LOCUS       NM_001007093            1617 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus cAMP responsive element binding protein 3-like 4
            (Creb3l4), transcript variant 1, mRNA.
ACCESSION   NM_001007093 XM_227391
VERSION     NM_001007093.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1617)
  AUTHORS   Wang,S. and Kaufman,R.J.
  TITLE     The impact of the unfolded protein response on human disease
  JOURNAL   J Cell Biol 197 (7), 857-867 (2012)
   PUBMED   22733998
  REMARK    Review article
REFERENCE   2  (bases 1 to 1617)
  AUTHORS   Labrie,C., Lessard,J., Ben Aicha,S., Savard,M.P., Pelletier,M.,
            Fournier,A., Lavergne,E. and Calvo,E.
  TITLE     Androgen-regulated transcription factor AIbZIP in prostate cancer
  JOURNAL   J Steroid Biochem Mol Biol 108 (3-5), 237-244 (2008)
   PUBMED   17933519
  REMARK    Review article
REFERENCE   3  (bases 1 to 1617)
  AUTHORS   Levesque,M.H., El-Alfy,M., Berger,L., Labrie,F. and Labrie,C.
  TITLE     Evaluation of AIbZIP and Cdc47 as markers for human prostatic
            diseases
  JOURNAL   Urology 69 (1), 196-201 (2007)
   PUBMED   17270658
REFERENCE   4  (bases 1 to 1617)
  AUTHORS   Stirling,J. and O'hare,P.
  TITLE     CREB4, a transmembrane bZip transcription factor and potential new
            substrate for regulation and cleavage by S1P
  JOURNAL   Mol Biol Cell 17 (1), 413-426 (2006)
   PUBMED   16236796
REFERENCE   5  (bases 1 to 1617)
  AUTHORS   Adham,I.M., Eck,T.J., Mierau,K., Muller,N., Sallam,M.A.,
            Paprotta,I., Schubert,S., Hoyer-Fender,S. and Engel,W.
  TITLE     Reduction of spermatogenesis but not fertility in Creb3l4-deficient
            mice
  JOURNAL   Mol Cell Biol 25 (17), 7657-7664 (2005)
   PUBMED   16107712
REFERENCE   6  (bases 1 to 1617)
  AUTHORS   Nagamori,I., Yabuta,N., Fujii,T., Tanaka,H., Yomogida,K.,
            Nishimune,Y. and Nojima,H.
  TITLE     Tisp40, a spermatid specific bZip transcription factor, functions
            by binding to the unfolded protein response element via the Rip
            pathway
  JOURNAL   Genes Cells 10 (6), 575-594 (2005)
   PUBMED   15938716
REFERENCE   7  (bases 1 to 1617)
  AUTHORS   Stelzer,G. and Don,J.
  TITLE     Atce1: a novel mouse cyclic adenosine
            3',5'-monophosphate-responsive element-binding protein-like gene
            exclusively expressed in postmeiotic spermatids
  JOURNAL   Endocrinology 143 (5), 1578-1588 (2002)
   PUBMED   11956138
REFERENCE   8  (bases 1 to 1617)
  AUTHORS   Qi,H., Fillion,C., Labrie,Y., Grenier,J., Fournier,A., Berger,L.,
            El-Alfy,M. and Labrie,C.
  TITLE     AIbZIP, a novel bZIP gene located on chromosome 1q21.3 that is
            highly expressed in prostate tumors and of which the expression is
            up-regulated by androgens in LNCaP human prostate cancer cells
  JOURNAL   Cancer Res 62 (3), 721-733 (2002)
   PUBMED   11830526
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Oct 5, 2022 this sequence version replaced NM_001007093.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY750875.1, SRR22582416.892387.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676784, SAMN16676785
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-367               JAXUCZ010000002.1  177993119-177993485 c
            368-602             JAXUCZ010000002.1  177992602-177992836 c
            603-724             JAXUCZ010000002.1  177992321-177992442 c
            725-817             JAXUCZ010000002.1  177989393-177989485 c
            818-924             JAXUCZ010000002.1  177989155-177989261 c
            925-993             JAXUCZ010000002.1  177988995-177989063 c
            994-1078            JAXUCZ010000002.1  177988829-177988913 c
            1079-1175           JAXUCZ010000002.1  177988554-177988650 c
            1176-1617           JAXUCZ010000002.1  177987981-177988422 c
FEATURES             Location/Qualifiers
     source          1..1617
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1617
                     /gene="Creb3l4"
                     /gene_synonym="AIbZIP"
                     /note="cAMP responsive element binding protein 3-like 4"
                     /db_xref="GeneID:310616"
                     /db_xref="RGD:1359278"
     exon            1..367
                     /gene="Creb3l4"
                     /gene_synonym="AIbZIP"
                     /inference="alignment:Splign:2.1.0"
     CDS             266..1369
                     /gene="Creb3l4"
                     /gene_synonym="AIbZIP"
