaac tgtcggttct gtcggtgcca agggggcgtc tccatctgct
     1621 tcaccgccca gtgtggggaa ctgaactgcg aaagatacta tgtgcctgag ggggagtgtt
     1681 gccccgtgtg tgaagatccc atctatcctt tcaacaaccc cgccggctgc tacgccaacg
     1741 gccagatccg cgcccacggg gaccggtggc gggaagacga ctgcaccttc tgccagtgta
     1801 tcaatggaga accccactgc gtggccaccg cctgcgggca gagctgcatg caccccgtga
     1861 aagtgcctgg ggagtgttgc cccgtgtgtg aagaaccaac ctacatcaca attgatccac
     1921 ctgcgtgcgg ggagttgtca aactgtactc tgaaagagaa ggactgcgtt tacggcttca
     1981 aactggatca caatggctgt cgaacctgtc agtgcaaaaa cagggaggaa cgatgcttag
     2041 cccttaaaag ggcctgcact ttggactgtc ccttcggctt cctcaccgat gtccacaact
     2101 gtgagctctg tcagtgccgc ccacggccca agaaatgcag accaacaata tgcgacaagt
     2161 tttgtcctct tggattcctg aggaacaagc acggctgtga catctgtcgc tgtaagaagt
     2221 gtccagagct tccatgcagc aaggtctgcc ccttgggctt ccaggaggac agtcacggct
     2281 gtctcatctg caagtgcaga gaggtcccta cttcagccgg gccacctgtc ctgtcaggca
     2341 catgtctgtc catggatggt catcaccata aaaacgagga gagctggcat gatggctgcc
     2401 gggaatgcta ctgtcacaat gggaaggaaa tgtgtgccct catcacctgc ccagtgcctg
     2461 cctgcggcaa ccccaccatc cggcccggac agtgctgccc atcctgcgca gatgacttcg
     2521 tggtgcagaa gcccgagctc agcacgcctt ccatttgcca cgcccctgga ggagagtact
     2581 ttgtggaagg ggaaacgtgg aacattgact cctgtacgca gtgcacctgt cacagtggcc
     2641 gagtgctgtg tgagacggag gtgtgcccac cactgctctg ccagaacccc tcacgcaccc
     2701 aggactcctg ctgcccacag tgtacagagg accctcttca gccttccaca tcccataatg
     2761 agagcgtgcc tagctactgc aggaatgatg aaggggacat cttcctggcg gccgagtcct
     2821 ggaagcctga cgtctgcacc agctgcgtgt gcatggatag ctccattagc tgctactccg
     2881 agtcttgccc ttcggtggcc tgcgaacggc ccgttttgag gaaaggccag tgttgcccct
     2941 actgtctaga agacacgatt ccaaagaaag tggtgtgtca cttcagtggg aagacctacg
     3001 ctgacgagga gcggtgggac atcgacagct gcacacattg ctactgcctg caaggccaga
     3061 ccctctgctc gactgtcagc tgcccaccat taccctgtgc cgagcccatc aaggtggaag
     3121 ggagttgctg cccgatgtgc ccagaaatgt atgtgccaga gccaaccaat gtgcccattg
     3181 agaagaagaa tcatcgcggc gagattgacc tggaggttcc catgtggccc accccaagtg
     3241 aaaatgacat catccacctc cctagagata tgggtcacct ccaggtagat tacagagaca
     3301 ataacaggct gcatccaagt gaagactcat cattggactc cattgtcccc gttgtggttc
     3361 ccataatcat atgcctgtcc atcataatag cattcctgct catcaaccag aagaaacagt
     3421 ggataccgct gctgtgctgg taccggacac caaccaagcc ttcttccttg aataatcagc
     3481 tggtatcggt ggactgcaag aaaggcactc gggtccaggt ggacggttcc cagagaatgc
     3541 taagaatcgc tgaaccagat gcacgattca gtggcttcta cagcatgcag aaacagaacc
     3601 atctacaggc agacaatttc taccaaacgg tgtgaacgca ggcagcagtg cggatgaggt
     3661 ttcgaaagac ggagaacaac gacaaaaaaa caaacaaaca aacaaacaaa caaaaaaaca
     3721 aaaaaatatc tgctctttaa agtaaactag gatttgcgca cttgcttagt gtattgtatt
     3781 ggattgtgac ttggggtcca gcactaaggg ctggactggg atgggctctg tctacagcac
     3841 tgtgcagaac aagcattccc acttggcctc aagataactg accacatgtt ttcatagaac
     3901 caaagtttta aaacttgcta aagtatattt gcttgtaaga tagctgtaaa gacattcggg
     3961 ggtggggaca gagagtttgg tgggggaaat gggtcgggag ggtagtgttg ggaagaaaaa
     4021 caatcggtca gcttggcttg gggagaaagc cagtaaaaat aaaggcaatt cgtggc
//
