LOCUS       NM_001012101            2072 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus coronin 2A (Coro2a), mRNA.
ACCESSION   NM_001012101 XM_232991
VERSION     NM_001012101.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2072)
  AUTHORS   Revenu,C., Ubelmann,F., Hurbain,I., El-Marjou,F., Dingli,F.,
            Loew,D., Delacour,D., Gilet,J., Brot-Laroche,E., Rivero,F.,
            Louvard,D. and Robine,S.
  TITLE     A new role for the architecture of microvillar actin bundles in
            apical retention of membrane proteins
  JOURNAL   Mol Biol Cell 23 (2), 324-336 (2012)
   PUBMED   22114352
REFERENCE   2  (bases 1 to 2072)
  AUTHORS   Marshall,T.W., Aloor,H.L. and Bear,J.E.
  TITLE     Coronin 2A regulates a subset of focal-adhesion-turnover events
            through the cofilin pathway
  JOURNAL   J Cell Sci 122 (Pt 17), 3061-3069 (2009)
   PUBMED   19654210
  REMARK    GeneRIF: Coronin 2A and cofilin regulate a subset of
            focal-adhesion-turnover events.
REFERENCE   3  (bases 1 to 2072)
  AUTHORS   Yoon,H.G., Chan,D.W., Huang,Z.Q., Li,J., Fondell,J.D., Qin,J. and
            Wong,J.
  TITLE     Purification and functional characterization of the human N-CoR
            complex: the roles of HDAC3, TBL1 and TBLR1
  JOURNAL   EMBO J 22 (6), 1336-1346 (2003)
   PUBMED   12628926
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1 and BC079209.1.
            
            On Sep 15, 2012 this sequence version replaced NM_001012101.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079209.1, SRR26643293.27667.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-47                JAXUCZ010000005.1  65654556-65654602   c
            48-2072             BC079209.1         1-2025
FEATURES             Location/Qualifiers
     source          1..2072
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     gene            1..2072
                     /gene="Coro2a"
                     /note="coronin 2A"
                     /db_xref="GeneID:313235"
                     /db_xref="RGD:1309719"
     exon            1..154
                     /gene="Coro2a"
                     /inference="alignment:Splign:2.1.0"
     exon            155..328
                     /gene="Coro2a"
                     /inference="alignment:Splign:2.1.0"
     CDS             272..1903
                     /gene="Coro2a"
                     /note="coronin, actin binding protein 2A"
                     /codon_start=1
                     /product="coronin-2A"
                     /protein_id="NP_001012101.2"
                     /db_xref="GeneID:313235"
                     /db_xref="RGD:1309719"
                     /translation="MWNGNSKLRPSPPLLKPNQMSWHPQYRSSKFRHVYGKPASKENC
                     YDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRG
                     NVLDIKWNPFDDFEIASCSEDATIKIWNIPKQLLTRNLTTYRKELMGHARRVGLVEWH
                     PTTANILFSAGYDYKVMVWNLDTKDSVISGPVRTINCHQDVILSMSFNTNGSLLATTC
                     KDRKIRIVDPRLGIVLQEASYKGHRANKVLFLGNLKKLLSTGTSRWNNRQMALWDQDN
                     LSVPLTEEDLDGSSGVLFPFFDSDTSMLYIVGKGDGNIRYYEVSTEKPHLTYLTEYRS
                     YNPQKGIGIMPKRGLDVSSCEIFRFYKLITTKSLIEPVSMIVPRRSESYQEDIYPPTA
                     AAQPSLTAHEWLSGMNRGPIMMSLRPGSELLDPQALPPERLLSNSVVQVSPQPLEPVK
                     QPAEDGDQAPFSLLEEKVTKWTTEHQLEEKSWLTNGFDIFECPPPKTENELLQMFYRQ
                     QEEIRRLRELLIQREVQTKQLELEIKNLRMVLGQF"
     exon            329..529
                     /gene="Coro2a"
                     /inference="alignment:Splign:2.1.0"
     exon            530..646
                     /gene="Coro2a"
