LOCUS       NM_022503                495 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus cytochrome c oxidase subunit 7A2 (Cox7a2), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_022503
VERSION     NM_022503.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 495)
  AUTHORS   Zong,S., Wu,M., Gu,J., Liu,T., Guo,R. and Yang,M.
  TITLE     Structure of the intact 14-subunit human cytochrome c oxidase
  JOURNAL   Cell Res 28 (10), 1026-1034 (2018)
   PUBMED   30030519
REFERENCE   3  (bases 1 to 495)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   4  (bases 1 to 495)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   5  (bases 1 to 495)
  AUTHORS   Xiao,H.S., Huang,Q.H., Zhang,F.X., Bao,L., Lu,Y.J., Guo,C.,
            Yang,L., Huang,W.J., Fu,G., Xu,S.H., Cheng,X.P., Yan,Q., Zhu,Z.D.,
            Zhang,X., Chen,Z., Han,Z.G. and Zhang,X.
  TITLE     Identification of gene expression profile of dorsal root ganglion
            in the rat peripheral axotomy model of neuropathic pain
  JOURNAL   Proc Natl Acad Sci U S A 99 (12), 8360-8365 (2002)
   PUBMED   12060780
REFERENCE   6  (bases 1 to 495)
  AUTHORS   Schagger,H., Noack,H., Halangk,W., Brandt,U. and von Jagow,G.
  TITLE     Cytochrome-c oxidase in developing rat heart. Enzymic properties
            and amino-terminal sequences suggest identity of the fetal heart
            and the adult liver isoform
  JOURNAL   Eur J Biochem 230 (1), 235-241 (1995)
   PUBMED   7601105
REFERENCE   7  (bases 1 to 495)
  AUTHORS   Enders,C., Schlerf,A., Mell,O., Grossman,L.I. and Kadenbach,B.
  TITLE     Nucleotide sequence of cDNA encoding subunit VIIa of rat liver
            cytochrome c oxidase
  JOURNAL   Nucleic Acids Res 18 (23), 7143 (1990)
   PUBMED   2175887
REFERENCE   8  (bases 1 to 495)
  AUTHORS   Kennaway,N.G., Carrero-Valenzuela,R.D., Ewart,G., Balan,V.K.,
            Lightowlers,R., Zhang,Y.Z., Powell,B.R., Capaldi,R.A. and
            Buist,N.R.
  TITLE     Isoforms of mammalian cytochrome c oxidase: correlation with human
            cytochrome c oxidase deficiency
  JOURNAL   Pediatr Res 28 (5), 529-535 (1990)
   PUBMED   2175025
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BG668415.1 and AW521400.1.
            
            On Nov 15, 2007 this sequence version replaced NM_022503.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ229035.1, FQ230547.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-335               BG668415.1         8-342
            336-495             AW521400.1         1-160               c
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..495
                     /gene="Cox7a2"
                     /gene_synonym="Cox7a3"
                     /note="cytochrome c oxidase subunit 7A2"
                     /db_xref="GeneID:29507"
                     /db_xref="RGD:68365"
     exon            1..100
                     /gene="Cox7a2"
                     /gene_synonym="Cox7a3"
                     /inference="alignment:Splign:2.1.0"
     CDS             83..334
                     /gene="Cox7a2"
                     /gene_synonym="Cox7a3"
                     /EC_number="7.1.1.9"
                     /note="cytochrome c oxidase subunit VIIa 3; cytochrome c
                     oxidase polypeptide 7A2, mitochondrial; cytochrome c
                     oxidase subunit 7A2, mitochondrial; cytochrome c oxidase
                     subunit VIIa-L; cytochrome c oxidase polypeptide
                     VIIa-liver/heart; cytochrome c oxidase subunit
                     VIIa-liver/heart; cytochrome c oxidase, subunit VIIa 2;
                     cytochrome c oxidase, subunit 7a 3; cytochrome c oxidase
                     subunit VIIa polypeptide 2"
                     /codon_start=1
                     /product="cytochrome c oxidase subunit 7A2, mitochondrial
                     precursor"
                     /protein_id="NP_071948.1"
                     /db_xref="GeneID:29507"
                     /db_xref="RGD:68365"
                     /translation="MLRNVLALRQIAQRTISTTSRRHFENKVPEKQKLFQEDNGMPVH
                     LKGGTSDALLYRATMLLTVGGTAYAIYMLAMAAFPKKQN"
     exon            101..190
                     /gene="Cox7a2"
                     /gene_synonym="Cox7a3"
                     /inference="alignment:Splign:2.1.0"
     exon            191..275
                     /gene="Cox7a2"
                     /gene_synonym="Cox7a3"
                     /inference="alignment:Splign:2.1.0"
     exon            276..479
                     /gene="Cox7a2"
                     /gene_synonym="Cox7a3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagggagtt ccgtttccgg tctggtggtt ttcgattttt ggcgttcagt agtcgcggtt
       61 ggtgggtaac aactgagcta agatgctgcg gaatgtgctg gcccttcgtc agattgccca
      121 gaggaccatc agcaccactt cacgaaggca ttttgaaaac aaagttccag agaagcaaaa
      181 gctgtttcag gaggataatg ggatgccagt tcatctgaaa ggcgggacat ctgatgccct
      241 cctttacaga gccacaatgc ttctgacagt tggtggaaca gcgtatgcca tctatatgtt
      301 agctatggct gcattcccca agaagcagaa ctgacgtcgt catcccagtc tccacatggt
      361 tcagtttcat tcactgcgcg atggaccagg aacctgatga ataactgaac tcttctatgg
      421 ggatcaatat ttattgatgt gtattaactg ccaccaataa agcagtcctt aaccatttaa
      481 aaaaaaaaaa aaaaa
//
