LOCUS       NM_001109575            2506 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cytochrome c oxidase copper chaperone COX11
            (Cox11), mRNA.
ACCESSION   NM_001109575 XM_001074020
VERSION     NM_001109575.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2506)
  AUTHORS   Aslanukov,A., Bhowmick,R., Guruju,M., Oswald,J., Raz,D., Bush,R.A.,
            Sieving,P.A., Lu,X., Bock,C.B. and Ferreira,P.A.
  TITLE     RanBP2 modulates Cox11 and hexokinase I activities and
            haploinsufficiency of RanBP2 causes deficits in glucose metabolism
  JOURNAL   PLoS Genet 2 (10), e177 (2006)
   PUBMED   17069463
REFERENCE   2  (bases 1 to 2506)
  AUTHORS   Guo,D., Ling,J., Wang,M.H., She,J.X., Gu,J. and Wang,C.Y.
  TITLE     Physical interaction and functional coupling between ACDP4 and the
            intracellular ion chaperone COX11, an implication of the role of
            ACDP4 in essential metal ion transport and homeostasis
  JOURNAL   Mol Pain 1, 15 (2005)
   PUBMED   15840172
  REMARK    GeneRIF: ACDP4 specifically interacts with COX11, an intracellular
            metal ion chaperone.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2506)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   4  (bases 1 to 2506)
  AUTHORS   Leary,S.C., Kaufman,B.A., Pellecchia,G., Guercin,G.H., Mattman,A.,
            Jaksch,M. and Shoubridge,E.A.
  TITLE     Human SCO1 and SCO2 have independent, cooperative functions in
            copper delivery to cytochrome c oxidase
  JOURNAL   Hum Mol Genet 13 (17), 1839-1848 (2004)
   PUBMED   15229189
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On Oct 4, 2007 this sequence version replaced XM_001074020.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2506
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..2506
                     /gene="Cox11"
                     /note="cytochrome c oxidase copper chaperone COX11"
                     /db_xref="GeneID:103693419"
                     /db_xref="RGD:9174727"
     exon            1..383
                     /gene="Cox11"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..848
                     /gene="Cox11"
                     /note="cytochrome c oxidase assembly protein COX11,
                     mitochondrial; cytochrome c oxidase assembly homolog 11;
                     cytochrome c oxidase assembly protein 11; COX11 cytochrome
                     c oxidase copper chaperone"
                     /codon_start=1
                     /product="cytochrome c oxidase copper chaperone COX11"
                     /protein_id="NP_001103045.1"
                     /db_xref="GeneID:103693419"
                     /db_xref="RGD:9174727"
                     /translation="MGGLWCPGWRFITLCGRGWSQPRWSGRTVVNAERALRPGWNGVG
                     GAEQGLRRLGTWKRPSGARGPVAQPPRRPKSSNPFQRAQEDEWRRRNKTVLTYVAAAA
                     VGMLGASYAAVPLYRLYCQTTGLGGSAVAGHASDQIENMVPVKDRIIKVTFNADVHAS
                     LQWNFRPQQTEIYVVPGETALAFYKAKNPTDKPVIGISTYNVVPFEAGQYFNKIQCFC
                     FEEQRLNPQEEVDMPVFFYIDPEFAEDPRMVNVDLITLSYTFFEAKEGHKLAVPGYN"
     exon            384..539
                     /gene="Cox11"
                     /inference="alignment:Splign:2.1.0"
     exon            540..665
                     /gene="Cox11"