                     /note="isoform 1 is encoded by transcript variant 1;
                     cyclic AMP-responsive element-binding protein 3-like
                     protein 4; androgen-induced bZIP protein; androgen-induced
                     basic leucine zipper protein; cAMP-responsive
                     element-binding protein 3-like protein 4"
                     /codon_start=1
                     /product="cyclic AMP-responsive element-binding protein
                     3-like protein 4 isoform 1"
                     /protein_id="NP_001007094.1"
                     /db_xref="GeneID:310616"
                     /db_xref="RGD:1359278"
                     /translation="MELGCPELLEPPEDIFSTGSFLELGFNGPPSKVPGLQKSESDDF
                     LNLFIDPNMIRCSETSPGSDSGVSEDPGSPAPQAPSSPALYEVVYEAGALQGTQREAG
                     PTFGLISIQIDQWSPAFMVPGACTVSDLPSEAHRHILPRVSTIAPPPPAALLSCQRLF
                     LTDEEKHLLGQEGVTLPSHLPLTKAEERILKKIRRKIRNKQSAQDSRRRKKEYIDGLE
                     SRVAACSEQNQKLQRKVQELERQNISLVAQVHQLQKFTAQTSSRAAQTSTCVLILLFS
                     LALIILPSFSPFQSQPEARSEGYQLHGVISRNILTHEDMTESPESPVLKANLEELPQV
                     PATNGSTKMAHLKMRVKARPTGPIRGMVHADEM"
     exon            368..602
                     /gene="Creb3l4"
                     /gene_synonym="AIbZIP"
                     /inference="alignment:Splign:2.1.0"
     exon            603..724
                     /gene="Creb3l4"
                     /gene_synonym="AIbZIP"
                     /inference="alignment:Splign:2.1.0"
     exon            725..817
                     /gene="Creb3l4"
                     /gene_synonym="AIbZIP"
                     /inference="alignment:Splign:2.1.0"
     exon            818..924
                     /gene="Creb3l4"
                     /gene_synonym="AIbZIP"
                     /inference="alignment:Splign:2.1.0"
     exon            925..993
                     /gene="Creb3l4"
                     /gene_synonym="AIbZIP"
                     /inference="alignment:Splign:2.1.0"
     exon            994..1078
                     /gene="Creb3l4"
                     /gene_synonym="AIbZIP"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1175
                     /gene="Creb3l4"
                     /gene_synonym="AIbZIP"
                     /inference="alignment:Splign:2.1.0"
     exon            1176..1617
                     /gene="Creb3l4"
                     /gene_synonym="AIbZIP"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtagtgtttg gggcttcagc gggctaggct ggtttggcag gacaaagctc tctcaataac
       61 aattaaaaaa aaaaaaaaag gtaataccca atgggactat ttttctgaac ccaaaagata
      121 agacctgaag tgtgttctcc tgcaaggggc tgcctcgtgt aagcagagga aaggagtaac
      181 ggagagaatg cagaggaacc agtagcttcc gagggcagcc accaccttcc ttctataact
      241 ttccttctca tcttccggca gaagcatgga gctcgggtgc cctgagttgc tggaaccccc
      301 agaagatatc ttctcgacag gatctttcct ggagctggga tttaatggtc ccccgtcaaa
      361 ggtgccgggc cttcagaaga gcgagtctga tgatttcctg aacctcttta tcgatcccaa
      421 tatgatacgc tgctcagaaa catctcctgg tagtgacagt ggggtctctg aagatcctgg
      481 ctcccctgcc ccacaggcac ccagttcccc agccctctat gaagttgtct atgaggcagg
      541 agccctacag ggaacccagc gggaagctgg gccaaccttc ggactcatct ccatccagat
      601 agatcagtgg agccctgcat ttatggtacc tggtgcctgc acagtcagtg atctgccctc
      661 tgaagctcat agacacatcc tgcctagagt cagcaccata gccccaccac ctcctgcagc
      721 cctgctgtcc tgccaacgtc tgttcctgac agatgaagaa aagcatctgc tgggacaaga
      781 aggggttact ctgccctctc acctgcccct caccaaggca gaggagagaa tactcaagaa
      841 gatcaggagg aaaatccgca acaagcagtc agctcaggac agccggcgga ggaagaaaga
      901 atacatagat gggctggaga gcagagtggc agcctgttct gagcagaacc agaaactgca
      961 gagaaaggtc caggagctgg agaggcagaa catctcgttg gtggcgcagg tccatcagtt
     1021 acagaagttc actgctcaga cctccagcag agctgcccag accagcacct gtgttctgat
     1081 tcttcttttt tcgttggctc tcatcatcct gcccagcttc agcccctttc agagtcaacc
     1141 agaagctagg tctgagggtt atcagcttca tggagtcatt tccagaaata tcttgactca
     1201 tgaggacatg acagaaagcc cggagagtcc agtgctaaag gccaacctgg aggagctacc
     1261 tcaagtccca gccacaaatg gctcaacaaa gatggctcat ctgaagatgc gagtgaaggc
     1321 cagacccact gggccgatca ggggaatggt gcatgcagat gagatgtaac tacacaagaa
     1381 gacacccagg cttccctgtc acctttcatc aggttcccat tgaggagtcc acagccctgg
     1441 agttctgact tactcagaac acaactggag acttctgtcc cctaaggcca ggctgcctat
     1501 gtggcagggt acctcaaata cttctgtcat acatttgtga tttcatttct tctctgtgga
     1561 taaggtcagg gggagaaaag gtttgacttg gaaataaact tcctagctca aattcta
//
