LOCUS       NM_017244                772 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus cellular retinoic acid binding protein 2
            (Crabp2), mRNA.
ACCESSION   NM_017244 XM_001073561
VERSION     NM_017244.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 772)
  AUTHORS   Zhang,W., Vreeland,A.C. and Noy,N.
  TITLE     RNA-binding protein HuR regulates nuclear import of protein
  JOURNAL   J Cell Sci 129 (21), 4025-4033 (2016)
   PUBMED   27609837
REFERENCE   2  (bases 1 to 772)
  AUTHORS   Napoli,J.L.
  TITLE     Physiological insights into all-trans-retinoic acid biosynthesis
  JOURNAL   Biochim Biophys Acta 1821 (1), 152-167 (2012)
   PUBMED   21621639
  REMARK    Review article
REFERENCE   3  (bases 1 to 772)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (bases 1 to 772)
  AUTHORS   Dieplinger,B., Schiefermeier,N., Juchum-Pasquazzo,M., Gstir,R.,
            Huber,L.A., Klimaschewski,L. and Vietor,I.
  TITLE     The transcriptional corepressor TPA-inducible sequence 7 regulates
            adult axon growth through cellular retinoic acid binding protein II
            expression
  JOURNAL   Eur J Neurosci 26 (12), 3358-3367 (2007)
   PUBMED   18052984
REFERENCE   5  (bases 1 to 772)
  AUTHORS   Flajollet,S., Lefebvre,B., Rachez,C. and Lefebvre,P.
  TITLE     Distinct roles of the steroid receptor coactivator 1 and of MED1 in
            retinoid-induced transcription and cellular differentiation
  JOURNAL   J Biol Chem 281 (29), 20338-20348 (2006)
   PUBMED   16723356
REFERENCE   6  (bases 1 to 772)
  AUTHORS   Despouy,G., Bastie,J.N., Deshaies,S., Balitrand,N., Mazharian,A.,
            Rochette-Egly,C., Chomienne,C. and Delva,L.
  TITLE     Cyclin D3 is a cofactor of retinoic acid receptors, modulating
            their activity in the presence of cellular retinoic acid-binding
            protein II
  JOURNAL   J Biol Chem 278 (8), 6355-6362 (2003)
   PUBMED   12482873
REFERENCE   7  (bases 1 to 772)
  AUTHORS   Yamamoto,M., Drager,U.C., Ong,D.E. and McCaffery,P.
  TITLE     Retinoid-binding proteins in the cerebellum and choroid plexus and
            their relationship to regionalized retinoic acid synthesis and
            degradation
  JOURNAL   Eur J Biochem 257 (2), 344-350 (1998)
   PUBMED   9826179
REFERENCE   8  (bases 1 to 772)
  AUTHORS   Bucco,R.A., Melner,M.H., Gordon,D.S., Leers-Sucheta,S. and Ong,D.E.
  TITLE     Inducible expression of cellular retinoic acid-binding protein II
            in rat ovary: gonadotropin regulation during luteal development
  JOURNAL   Endocrinology 136 (6), 2730-2740 (1995)
   PUBMED   7750498
REFERENCE   9  (bases 1 to 772)
  AUTHORS   Fawcett,D., Pasceri,P., Fraser,R., Colbert,M., Rossant,J. and
            Giguere,V.
  TITLE     Postaxial polydactyly in forelimbs of CRABP-II mutant mice
  JOURNAL   Development 121 (3), 671-679 (1995)
   PUBMED   7720575
REFERENCE   10 (bases 1 to 772)
  AUTHORS   Chapman,J.M. and Curley,R.W. Jr.
  TITLE     Affinity purification of retinoic acid-binding proteins using
            immobilized 4-(2-hydroxyethoxy)retinoic acid
  JOURNAL   Protein Expr Purif 1 (1), 63-69 (1990)
   PUBMED   1967079
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Nov 27, 2020 this sequence version replaced NM_017244.1.
            
            Sequence Note: This sequence has been modified as follows: removed
            28 bp suspected to be vector contamination from the 3' end.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U23407.1, CO403862.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-172               JAXUCZ010000002.1  175714862-175715033
            173-354             JAXUCZ010000002.1  175718076-175718257
            355-471             JAXUCZ010000002.1  175718447-175718563
            472-772             JAXUCZ010000002.1  175718908-175719208
FEATURES             Location/Qualifiers
     source          1..772
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..772
                     /gene="Crabp2"
                     /note="cellular retinoic acid binding protein 2"
                     /db_xref="GeneID:29563"
                     /db_xref="RGD:62070"
     exon            1..172
                     /gene="Crabp2"
                     /inference="alignment:Splign:2.1.0"
     CDS             103..522
                     /gene="Crabp2"
                     /note="cellular lipid-binding protein; cellular retinoic
                     acid-binding protein II; CRABP-II; cellular retinoic
                     acid-binding protein 2-like"
                     /codon_start=1
                     /product="cellular retinoic acid-binding protein 2"
                     /protein_id="NP_058940.1"
                     /db_xref="GeneID:29563"
                     /db_xref="RGD:62070"
                     /translation="MPNFSGNWKIIRSENFEEMLKALGVNMMMRKIAVAAASKPAVEI
                     KQENDDTFYIKTSTTVRTTEINFKIGEEFEEQTVDGRPCKSLVKWESENKMVCEQRLL
                     KGEGPKTSWSRELTNDGELILTMTADDVVCTRVYVRE"
     exon            173..354
                     /gene="Crabp2"
                     /inference="alignment:Splign:2.1.0"
     exon            355..471
                     /gene="Crabp2"
                     /inference="alignment:Splign:2.1.0"
     exon            472..772
                     /gene="Crabp2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gatctgttct gcaaagggga cagcaaggta cctttaggct aaaggactcg gcgtccagta
       61 ttctagttga agatctaaag agaaagccac cttgctgcca ctatgcctaa cttttctggc
      121 aactggaaga tcatccgatc ggaaaacttt gaagaaatgc taaaagctct gggggtgaac
      181 atgatgatga ggaagattgc tgtggctgca gcctccaagc cagcagtgga gatcaaacag
      241 gagaatgatg acactttcta catcaaaacc tccaccactg ttcgaaccac ggagattaac
      301 ttcaagatcg gggaggaatt tgaggagcag actgtggatg ggagaccctg taagagtttg
      361 gtgaaatggg agagtgaaaa caaaatggtg tgcgaacaga ggcttctgaa gggggagggc
      421 cccaaaacct cctggagccg agaactgacc aatgatggag agctaatcct gaccatgaca
      481 gcagacgacg ttgtatgcac cagggtctac gtccgagagt gagtgcctat gtccaagaac
      541 ttcttctgga ggccacaaac ctccctccca tgtccatttt acaaactagc tctcccctta
      601 ctcctgaggg tcactctcta tgccagagag gggcagacta ccaaagctca gaacccttcc
      661 atttgcctgg tcagaagtcc cagctccata ccaggatcct tcctggaaga gactgtctct
      721 ctggcctcta ctctttatcc ttgtagtcca agtgatttag aatatttatt gg
//
