LOCUS       NM_001134705             492 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus cytochrome c oxidase subunit 7C (Cox7c), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_001134705
VERSION     NM_001134705.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Moutaoufik,M.T., Malty,R., Amin,S., Zhang,Q., Phanse,S.,
            Gagarinova,A., Zilocchi,M., Hoell,L., Minic,Z., Gagarinova,M.,
            Aoki,H., Stockwell,J., Jessulat,M., Goebels,F., Broderick,K.,
            Scott,N.E., Vlasblom,J., Musso,G., Prasad,B., Lamantea,E.,
            Garavaglia,B., Rajput,A., Murayama,K., Okazaki,Y., Foster,L.J.,
            Bader,G.D., Cayabyab,F.S. and Babu,M.
  TITLE     Rewiring of the Human Mitochondrial Interactome during Neuronal
            Reprogramming Reveals Regulators of the Respirasome and
            Neurogenesis
  JOURNAL   iScience 19, 1114-1132 (2019)
   PUBMED   31536960
REFERENCE   3  (bases 1 to 492)
  AUTHORS   Zong,S., Wu,M., Gu,J., Liu,T., Guo,R. and Yang,M.
  TITLE     Structure of the intact 14-subunit human cytochrome c oxidase
  JOURNAL   Cell Res 28 (10), 1026-1034 (2018)
   PUBMED   30030519
REFERENCE   4  (bases 1 to 492)
  AUTHORS   Armand-Ugon,M., Ansoleaga,B., Berjaoui,S. and Ferrer,I.
  TITLE     Reduced Mitochondrial Activity is Early and Steady in the
            Entorhinal Cortex but it is Mainly Unmodified in the Frontal Cortex
            in Alzheimer's Disease
  JOURNAL   Curr Alzheimer Res 14 (12), 1327-1334 (2017)
   PUBMED   28474567
REFERENCE   5  (bases 1 to 492)
  AUTHORS   Zhao,X., Leon,I.R., Bak,S., Mogensen,M., Wrzesinski,K., Hojlund,K.
            and Jensen,O.N.
  TITLE     Phosphoproteome analysis of functional mitochondria isolated from
            resting human muscle reveals extensive phosphorylation of inner
            membrane protein complexes and enzymes
  JOURNAL   Mol Cell Proteomics 10 (1), M110.000299 (2011)
   PUBMED   20833797
REFERENCE   6  (bases 1 to 492)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   7  (bases 1 to 492)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   8  (bases 1 to 492)
  AUTHORS   Schagger,H., Noack,H., Halangk,W., Brandt,U. and von Jagow,G.
  TITLE     Cytochrome-c oxidase in developing rat heart. Enzymic properties
            and amino-terminal sequences suggest identity of the fetal heart
            and the adult liver isoform
  JOURNAL   Eur J Biochem 230 (1), 235-241 (1995)
   PUBMED   7601105
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BI289576.1, BC166894.1 and BQ779631.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ221226.1, BE126484.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                BI289576.1         432-467             c
            37-347              BC166894.1         1-311
            348-492             BQ779631.1         1-145               c
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q11"
     gene            1..492
                     /gene="Cox7c"
                     /gene_synonym="Cox7c1"
                     /note="cytochrome c oxidase subunit 7C"
                     /db_xref="GeneID:100188937"
                     /db_xref="RGD:2300145"
     exon            1..216
                     /gene="Cox7c"
                     /gene_synonym="Cox7c1"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..333
                     /gene="Cox7c"
                     /gene_synonym="Cox7c1"
                     /EC_number="7.1.1.9"
                     /note="Cytochrome c oxidase polypeptide VIIc; Cytochrome c
                     oxidase polypeptide VIIIA; cytochrome c oxidase, subunit
                     VIIc"
                     /codon_start=1
                     /product="cytochrome c oxidase subunit 7C, mitochondrial"
                     /protein_id="NP_001128177.1"
                     /db_xref="GeneID:100188937"
                     /db_xref="RGD:2300145"
                     /translation="MLGQSIRRFTTSVVRRSHYEEGPGKNLPFSVENKWRLLLMMTVY
                     FGSGFAAPFFIVRHQLLKK"
     exon            217..359
                     /gene="Cox7c"
                     /gene_synonym="Cox7c1"
                     /inference="alignment:Splign:2.1.0"
     exon            360..478
                     /gene="Cox7c"
                     /gene_synonym="Cox7c1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagtccgtg ctgtagttcc catcttccct ttcggtcttc tcgttccgga tagcaaggtc
       61 gtgaagaaag tagggtgagg tggtacggtc atttcttctg ccttccgtct ctgcgactct
      121 cggagaactt ccagcagcag catgttgggc cagagtatcc ggaggttcac cacctccgtg
      181 gtgcgtcgca gccactatga ggagggtccg gggaagaatt tgccgttttc agtggaaaac
      241 aagtggcggt tactgcttat gatgaccgtg tactttggat ctggatttgc tgctcctttc
      301 tttatagtaa ggcaccagct acttaaaaaa taaggatatt taattcatcc cattaacaga
      361 atgaagaaag tttaagagat atgatctgga aattggatta aactcttgaa ctcttatact
      421 agaaaaaaat gtaaataaac taatgatata aatatttaat gcctcttctc tgccataaaa
      481 aaaaaaaaaa aa
//