                     /inference="alignment:Splign:2.1.0"
     exon            666..2506
                     /gene="Cox11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgttcttt ccggggggtt atgggagggc tctggtgtcc gggatggagg ttcatcactt
       61 tgtgtggccg gggctggagc cagccccggt ggtcgggccg gacggtggtg aacgcagagc
      121 gggctcttag gccgggatgg aatggggtcg gaggcgcgga gcagggactg agacgcctcg
      181 ggacatggaa gcgcccgagc ggggcccggg gtcccgtcgc gcagccgcca cggcggccga
      241 agagcagcaa ccctttccag cgggcgcagg aagacgagtg gcggcggcgg aacaagacgg
      301 tgctcacgta cgtggccgcg gccgccgtgg gcatgctggg ggcctcgtac gccgcggtgc
      361 ccctctatcg gctctactgc cagactactg gacttggagg atcagcagtg gctgggcatg
      421 cctcagacca gattgaaaac atggtgcctg ttaaggaccg gatcattaag gtcaccttca
      481 atgctgacgt tcacgccagt ctccagtgga acttcagacc tcagcaaaca gagatctatg
      541 tggtaccagg agagactgca ctggcatttt ataaagctaa gaatcctact gacaaaccag
      601 taattggaat ttctacatat aatgttgtac cgtttgaagc cggacaatat ttcaataaaa
      661 tacagtgctt ctgttttgaa gaacaaaggc ttaatccaca agaagaagta gatatgccag
      721 tgtttttcta cattgatcct gaatttgcag aagatccaag aatggtgaat gtcgacctca
      781 tcactctttc ttacactttt tttgaagcga aggaagggca caagttggca gttccaggct
      841 acaattgaag tagctcccaa gacctgcatc agatttgcga tttttggaaa atcatgtatt
      901 gtgctttctc agaagagaat attctacagt aatgtatttt gaaaccttgt attttaaatg
      961 gttttgcctt tctttctttg caattcattt atcccactta agattgagaa aagaagttca
     1021 aaactcagtc tgtggtgaga aaatgctgct atcctgtgat ggtgcttaag ggcaggaagt
     1081 gaacactgct gttttaagta atagaatatg aacattcttt atatcccaag cctggagagt
     1141 atatgactgc ccaatgtacc acaagtgtga cgattgaaaa ctgcatcatg ggccaggcag
     1201 gtgaatcagt gggttgaagt gtttgccaca caggactgac aacttgaatt ctggttgctg
     1261 gaaccagcct gaaaagagtg agtgtaatag ctcacctctg tggtcccaga gttctcacag
     1321 tgagtaggag cttaagccag gaggatcgtt ttgcctgtat atgcatgcgc tggctgccca
     1381 cacagatgta aattgcttga atagcccttc atacctgtaa taatgtctct gaaaacctca
     1441 agaaagaaac tgtgtgcaac tctttgagtt cataacatgc aggctgctct tccttcagta
     1501 taaactgaca ccatttaaaa atgtatttat tttctcagta tgtatgcaag atgaatgcta
     1561 cccatgctgc agcagacaat gtagtgggca agctgtggga gagcattttc tcttactatg
     1621 gggtctctga gtatgacagg gtagtgaatg ccttcagcta ctgagctttc tttggctgaa
     1681 tcaacagtta aaagctcagt gttagaggag tcacttggtc ccaagtttgc atttttagtt
     1741 caagcgtgtg gcttttctgt taggcttgag tgctgtttta ttcagagtac tgaaaataga
     1801 tgataacatg gaaatgatgg tatcatgatc taacagaatt acacctgctg gctaagctag
     1861 catttaccac cataattcca agttcattaa cattatcatt ggaagggtga aattgtgaag
     1921 acttactggc ataaaagctc attaaactag aagacagaac aagaacaaca caactctgac
     1981 aaattaatag taatttaatt ttacgtgaat gatgcattgc cctgttttcc agtaatcttt
     2041 gtttcaaatc agaatgtgaa ttataataaa aggcaagaat gtttaacatt ataaagaact
     2101 aactacacct aaaggccgcc tgatgcagtg gcctcctcag gcacttgaaa tacaattaaa
     2161 gtcatcaagt ctttcaagcc attctaaacc aaaatgttat ttataaacaa gtacaaactg
     2221 aactctacat tcagattcag ttcaataaag gcactcattt tcttccttcc cccatctgtt
     2281 tacaatgttt tctaataggg tcttaaagta accctgtcat aggtctgtca tgatttgcac
     2341 tgggtgcaag cctgcacaac ataagagtct acagtttaac caagtggtct agtactaggc
     2401 agttttcctt ctgctgaagt tgttacaacc agattttcct gaaatcttga gccattgtga
     2461 ggaacagcag tgttgcccaa aaagtgttag cttttatgtt gaagtt
//
