LOCUS       NM_001399757            3565 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus cleavage and polyadenylation specific factor 7
            (Cpsf7), transcript variant 1, mRNA.
ACCESSION   NM_001399757 XM_006231062
VERSION     NM_001399757.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3565)
  AUTHORS   Zhu,Y., Wang,X., Forouzmand,E., Jeong,J., Qiao,F., Sowd,G.A.,
            Engelman,A.N., Xie,X., Hertel,K.J. and Shi,Y.
  TITLE     Molecular Mechanisms for CFIm-Mediated Regulation of mRNA
            Alternative Polyadenylation
  JOURNAL   Mol Cell 69 (1), 62-74 (2018)
   PUBMED   29276085
REFERENCE   2  (bases 1 to 3565)
  AUTHORS   Gruber,A.R., Martin,G., Keller,W. and Zavolan,M.
  TITLE     Means to an end: mechanisms of alternative polyadenylation of
            messenger RNA precursors
  JOURNAL   Wiley Interdiscip Rev RNA 5 (2), 183-196 (2014)
   PUBMED   24243805
  REMARK    Review article
REFERENCE   3  (bases 1 to 3565)
  AUTHORS   Gruber,A.R., Martin,G., Keller,W. and Zavolan,M.
  TITLE     Cleavage factor Im is a key regulator of 3' UTR length
  JOURNAL   RNA Biol 9 (12), 1405-1412 (2012)
   PUBMED   23187700
REFERENCE   4  (bases 1 to 3565)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (bases 1 to 3565)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 3565)
  AUTHORS   Chan,S., Choi,E.A. and Shi,Y.
  TITLE     Pre-mRNA 3'-end processing complex assembly and function
  JOURNAL   Wiley Interdiscip Rev RNA 2 (3), 321-335 (2011)
   PUBMED   21957020
  REMARK    Review article
REFERENCE   7  (bases 1 to 3565)
  AUTHORS   Kim,S., Yamamoto,J., Chen,Y., Aida,M., Wada,T., Handa,H. and
            Yamaguchi,Y.
  TITLE     Evidence that cleavage factor Im is a heterotetrameric protein
            complex controlling alternative polyadenylation
  JOURNAL   Genes Cells 15 (9), 1003-1013 (2010)
   PUBMED   20695905
REFERENCE   8  (bases 1 to 3565)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   9  (bases 1 to 3565)
  AUTHORS   Ruepp,M.D., Aringhieri,C., Vivarelli,S., Cardinale,S., Paro,S.,
            Schumperli,D. and Barabino,S.M.
  TITLE     Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in
            mRNA export
  JOURNAL   Mol Biol Cell 20 (24), 5211-5223 (2009)
   PUBMED   19864460
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 13, 2022 this sequence version replaced XM_006231062.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643285.5331.1,
                                           SRR26360172.2921006.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-62                JAXUCZ010000001.1  216592790-216592851
            63-171              JAXUCZ010000001.1  216593484-216593592
            172-390             JAXUCZ010000001.1  216599370-216599588
            391-494             JAXUCZ010000001.1  216600403-216600506
            495-667             JAXUCZ010000001.1  216600878-216601050
            668-1082            JAXUCZ010000001.1  216603332-216603746
            1083-1201           JAXUCZ010000001.1  216605177-216605295
            1202-1370           JAXUCZ010000001.1  216607763-216607931
            1371-1538           JAXUCZ010000001.1  216608561-216608728
            1539-3565           JAXUCZ010000001.1  216614834-216616860
FEATURES             Location/Qualifiers
     source          1..3565
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..3565
                     /gene="Cpsf7"
                     /gene_synonym="RGD1305441"
                     /note="cleavage and polyadenylation specific factor 7"
                     /db_xref="GeneID:365407"
                     /db_xref="RGD:1305441"
     exon            1..62
                     /gene="Cpsf7"
