LOCUS       NM_019360                465 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cytochrome c oxidase subunit 6C (Cox6c), mRNA.
ACCESSION   NM_019360
VERSION     NM_019360.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Zong,S., Wu,M., Gu,J., Liu,T., Guo,R. and Yang,M.
  TITLE     Structure of the intact 14-subunit human cytochrome c oxidase
  JOURNAL   Cell Res 28 (10), 1026-1034 (2018)
   PUBMED   30030519
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   3  (bases 1 to 465)
  AUTHORS   Farkas,R.H., Qian,J., Goldberg,J.L., Quigley,H.A. and Zack,D.J.
  TITLE     Gene expression profiling of purified rat retinal ganglion cells
  JOURNAL   Invest Ophthalmol Vis Sci 45 (8), 2503-2513 (2004)
   PUBMED   15277470
REFERENCE   4  (bases 1 to 465)
  AUTHORS   Sheehan,T.E., Kumar,P.A. and Hood,D.A.
  TITLE     Tissue-specific regulation of cytochrome c oxidase subunit
            expression by thyroid hormone
  JOURNAL   Am J Physiol Endocrinol Metab 286 (6), E968-E974 (2004)
   PUBMED   14970006
REFERENCE   5  (bases 1 to 465)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   6  (bases 1 to 465)
  AUTHORS   Crosignani,P.
  TITLE     [Malignant breast tumors in the population of the province of
            Varese from 01/01/76 to 12/31/87]
  JOURNAL   Pathologica 84 (1094), 1-9 (1992)
   PUBMED   1300526
REFERENCE   7  (bases 1 to 465)
  AUTHORS   Suske,G., Enders,C., Schlerf,A. and Kadenbach,B.
  TITLE     Organization and nucleotide sequence of two chromosomal genes for
            rat cytochrome c oxidase subunit VIc: a structural and a processed
            gene
  JOURNAL   DNA 7 (3), 163-171 (1988)
   PUBMED   2836143
REFERENCE   8  (bases 1 to 465)
  AUTHORS   Cao,X.N., Hengst,L., Schlerf,A., Droste,M., Mengel,T. and
            Kadenbach,B.
  TITLE     Complexity of nucleus-encoded genes of mammalian cytochrome c
            oxidase
  JOURNAL   Ann N Y Acad Sci 550, 337-347 (1988)
   PUBMED   2854406
REFERENCE   9  (bases 1 to 465)
  AUTHORS   Suske,G., Mengel,T., Cordingley,M. and Kadenbach,B.
  TITLE     Molecular cloning and further characterization of cDNAs for rat
            nuclear-encoded cytochrome c oxidase subunits VIc and VIII
  JOURNAL   Eur J Biochem 168 (1), 233-237 (1987)
   PUBMED   2822403
REFERENCE   10 (bases 1 to 465)
  AUTHORS   Parimoo,S., Seelan,R.S., Desai,S., Buso,G. and Padmanaban,G.
  TITLE     Construction of a cDNA clone for a nuclear-coded subunit of
            cytochrome c oxidase from rat liver
  JOURNAL   Biochem Biophys Res Commun 118 (3), 902-909 (1984)
   PUBMED   6200111
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF976717.1, BC058480.1 and AI716762.1.
            
            On Nov 15, 2007 this sequence version replaced NM_019360.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CF976718.1, FQ217805.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                CF976717.1         5-31
            28-441              BC058480.1         4-417
            442-465             AI716762.1         1-24                c
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q22"
     gene            1..465
                     /gene="Cox6c"
                     /gene_synonym="COVIc; COX-VIc; Cox6c2"
                     /note="cytochrome c oxidase subunit 6C"
                     /db_xref="GeneID:54322"
                     /db_xref="RGD:620616"
     exon            1..71
                     /gene="Cox6c"
                     /gene_synonym="COVIc; COX-VIc; Cox6c2"
                     /inference="alignment:Splign:2.1.0"
     exon            72..201
                     /gene="Cox6c"
                     /gene_synonym="COVIc; COX-VIc; Cox6c2"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..315
                     /gene="Cox6c"
                     /gene_synonym="COVIc; COX-VIc; Cox6c2"
                     /note="cytochrome c oxidase polypeptide VIc-2; cytochrome
                     oxidase subunit VIc; cytochrome c oxidase, subunit VIc"
                     /codon_start=1
                     /product="cytochrome c oxidase subunit 6C-2"
                     /protein_id="NP_062233.2"
                     /db_xref="GeneID:54322"
                     /db_xref="RGD:620616"
                     /translation="MSSGALLPKPQMRGLLAKRLRVHIVGAFVVALGVAAAYKFGVAE
                     PRKKAYADFYRNYDSMKDFEEMRQAGVFQSAK"
     exon            202..330
                     /gene="Cox6c"
                     /gene_synonym="COVIc; COX-VIc; Cox6c2"
                     /inference="alignment:Splign:2.1.0"
     exon            331..450
                     /gene="Cox6c"
                     /gene_synonym="COVIc; COX-VIc; Cox6c2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gactcctgcg catgcgtgct gctagaaggc tctccgtttc tccgagaacc gggaaggacg
       61 ttggtataga ggacattggc taccatgagt tccggtgctc tgttgccgaa accacagatg
      121 cgtggtcttc tggccaagcg tctgcgggtt catattgttg gcgcattcgt tgtggcccta
      181 ggagttgctg ctgcctataa gtttggcgtg gctgaaccaa gaaagaaggc ttatgcagat
      241 ttctacagga attatgactc catgaaagat tttgaagaga tgaggcaggc tggtgtcttt
      301 cagagtgcga agtgatttca gaatgcaaag aattctttgg attgtgctcc atagaagttc
      361 actgctgacc tgtgttcctg aactatgaaa cgtgaatatg tgggctaagg agtagtttct
      421 ctcaataaac attaattata tggacagtaa aaaaaaaaaa aaaaa
//
