LOCUS       NM_001024783            1900 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cysteine-rich with EGF-like domains 1 (Creld1),
            mRNA.
ACCESSION   NM_001024783 XM_232270
VERSION     NM_001024783.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1900)
  AUTHORS   Robinson,S.W., Morris,C.D., Goldmuntz,E., Reller,M.D., Jones,M.A.,
            Steiner,R.D. and Maslen,C.L.
  TITLE     Missense mutations in CRELD1 are associated with cardiac
            atrioventricular septal defects
  JOURNAL   Am J Hum Genet 72 (4), 1047-1052 (2003)
   PUBMED   12632326
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097951.1.
            
            On Jun 10, 2005 this sequence version replaced XM_232270.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097951.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1900
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1900
                     /gene="Creld1"
                     /note="cysteine-rich with EGF-like domains 1"
                     /db_xref="GeneID:312638"
                     /db_xref="RGD:1309412"
     exon            1..112
                     /gene="Creld1"
                     /inference="alignment:Splign:2.1.0"
     exon            113..348
                     /gene="Creld1"
                     /inference="alignment:Splign:2.1.0"
     CDS             175..1437
                     /gene="Creld1"
                     /EC_number="5.3.4.1"
                     /note="cysteine-rich with EGF-like domain protein 1;
                     protein disulfide isomerase Creld1"
                     /codon_start=1
                     /product="protein disulfide isomerase Creld1 precursor"
                     /protein_id="NP_001019954.1"
                     /db_xref="GeneID:312638"
                     /db_xref="RGD:1309412"
                     /translation="MAPQPLRGLVPFLLWCLSLFLSLPGPVWLQPSPPPHSAPRAEPH
                     PCHTCRALVDSFNKGLERTIRDNFGGGNTAWEEEKLSKYKDSETRLVEVLEGVCSKSD
                     FECHRLLELSEELVEAWWFHRQQEAPDLFQWLCSDSLKLCCPSGTFGPSCLPCPGGTE
                     RPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNSSHLVCSACFGPC
                     ARCTGPEESHCLQCRKGWALHHLKCVDIDECGTEQATCGAAQFCVNTEGSYECRDCAK
                     ACLGCMGAGPGRCKKCSRGYQQVGSKCLDVDECETVVCPGENEQCENTEGSYRCVCAE
                     GFRQEDGICVKEQIPESAGFFAEMTEDEMVVLQQMFFGVIICALATLAAKGDLVFTAI
                     FIGAVAAMTGYWLSERSDRVLEGFIKGR"
     exon            349..431
                     /gene="Creld1"
                     /inference="alignment:Splign:2.1.0"
     exon            432..542
                     /gene="Creld1"
                     /inference="alignment:Splign:2.1.0"
     exon            543..634
                     /gene="Creld1"
                     /inference="alignment:Splign:2.1.0"
     exon            635..811
                     /gene="Creld1"
                     /inference="alignment:Splign:2.1.0"
     exon            812..907
                     /gene="Creld1"
                     /inference="alignment:Splign:2.1.0"
     exon            908..991
                     /gene="Creld1"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1087
                     /gene="Creld1"
                     /inference="alignment:Splign:2.1.0"
     exon            1088..1222
                     /gene="Creld1"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..1879
                     /gene="Creld1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgggaatcta accctctctc tctaattctg gcccctaata atccactgag accctaaaac
       61 aatgggctga cgcctattct tttgccagcg atcccggcca cctcccccta cggctggctt
      121 ttccagtgaa ccctccccct gccctctatc tgcacgttcc cagcctggga aaagatggct
      181 ccacagcccc taaggggcct ggtcccattt ctgctctggt gcttgagcct gtttcttagc
      241 ctcccaggac ctgtctggct ccaaccctct cctcctcccc attctgctcc ccgagctgag
      301 ccccatccat gtcatacctg ccgggcactg gtggacagct tcaacaaggg cctggagaga
      361 actatccggg acaactttgg tggtggaaac actgcttggg aggaagagaa gttgtccaaa
      421 tacaaagaca gtgagacccg cctggtggag gtgctggagg gtgtgtgcag caagtcagac
      481 ttcgagtgcc accgcctgct agagctcagc gaggagctgg tggaagcctg gtggttccac
      541 aggcagcaag aagcccctga cctcttccag tggctctgtt cagattccct gaagctctgc
      601 tgcccctctg ggactttcgg tccctcctgc ctgccatgtc ctgggggcac agagaggccc
      661 tgcggtggct acgggcagtg tgaaggggaa gggactcgag ggggcagcgg gcactgtgac
      721 tgccaagccg gctatggggg cgaggcctgt ggccagtgtg gccttggcta ctttgaggca
      781 gagcgcaaca gcagccatct ggtatgttcg gcgtgctttg gtccctgtgc ccgctgcaca
      841 ggacccgagg aatcccactg tctgcagtgc aggaaaggct gggccctgca tcacctcaag
      901 tgtgtagaca tcgatgagtg tggcacagag caagctacct gtggagccgc ccagttctgt
      961 gtgaacacgg aagggtccta tgagtgccga gattgtgcaa aggcctgcct gggctgtatg
     1021 ggagcagggc cagggcgctg caaaaaatgc agccgtggct accagcaggt gggctccaag
     1081 tgcctagatg tggatgagtg tgagacagtg gtgtgtccag gagagaacga gcagtgtgaa
     1141 aacacggaag gtagctaccg ctgtgtctgt gctgaaggct tcagacagga ggacggcatc
     1201 tgtgtgaagg agcagatccc agagtcggcg ggcttcttcg cggagatgac agaggacgaa
     1261 atggtggtcc tgcagcagat gttctttggt gtgatcatct gtgcactggc cacacttgct
     1321 gctaaggggg acttggtgtt caccgccatc ttcattggag ctgtggcagc tatgactggg
     1381 tactggttgt cagagcgcag tgaccgtgtg ctggagggct tcatcaaggg tagataatcc
     1441 ctgccaccac ttacaggatt tcctcccacc caggctgccc ctagaggtta tttctctctc
     1501 ccgctggaca cctgggacag cattgtttct ctttgagact ggggtaaata cccttttacc
     1561 tgccttactg agcagcccag gaccccagtg gccctggggg atgaaaaaga ggtcctgaag
     1621 ctgctgtctt gagatctttg cctagaggac tggcgggcct cacagtgtgt gaattccaag
     1681 acagtttctc cccagggagg ctgcaggtgg gcttcagccc ctgctctgga tgagaggcgt
     1741 cccctcaggg gtggggcccc cataggcctc ctgccaggtg catgctgcca gctcctgttg
     1801 tgtgttcacc gcccacaccc cagccattga cttatttatt catctcagga aataaaggac
     1861 ggtcttggaa actggaaaaa aaaaaaaaaa aaaaaaaaaa
//
