LOCUS       XM_039086668            7898 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus CREB binding protein (Crebbp),
            transcript variant X2, mRNA.
ACCESSION   XM_039086668
VERSION     XM_039086668.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051345.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039086668.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7898
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..7898
                     /gene="Crebbp"
                     /gene_synonym="CBP; RSTS; RTS"
                     /note="CREB binding protein; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 9 ESTs, 4 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     19 samples with support for all annotated introns"
                     /db_xref="GeneID:54244"
                     /db_xref="RGD:2401"
     CDS             426..7775
                     /gene="Crebbp"
                     /gene_synonym="CBP; RSTS; RTS"
                     /codon_start=1
                     /product="histone lysine acetyltransferase CREBBP isoform
                     X2"
                     /protein_id="XP_038942596.1"
                     /db_xref="GeneID:54244"
                     /db_xref="RGD:2401"
                     /translation="MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDEL
                     IPNGELSLLNSGNLVPDAASKHKQLSELLRGGSGSSITPGIGNVSASSPVQQGLGGQA
                     QGQPNSTSMASLGAMGKSPLNPGDSSTPSLPKQAASTSGPTPPASQALNPQAQKQVGL
                     VTSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRG
                     RGAGMPYPAPAMQGATSSVLAETLTQVSPQMAGHAGLNTAQAGGMTKMGMTGNTSPFG
                     QPFSQTGGQPMGATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIV
                     PAQGIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLN
                     HMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPAS
                     GIQNTIGSVGAGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQP
                     AQPPAHQQMRTLNALGNNPMSIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSN
                     SGSIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRR
                     MENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQP
                     ALPAPGAQPPVIPPTQSVRPPNGPLSLPVNRVQVSQGMNSFNPMSLGNVQLPQAPMGP
                     RAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHANNIMAQAPTQNQFLPQNQF
                     PSSSGAMSVNSVGMGQPATQGQVPGGTLPNPLNMLAPQTSQLPCPPVTQSPLHPTPPP
                     ASTAAGMPSLQHPTPPGMTPPQPAAPTQPSTPVSSGQTPTPTPGSVPSAAQTQSTPTV
                     QAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHTQPPGTPLSQAAASIDNRVPTPS
                     SVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPDPAESKGEPRSEMMEEDLQGSSQVKE
                     ETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSANGTASQSTSPSQPRKKIFKPEELRQ
                     ALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEP
                     WQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSP
                     QTLCCYGKQLCTIPRDAAYYSYQNSSPKYGLLADRYHFCEKCFTEIQGENVTLGDDPS
                     QPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKK
                     TGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVK
                     PGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVY
                     ISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHP
                     PDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWP
                     NVLEESIKELEQEEEERKKEESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRAN
                     KKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMD
                     GRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHC
                     TVCEDYDLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQS
                     LVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQEN
                     KCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPT
                     QQPSTPQTPQPPAQPQPSPVNMSPAGFPSVARTQPPTIVSAGKPTNQVPAPPPPAQPP
                     PAAVEAARQIEREAQQQQHLYRANINNGMPPGRAGMGTPGSQMAPVGLNVPRPNQVSG
                     PVMSSMPPGQWQQAPIPQQQPMPGMPRPVMSMQAQAAVAGPRMPNVQPPRSISPSALQ
                     DLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPG
                     MQPQPGMHQQPSLQNLNAMQAGVPRPGVPPPQQAMGGLNPQGQALNIMNPGHNPNMAN
                     MNPQYREMVRRQLLQHQQQQQQQQQQQQQQQQQQSSASLAGGMAGHSQFQQPQGPGGY
                     APAMQQQRMQQHLPIQGSSMGQMAAPMGQLGQMGQPGLGADSTPNIQQALQQRILQQQ
                     QMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQ
                     PPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSMDQGHLGNPEQSAMLPQLNTP
                     NRSALSSELSLVGDTTGDTLEKFVEGL"
ORIGIN      
        1 tcattaagtg gggcgcgcgc ggtggggggg cagcgaggcg gcggcggcgg taccaccatg
       61 ttcccgggcg ccgcctgagc cgcggggccg ggcgccgtcg ctgccagccg ggcccgcgga
      121 ggcggccggg ccgcttgggt gcccgggccg cggagtgtcg cgctcgggag gcgggcaggg
      181 gatgaggggg ccgcggccgg cggcggcggc ggcggccggg ggcgggcggt gagcgctgcg
      241 gggcgctgtt gctgaggctg agatttggcc gccgcctccc ccacccggcc tgcgccctcc
      301 gcggcccggc ccgcgctcct gcgctcgctc ttcgctggct agcctgctcg ctgccgccgg
      361 cccgaccccc gtccgggccg cgtcgcgccg cccgcgctta gggctgtttc cgcgagcagg
      421 tgaagatggc cgagaacttg ctggacggac cgcccaaccc caaacgagcc aaactcagct
      481 cgcccggctt ctccgcgaat gacagcacag attttggatc attgtttgac ttggaaaatg
      541 atcttcctga tgagctgatc cccaatggag aattaagcct tttaaacagt gggaaccttg
      601 ttccagatgc tgcgtccaaa cataaacaac tgtcagagct tcttagagga ggcagcggct
      661 ctagcatcac ccccgggata ggcaatgtga gtgccagcag ccctgtgcag cagggccttg
      721 gtggccaggc tcaggggcag ccgaacagta caagcatggc cagtttaggt gccatgggca
      781 agagccctct gaacccagga gactcatcaa cacccagcct gcccaaacag gcagccagca
      841 cctctgggcc cactccccct gcctcccaag cactgaatcc gcaagcacaa aagcaagtgg
      901 ggctggtgac cagtagtcct gccacatcac agactggacc tgggatctgc atgaatgcta
      961 acttcaacca gacccaccca ggccttctca atagtaactc tggccatagc ttaatgaatc
     1021 aggctcaaca agggcaagct caagtcatga atggatctct tggggctgct ggaagaggaa
     1081 ggggagctgg aatgccctac cctgctccag ccatgcaggg ggccacaagc agtgtgctgg
     1141 ctgagacttt gacacaggtt tctccacaaa tggctggcca tgctggactg aatacggcac
     1201 aggcaggagg catgaccaag atggggatga ctggtaacac aagtccgttt ggacaaccct
     1261 ttagtcaaac tggagggcag ccgatgggag ccactggagt gaaccctcag ttagccagca
     1321 aacagagcat ggtcaatagt ttgcctgctt ttcctacaga tatcaagaat acttcagtca
     1381 ccactgtgcc aaatatgtcc cagttgcaaa catcagtggg aattgtaccc gcacaaggaa
     1441 ttgcaaccgg ccccacagca gaccctgaga agcgcaaact gatacagcag cagctggttc
     1501 tactgcttca tgcccacaaa tgtcagcgac gagagcaagc gaatggagag gttcgggcct
     1561 gttctctccc acactgtcga accatgaaaa atgttttgaa tcacatgaca cattgtcagg
     1621 ctgggaaagc ctgccaagtt gcccattgtg catcttcacg acaaatcatc tctcattgga
     1681 agaactgcac acgacatgac tgtcctgttt gcctcccttt gaaaaatgcc agtgacaagc
     1741 gaaaccaaca aaccatcctg ggatctccag ctagtggaat tcaaaacaca attggttctg
     1801 ttggtgcagg gcaacagaat gccacttctt taagtaaccc aaatcccata gaccccagtt
     1861 ccatgcagcg ggcctatgct gctctaggac tcccctacat gaaccagcct cagacgcagc
     1921 tgcagcctca ggttcctggc cagcaaccag cacaacctcc agcccaccag cagatgagga
     1981 ctctgaatgc tctaggaaac aacccaatga gtattccagc aggaggaata acaacagatc