                     /gene_synonym="RGD1305441"
                     /inference="alignment:Splign:2.1.0"
     exon            63..171
                     /gene="Cpsf7"
                     /gene_synonym="RGD1305441"
                     /inference="alignment:Splign:2.1.0"
     CDS             118..1533
                     /gene="Cpsf7"
                     /gene_synonym="RGD1305441"
                     /note="isoform 1 is encoded by transcript variant 1;
                     cleavage and polyadenylation specificity factor subunit 7;
                     cleavage and polyadenylation specific factor 7, 59kDa"
                     /codon_start=1
                     /product="cleavage and polyadenylation specificity factor
                     subunit 7 isoform 1"
                     /protein_id="NP_001386686.1"
                     /db_xref="GeneID:365407"
                     /db_xref="RGD:1305441"
                     /translation="MSEGVDLIDIYADEEFNQDSEFNNTDQIDLYDDVLTAASQPSDD
                     RSSSTEPPPPVRQEPAPKPNNKTPAILYTYSGLRSRRAAVYVGSFSWWTTDQQLIQVI
                     RSIGVYDVVELKFAENRANGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPA
                     TRQNLSQFEAQARKRECVRVPRGGIPPRAHSRDSSDSADGRATPSENLVPSSARVDKP
                     PSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPRLPPH
                     LAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASTPYNHHGSRDSGPLPSTVSE
                     AEFEEIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVL
                     ISSLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDD
                     YFQERNREHERHRDRERDRHH"
     exon            172..390
                     /gene="Cpsf7"
                     /gene_synonym="RGD1305441"
                     /inference="alignment:Splign:2.1.0"
     exon            391..494
                     /gene="Cpsf7"
                     /gene_synonym="RGD1305441"
                     /inference="alignment:Splign:2.1.0"
     exon            495..667
                     /gene="Cpsf7"
                     /gene_synonym="RGD1305441"
                     /inference="alignment:Splign:2.1.0"
     exon            668..1082
                     /gene="Cpsf7"
                     /gene_synonym="RGD1305441"
                     /inference="alignment:Splign:2.1.0"
     exon            1083..1201
                     /gene="Cpsf7"
                     /gene_synonym="RGD1305441"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..1370
                     /gene="Cpsf7"
                     /gene_synonym="RGD1305441"
                     /inference="alignment:Splign:2.1.0"
     exon            1371..1538
                     /gene="Cpsf7"
                     /gene_synonym="RGD1305441"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..3565
                     /gene="Cpsf7"
                     /gene_synonym="RGD1305441"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagagcggt tcgcgcgctt cgggcctagt cgggactctc cgcggccgcc gccatattcc
       61 cgtggcatct ttcttacttt gtccgttctc cgggctcgag agcgtgtttc cggagccatg
      121 tcagaaggag tggatttgat tgatatatac gctgatgaag agttcaatca ggactcggag
      181 ttcaacaaca cagatcagat tgacctatat gatgatgtgc tgacggcggc ctcacagccc
      241 tcggatgaca gaagcagtag cacagaacca ccccctcctg tccgccagga gccagctccc
      301 aaaccaaaca acaagacccc tgcaattctg tacacataca gtggcctgcg gagtcggcga
      361 gcagctgtct atgtaggcag tttctcctgg tggaccacag accagcagct gatccaggtt
      421 attcgctcta taggagtcta tgatgtggtg gagttgaaat ttgcagagaa ccgtgcaaat
      481 ggccagtcta aagggtatgc tgaggtggtg gtagcctctg aaaattctgt ccacaaattg
      541 ctggaactct taccaggaaa agttcttaat ggagaaaaag tagatgtgag gccagccact
      601 cggcagaact tatcacaatt tgaggctcag gctcggaaac gtgagtgcgt ccgagtccca