                     /inference="alignment:Splign:2.1.0"
     exon            647..796
                     /gene="Coro2a"
                     /inference="alignment:Splign:2.1.0"
     exon            797..976
                     /gene="Coro2a"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1093
                     /gene="Coro2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1094..1198
                     /gene="Coro2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1295
                     /gene="Coro2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1408
                     /gene="Coro2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1499
                     /gene="Coro2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1500..1771
                     /gene="Coro2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1772..2043
                     /gene="Coro2a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caaaatcaga actctcaggg ccttacccat agcctgtggt agagcgacga acttgtccct
       61 gtgtgtctgg aatgtcctca ggtttggggt tttaggtttg ctttcatttt tcttgcagtc
      121 ctagacatta cacctaggga cttgcgcatg ataggctatg ttagaaggtg gtgcttcaga
      181 ccctcccaca aagcacttac agggagcggc ctctgtgccc acaaggtcag attttaagag
      241 gaagaaacaa aagaaaaact tgagctagca gatgtggaat ggcaacagca aactccggcc
      301 cagcccacct ctgctcaaac caaatcagat gtcatggcac ccccagtacc gcagctccaa
      361 gttccgacac gtctacggca agcctgccag caaggagaat tgctacgact ctgtgcccat
      421 cacacgcagc gtccacgaca accacttctg tgctgtgaac ccccacttca tcgctgtggt
      481 cactgaatgt gccggtgggg gcgccttcct tgtcatcccc ttgcaccaga cgggaaagtt
      541 ggaccctcac taccccaagg tctgtgggca cagagggaac gtcttggaca tcaagtggaa
      601 tcctttcgat gactttgaga ttgcctcctg ttcagaagat gccacgatta agatctggaa
      661 catccccaag cagctgctga ccaggaacct cacaacctac aggaaggagt tgatgggtca
      721 cgcacgcagg gtggggctgg tggagtggca ccccacaact gccaacattc tcttcagtgc
      781 tggctatgat tacaaggtga tggtgtggaa cctggacaca aaggactctg taatttctgg
      841 gccggtgagg acaatcaact gtcaccaaga tgtgatcctc tccatgtcct tcaacaccaa
      901 cggcagcctg ctggccacca cctgtaagga ccgcaagatt cggattgttg acccccgact
      961 agggattgtc ctccaggaag ccagctacaa ggggcatcgg gccaacaaag tactgttcct
     1021 ggggaacctc aagaagctgc tatccacggg tacgtcccgc tggaacaacc ggcagatggc
     1081 cctgtgggac caggacaacc tttctgtgcc cctcacagag gaggatttgg atggctcctc
     1141 tggtgtgcta tttcccttct tcgactcgga caccagcatg ctgtacattg tggggaaggg
     1201 agacgggaac atccgctact atgaggtgag cactgagaag cctcacctga cctacctgac
     1261 tgagtaccgc tcctacaacc cacagaaggg gatcggtatc atgccaaaga gaggtctcga
     1321 tgtgtcttcc tgcgagatct tccgcttcta caaactgatc acaaccaaaa gcctcatcga
     1381 gccggtgtcc atgattgtac cccggaggtc agaatcctac caagaggaca tctacccacc
     1441 caccgcagct gcccagccct ccctgacggc ccacgagtgg ctcagcggaa tgaacagagg
     1501 gcctatcatg atgtccctta gacccggctc cgagctgctg gatcctcagg cactgcctcc
     1561 ggagagactc ctctccaatt ctgtggtcca agtttcacct cagcccttag aacccgtgaa
     1621 acagccggcc gaagatggtg accaggcacc cttctctcta ttggaagaga aggtaacgaa
     1681 gtggaccacg gagcatcagc tggaggagaa gtcctggctc accaacggct ttgacatttt
     1741 cgaatgcccg ccaccaaaga cagaaaatga gctgctgcag atgttttacc ggcaacagga
     1801 ggagatccgg aggctccggg agctgttaat ccagagagag gtccagacca agcagctgga
     1861 actggagatc aaaaacctgc ggatggtctt aggacagttc tgagcagagg tctcctccat
     1921 ccttgccctc agggacaccg ctaggctctg tggagaggtc cagaaccaaa ccgcaggtcc
     1981 ccgagaacaa ccactatttc tatattttat accaggaaaa caaaactctg tttctgaaag
     2041 agaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//
