LOCUS       NM_001105976            1028 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus cytochrome c oxidase assembly factor COX20
            (Cox20), mRNA.
ACCESSION   NM_001105976 XM_001059804 XM_213949
VERSION     NM_001105976.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1028)
  AUTHORS   Bourens M, Boulet A, Leary SC and Barrientos A.
  TITLE     Human COX20 cooperates with SCO1 and SCO2 to mature COX2 and
            promote the assembly of cytochrome c oxidase
  JOURNAL   Hum Mol Genet 23 (11), 2901-2913 (2014)
   PUBMED   24403053
REFERENCE   2  (bases 1 to 1028)
  AUTHORS   Szklarczyk R, Wanschers BF, Nijtmans LG, Rodenburg RJ, Zschocke J,
            Dikow N, van den Brand MA, Hendriks-Franssen MG, Gilissen C,
            Veltman JA, Nooteboom M, Koopman WJ, Willems PH, Smeitink JA,
            Huynen MA and van den Heuvel LP.
  TITLE     A mutation in the FAM36A gene, the human ortholog of COX20, impairs
            cytochrome c oxidase assembly and is associated with ataxia and
            muscle hypotonia
  JOURNAL   Hum Mol Genet 22 (4), 656-667 (2013)
   PUBMED   23125284
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473985.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_213949.3, XM_001059804.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ215236.1, FQ229252.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1028
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q25"
     gene            1..1028
                     /gene="Cox20"
                     /gene_synonym="Fam36a; RGD1309105"
                     /note="cytochrome c oxidase assembly factor COX20"
                     /db_xref="GeneID:289278"
                     /db_xref="RGD:1309105"
     exon            1..288
                     /gene="Cox20"
                     /gene_synonym="Fam36a; RGD1309105"
                     /inference="alignment:Splign:2.1.0"
     CDS             250..603
                     /gene="Cox20"
                     /gene_synonym="Fam36a; RGD1309105"
                     /note="family with sequence similarity 36, member A; COX20
                     Cox2 chaperone homolog; COX20 cytochrome C oxidase
                     assembly factor"
                     /codon_start=1
                     /product="cytochrome c oxidase assembly factor COX20"
                     /protein_id="NP_001099446.1"
                     /db_xref="GeneID:289278"
                     /db_xref="RGD:1309105"
                     /translation="MAAASEPHEPEKKPFKLLGILDVENTPCARESILYGSLGSIVTG
                     LGHFLVTSRIRRSCDVGVGGFILVTLGCWFHCRYNFAKQRIQERIAREGIKNKILYES
                     THLDPERKTKSSNSS"
     exon            289..403
                     /gene="Cox20"
                     /gene_synonym="Fam36a; RGD1309105"
                     /inference="alignment:Splign:2.1.0"
     exon            404..467
                     /gene="Cox20"
                     /gene_synonym="Fam36a; RGD1309105"
                     /inference="alignment:Splign:2.1.0"
     exon            468..1028
                     /gene="Cox20"
                     /gene_synonym="Fam36a; RGD1309105"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgcctgcga gacaggaacc ggtggagctt ctctaggttg tctcctcttg tgttccattc
       61 ctgatggtct gttgcggggt tggaaaaaca gtgtggttgg ttccaaggaa caaaagaggg
      121 ggccacggcg ggcttcggga cggccccagg atcgctccct aagatggccg ccgccgtgag
      181 ggagggtggg cggagcccgt actgcttccg tcgcgggcct gggcggggcg gtagcgacta
      241 cttgcaccca tggctgccgc ctcggagccc cacgagccgg agaaaaagcc cttcaagctc
      301 ctaggtattt tagatgttga gaacactcca tgcgctcgag aatctatact gtatggctca
      361 ctaggatcta ttgtgactgg acttggacat ttcttggtga ccagcagaat tagaagatcc
      421 tgtgatgttg gagtaggagg atttatcctg gtgactttag gatgctggtt ccactgtagg
      481 tataattttg ctaagcagag gatccaggaa agaattgcca gagaaggaat aaaaaacaag
      541 attttatatg aaagcaccca ccttgatcct gaaagaaaaa cgaagagcag taacagcagc
      601 tgagcgactt catcagcttt aaacccacaa ctatgcttcc ttgtgaatca accataaatt
      661 aaactcaagt gtgtcaactg tattgttacc tacatgaaat ccttttgttt actgccagta
      721 agttatgtct gtcatgtatc acagaactgc catgtcaaac acatgggagt cagggtcctg
      781 ctcttcctaa ggtgtcagat tcattatctg ttcacaaagt acatcagatt gaaggagaaa
      841 tcacacctga gcagggatat gtatctatta ctggcctagg actttgtcta ttgaagcttc
      901 aacaggaaag actgttaacg atggacacta agaagccttg catctggtag ccctactatt
      961 tcatccttga taaagttgag tttgtagtag gtcaatcaag tattttaaca agctgtggac
     1021 agtgcact
//
