LOCUS       NM_001037208            1368 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cysteine-rich with EGF-like domains 2 (Creld2),
            mRNA.
ACCESSION   NM_001037208 XM_343308
VERSION     NM_001037208.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Oh-hashi,K., Kunieda,R., Hirata,Y. and Kiuchi,K.
  TITLE     Biosynthesis and secretion of mouse cysteine-rich with EGF-like
            domains 2
  JOURNAL   FEBS Lett 585 (15), 2481-2487 (2011)
   PUBMED   21729698
REFERENCE   2  (bases 1 to 1368)
  AUTHORS   Oh-hashi,K., Koga,H., Ikeda,S., Shimada,K., Hirata,Y. and Kiuchi,K.
  TITLE     CRELD2 is a novel endoplasmic reticulum stress-inducible gene
  JOURNAL   Biochem Biophys Res Commun 387 (3), 504-510 (2009)
   PUBMED   19615339
REFERENCE   3  (bases 1 to 1368)
  AUTHORS   Ortiz,J.A., Castillo,M., del Toro,E.D., Mulet,J., Gerber,S.,
            Valor,L.M., Sala,S., Sala,F., Gutierrez,L.M. and Criado,M.
  TITLE     The cysteine-rich with EGF-like domains 2 (CRELD2) protein
            interacts with the large cytoplasmic domain of human neuronal
            nicotinic acetylcholine receptor alpha4 and beta2 subunits
  JOURNAL   J Neurochem 95 (6), 1585-1596 (2005)
   PUBMED   16238698
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC098722.1.
            
            On Nov 18, 2005 this sequence version replaced XM_343308.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098722.1, SRR8487226.218036.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1368
                     /gene="Creld2"
                     /gene_synonym="RGD1310614"
                     /note="cysteine-rich with EGF-like domains 2"
                     /db_xref="GeneID:362978"
                     /db_xref="RGD:1310614"
     exon            1..167
                     /gene="Creld2"
                     /gene_synonym="RGD1310614"
                     /inference="alignment:Splign:2.1.0"
     CDS             48..1097
                     /gene="Creld2"
                     /gene_synonym="RGD1310614"
                     /EC_number="5.3.4.1"
                     /note="cysteine-rich with EGF-like domain protein 2;
                     protein disulfide isomerase Creld2"
                     /codon_start=1
                     /product="protein disulfide isomerase Creld2 precursor"
                     /protein_id="NP_001032285.1"
                     /db_xref="GeneID:362978"
                     /db_xref="RGD:1310614"
                     /translation="MHLLLAAGFGLLLLLLPPPAASKKPTQCQRCRTLVDKFNQGMAN
                     TARKNFGGGNTAWEEKTLSKYEFSEIRLLEIMEGLCDSSDFECNQLLEQQEEQLEAWW
                     QSLKKDYPNLFEWFCVRTLKACCLPGTYGPDCKECQGGSERPCSGNGYCSGDGSRQGD
                     GSCQCHAGYKGPLCIDCMDGYFSLQRNETHSICLACDESCKTCSGPSNKDCVQCEVGW
                     ARVEDACVDVDECAAETPPCSEAQYCENVNGSYICEECDSTCVGCTGKGPANCKECIA
                     GYTKQSGQCADIDECSLEEKACKRRNENCYNVPGSFVCVCPDGFEETEDACVQTAQSE
                     VTEENPTQPLSHEDL"
     exon            168..250
                     /gene="Creld2"
                     /gene_synonym="RGD1310614"
                     /inference="alignment:Splign:2.1.0"
     exon            251..361
                     /gene="Creld2"
                     /gene_synonym="RGD1310614"
                     /inference="alignment:Splign:2.1.0"
     exon            362..453
                     /gene="Creld2"
                     /gene_synonym="RGD1310614"
                     /inference="alignment:Splign:2.1.0"
     exon            454..630
                     /gene="Creld2"
                     /gene_synonym="RGD1310614"
                     /inference="alignment:Splign:2.1.0"
     exon            631..726
                     /gene="Creld2"
                     /gene_synonym="RGD1310614"
                     /inference="alignment:Splign:2.1.0"
     exon            727..810
                     /gene="Creld2"
                     /gene_synonym="RGD1310614"
                     /inference="alignment:Splign:2.1.0"
     exon            811..906
                     /gene="Creld2"
                     /gene_synonym="RGD1310614"
                     /inference="alignment:Splign:2.1.0"
     exon            907..1047
                     /gene="Creld2"
                     /gene_synonym="RGD1310614"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1344
                     /gene="Creld2"
                     /gene_synonym="RGD1310614"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagactccgc cgcagttctc ggtgggtcgc cgggctgccc tcccgccatg cacctgctgc
       61 ttgcagccgg gttcgggctg ctactgctgc tgctgccgcc acccgcggcc tccaagaagc
      121 cgacacagtg ccagaggtgc cggacgctgg tggacaagtt caaccagggg atggccaaca
      181 cggccaggaa gaatttcgga ggcggcaaca cggcgtggga agagaagact ctgtcgaagt
      241 atgaattcag tgagatccgg cttctggaga tcatggaggg tctgtgtgac agcagtgact
      301 ttgagtgcaa ccaactcttg gagcagcagg aagagcagct cgaggcctgg tggcagtccc
      361 tgaagaagga ttaccccaac ttatttgagt ggttctgtgt acgcacactg aaagcatgct
      421 gtcttccagg cacctacggg ccagactgta aagaatgcca gggtgggtcc gagaggcctt
      481 gtagcggcaa cggctactgc agcggcgatg gcagcaggca gggcgacggg tcctgccagt
      541 gtcacgcggg ctacaaggga ccactgtgta ttgactgcat ggatggctac ttcagtttgc
      601 agaggaacga gacccacagc atctgcttgg cctgtgatga gtcttgcaag acatgctcag
      661 gtccaagcaa caaagactgt gtccagtgtg aagtgggctg ggcacgagtg gaagacgcct
      721 gcgtggatgt agatgagtgt gcggcagaga cacctccctg cagtgaggca cagtactgtg
      781 agaatgtcaa cggatcgtac atctgtgaag aatgtgattc tacctgtgtg ggctgtacag
      841 gaaaaggccc agccaattgt aaagaatgca tcgctggcta caccaagcag agtggacagt
      901 gtgcagacat agatgaatgc tcactagaag aaaaagcctg taagagaaga aacgaaaact
      961 gctacaatgt tccagggagc tttgtgtgcg tgtgtccgga tggctttgag gagacagaag
     1021 acgcttgtgt gcagacagca caaagcgaag tcacagagga aaaccccaca cagccactct
     1081 cccatgagga tttgtgatag acatctggat tcagaagcca gactcaccct ttaagttatt
     1141 gagaggatat atatagaaaa tgtggcccat ggacatcaac cccatttctc caggaagacc
     1201 tcagagggag aagctgccta ctctgaaaaa gctgatactc acttggccct ttaaaaagct
     1261 gcatttcttg gtggttcata agcagatttg tatattttga tactgttctt tataataaaa
     1321 ttgatcattg aaggtcacca ggaaaaaaaa aaaaaaaaaa aaaaaaaa
//
