LOCUS       NM_001163153             770 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus cytochrome c oxidase assembly factor COX16
            (Cox16), mRNA.
ACCESSION   NM_001163153
VERSION     NM_001163153.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 770)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 770)
  AUTHORS   Cerqua,C., Morbidoni,V., Desbats,M.A., Doimo,M., Frasson,C.,
            Sacconi,S., Baldoin,M.C., Sartori,G., Basso,G., Salviati,L. and
            Trevisson,E.
  TITLE     COX16 is required for assembly of cytochrome c oxidase in human
            cells and is involved in copper delivery to COX2
  JOURNAL   Biochim Biophys Acta Bioenerg 1859 (4), 244-252 (2018)
   PUBMED   29355485
REFERENCE   3  (bases 1 to 770)
  AUTHORS   Aich,A., Wang,C., Chowdhury,A., Ronsor,C., Pacheu-Grau,D.,
            Richter-Dennerlein,R., Dennerlein,S. and Rehling,P.
  TITLE     COX16 promotes COX2 metallation and assembly during respiratory
            complex IV biogenesis
  JOURNAL   Elife 7, e32572 (2018)
   PUBMED   29381136
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CO565953.1, CK471447.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840111,
                                           SAMN12840129 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-217               JAXUCZ010000006.1  106912268-106912484 c
            218-289             JAXUCZ010000006.1  106907995-106908066 c
            290-352             JAXUCZ010000006.1  106902622-106902684 c
            353-770             JAXUCZ010000006.1  106899494-106899911 c
FEATURES             Location/Qualifiers
     source          1..770
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q24"
     gene            1..770
                     /gene="Cox16"
                     /note="cytochrome c oxidase assembly factor COX16"
                     /db_xref="GeneID:100302447"
                     /db_xref="RGD:2311610"
     exon            1..217
                     /gene="Cox16"
                     /inference="alignment:Splign:2.1.0"
     CDS             149..469
                     /gene="Cox16"
                     /note="cytochrome c oxidase assembly protein 16; COX16,
                     cytochrome c oxidase assembly homolog"
                     /codon_start=1
                     /product="COX16 cytochrome c oxidase assembly homolog"
                     /protein_id="NP_001156625.1"
                     /db_xref="GeneID:100302447"
                     /db_xref="RGD:2311610"
                     /translation="MVAPAVLRALRKNKTLRYGVPMLLLVVGGSFGLREFSQIRYDAV
                     TIKIDPELEKKLKVNKITLESEYEKIKDSTFENWKNIRGPRPWEDPQLLQGRNPETLK
                     PKTT"
     exon            218..289
                     /gene="Cox16"
                     /inference="alignment:Splign:2.1.0"
     exon            290..352
                     /gene="Cox16"
                     /inference="alignment:Splign:2.1.0"
     exon            353..770
                     /gene="Cox16"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actaatggat ttagtttcaa tcatggaggt ctgtcaggtg aggacctagc tcccaaagcc
       61 agcgctgagt ctacaacttc tcctaagagg tgttccggcc ggcgttgggg tctctgcgga
      121 ggcggctaaa tcggccgcag tttctgccat ggttgcgccc gctgtgttgc gcgctctgcg
      181 taagaacaag acccttcgct atggagttcc catgttgttg ctggttgttg gtggttcttt
      241 tggtcttcgc gaattttcac aaatccgata tgatgctgtg acaattaaga ttgatcctga
      301 attggagaaa aaattgaaag tgaataaaat aactttagag tcagagtatg agaaaataaa
      361 ggactccact tttgaaaact ggaagaatat tcgtggtccg aggccttggg aagatcctca
      421 actcctccaa ggacgaaacc cagaaactct taagcctaag acaacctgac tgtgctcagg
      481 ttttgtctcg ttctggtttt tcaatgaagt agtctcatct ccatctgtag gaagaagagt
      541 ccagacctgt ggaaacctgg atgtgaataa tatgatggca gaaactttta ttaaaaagtc
      601 acatataagt ctgtatgctt ttcaatcagt ctacttgcaa ataaaaatat gttgaacaca
      661 cacacacaca cacacacaca ccactacaaa tctataaaaa atgtgaccct tgcttcccca
      721 acatgctgtg ctgtgcattc tactttccta ttacccactc atattctttt
//
