LOCUS       NM_001105716             755 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cellular retinoic acid binding protein 1
            (Crabp1), mRNA.
ACCESSION   NM_001105716 XM_001072647 XM_236253
VERSION     NM_001105716.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Touyarot,K., Bonhomme,D., Roux,P., Alfos,S., Lafenetre,P.,
            Richard,E., Higueret,P. and Pallet,V.
  TITLE     A mid-life vitamin A supplementation prevents age-related spatial
            memory deficits and hippocampal neurogenesis alterations through
            CRABP-I
  JOURNAL   PLoS One 8 (8), e72101 (2013)
   PUBMED   23977218
  REMARK    GeneRIF: CRABP-I expression controls the intracellular availability
            of retinoic acid and may be an important regulator of neuronal
            differentiation processes in the aged hippocampus.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 755)
  AUTHORS   Napoli,J.L.
  TITLE     Physiological insights into all-trans-retinoic acid biosynthesis
  JOURNAL   Biochim Biophys Acta 1821 (1), 152-167 (2012)
   PUBMED   21621639
  REMARK    Review article
REFERENCE   3  (bases 1 to 755)
  AUTHORS   Rocha,S.F., Lopes,S.S., Gossler,A. and Henrique,D.
  TITLE     Dll1 and Dll4 function sequentially in the retina and pV2 domain of
            the spinal cord to regulate neurogenesis and create cell diversity
  JOURNAL   Dev Biol 328 (1), 54-65 (2009)
   PUBMED   19389377
REFERENCE   4  (bases 1 to 755)
  AUTHORS   Asson-Batres,M.A., Ahmad,O. and Smith,W.B.
  TITLE     Expression of the cellular retinoic acid binding proteins, type II
            and type I, in mature rat olfactory epithelium
  JOURNAL   Cell Tissue Res 312 (1), 9-19 (2003)
   PUBMED   12684871
  REMARK    GeneRIF: both CRABP II and CRABP I proteins and the mRNAs that
            encode them are present in postnatal rat olfactory epithelium
REFERENCE   5  (bases 1 to 755)
  AUTHORS   Chapman,J.M. and Curley,R.W. Jr.
  TITLE     Affinity purification of retinoic acid-binding proteins using
            immobilized 4-(2-hydroxyethoxy)retinoic acid
  JOURNAL   Protein Expr Purif 1 (1), 63-69 (1990)
   PUBMED   1967079
REFERENCE   6  (bases 1 to 755)
  AUTHORS   Eriksson,U., Sundelin,J., Rask,L. and Peterson,P.A.
  TITLE     The NH2-terminal amino acid sequence of cellular retinoic-acid
            binding protein from rat testis
  JOURNAL   FEBS Lett 135 (1), 70-72 (1981)
   PUBMED   6274689
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473975.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_001072647.1, XM_236253.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132269 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..755
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..755
                     /gene="Crabp1"
                     /note="cellular retinoic acid binding protein 1"
                     /db_xref="GeneID:25061"
                     /db_xref="RGD:2400"
     exon            1..177
                     /gene="Crabp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             108..521
                     /gene="Crabp1"
                     /note="CRABP-I; cellular retinoic acid-binding protein I"
                     /codon_start=1
                     /product="cellular retinoic acid-binding protein 1"
                     /protein_id="NP_001099186.1"
                     /db_xref="GeneID:25061"
                     /db_xref="RGD:2400"
                     /translation="MPNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEI
                     RQDGDQFYIKTSTTVRTTEINFKVGEGFEEETVDGRKCRSLPTWENENKIHCTQTLLE
                     GDGPKTYWTRELANDELILTFGADDVVCTRIYVRE"
     exon            178..356
                     /gene="Crabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            357..470
                     /gene="Crabp1"
                     /inference="alignment:Splign:2.1.0"
     exon            471..755
                     /gene="Crabp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtctctctct ctgcaacgcc gcgtgcgacc gctcctcagc agaggtgggt gcctgccgct
       61 gccttcgcgc cgccactacc gccgctaccg ccaacaccac cgccaccatg cccaacttcg
      121 ccggtacctg gaagatgcgc agcagcgaga atttcgacga gctcctcaag gctctgggtg
      181 tgaacgccat gctgaggaag gtggcagtgg cggctgcgtc caagccgcac gtggagatcc
      241 gccaggacgg ggatcagttc tacatcaaga catccactac ggtgcgcacc acggagatca
      301 acttcaaggt cggagagggc ttcgaggagg agacggtgga cggacgcaag tgcaggagtt
      361 tacccacttg ggagaatgag aacaagattc actgcacgca gacgcttctt gagggggatg
      421 gccccaaaac ttactggacc cgagagctgg ccaacgatga gctaatcctg acatttggcg
      481 ccgatgatgt ggtgtgcaca agaatttatg tccgggagta aaggtggcca gcttgttctg
      541 ctttcatggc aggatacaag ttcccacgag gagcacgtcg tggtcccgca ctgccagtgg
      601 gtctttcctc cacacacctc tcccccatga atattaggca accccatttt ccctatgaca
      661 atgttgtagt accctcccct caggcccttg ttgcctcccg catccctggt ttggcatctg
      721 catgattgta ccagtcatta aactgtttgg atgca
//