     2041 agcagccgcc aaacttgatt tcagaatcag ctcttccaac ttctttgggg gctaccaatc
     2101 cgctgatgaa tgatggctcc aactctggta gcattggaag cctcagcacg atacccacag
     2161 cagcacctcc ttccagcact ggtgttcgaa aaggctggca tgaacatgtg actcaggacc
     2221 tgcggagcca tctagtgcat aaactcgttc aagccatctt cccgactcct gacccggcag
     2281 ctctgaagga tcgccgcatg gagaacctgg ttgcctatgc taagaaagtg gagggagaca
     2341 tgtatgagtc tgctaatagc agggatgaat actatcattt attagcagag aaaatctata
     2401 aaatacaaaa agaactagaa gaaaaacgaa ggtcacgttt acataagcaa ggcatcctgg
     2461 gtaaccagcc agcattacca gctcctgggg ctcagccccc tgtgatccca ccaacccagt
     2521 ctgtgagacc tccaaatggg cccctgtctt tgccagtgaa tcgtgtgcag gtttctcaag
     2581 gaatgaattc atttaaccca atgtccctgg ggaacgtcca gttgccacag gcacccatgg
     2641 gacctcgcgc agcctccccc atgaaccact ctgtccagat gaacagcatg gcctcagttc
     2701 cgggtatggc catttctcct tcccggatgc ctcagcctcc caatatgatg ggcacccatg
     2761 ccaacaacat tatggcccag gcacctactc agaaccagtt tctgccacag aaccagtttc
     2821 catcatccag tggggcaatg agtgtgaaca gtgtaggcat ggggcagccc gcaacccagg
     2881 gccaggtgcc tggaggtaca cttcctaacc ctctgaacat gctggcgccc cagaccagcc
     2941 agcttccttg cccaccagtg acacagtcac ctttgcaccc gactccacct cctgcttcca
     3001 cagctgctgg catgccctct ctccagcatc cgacaccacc agggatgacc cctccccagc
     3061 cagcagctcc cactcagcca tccactcctg tgtcatctgg gcagactcct accccaactc
     3121 ctggctcagt gcccagtgct gcccaaacac agagcacccc aacagtgcag gcagcagcac
     3181 aggctcaggt gaccccacag cctcagactc cagtgcagcc accatctgtg gccactcctc
     3241 agtcatcaca gcagcaacca acgcctgtgc atactcagcc tcctggcaca ccgctttctc
     3301 aggcagcagc cagcattgat aatagagtcc ctactccctc ctctgtgacc agtgctgaaa
     3361 ccagttccca gcagccagga cctgatgtgc ccatgctgga aatgaagaca gaggtgcaga
     3421 cagatgatgc tgaacctgat cctgctgaat ccaaggggga accccgctct gagatgatgg
     3481 aagaggattt acaaggttct tcccaagtaa aagaagaaac agatacaaca gagcagaagt
     3541 cagaaccaat ggaagtagaa gaaaagaaac ccgaagtaaa agtggaagct aaagaggaag
     3601 aagagaacag tgctaacggc acagcctcac agtcaacatc cccttcccag ccacgcaaaa
     3661 aaatctttaa acctgaggag ctacgccagg cactcatgcc aactctagaa gcactctatc
     3721 gacaggaccc agagtctctg ccttttcggc agcctgtaga tcctcagctc ctaggaatcc
     3781 cagattattt tgatattgtg aagaatccta tggacctttc taccatcaag cgaaagctgg
     3841 acacagggca atatcaagaa ccctggcagt atgtggacga tgtctggctt atgttcaaca
     3901 atgcgtggct gtataatcgt aagacgtccc gggtatataa attttgcagt aaacttgcag
     3961 aggtctttga acaagaaatt gaccctgtca tgcagtctct tggatattgc tgtggccgaa
     4021 agtatgagtt ctccccacag actttgtgct gctatggaaa gcagctgtgt acaattcctc
     4081 gtgatgcagc ctactacagc tatcagaata gttcacccaa gtatggcctt cttgctgaca
     4141 ggtatcattt ctgtgagaag tgtttcacag agatccaggg cgagaatgtg accctgggtg
     4201 acgacccttc ccaacctcag acgacaattt ccaaggatca atttgaaaag aagaaaaatg
     4261 acaccttaga tcctgaaccc tttgttgact gcaaagagtg tggccggaag atgcatcaga
     4321 tttgcgttct acactatgac atcatttggc cttcaggttt tgtgtgtgac aactgcttga
     4381 agaaaactgg cagacctcgg aaagaaaaca aattcagtgc taagaggctg cagaccacac
     4441 ggttgggaaa ccatttggaa gaccgagtga acaagttttt gcggcgccag aatcaccctg
     4501 aagctgggga ggtttttgtc agagtggtgg ccagctcaga caagactgtg gaggtcaagc
     4561 caggaatgaa gtcaaggttt gtggattctg gagaaatgtc tgaatctttc ccatatcgta
     4621 ccaaagcact cttcgctttt gaggagattg atggagtcga tgtgtgcttt tttgggatgc
     4681 atgtacaaga atatggctcc gattgccccc cacctaatac aaggcgcgtc tatatatctt
     4741 atctggacag tattcatttc ttccggcccc gctgtctccg caccgctgtt taccatgaga
     4801 tcctcattgg atatctagag tatgtgaaga aattggggta tgtgacagga cacatttggg
     4861 cctgtccccc aagtgaagga gatgactaca tctttcattg ccacccccct gaccagaaaa
     4921 tccccaaacc aaaacgacta caggagtggt acaagaagat gctggacaag gcattcgcag
