LOCUS       NM_001107126            2648 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus cytochrome c oxidase assembly factor COX19
            (Cox19), mRNA.
ACCESSION   NM_001107126 XM_001074417 XM_221972
VERSION     NM_001107126.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2648)
  AUTHORS   Fischer,M., Horn,S., Belkacemi,A., Kojer,K., Petrungaro,C.,
            Habich,M., Ali,M., Kuttner,V., Bien,M., Kauff,F., Dengjel,J.,
            Herrmann,J.M. and Riemer,J.
  TITLE     Protein import and oxidative folding in the mitochondrial
            intermembrane space of intact mammalian cells
  JOURNAL   Mol Biol Cell 24 (14), 2160-2170 (2013)
   PUBMED   23676665
REFERENCE   2  (bases 1 to 2648)
  AUTHORS   Leary,S.C., Cobine,P.A., Nishimura,T., Verdijk,R.M., de Krijger,R.,
            de Coo,R., Tarnopolsky,M.A., Winge,D.R. and Shoubridge,E.A.
  TITLE     COX19 mediates the transduction of a mitochondrial redox signal
            from SCO1 that regulates ATP7A-mediated cellular copper efflux
  JOURNAL   Mol Biol Cell 24 (6), 683-691 (2013)
   PUBMED   23345593
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Mar 12, 2011 this sequence version replaced NM_001107126.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.551897.1, CR754322.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-110               JAXUCZ010000012.1  20417389-20417498
            111-222             JAXUCZ010000012.1  20420009-20420120
            223-2648            JAXUCZ010000012.1  20424443-20426868
FEATURES             Location/Qualifiers
     source          1..2648
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q11"
     gene            1..2648
                     /gene="Cox19"
                     /gene_synonym="RGD1305631"
                     /note="cytochrome c oxidase assembly factor COX19"
                     /db_xref="GeneID:304330"
                     /db_xref="RGD:1305631"
     exon            1..110
                     /gene="Cox19"
                     /gene_synonym="RGD1305631"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..307
                     /gene="Cox19"
                     /gene_synonym="RGD1305631"
                     /note="cytochrome c oxidase assembly homolog 19;
                     cytochrome c oxidase assembly protein 19; COX19 cytochrome
                     c oxidase assembly factor"
                     /codon_start=1
                     /product="COX19 cytochrome c oxidase assembly homolog"
                     /protein_id="NP_001100596.1"
                     /db_xref="GeneID:304330"
                     /db_xref="RGD:1305631"
                     /translation="MSTAMNFGTKSFQPRPPDKGSFPLDHFGECKSFKEKFMKCLRDK
                     NYENALCRNESKEYLMCRMQRQLMAPEPLEKLGFRDIMEEKPEAKDKC"
     exon            111..222
                     /gene="Cox19"
                     /gene_synonym="RGD1305631"
                     /inference="alignment:Splign:2.1.0"
     exon            223..2648
                     /gene="Cox19"
                     /gene_synonym="RGD1305631"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccgctctcc gctcttgatt tcgccgtgat gtcgaccgca atgaacttcg ggaccaaaag
       61 cttccagccg cggcccccag acaaaggcag cttcccgcta gaccacttcg gtgagtgtaa
