LOCUS       NP_001128093             561 aa            linear   ROD 24-JUN-2024
DEFINITION  cyclic AMP-responsive element-binding protein 5 [Rattus
            norvegicus].
ACCESSION   NP_001128093 XP_001060048 XP_575483
VERSION     NP_001128093.1
DBSOURCE    REFSEQ: accession NM_001134621.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 561)
  AUTHORS   Deng,B., Molina,J., Aubry,M.C., Sun,Z., Wang,L., Eckloff,B.W.,
            Vasmatzis,G., You,M., Wieben,E.D., Jen,J., Wigle,D.A. and Yang,P.
  TITLE     Clinical biomarkers of pulmonary carcinoid tumors in never smokers
            via profiling miRNA and target mRNA
  JOURNAL   Cell Biosci 4, 35 (2014)
   PUBMED   25105010
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 561)
  AUTHORS   Maekawa,T., Jin,W. and Ishii,S.
  TITLE     The role of ATF-2 family transcription factors in adipocyte
            differentiation: antiobesity effects of p38 inhibitors
  JOURNAL   Mol Cell Biol 30 (3), 613-625 (2010)
   PUBMED   19948881
REFERENCE   3  (residues 1 to 561)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (residues 1 to 561)
  AUTHORS   Zu,Y.L., Maekawa,T., Nomura,N., Nakata,T. and Ishii,S.
  TITLE     Regulation of trans-activating capacity of CRE-BPa by phorbol ester
            tumor promoter TPA
  JOURNAL   Oncogene 8 (10), 2749-2758 (1993)
   PUBMED   8378084
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474011.2.
            
            On or before Sep 4, 2008 this sequence version replaced
            XP_001060048.1, XP_575483.2.
FEATURES             Location/Qualifiers
     source          1..561
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     Protein         1..561
                     /product="cyclic AMP-responsive element-binding protein 5"
                     /calculated_mol_wt=62713
     Region          430..489
                     /region_name="bZIP_ATF2"
                     /note="Basic leucine zipper (bZIP) domain of Activating
                     Transcription Factor-2 (ATF-2) and similar proteins: a
                     DNA-binding and dimerization domain; cd14687"
                     /db_xref="CDD:269835"
     Region          430..489
                     /region_name="coiled coil"
                     /note="coiled coil [structural motif]"
                     /db_xref="CDD:269835"
     Site            order(431,435,437..439,442,444..446,448..450)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:269835"
     Site            order(449,456..457,459..460,463..464,467,470..471,474,
                     477..478,480..481,484..485,488..489)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:269835"
     CDS             1..561
                     /gene="Creb5"
                     /gene_synonym="RGD1566107"
                     /coded_by="NM_001134621.1:99..1784"
                     /db_xref="GeneID:500131"
                     /db_xref="RGD:1566107"
ORIGIN      
        1 mmqrnpgrkf anfhhfgqda wsprggrasl qgalsptgaq rplpsletry rlqliyeesk
       61 mnleqerpfv csapgcsqrf ptedhlmihr hkhemtlkfp siktdnmlsd qtptptrflk
      121 nceevglfse ldcsfehefr kaqeeesskr nismhntvgg tmtgpgahql gssrmpnhdt
      181 svviqqamps pqsssvitqa pstnrqigpv pgslssllhl hnrqrqpmpa smpgtlpnpt
      241 mpgssavlmp merqmsvnss imgmqgpnls npcaspqvqp mhseakmrlk aalthhpaam
      301 sngnmstigh mmemmgsrqd qtphhhmhsh phqhqtlpph hpyphqhqhp ahhphpqphh
      361 qqnhphhhsh shlhahpahh qtsphpplht gnqaqvspat qqmqptqtiq ppqptggrrr
      421 rvvdedpder rrkflernra aatrcrqkrk vwvmslekka eeltqtnmql qnevsmlkne
      481 vaqlkqlllt hkdcpitamq kesqgylspe ssppaspvpa csqqqviqhn tittsssvse
      541 vvgsstlsql tshrtdlnpi l
//