      661 agagggggaa tacctccacg ggcccactcc cgagattcta gtgattctgc tgatggacgg
      721 gcaaccccct ctgagaatct tgtaccctca tctgctcgtg tggataagcc ccccagcgtg
      781 ttgccctact ttaaccgtcc tccttcagcc cttcccctaa tgggtctgcc cccaccccca
      841 attccacccc caccacctct ctcctcaagc tttggtgtcc ctcctcctcc tcctggtatc
      901 cactaccagc atctcatgcc cccccctcct cgattacctc ctcatctggc tgtacctccc
      961 cctggggcca tcccaccagc ccttcacctc aatccagcct tcttcccccc accaaatgct
     1021 acagtggggc ctccaccaga tacttacatg aaggcctcta caccctataa ccaccatggc
     1081 agccgagatt caggccctct accgtctaca gtgagtgaag ctgaatttga agagataatg
     1141 aagcgaaaca gagcaatttc cagcagtgcc atttccaaag cagtgtctgg agctagtgca
     1201 ggggattaca gtgacgccat tgagacacta ctcacagcca ttgcagttat caaacagtcc
     1261 cgagtcgcca atgatgagcg ttgtcgggtc ctcatctctt cacttaagga ctgtcttcat
     1321 ggcatagagg ccaagtctta cagtgtgggt gccagtggaa gctcttctag gaaaagacat
     1381 cggtcaaggg agaggtcacc cagccggtcc cgagagagta gcagaaggca ccgagacttg
     1441 cttcataatg aagaccgaca tgatgattat ttccaagaaa ggaaccggga gcatgagaga
     1501 caccgggata gagaacggga ccggcaccac tgagaaagga gtctgggtgg aagcaaattg
     1561 tttttaatgg acttgcatct cctcaccttg atcaggacta aaggacggag gccgctccac
     1621 cccttcccct tcttccaaac ccctaacttc ctccaggcaa aaccctctgc cctgcaggat
     1681 tgaagatggc ttggcagccc tcccaatccc acaccttctg tttgccatgg gggaagaacc
     1741 taaagacttg ctggggtagt gaacgagggc atacaggaag acagcaacat gtccagccca
     1801 tagtctccat agagaatggt gctttgtcca aggaaacctg agtttctgat tgcccagaag
     1861 cagtcagtgg tgaggttact atgagaaaat ttccttccca gagaaaatgg atcctctatg
     1921 tggggtctta ggaaagtgac tgggtgtgcc aaaaatgccc agggttctgc cctcagtact
     1981 agatttgatg gggccaaaag ggtccaaacc ctgctaacat accactttgt tcaactcctg
     2041 tactttccta gccagttgag gagggaccat gagaacagaa actaccttgt gacaagaaac
     2101 gtgttctcag ttttctcctc acgtgttgat ggtttatttc catggcctcc tagagggctg
     2161 aatccttttg actccttact atctgactcc tcagtggact tgcccctctg aaacagaacc
     2221 caggaagctt cggctatctg ccggaagcct aggccagcca gataccacca tttgctgctt
     2281 taggcttgtc tgtttgttgc aataaccagc tcttaggtat ttcctttccc caaggctttc
     2341 catttaacat ggaatccttc cccaagaagg cttcttcctt gttttagagg aaggtactgc
     2401 ctttgggact tagggatgtc atgggacctc agtaactagg acccctagtt aataaagtac
     2461 cagaagtgtg gagaagagag caatttgagc agtatgtagc ctactcacat gggctctttt
     2521 gcaggttaat gtgagcatag gcttgcattt ccaaggtaca tactttgact taactgtgga
     2581 ataactcagc actaataggc aggtaaagtc aagactggtt tttgggggtt tcttttttgg
     2641 tgtttttgtt tttgttttta ttcctttgct ctgatacttc ccccgtcact ttgcctggag
     2701 gtgcttccag cctttaagaa ggagcagaga attggagctc agagttgtaa ggaccagcac
     2761 actagtggcc attttctgca caagcaaatg gaattgcttt tttcagcatc cagactgtga
     2821 taggttgctc ttgatggagg tagccacagt cctggagtac catagggtaa tgttccttca
     2881 gcagggcctg tgagatctaa tgtgaagaga gacacaacat gtgagatggg acttggtgtg
     2941 tgaggcatgg agtcattgga gactcttcag attcagaggg gagactgaat tggatgcttt
     3001 ctctcttctc ggcacacttc tgacagaccc cttcagtcac tgagggagtg cccccaaggt
     3061 tggagaggca cattcccttt ggacagaggc tacaagttgt agcttatttt cctgtcccct
     3121 aaaccaatcc ctattccatc aacatggcat cctgcctaat tttctaaggg ttaagtgata
     3181 tgcttattct tgaaagcaac tcgggtgtct ttttaaaaaa gaaaaaaatg aaaaaaaaaa
     3241 aaaaaggaaa gtgacagtta aggaaaaaca acatataaaa tatcagaaaa gctgtttacc
     3301 cagagaatta ttttctcccc acttttattt ttactcagtg acataatttt tagttttatt
     3361 cctcatagca aaaggagaaa agcatcccag tcctcaaaag gtcaaggccc cacccctgtt
     3421 gtcggtgatt tgtttgtctt tctgataggt tgagaattgt gtaataaact tgatgacgat
     3481 gtcaatcttt tatactgcat tgtatttttt tccttttgta acaaaatatt tttaaataat
     3541 aaatggggtg tgagctgttt acgga
//