      121 aagctttaag gaaaaattca tgaagtgtct ccgcgacaag aactatgaaa atgctctgtg
      181 cagaaatgaa tctaaagagt atttaatgtg caggatgcaa aggcagctga tggcaccaga
      241 accactagag aaactcggct ttagagacat aatggaggag aaaccggagg caaaggacaa
      301 atgttgagaa tcactgggct gtgtccccct acctggagca gagctgagcc cttctgccca
      361 ccgtggagag agctgagcca tcctgtgctg cccagaggag gggctctccg tgttgacttt
      421 ggctcatccc tgcagcatag accagactgc ttcctctact gaccacactt ctgcttcaga
      481 gagtggtttt ctcctgtctg tgtgtgtcac aggatctgct cagggctgaa cactgatgtg
      541 atatgatatc ccacctagtg tggccgtcac accagaggcc ctggacagca ttccacagtg
      601 actcaacctg agtcctcaca ccggaacctg tcagcgaaac caagcgacag caaaatgtct
      661 gccttttgtg ctcacagacg cacatcatct tgcttcccct tctcttgtgt tctttgcttt
      721 gaacaaaact ggaatacaaa gtaggaagtg agaaatagtt tggcttttga catagttgac
      781 ctcctgtttt aagtgttttg agacagggtc tcagaccgcc cgtgtaccca aggatgacct
      841 cgaactcttg atccttctgc ctccatgtct agggtattgg ggcatggaac ccagggctcc
      901 ctgcacgata ggcaagcact ctctcagctg aaccgtgtct ccagctaggg aagcactgta
      961 tctcagtgtg tttgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtc
     1021 agaggacaac ttagaggagt ccgatctctc cttgcccaag tgagtgtctc agggattgaa
     1081 ctcgggtcac caggcttggt agatgtctca gctcaacttc cattccccca gtctaggagc
     1141 agatggcttc atgacgcggg ttgggttatt ttctggtcgt ctcaagctgt ctgtaaacct
     1201 ggcttttcct ttcagtggcc caccgcatgc ctccacaggg cgggtcagcc acgcacagag
     1261 gctgggctag gatctatccc ttttccactg ttgcaccgtg ttgcagtaac attgcactta
     1321 cgtgtctgtg ggtgctgacg ctaaccctgt actgtcagca ctgagcagcg ctgagctgtg
     1381 gcttagccca ggctatcctc agagttccct gtgggttgtt taaacaccca ggcgccttca
     1441 tcctgaggca ggtgatggga aggggggagc agctgggttc ggggcttctg ctgtgtgcag
     1501 ggatccaaag acaccagcag aacgccagtg ccaggtgttg tcaggctcca gtgcctcaga
     1561 tgtgtcctcc tagagctgtt ggagaagggc tgtccccctg cttgtcctgg ctcctgtctg
     1621 actggtgaag gacaccatgg gtgggatggg gcaggtattg tggcgcacaa ctttagcacc
     1681 caagaggcag aggcaggcag atccttgagt ttgaggccag ttttgtctac agagtgagtt
     1741 gtaggagagc caggacgaca tagagagaga gagaccctct ggggttgggg cagagggtgg
     1801 gagagagaaa cggggatggg aagaggactt cgtatattca tatccctgtt ggtcttaggc
     1861 tctggcactg cgaggcctgc agggtctgct gatctcctgg gggcagcttc cccttcccca
     1921 ggagatgtga gcgcctgtga gcctggtttg ctgttacaca gaaagacctc ttcctggttg
     1981 gacccatagt cctgcacacc ggggtctgct tgttcacaca ctcgctcagc ccggccacac
     2041 agagcggggc agcaccaggt ccacatgtca cgtttgagcc ttggttttta tcaccaacat
     2101 tagtgtcacc gcagtactgt ggtgttggag cagccaagct cacttgttag gactcgaggt
     2161 gtgtggcgag cactccagtg actgggccat ctcctcggcc attttgttgt gtctgtttat
     2221 caagagaggg cccactctgt agccaaggct ggccttgaac tctgtttcca cctcccaagt
     2281 cctgccatct tccaagcctt tgatgtctgt tatcagcaag tgacaaaatg aacatatgtc
     2341 acagtcaagt acggctgagt tttccaacac atcacggcgg ctccatccac gagtgcccca
     2401 cttgtccacc catctccagc gagatgcagg aacacagcat agcaacactg atggctttgg
     2461 ggctggagtt ggaggatgct cggttccctc ctgggatgtt cacggttata tcttataaca
     2521 agtgtgcatc atttttatag aaactataaa atccttactt gaagggaact caccgtgttg
     2581 agtagtgttt ccatatcctc tgtaaattac aggccagttg taatttctaa tcccctgtgg
     2641 ataccaaa
//