     4981 agaggatcat taacgactat aaggacatct tcaaacaagc gaacgaagac aggctcacga
     5041 gtgccaagga gttgccctat ttcgaaggag atttctggcc taatgtgttg gaagaaagca
     5101 ttaaggagct agaacaagaa gaagaagaaa ggaagaaaga agagagtact gcagcgagtg
     5161 agactcctga gggcagtcag ggtgacagca agaatgccaa gaaaaagaac aacaagaaga
     5221 ccaacaaaaa caaaagcagc attagccgcg ccaacaagaa gaagcccagc atgcccaatg
     5281 tttccaacga cctgtcgcag aagctgtatg ctaccatgga gaagcacaag gaggtcttct
     5341 ttgtgatcca cctgcatgct gggcctgtca tcagcactca gccccccatc gtggaccctg
     5401 atcccctgct tagctgtgac ctcatggacg ggcgggatgc cttcctcacc ctggccagag
     5461 acaagcactg ggagttctct tccttacgcc gctccaaatg gtccactctg tgcatgctgg
     5521 tggagctgca cacacagggc caggaccgct ttgtctatac ctgcaacgag tgcaaacacc
     5581 atgtagaaac acgctggcac tgcactgtgt gtgaggacta tgacctttgt atcaattgct
     5641 acaacacaaa gagccacacc cataagatgg tgaagtgggg gctaggccta gatgatgagg
     5701 gcagcagtca gggtgagcca cagtccaaga gcccccagga atcccggcgt ctcagcatcc
     5761 aacgctgcat ccagtccctg gtgcatgcct gccagtgtcg caatgccaac tgctcgctgc
     5821 catcttgcca gaagatgaag cgagtcgtgc agcacaccaa gggctgcaag cgcaagacta
     5881 atggaggctg cccagtgtgt aagcagctca ttgctctttg ctgctaccac gccaaacact
     5941 gccaagaaaa taaatgccct gtgcccttct gcctcaacat caaacacaag ctccgccagc
     6001 agcagatcca gcatcgcctg cagcaggctc agctcatgcg ccggcgaatg gcaaccatga
     6061 acacccgcaa tgtgcctcag cagagtttgc cttctcctac ctcagcacca cccgggactc
     6121 ctacacagca gcccagcaca ccccaaacac cacagccccc agcccagcct cagccttcac
     6181 ctgtaaacat gtcaccagct ggcttcccca gtgtagcccg gactcagccc cccacaatag
     6241 tgtctgctgg gaagcctacc aaccaggtgc cagctccccc accccctgcc cagcccccac
     6301 ctgcagcagt ggaagcagcc aggcaaattg aacgtgaggc ccagcagcag cagcacctgt
     6361 accgagcaaa catcaacaat ggcatgcccc cagggcgtgc aggtatgggg accccaggaa
     6421 gccagatggc tcctgtgggc ctgaatgtgc cccgtcccaa ccaagtcagt gggcctgtca
     6481 tgtctagcat gccacctggg cagtggcagc aggcacccat ccctcagcag cagccgatgc
     6541 caggcatgcc caggcctgta atgtccatgc aggcccaggc agcggtggct gggccacgga
     6601 tgcccaatgt acagccacca aggagcatct cgccaagtgc cctgcaagac ctgcttcgga
     6661 ccctaaagtc acccagctct cctcagcagc agcagcaggt gctgaacatc ctcaaatcaa
     6721 acccacagct aatggcagct ttcatcaaac agcgcacagc caagtatgtg gccaatcagc
     6781 ctggcatgca gccccagccc ggacttcaat cccagcctgg tatgcagccc cagcctggca
     6841 tgcaccagca gcccagcctg caaaacctga acgcaatgca agctggtgtg ccacggcctg
     6901 gtgtgcctcc accacagcag gcaatgggag gcctgaaccc ccagggtcag gctctgaata
     6961 tcatgaaccc gggacacaac cccaacatgg cgaacatgaa tccgcagtac cgagaaatgg
     7021 tgagaagaca gctgctacag caccaacagc agcagcagca gcagcagcag cagcagcagc
     7081 aacagcaaca gcaacaaagc agtgccagct tggccggggg catggcagga cacagccagt
     7141 tccagcagcc acaaggacct ggaggctacg ccccagccat gcagcagcaa cgcatgcaac
     7201 agcacctccc catccagggc agctccatgg gccagatggc tgctccaatg ggacaacttg
     7261 gccagatggg gcagcctggg ctaggggcag acagcacccc taatatccag caggccctgc
     7321 agcagcggat tctgcagcag cagcagatga agcaacaaat tgggtcacca ggccagccga
     7381 accccatgag cccccagcag cacatgctct caggacagcc acaggcttca catctccctg
     7441 gccagcagat cgccacatcc cttagtaacc aggtgcggtc tccagcccct gtgcagtctc
     7501 cacggcccca atcccaacct ccacattcca gcccgtcacc acggatacag ccccagcctt
     7561 caccacacca tgtttcaccc cagactggtt cccctcaccc tggacttgca gtcaccatgg
     7621 ccagctccat ggatcaggga cacctgggga accctgaaca gagtgcaatg ctcccccagc
     7681 tgaatacccc caacaggagc gcgctgtcca gtgaactgtc cctggttggt gataccacgg
     7741 gagacacgct agaaaagttt gtggagggct tgtagcatta tgagagcatt gggtgtttgt
     7801 ttttttgttt ttgttttggg gattttttgg gtcttttttt tttttttttc tccctctttt
     7861 tttttttttt tttttttttt tttggttttt tttttttt
//
