LOCUS       NM_139115               2444 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus coronin 6 (Coro6), mRNA.
ACCESSION   NM_139115
VERSION     NM_139115.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2444)
  AUTHORS   Chen,Y., Ip,F.C., Shi,L., Zhang,Z., Tang,H., Ng,Y.P., Ye,W.C.,
            Fu,A.K. and Ip,N.Y.
  TITLE     Coronin 6 regulates acetylcholine receptor clustering through
            modulating receptor anchorage to actin cytoskeleton
  JOURNAL   J Neurosci 34 (7), 2413-2421 (2014)
   PUBMED   24523531
  REMARK    GeneRIF: these findings demonstrate that Coronin 6 is a critical
            regulator of AChR clustering at the postsynaptic region of the
            neuromuscular junction
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC098656.1.
            
            On Jun 10, 2007 this sequence version replaced NM_139115.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098656.1, AF140359.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760384, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2444
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..2444
                     /gene="Coro6"
                     /note="coronin 6"
                     /db_xref="GeneID:245982"
                     /db_xref="RGD:708560"
     exon            1..222
                     /gene="Coro6"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..1443
                     /gene="Coro6"
                     /note="clipin E; coronin relative protein; coronin, actin
                     binding protein 6"
                     /codon_start=1
                     /product="coronin-6"
                     /protein_id="NP_620815.2"
                     /db_xref="GeneID:245982"
                     /db_xref="RGD:708560"
                     /translation="MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNP
                     KFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTGPVLDIDWCPHNDNVIASASD
                     DTTVMVWQIPDYTPVRNITEPVITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWN
                     VGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKSQVVAERFAAHE
                     GMRPMRAVFTRLGHIFTTGFTRMSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDP
                     DSSIVYLCGKGDSSIRYFEITDEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIA
                     RFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLK
                     EGYVPPKHREFRVTKRNILDVRPPASPRRSQSASEAPLSQQHTLETLLEEMKALRERV
                     QAQEERITALENMLCELVDGTD"
     exon            223..345
                     /gene="Coro6"
                     /inference="alignment:Splign:2.1.0"
     exon            346..475
                     /gene="Coro6"
                     /inference="alignment:Splign:2.1.0"
     exon            476..657
                     /gene="Coro6"
                     /inference="alignment:Splign:2.1.0"
     exon            658..777
                     /gene="Coro6"
                     /inference="alignment:Splign:2.1.0"
     exon            778..882
                     /gene="Coro6"
                     /inference="alignment:Splign:2.1.0"
     exon            883..1028
                     /gene="Coro6"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1086
                     /gene="Coro6"
                     /inference="alignment:Splign:2.1.0"
     exon            1087..1317
                     /gene="Coro6"
                     /inference="alignment:Splign:2.1.0"
     exon            1318..2418
                     /gene="Coro6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctctgata tctttgcccc agccatgagc cgtcgtgtgg ttcggcaaag caagttccgc
       61 catgtgtttg gtcaggcagc aaaggccgac caggcctatg aggacatccg ggtatccaag
      121 gtcacatggg acagcgcctt ctgtgccgtc aaccccaaat ttctagccat tattgtggag
      181 gctggaggtg gaggcgcctt cattgtcctg cctctggcca agacaggacg agtggataag
      241 aactacccac tggtcactgg acacactggc cctgtgctgg acattgactg gtgcccacac
      301 aatgacaacg tcatcgccag tgcctcagat gacaccactg tcatggtgtg gcagattcca
      361 gactacaccc cagtgcgaaa catcacagaa cctgtcatca cactcgaggg ccactccaag
      421 cgtgtgggca tcctgtcttg gcatcctact gccaggaatg tcctgctcag tgcaggtggt
      481 gataatgtga tcatcatctg gaatgtgggc actggggagg tactgctgag cctagacgac
      541 atacaccctg acgtcatcca cagcgtgtgt tggaacagca atggtagcct gctagccacc
      601 acttgcaagg acaagacctt gcgtatcatt gacccccgga agagtcaagt ggttgcggag
      661 aggtttgcag cccacgaggg gatgaggccc atgcgggctg tcttcacacg gctgggtcat
      721 atcttcacca cgggattcac ccgcatgagc cagcgagagc taggcctgtg ggacccgaac
      781 aacttcgaag aaccagtggc cctgcaggaa atggacacaa gcaacggagt gttactacca
      841 ttctacgatc ctgactccag catcgtctac ttgtgtggca agggtgacag tagcattcgg
      901 tactttgaaa ttacggacga accacctttc gtgcattatc tgaacacatt tagcagcaaa
      961 gaaccgcaac ggggcatggg tttcatgccc aagcggggac tggatgtcag caaatgtgaa
     1021 atcgccaggt tctacaagct acacgaacgg aagtgtgaac ccatcgtcat gactgtacct
     1081 cgaaagtcag atctgttcca ggatgaccta tacccggaca cgcctggccc cgagccagcc
     1141 ctggaagctg atgagtggct atcgggtcag gatgcagaac ctgtgctcat ttcgctgaag
     1201 gaaggctacg ttccccccaa acaccgtgag ttccgggtca ccaaacgcaa catcctagat
     1261 gtgcgcccgc cggccagtcc tcggcgcagc cagtcagcca gcgaagcccc cttgtcgcag
     1321 cagcacaccc tagagacact gctggaggag atgaaggccc tccgagagcg ggtgcaagcc
     1381 caagaggagc gcattaccgc gttggaaaac atgctgtgtg agctggtgga tggcacggac
     1441 tagcactgca cacgcgctgc gaagctctgc acactgcaga cccaacgggg cagggcgcac
     1501 cgattggcag cgccggcttt tggactggga cccgcaccct gcctcccggg gttggaatta
     1561 gtggggagat cgagaagaaa ctccctctcc cacaggaggc ctgaacacac ggatcttaag
     1621 tggctccgta ctaggtcccc ggactttaca ggcctctggg gagcccggga taatgtggcc
     1681 ttagcagtgg tgcttcatgg tgaggtggtg tccctctctg tcccttacct tgggcagagg
     1741 aagcgcttag cattagtgtg atgcctgggg atgctgaggg gcttagtagg cctgacctca
     1801 caagaacagt gattcaacag gtatctccag aatctcagga aatttccaaa aatttctcat
     1861 agtaagaaat tattctgttg ccggagttta acccgctggc ttcaaacatc agtcatggca
     1921 gtgggctctt cccatcttcc cacttccaga gagggcagct tcttggacac aaacagaccc
     1981 caccagagaa atctcaggag aactggcaca gggaagcagg ttcaaaacac acacagacac
     2041 acacacacgc acacacacac acacacacac acacacacac atacacagcc tccaatactc
     2101 tgctgaatct tttaaaaaca ccgaggcata actaatgaaa tattttacta agtacacgtc
     2161 tgtgcctcct acacggagag ccaatatgct gcccccatcc ccagggcact atgagaacca
     2221 ggccttgccc aaactagggg gtacctcagt ccctttttgg aagcctgagg aagcctagca
     2281 aatgcaagct ggactgaggc cccaccacgt agctttttac ccaggtcatc catctttgca
     2341 ctgaagttcc caagacctca cccaccaccc acccaccccc gtgggcactt ctccccaata
     2401 aagttaggta gaaacgcaaa aaaaaaaaaa aaaaaaaaaa aaaa
//
